Liver Diseases  >>  oxaliplatin  >>  Phase 2
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21 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
oxaliplatin / Generic mfg.
NCT00070265: Neoadjuvant and Adjuvant Capecitabine and Oxaliplatin in Treating Patients With Resectable Liver Metastases Secondary to Colorectal Cancer

Terminated
2
80
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, capecitabine, CAPE, Ro 09-1978/000, Xeloda, therapeutic conventional surgery, laboratory biomarker analysis
National Cancer Institute (NCI)
Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV Colon Cancer, Stage IV Rectal Cancer
09/04
 
NCT00052364: Oxaliplatin in Treating Patients With Liver Cancer

Completed
2
32
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, laboratory biomarker analysis
National Cancer Institute (NCI)
Adult Primary Hepatocellular Carcinoma, Advanced Adult Primary Liver Cancer, Localized Unresectable Adult Primary Liver Cancer, Recurrent Adult Primary Liver Cancer
01/06
 
NCT00250822: Gemcitabine and Oxaliplatin for Hepatocellular Carcinoma With Platelet Counts Greater Than 100,000 Per Microliter

Completed
2
11
US
Gemcitabine and Oxaliplatin
New Mexico Cancer Care Alliance
Liver Cancer
07/06
07/06
NCT00142467: Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Patients With Hepatocellular Carcinoma

Completed
2
33
US
Gemcitabine, Gemzar, Oxaliplatin, Eloxatin, Bevacizumab, Avastin
Massachusetts General Hospital, Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Genentech, Inc., Sanofi-Synthelabo, Eli Lilly and Company
Hepatocellular Carcinoma
08/06
06/11
NCT00280618: Oxaliplatin in Unresectable Hepatocellular Carcinoma

Completed
2
RoW
Oxaliplatin
Sanofi
Carcinoma, Hepatocellular
11/06
 
NCT00351195 / 2005-003187-32: Etoposide, Oxaliplatin and Capecitabine in Advanced Hepatocellular Carcinoma (HCC)

Terminated
2
39
Europe
Etoposide, Oxaliplatin, Capecitabine
Rigshospitalet, Denmark, Morten Ladekarl, MD, DMSc., Dept. of Oncology, Århus Sygehus, Århus
Hepatocellular Carcinoma
 
04/07
NCT00043004: Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Terminated
2
119
Europe, RoW
bevacizumab, FOLFOX regimen, fluorouracil, leucovorin calcium, oxaliplatin, conventional surgery, radiofrequency ablation
European Organisation for Research and Treatment of Cancer - EORTC, Arbeitsgruppe Lebermetastasen und Tumoren, Institute of Cancer Research, United Kingdom
Colorectal Cancer, Metastatic Cancer
06/07
 
NCT00508872: Folfox-B Study for Patients With Colorectal Liver Metastases

Terminated
2
2
US
5-Fluorouracil, 5-FU, Adrucil, Efudex, Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAb-VEGF, Leucovorin, Citrovorum, Wellcovorin, Oxaliplatin, Eloxatin
M.D. Anderson Cancer Center, Sanofi
Colorectal Liver Metastases
06/09
06/09
NCT00559455: Phase II Study of Eloxatin+5-FU/LV in Patients With Unresectable Hepatocellular Carcinoma

Completed
2
38
RoW
Oxaliplatin, Fluorouracil, Leucovorin
Sanofi
Carcinoma, Hepatocellular
01/10
01/10
NCT00483405: Oxaliplatin, Capecitabine, and Cetuximab in Treating Patients With Advanced Liver Cancer

Checkmark P2 data
Nov 2011 - Nov 2011: P2 data
Completed
2
33
US
cetuximab, Erbitux, capecitabine, Xeloda, oxaliplatin, Eloxatin
UNC Lineberger Comprehensive Cancer Center, Sanofi, Roche Pharma AG, Bristol-Myers Squibb, National Center for Research Resources (NCRR), National Cancer Institute (NCI)
Liver Cancer
02/10
12/10
HEARTO, NCT01348412: Hepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Liver Metastases From Colorectal Cancer After Conventional Chemotherapy Failure

Completed
2
31
Europe
oxaliplatin, raltitrexed, other intravenous chemotherapy drugs
Centre Georges Francois Leclerc, National Cancer Institute, France, Hospira, now a wholly owned subsidiary of Pfizer
Colorectal Cancer, Liver Metastases
12/10
04/18
NCT00743678: Neoadjuvant FOLFOX6 + Cetuximab in Patients With Colorectal Cancer and Unresectable Liver Metastasis

Completed
2
73
RoW
FOLFOX6/cetuximab
Samsung Medical Center
Colorectal Cancer, Unresectable Liver Metastasis
01/12
06/12
PERIMAX, NCT01540435 / 2010-023575-25: Perioperative Treatment of Resectable Liver Metastases

Withdrawn
2
0
Europe
Bevacizumab, VEGF antibody
University of Regensburg, University of Halle Medical Faculty
Colon Cancer Liver Metastasis
05/13
05/13
NCT00832637: Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers

Terminated
2
33
US
Cisplatin, Platinol®, Erlotinib, Tarceva®, Gemcitabine, Gemzar®
New Mexico Cancer Care Alliance
Hepatocellular Carcinoma, Cholangiocellular Carcinoma, Cholangiocarcinoma of the Extrahepatic Bile Duct, Bile Duct Cancer, Periampullary Adenocarcinoma, Gallbladder Cancer, Extrahepatic Bile Duct Cancer
06/13
03/17
NCT01229111: Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers

Terminated
2
14
US
cediranib maleate, AZD2171, Recentin, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, leucovorin calcium, CF, CFR, LV, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU
National Cancer Institute (NCI)
Adult Primary Cholangiocellular Carcinoma, Advanced Adult Primary Liver Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct, Cholangiocarcinoma of the Gallbladder, Localized Unresectable Adult Primary Liver Cancer, Periampullary Adenocarcinoma, Recurrent Adult Primary Liver Cancer, Recurrent Extrahepatic Bile Duct Cancer, Recurrent Gallbladder Cancer, Unresectable Extrahepatic Bile Duct Cancer, Unresectable Gallbladder Cancer
03/14
03/14
NCT01320683: Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Terminated
2
1
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, leucovorin calcium, CF, CFR, LV, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, bevacizumab, anti-VEGF humanized monoclonal antibody, anti-VEGF monoclonal antibody, Avastin, rhuMAb VEGF, yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A, laboratory biomarker analysis, pharmacological study, pharmacological studies, irinotecan hydrochloride, Campto, Camptosar, CPT-11, irinotecan, U-101440E
City of Hope Medical Center, National Cancer Institute (NCI)
Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
12/14
12/14
NCT01581307: Phase II Trial Evaluating OS With Therasphere® + 2nd-Line FOLFOX in Pancreatic Liver Mets

Completed
2
9
US
FOLFOX7 (Folinic acid, 5-Fluorouracil, and Oxaliplatin), Leucovorin, LV, FOL, OX, 5-Fluorouracil (5-FU), FOLFOX, ELOXATIN, TheraSpheres, radiotherapy, radioembolization
H. Lee Moffitt Cancer Center and Research Institute, BTG International Inc.
Liver Cancer, Pancreatic Cancer
02/16
03/16
BOS2, NCT01508000 / 2010-019238-29: Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases

Checkmark For wild-type RAS mutant 1st-line mCRC
Jun 2013 - Jun 2013: For wild-type RAS mutant 1st-line mCRC
Terminated
2
44
Europe
FOLFOX6, Chemotherapy, Bevacizumab, Avastin, Panitumumab, Vectibix, Surgery
European Organisation for Research and Treatment of Cancer - EORTC, Amgen, Roche Pharma AG
Colorectal Cancer Metastatic, Liver Metastases, KRAS Wild Type Colorectal Cancer
09/16
09/16
PACOX, NCT02089633: Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC

Completed
2
17
RoW
PACOX, PEG-BCT-100, Xeloda, Eloxatin
Bio-Cancer Treatment International Limited, The University of Hong Kong
Hepatocellular Carcinoma
09/16
10/16
NCT02015169: Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis

Completed
2
32
RoW
Lapatinib, Tykerb, GSK
Samsung Medical Center
HER2-positive Gastric Cancer Patients With Liver Metastasis
07/17
11/17
NCT00228189: Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients

Completed
1/2
30
Europe
CEA-loaded dendritic cell vaccine
Radboud University Medical Center
Colorectal Cancer, Liver Metastases
11/10
11/10

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