Gastrointestinal Neoplasms  >>  oxaliplatin  >>  Phase 1
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64 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
oxaliplatin / Generic mfg.
NCT01286818: A Study of Irinotecan, Levofolinate, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab (IMC-1121B)

Checkmark ASCO-GI 2013
Jan 2013 - Jan 2013: ASCO-GI 2013
Completed
1b
6
Japan
Ramucirumab (IMC-1121B), IMC-1121B, Ramucirumab, LY3009806, Irinotecan, levofolinate, 5-Fluorouracil (5-FU)
Eli Lilly and Company
Colorectal Carcinoma
02/12
03/12
NCT00660153: Study of Tivozanib (AV-951) Plus FOLFOX6 in Subjects With Advanced Colorectal Cancer and Other Gastrointestinal Cancers

Checkmark P1 data-ASCO
Jun 2012 - Jun 2012: P1 data-ASCO
Completed
1b
30
Europe
Tivozanib (AV-951) plus FOLFOX6
AVEO Pharmaceuticals, Inc.
Colorectal Cancer, Gastrointestinal Cancer
06/12
06/12
NCT02359058: A Study of Ramucirumab Combination Therapy in Japanese Participants Who Have Advanced Stomach Cancer

Completed
1b
18
Japan
Ramucirumab, LY3009806, IMC-1121B, Capecitabine, Cisplatin, S-1, Oxaliplatin
Eli Lilly and Company
Stomach Neoplasms
07/16
11/16
NCT02069041: A Study of Ramucirumab (LY3009806) in Participants With Advanced Liver Cancer

Completed
1b
8
RoW
Ramucirumab, IMC-1121B, LY3009806, FOLFOX4, FOLFOX4 (leucovorin + fluorouracil + oxaliplatin)
Eli Lilly and Company
Carcinoma, Hepatocellular
09/16
09/16
NCT00003427: Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer

Completed
1
36
US
irinotecan hydrochloride, oxaliplatin
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Anal Cancer, Colorectal Cancer, Esophageal Cancer, Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastric Cancer, Gastrointestinal Carcinoid Tumor, Liver Cancer, Pancreatic Cancer, Small Intestine Cancer
04/02
04/02
NCT00003799: Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer

Completed
1
20
US
fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, radiation therapy, irradiation, radiotherapy, therapy, radiation, leucovorin calcium, CF, CFR, LV, therapeutic conventional surgery
National Cancer Institute (NCI)
Adenocarcinoma of the Rectum, Mucinous Adenocarcinoma of the Rectum, Signet Ring Adenocarcinoma of the Rectum, Stage IIA Rectal Cancer, Stage IIB Rectal Cancer, Stage IIC Rectal Cancer, Stage IIIA Rectal Cancer, Stage IIIB Rectal Cancer, Stage IIIC Rectal Cancer
09/03
 
NCT00004257: Oxaliplatin and Fluorouracil Plus Radiation Therapy in Treating Patients With Primary Esophageal or Stomach Cancer

Completed
1
US
fluorouracil, oxaliplatin, conventional surgery, radiation therapy
Albany Medical College, National Cancer Institute (NCI)
Esophageal Cancer
 
01/04
NCT00006391: Oxaliplatin and Topotecan in Treating Patients With Previously Treated Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Completed
1
US
oxaliplatin, topotecan hydrochloride
NYU Langone Health, National Cancer Institute (NCI)
Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer
11/04
 
NCT00081237: OSI-7904L and Oxaliplatin in Treating Patients With Refractory or Recurrent Advanced Colorectal Cancer

Completed
1
15
Europe
OSI-7904L, oxaliplatin
European Organisation for Research and Treatment of Cancer - EORTC
Colorectal Cancer
08/05
 
NCT00008294: Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Completed
1
US
FOLFOX regimen, dexamethasone, floxuridine, fluorouracil, leucovorin calcium, oxaliplatin
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Colorectal Cancer, Metastatic Cancer
05/06
 
NCT00499850: Phase I FOLFOX Combination

Completed
1
18
RoW
ZD6474 (vandetanib), ZACTIMA™, 5-Fluorouracil, 5-FU, Leucovorin, Oxaliplatin
Genzyme, a Sanofi Company
Advanced Colorectal Carcinoma
06/06
04/08
NCT00353262: A Study of Xeloda (Capecitabine) in Combination With Oxaliplatin in Patients With Metastatic Colorectal Cancer.

Completed
1
36
Canada
Avastin, Oxaliplatin, capecitabine [Xeloda]
Hoffmann-La Roche
Colorectal Cancer
09/06
04/08
NCT00300027: Study of BMS-582664 in Combination With Either FOLFIRI or FOLFOX for Gastrointestinal (GI) Malignancies

Terminated
1
50
US
BMS-582664
Bristol-Myers Squibb
Gastrointestinal Neoplasms
12/06
 
NCT00098982: Bortezomib, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Completed
1
16
Europe
bortezomib, fluorouracil, leucovorin calcium, oxaliplatin
European Organisation for Research and Treatment of Cancer - EORTC
Colorectal Cancer
01/07
 
NCT00060411: A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Completed
1
24
US
erlotinib hydrochloride, CP-358,774, erlotinib, OSI-774, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, leucovorin calcium, CF, CFR, LV, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, bevacizumab, anti-VEGF humanized monoclonal antibody, anti-VEGF monoclonal antibody, Avastin, rhuMAb VEGF
National Cancer Institute (NCI)
Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum, Recurrent Colon Cancer, Recurrent Rectal Cancer, Signet Ring Adenocarcinoma of the Colon, Signet Ring Adenocarcinoma of the Rectum, Stage IIIA Colon Cancer, Stage IIIA Rectal Cancer, Stage IIIB Colon Cancer, Stage IIIB Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
07/07
 
NCT00101270: Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Completed
1
24
US
irinotecan hydrochloride, Campto, Camptosar, CPT-11, irinotecan, U-101440E, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP
National Cancer Institute (NCI)
Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Recurrent Childhood Brain Stem Glioma, Recurrent Childhood Cerebellar Astrocytoma, Recurrent Childhood Cerebral Astrocytoma, Recurrent Childhood Ependymoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Liver Cancer, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Malignant Germ Cell Tumor, Recurrent Childhood Medulloblastoma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor, Recurrent Childhood Visual Pathway Glioma, Recurrent Colon Cancer, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Melanoma, Recurrent Nasopharyngeal Cancer, Recurrent Neuroblastoma, Recurrent Osteosarcoma, Recurrent Wilms Tumor and Other Childhood Kidney Tumors, Recurrent/Refractory Childhood Hodgkin Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific
09/07
 
NCT00458809: Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer

Completed
1
16
US
oxaliplatin
Wake Forest University Health Sciences, National Cancer Institute (NCI)
Carcinoma of the Appendix, Colorectal Cancer, Primary Peritoneal Cavity Cancer
11/07
11/07
NCT00403052: A Study of 1018 Immunostimulatory Sequence (ISS) Administered With Irinotecan and Cetuximab to Treat Patients With Previously Treated Metastatic Colorectal Cancer

Terminated
1
14
US
1018 ISS immunostimulatory oligonucleotide
Dynavax Technologies Corporation
Colorectal Neoplasms
12/07
12/07
NCT00084643: GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors

Completed
1
20
US
GTI-2040, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, capecitabine, CAPE, Ro 09-1978/000, Xeloda, pharmacological study, pharmacological studies, laboratory biomarker analysis
National Cancer Institute (NCI)
Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer, Unspecified Adult Solid Tumor, Protocol Specific
04/08
 
NCT00599924: Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors

Checkmark P1 data (Solid tumor)
May 2012 - May 2012: P1 data (Solid tumor)
Completed
1
53
US
sunitinib + FOLFOX, Sunitinib malate, SUTENT, mFOLFOX6
Pfizer
Colorectal Neoplasms, Neoplasms
11/08
11/08
NCT00266097: Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract Cancer

Checkmark Data
May 2012 - May 2012: Data
Completed
1
23
US
erlotinib hydrochloride, gemcitabine hydrochloride, oxaliplatin, radiation therapy, Oxaliplatin
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Pancreatic Cancer
03/09
09/11
NCT01561014: Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Completed
1
9
US
erlotinib hydrochloride, CP-358,774, erlotinib, OSI-774, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, radiation therapy, irradiation, radiotherapy, therapy, radiation, conventional surgery, surgery, conventional, immunohistochemistry staining method, immunohistochemistry, positron emission tomography, FDG-PET, PET, PET scan, tomography, emission computed, computed tomography, tomography, computed, laboratory biomarker analysis, gene expression analysis, fludeoxyglucose F 18, 18FDG, FDG
Wake Forest University Health Sciences, National Cancer Institute (NCI)
Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Adenocarcinoma of the Stomach, Squamous Cell Carcinoma of the Esophagus, Stage II Esophageal Cancer, Stage II Gastric Cancer, Stage III Esophageal Cancer, Stage III Gastric Cancer
03/09
03/09
NCT00631410: Study Of Sunitinib In Combination With Folfox In Patients With Colorectal Cancer

Checkmark P1 data
Mar 2012 - Mar 2012: P1 data
Completed
1
12
Japan
sunitinib + mFOLFOX6
Pfizer
Colorectal Neoplasms
07/09
03/10
NCT01271166: Glivec® Plus m-FOLFOX Avastin® in Advanced Colorectal Cancer

Terminated
1
10
RoW
Imatinib, Fluorouracil, Oxaliplatin, Leucovorin and Bevacizumab
Novartis Pharmaceuticals
Advanced Colorectal Cancer
08/09
 
NCT00220649: Safety Study of Combination Chemotherapy in Patients With Metastatic Solid Tumors or Adenocarcinoma of the Pancreas

Completed
1
25
US
gemcitabine; irinotecan; leucovorin; 5-fluorouracil; oxaliplatin
St. Luke's-Roosevelt Hospital Center, Sanofi
Pancreatic Neoplasms
 
 
NCT00387387: Study On Pazopanib When Given With FOLFOX6 (Fluorouracil, Oxaliplatin, Leucovorin) Or CapeOx (Capecitabine, Oxaliplatin)

Completed
1
50
Europe, RoW
Pazopanib, FOLFOX 6, CapeOx
GlaxoSmithKline
Neoplasms, Colorectal
08/09
08/09
NCT00478634: A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

Completed
1
19
US
RAD001, Cetuximab, Irinotecan
Novartis Pharmaceuticals
Colorectal Cancer, Colorectal Carcinoma, Colorectal Tumors, Neoplasms, Colorectal
09/09
09/09
NCT00507585: Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, Leucovorin, and Avastin

Completed
1
63
US
Fluorouracil, 5-FU, Adrucil, Efudex, 5-fluorouracil, Avastin, Bevacizumab, Leucovorin, Oxaliplatin
M.D. Anderson Cancer Center
Liver Cancer, Advanced Solid Tumors
01/10
01/10
NCT00625092: Hyperthermic Intraperitoneal Oxaliplatin for Peritoneal Malignancies

Completed
1
17
US
fluorouracil, 5-FU, leucovorin calcium, oxaliplatin, Eloxatin, cytoreductive surgery, conventional surgery
Masonic Cancer Center, University of Minnesota
Peritoneal Cavity Cancer
01/10
09/11
NCT00101894: Safety of AMG 706 Plus Panitumumab Plus Chemotherapy in the Treatment of Subjects With Metastatic Colorectal Cancer

Checkmark P2 data - ESMO 2012
Sep 2012 - Sep 2012: P2 data - ESMO 2012
Completed
1
119
US
FOLFOX-4, AMG 706, Panitumumab (Part 1a only), FOLFIRI
Amgen
Rectal Cancer, Colon Cancer
04/10
12/11
NCT00532909: Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer

Completed
1
13
US
Vandetanib, Capecitabine, Oxaliplatin, Bevacizumab
Branimir Sikic, AstraZeneca
Anal, Colon, and Rectal Cancers, Colorectal Neoplasms, Colon/Rectal Cancer
05/10
05/10
NCT00920868: XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib

Completed
1
22
US
dasatinib, Sprycel, bevacizumab, Avastin, Oxaliplatin, Eloxatin, Capecitabine, Xeloda
Herbert Hurwitz, MD, Bristol-Myers Squibb
Solid Tumor, Metastatic Colorectal Cancer
05/10
08/14
NCT00555620: Study Of Sunitinib In Combination With Cisplatin/Capecitabine Or Oxaliplatin/Capecitabine In Patients With Advanced Gastric Cancer

Checkmark Sunitinib+capecitabine/cisplatin OR capecitabine/oxaliplatin in adv gastric cancer
Oct 2013 - Oct 2013: Sunitinib+capecitabine/cisplatin OR capecitabine/oxaliplatin in adv gastric cancer
Completed
1
76
RoW
capecitabine, oxaliplatin, sunitinib malate, Sutent, cisplatin
Pfizer
Stomach Neoplasms
08/10
12/11
RPGOG1, NCT01048320: Gemcitabine and Oxaliplatin (Gem-Ox) Plus Glivec in Gemcitabine-refractory Pancreatic Cancer

Completed
1
36
Europe
Gemcitabine, Oxaliplatin, Imatinib
Royal Marsden NHS Foundation Trust
Advanced Pancreatic Cancer
12/10
12/10
NCT00118261: Erlotinib, Modified FOLFOX6, and Bevacizumab as First-Line Therapy Metastatic Colorectal Cancer

Completed
1
17
US
bevacizumab, erlotinib hydrochloride, fluorouracil, leucovorin calcium, oxaliplatin
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Colorectal Cancer
01/11
01/11
NCT00779311: A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer

Terminated
1
8
US
sorafenib, Nexavar, bevacizumab, Avastin, mFOLFOX6 regimen
Accelerated Community Oncology Research Network, Bayer
Metastatic Colorectal Cancer
03/11
03/11
NCT00861783: Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With Hepatoma

Completed
1
16
US
irinotecan and ON 01910.Na, camptothecin-11, irinotecan HCl, Camptosar, CPT-11, diaminocyclohexane oxalatoplatinum, rigosertib sodium, oxaliplatin and ON 01910.Na, Eloxatin, oxaloplatinum, oxalatoplatin
Onconova Therapeutics, Inc.
Hepatoma, Advanced Solid Tumor
07/11
07/11
NCT00138177: Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors

Completed
1
54
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, leucovorin calcium, CF, CFR, LV, vorinostat, L-001079038, SAHA, suberoylanilide hydroxamic acid, Zolinza, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU
National Cancer Institute (NCI)
Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage III Colon Cancer, Stage III Rectal Cancer, Stage IV Colon Cancer, Stage IV Rectal Cancer, Unspecified Adult Solid Tumor, Protocol Specific
08/11
 
NCT01042691: Isolated Liver Perfusion With Oxaliplatin

Completed
1
10
US
Oxaliplatin
David Bartlett, The Pittsburgh Foundation, Sanofi
Unresectable Colorectal Liver Metastases
11/11
11/11
NCT02720926: Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer

Terminated
1
3
RoW
Xeloda,, capecitabine, Oxaliplatin, TKI258
National Cancer Centre, Singapore, Novartis
Colorectal Cancer, Gastric Cancer
01/12
01/12
NCT00557557: Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases

Checkmark
Apr 2013 - Apr 2013: 
Completed
1
14
US
Drug: 5-FU, Drug: Oxaliplatin
David Bartlett, National Institutes of Health (NIH), National Cancer Institute (NCI)
Colorectal Liver Metastases
03/12
08/14
NCT00934882: Study to Determine Safety, Pharmacokinetics, Pharmacodynamics of BAY73-4506 in Combination With mFOLFOX6 or FOLFIRI

Checkmark Combination with FOLFOX or FOLFIRI as first- or second-line treatment of colorectal cancer
Mar 2013 - Mar 2013: Combination with FOLFOX or FOLFIRI as first- or second-line treatment of colorectal cancer
Checkmark P1 data (CRC)
May 2012 - May 2012: P1 data (CRC)
Completed
1
45
Europe
Regorafenib (BAY73-4506)
Bayer
Colorectal Neoplasms
04/12
04/12
NCT00940758: Phase I and Pharmacokinetic Study of Biweekly PEP02 in mCRC Refractory to 1st-line Oxaliplatin Base Therapy

Completed
1
18
RoW
PEP02
PharmaEngine
Metastatic Colorectal Cancer
05/12
06/14
NCT01164215: Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy

Completed
1
76
US
fluorouracil, 5FU, leucovorin, leucovorin calcium, oxaliplatin, Eloxatin
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI)
Colorectal Cancer, Diarrhea, Neutropenia
11/12
09/13
NCT01383538: FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma

Checkmark FOLFIRINOX combo saridegib
Jun 2012 - Jun 2012: FOLFIRINOX combo saridegib
Completed
1
15
US
FOLFIRINOX, IPI-926, Oxaliplatin, Leucovorin, Irinotecan, 5-FU
Andrew Ko, Infinity Pharmaceuticals, Inc.
Pancreatic Cancer, Adenocarcinoma, Pancreatic Neoplasms
12/12
05/15
NCT00879385: KRAS Wild-type Metastatic Colorectal Cancer Trial

Checkmark +decitabine
Mar 2013 - Mar 2013: +decitabine
Completed
1
21
US
Dacogen™ (decitabine), Vectibix® (panitumumab)
University of Utah, Amgen, Eisai Inc.
Colorectal Cancer
01/13
01/13
NCT00987766: Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer

Completed
1
28
US
erlotinib hydrochloride, gemcitabine hydrochloride, oxaliplatin, laboratory biomarker analysis
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer, Pancreatic Cancer, Periampullary Adenocarcinoma, Small Intestine Cancer
07/13
10/16
NCT01233505: Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Terminated
1
16
US
veliparib, ABT-888, capecitabine, CAPE, Ro 09-1978/000, Xeloda, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, pharmacological study, pharmacological studies, laboratory biomarker analysis
National Cancer Institute (NCI)
Adenocarcinoma of the Pancreas, Adenocarcinoma of the Stomach, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ovarian Mucinous Cystadenocarcinoma, Recurrent Breast Cancer, Recurrent Colon Cancer, Recurrent Gastric Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Pancreatic Cancer, Recurrent Rectal Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Stage IV Colon Cancer, Stage IV Gastric Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Stage IV Pancreatic Cancer, Stage IV Rectal Cancer, Unspecified Adult Solid Tumor, Protocol Specific
10/13
 
NCT01413022: FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Completed
1
44
US
Oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, Irinotecan, Campto, Camptosar, CPT-11, U-101440E, Leucovorin, CF, CFR, LV, Fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, laboratory biomarker analysis, flow cytometry, immunohistochemistry staining method, immunohistochemistry, pharmacological study, pharmacological studies, PF-04136309, PF-4136309
Washington University School of Medicine, National Cancer Institute (NCI)
Pancreatic Neoplasms
10/13
09/16
NCT01693445: S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer

Completed
1
22
RoW
OIS (Oxaliplatin, Irinotecan, S-1), Kabioxaliplatin, Campto, TS-1
Hallym University Medical Center, Jeil Pharmaceutical Co., Ltd., HK inno.N Corporation, Pfizer, Handok Inc.
Gastrointestinal Neoplasms
02/14
08/14
VEOX, NCT01386346: Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer

Completed
1
12
US
Azacitidine, Vidaza®, 5-Azacitidine, Oxaliplatin, Eloxatin, Epirubicin, Ellence, Capecitabine, Xeolda
Weill Medical College of Cornell University, Celgene Corporation
Esophageal Cancer, Malignant Neoplasm of Cardio-esophageal Junction of Stomach
08/14
09/18
NCT01821612: Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients With Pancreatic Cancer

Completed
1
23
US
oxaliplatin, irinotecan, leucovorin, 5-fluorouracil, capecitabine, radiation, surgery, gemcitabine
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage II Pancreatic Cancer, Stage III Pancreatic Cancer
09/14
06/18
NCT01395667: Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy in Combination With Bevacizumab-FOLFOX

Completed
1
15
RoW
CCRT, IMRT, Bevacizumab, Fluorouracil, Leucovorin, Oxaliplatin
National Taiwan University Hospital
Rectal Cancer
03/15
03/15
NCT01446458: Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer

Completed
1
13
US
Modified FOLFIRINOX, modifiedFOLFIRINOX, Stereotactic Body Radiotherapy (SBRT), SBRT
Emory University
Cancer of Pancreas, Cancer of the Pancreas, Neoplasms, Pancreatic, Pancreas Cancer, Pancreas Neoplasms
03/15
03/15
NCT00019773: Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer

Completed
1
US
capecitabine, oxaliplatin
National Cancer Institute (NCI)
Carcinoma of the Appendix, Colorectal Cancer, Small Intestine Cancer
 
 
NCT01571024: BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

Completed
1
17
US
BKM120, buparlisib, mFOLFOX6, Folinic acid (leucovorin), Fluorouracil (5-FU), Oxaliplatin (Eloxatin)
UNC Lineberger Comprehensive Cancer Center
Advanced Solid Tumors, Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer
05/15
03/16
NCT00980239: HAI Irinotecan + IV Bevacizumab, Bevacizumab & Oxaliplatin or Bevacizumab & Cetuximab in Advanced Cancers Metastatic to Liver

Completed
1
115
US
Irinotecan, CPT-11, Camptosar, Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAb-VEGF, Oxaliplatin, Eloxatin, Cetuximab, C225, Erbitux, IMC-C225
M.D. Anderson Cancer Center
Liver Cancer, Advanced Cancer
08/15
08/15
NCT01764477: Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinoma

Completed
1
20
US
PRI-724
Prism Pharma Co., Ltd., inVentiv Health Clinical
Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer, Pancreatic Adenocarcinoma
10/15
10/15
NCT02268825: Phase I Study MK-3475 With Chemotherapy in Patients With Advanced GI Cancers

Terminated
1
39
US
MK-3475
University of Utah, Merck Sharp & Dohme LLC
Advanced GI Cancer
01/17
06/17
PancVax, NCT02548169: Dendritic Cell Vaccine and Chemotherapy for Patients With Pancreatic Cancer

Terminated
1
7
US
DC Vaccine + Standard of Care Chemotherapy
Baylor Research Institute
Pancreatic Cancer
04/17
04/17
PIFA, NCT01719926: Phase I Platinum Based Chemotherapy Plus Indomethacin

Completed
1
13
Europe
Indomethacin
UMC Utrecht
Colorectal Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms
08/17
08/17
NCT02041481: MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer

Checkmark In combination with FOLFOX for colorectal cancer at ASCO GI 2016
Jan 2016 - Jan 2016: In combination with FOLFOX for colorectal cancer at ASCO GI 2016
Completed
1
26
US
MEK inhibitor MEK162, ARRY-162, ARRY-438162, Binimetinib, MEK inhibitor ARRY-438162, MEK162, leucovorin calcium, CF, CFR, LV, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, pharmacological study, pharmacological studies, Laboratory Biomarker Analysis
City of Hope Medical Center, National Cancer Institute (NCI), Array BioPharma
Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
01/18
01/18
NCT02062749: Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma

Completed
1
1
US
Oxaliplatin, Eloxatin
M.D. Anderson Cancer Center
Colorectal Cancer
06/18
06/18
NCT02319018: Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors

Completed
1
14
US
Alisertib, Aurora A Kinase Inhibitor MLN8237, MLN-8237, MLN8237, Fluorouracil, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Laboratory Biomarker Analysis, Leucovorin Calcium, Adinepar, Calcifolin, Calcium (6S)-Folinate, Calcium Folinate, Calcium Leucovorin, Calfolex, Calinat, Cehafolin, Citofolin, Citrec, citrovorum factor, Cromatonbic Folinico, Dalisol, Disintox, Divical, Ecofol, Emovis, Factor, Citrovorum, Flynoken A, Folaren, Folaxin, FOLI-cell, Foliben, Folidan, Folidar, Folinac, Folinate Calcium, folinic acid, Folinic Acid Calcium Salt Pentahydrate, Folinoral, Folinvit, Foliplus, Folix, Imo, Lederfolat, Lederfolin, Leucosar, leucovorin, Rescufolin, Rescuvolin, Tonofolin, Wellcovorin, Oxaliplatin, 1-OHP, Ai Heng, Aiheng, Dacotin, Dacplat, Diaminocyclohexane Oxalatoplatinum, Eloxatin, Eloxatine, JM-83, Oxalatoplatin, Oxalatoplatinum, RP 54780, RP-54780, SR-96669
National Cancer Institute (NCI)
Malignant Digestive System Neoplasm
09/18
09/18

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