AiRuiKa (camrelizumab) / CG Invites, Jiangsu Hengrui Pharma, HLB Bio Group  >>  Phase 1
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30 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
AiRuiKa (camrelizumab) / HLB Bio Group
Icemelting, NCT04393506: Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Completed
1
21
RoW
Camrelizumab, Humanized anti-PD-1 inhibitor, Apatinib, VEGFR2 inhibitor, Radical surgery, Post-operative radiotherapy/chemoradiotherapy
Shanghai Jiao Tong University School of Medicine
Oral Cancer, VEGFR2 Inhibitor, Programmed Cell Death 1 Inhibitor, Inductive Therapy
11/20
11/23
ChiCTR2100046181: A phase IB clinical study of camrelizumab intratumoral injection combined with apatinib in the treatment of malignant ascites in advanced gastric cancer

Recruiting
1
6
 
PD-1 antibody intratumoral injection combined with apatinib
Union Hospital Tongji Medical College Huazhong University of Science and Technology; Union Hospital Tongji Medical College Huazhong University of Science and Technology, The company sponsored the PD-1 drug
Malignant ascites of Gastric cancer
 
 
ChiCTR1900026236: A phase 1b study for fuzuoparib in combination with Albumin Palitaxel and Camrelizumab in the treatment of patients with advanced solid cancer

Not yet recruiting
1
38
 
fuzuoparib (PARP inhibitor) in combination with Albumin Palitaxel and Camrelizumab (PD-1 inhibitor)
The General Hospital of the People's Liberation Army (PLAGH); The General Hospital of the People's Liberation Army (PLAGH), scientific research project
advanced solid cancer
 
 
NCT04665362: IIT Study of M1-c6v1 Combined With SHR-1210 and Apatinib in Patients With HCC

Not yet recruiting
1
10
NA
Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib
Liang Peng, Guangzhou Virotech Pharmaceutical Co., Ltd.
Advanced/Metastatic Hepatocellular Carcinoma
06/22
10/22
ChiCTR2000033727: SHR-1210 combined with apatinib for patients failed with one line therapy of advanced Intrahepatic Cholangiocarcinoma

Not yet recruiting
1
30
 
SHR-1210+apatinib
Third Affiliated Hospital of the Second Military Medical University; Third Affiliated Hospital of the Second Military Medical University, Jiangsu Hengrui Pharmaceutical Co. LTD
Intrahepatic Cholangiocarcinoma
 
 
NCT04508686: Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 1)

Recruiting
1
20
RoW
Capecitabine, camrelizumab
Ruijin Hospital
Advanced Cervical Cancer
08/22
08/24
McCrest-2, NCT04510818: Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 2)

Recruiting
1
20
RoW
Capecitabine, Camrelizumab
Ruijin Hospital
Head and Neck Cancer, Esophageal Squamous Cancer
08/22
08/24
NCT05019534: Tolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal Cancer

Recruiting
1
12
RoW
Vemurafenib Oral Tablet [Zelboraf], Zelboraf, Cetuximab Injection [Erbitux], Erbitux, Camrelizumab
West China Hospital
BRAF V600E-mutated /MSS Metastatic Colorectal Cancer, Vemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal Antibody
08/22
12/22
NCT04564313: Safety and Efficacy of Camrelizumab (Anti-PD-1 Antibody) in Recurrent HCC After Liver Transplantation

Recruiting
1
20
RoW
Camrelizumab treatment
Third Affiliated Hospital, Sun Yat-Sen University
Hepatocellular Carcinoma, Liver Transplantation
09/22
07/23
NCT04625894: The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in Oligometastatic Gastrointestinal Cancer

Not yet recruiting
1
21
RoW
Stereotactic Ablative Radiotherapy (SABR), Camrelizumab for injection (200 mg, iv), D1, Q2W, 14-day cycle
Fudan University
Oligometastatic Gastrointestinal Cancer
12/22
06/23
NCT05008861: Gut Microbiota Reconstruction for NSCLC Immunotherapy

Not yet recruiting
1
20
RoW
Capsulized Fecal Microbiota Transplant, Capsulized FMT, Anti-programmed cell death protein 1/programmed death-ligand 1 monoclonal antibody, Anti-PD-1/PD-L1 mAb, Anti-PD-1/PD-L1, Pembrolizumab, Nivolumab, Durvalumab, Sintilimab, Tislelizumab, Camrelizumab, Platinum based chemotherapy, Platinum based Chemotherapy drugs
Shanghai Zhongshan Hospital
Non-Small Cell Lung Cancer
12/22
12/22
NCT05001412: Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLC

Recruiting
1
36
RoW
Camrelizumab; apatinib; carboplatin; etoposide
Zhou Chengzhi, Jiangsu Hengrui Pharmaceutical Co., Ltd.
Extensive Stage Small Cell Lung Cancer
01/23
01/24
NCT05198817: A Trial of SHR-2002 Injection or Combined With Other Anti-cancer Medication in Advanced Malignant Tumors of Patients

Enrolling by invitation
1
240
RoW
SHR-2002 injection、Camrelizumab for Injection, SHR-1316 injection, SHR-1701 injection
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Advanced Malignant Tumors
01/23
06/23
PIANO, NCT03491631: Phase I Study of SHR9146 + SHR-1210 +/- Apatinib in Patients With Advanced Solid Tumors

Active, not recruiting
1
23
RoW
SHR9146+SHR-1210, SHR9146+SHR-1210+Apatinib
Jiangsu HengRui Medicine Co., Ltd.
Tumor, Solid, Cancer, Metastatic, Neoplasm Malignant
06/23
09/23
McCrest-3, NCT04932187: Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 3)

Recruiting
1
20
RoW
Capecitabine, Camrelizumab
Ruijin Hospital
Hepatobiliary, Pancreatic and Other Gastrointestinal Carcinoma (Non-stomach, Non-esophagi)
07/23
07/25
NCT05429398: A Study of Linperlisib Combination With Camrelizumab in Patients With Solid Tumor

Not yet recruiting
1
118
NA
Linperlisib Tablet, Camrelizumab for Injection
Shanghai YingLi Pharmaceutical Co. Ltd.
Advanced Solid Tumor
08/23
05/24
NCT05643417: Camrelizumab Combined With Bevacizumab and HAIC in Patients With Metastatic Liver Cancer Who Failed Standard Therapy

Not yet recruiting
1
80
RoW
HAIC、Bevacizumab、Camrelizumab, Camrelizumab brand name: ai rui ka; Bevacizumab brand name: ai rui tuo
Fudan University
Metastatic Liver Cancer
10/23
10/24
NCT05799183: A SHR-1210 BE Study on Healthy Subjects

Recruiting
1
118
RoW
SHR-1210
Jiangsu HengRui Medicine Co., Ltd.
Advanced Tumors
10/23
11/23
ChiCTR2200060165: Clinical study of camrelizumab combined with nabTC in the long-term neoadjuvant treatment of patients with stage II-III operable lung adenocarcinoma

Not yet recruiting
1
30
 
Carrilizumab + albumin-paclitaxel + carboplatin was given. After 2 weeks of treatment, the drug was stopped and lung cancer resection was performed
First Affiliated Hospital of Anhui Medical University; First Affiliated Hospital of Anhui Medical University, None
non-small cell lung cancer (NSCLC)
 
 
NCT06326736: Study of Neoantigen mRNA Vaccines in Patients With Resectable Pancreatic Cancer

Recruiting
1
12
RoW
Surgery, Surgical resection, Camrelizumab, PD-1 inhibitor, SJ-Neo006, Neoantigen mRNA Vaccines, Gemcitabine+Abraxane, chemotherapy
Jinling Hospital, China, Jiangsu Synthgene Biotechnology Co.Ltd.
Pancreatic Cancer
12/25
12/26
NCT06356701: Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC

Recruiting
1
120
RoW
Cancer nutritional treatment regimen (Spirulina Bifidobacterium Capsules, Fish Oil Grape Seed Blueberry Soft Capsules, Ganoderma Spore Oil Soft Capsules)
The First Affiliated Hospital of Dalian Medical University
Long-Term Effects Secondary to Cancer Therapy
12/24
12/25
NCT06346808: Oncolytic Virus Plus Anti-PD1 and Chemotherapy as Preoperative Therapy for Patients With BRPC/LAPC

Not yet recruiting
1
20
RoW
Oncolytic virus Plus Anti-PD1 and Chemotherapy
Sichuan University
Pancreatic Cancer
05/26
05/27
NCT04074564: MASCT-I Combined With Apatinib and/or Camrelizumab in the Treatment of Bone and Soft Tissue Sarcoma

Recruiting
1
60
RoW
MASCT-I, Camrelizumab,Apatinib
HRYZ Biotech Co.
Sarcoma
08/24
12/24
NCT06109207: Neoadjuvant Camrelizumab With Dalpiciclib for Resectable Esophageal or Head and Neck Squamous Cell Carcinomas

Recruiting
1
12
RoW
Camrelizumab, Dalpiciclib 100mg, Dalpiciclib 150mg
West China Hospital
Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
10/24
10/25
ChiCTR2200060742: Effects of thalidomide combined with Camrelizumab on the incidence and efficacy of RCCEP in patients with non-small cell lung cancer

Not yet recruiting
1
100
 
Thalidomide combined with carrilizhu
The Third Affiliated Hospital of Shandong First Medical University; The Third Affiliated Hospital of Shandong First Medical University, self-funded
reactive cutaneous capillary endothelial proliferation
 
 
CCGLC-003, NCT05031949: Hyperbaric Oxygen Therapy Combined Camrelizumab in Patients With Advanced/Metastatic Hepatocellular Carcinoma

Recruiting
1
20
RoW
hyperbaric oxygen therapy plus Camrelizumab
Zhang Bi Xiang, MD
Combinational Immunotherapy, Hepatocellular Carcinoma Non-Resectable, Hyperbaric Oxygen Therapy
12/24
06/25
ChiCTR2000040646: Camrelizumab and apatinib combined with chemotherapy (mFOLFOX6) in neoadjuvant therapy for locally advanced right-sided colon cancer

Not yet recruiting
1
64
 
PD-1+Apatinib+Chemotherapy
The First Affiliated Hospital, Zhejiang University School of Medicine; The First Affiliated Hospital, Zhejiang University School of Medicine, Third Party Funded Drugs
colon cancer
 
 
ChiCTR2300069990: Carrilizumab combined with Apatinib in the treatment of RCC with inferior vena cava cancer thrombus: a single-arm multicenter exploratory clinical study

Not yet recruiting
1
48
 
Carrilizumab combined with Apatinib neoadjuvant therapy
Peking University Third Hospital; Peking University Third Hospital, National Nature Science Foundation of China /Wu Jieping Medical Foundation/Innovative Transformation Project of Haidian District
Renal Cell Carcinoma
 
 
ChiCTR2300073069: Multicenter, single-dose, randomized, open, parallel-designed bioequivalence study of carrilizumab for injection with old and new processes in healthy male subjects

Not yet recruiting
1
118
 
A single intravenous administration of 20 mg was performed, and 12 subjects were randomly divided into 1:1 groups to receive carrilizumab (old process) and carrilizumab (new process) at random. The pre-trial study procedure was the same as the formal trial. ;A single intravenous administration of 20 mg was performed, and 12 subjects were randomly divided into 1:1 groups to receive carrilizumab (old process) and carrilizumab (new process) at random. The pre-trial study procedure was the same as the formal trial. ;Test preparation (T) was a new process of carrilizumab; The reference preparation (R) was the old process carrilizumab. Using a single intravenous administration of 20 mg, 106 healthy male subjects were randomly divided into 1:1 groups to receive carrilizumab (old process) and carrilizumab (new process), and the formal trial study process was the same as the preliminary trial. ;Test preparation (T) was a new process of carrilizumab; The reference preparation (R) was the old process carrilizumab. Using a single intravenous administration of 20 mg, 106 healthy male subjects were randomly divided into 1:1 groups to receive carrilizumab (old process) and carrilizumab (new process), and the formal trial study process was the same as the preliminary trial.
Clinical Trial Center of Third Xiangya Hospital of Central South University; Third Xiangya Hospital, Central South University, Suzhou Shengdia Biomedicine Co., LTD
Malignant tumor
 
 
NCT06121557: Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Recruiting
1
24
RoW
Surgery for harvesting tumor-draining lymph nodes, Cyclophosphamide, Fludarabine, Tumor-draining lymph node-derived lymphocyte (LNL), LNL, Interleukin-2, IL-2, Camrelizumab, SHR-1210, Chemotherapeutic drug, ADC or PARP inhibitor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Neoplasms
12/26
12/31

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