| haloperidol / Generic mfg. |
ChiCTR2200061843: A 24-Week, Randomized, Open-Label, Haloperidol-Control Study to Evaluate the Efficacy of Quetiapine in Improving Social Cognitive Function of Patients with Schizophrenia |
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| Completed | 4 | 62 | | treatment with quetiapine ;treatment with haliperidol | Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Xi’An Janssen Pharmaceutical Ltd. | Schizophrenia | | | | |
| Completed | 4 | 3000 | | Perphenazine 16-64 mg/d (N=250) or Haloperidol 6-20 mg/d (N=250) ;Risperidone 2-6mg/d ;Olanzapine 5-20 mg/d ;Quetiapine 400-750mg/d ;Aripiperazole 10~30 mg/d ;Ziprasidone 80-160 mg/d | The Sixth Hospital / Institute of Mental Health, Peking University; The Ministry of Science and Technology, The National High Technology Research and Development Program of China (863 program) | Schizophrenia | | | | |
ChiCTR-TRC-09000379: Effect of haloperidol on early postoperative delirium and late postoperative outcomes in elderly patients after non-cardiac surgery: a multi-central, randomized controlled trial |
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| Completed | 4 | 500 | | Haloperidol is administrated (IV bolus 0.5mg followed by continuously IV infusion 0.1mg/h) until 24 hours after surgery. ;Normal saline is administrated intravenously in the same rate and volume as that in Group A. | Peking University First Hospital; Peking University Third Hospital, Clinical Research Fund of Peking University First Hospital | Patients admitted to the SICU after major non-cardiac (intra-thoracic or intra-abdominal) surgery under general anesthesia. | | | | |
ChiCTR2200060542: A 16-Week, Randomized, Open label, Haloperidol-Controlled Study to Evaluate the Efficacy of Ziprasidone in Improving Social Cognitive Function of Patients with Schizophrenia |
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| Completed | 4 | 60 | | Ziprasidone treatment ;Haloperidol treatment | Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Pfizer Inc. | Schizophrenia | | | | |
2007-000579-40: Effects of atypical versus typical neuroleptics on motivation, hedonia, and social cognition in patients with schizophrenia – an fMRI study |
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| Ongoing | 4 | 34 | Europe | Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal | Charité Universitätsmedizin Berlin | Schizophrenia | | | | |
2007-003342-15: A Randomized, Open-Label Study Comparing the Effectiveness of Olanzapine Pamoate Depot with Haloperidol Decanoate in the Treatment of Schizophrenia |
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| | 4 | 30 | Europe | Olanzapine Pamoate Depot, Haloperidol, OLANZAPINE, Haloperidol decanoate, LY170053 Compound 426906, LY170053, Haldol, ZYPREXA 5 mg coated tablets, Haldol Decanoate, Haldol, ZYPREXA 5 mg coated tablets, Haldol Decanoate | Eli Lilly and Company Limited | Schizophrenia | | 06/08 | | |
2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD |
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| Ongoing | 4 | 300 | Europe | Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary) | King\'s College London, North Essex Partnership NHS Foundation Trust | Alzheimer\'s disease | | | | |
2014-001545-25: Studying the effect of haldol and lorazepam on standing balance measured with the BalRoom in healthy elderly. |
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| Ongoing | 4 | 12 | Europe | Haloperidol, Lorazepam, Haloperidol, Lorazepam | Centre for Human Drug Research, Centre for Human Drug Research | Healthy volunteers (balance disorders) | | | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
ChiCTR-IPR-15007635: An 16-Week, Randomized, Open label, Haloperidol-Controlled Study to Evaluate the Efficacy of Paliperidone In Improving Social Cognitive Function of Patients with Schizophrenia |
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| Completed | 4 | 60 | | treatment with paliperidone ;treatment with haliperidol | Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Xi’An Janssen Pharmaceutical Ltd | Schizophrenia | | | | |
2017-003115-20: Effectiveness of haloperidol for the treatment of acute confusional state (delirium) in patients treated at the intensive care |
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| Ongoing | 4 | 742 | Europe | Solution for infusion, Haloperidol | Erasmus Medical Center Rotterdam, ZonMw | Delirium, Acute confusion, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-002406-12: HAMLETT. Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment. A study comparing continuation versus discontinuation/dose reduction of antipsychotic medication in patients remitted after a first episode of psychosis HAMLETT. Handling Antipsychotic Medication: Lange termijn evaluatie van specifiek toegepaste medicatie. Vergelijking tussen het doorgaan met antipsychotische medicatie bij patiënten die hersteld zijn van eerste psychotische episode en vroegtijdig afbouwen/stoppen. |
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| Not yet recruiting | 4 | 512 | Europe | RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE, CID5073, CID135398745, CID5002, CID60795, CID3559, CID5355, CID115237, CID16362, CID213046, CID135398737, CID2159, CID5467, CID60149, CID667467, CIS5311507, Tablet, RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE | University Medical Center Groningen, ZonMw | HAMLETT compares regular treatment guidelines for patients in remission after a first episode of psychosis, namely continuation with antipsychotic medication for at least one year, with early dose reduction/discontinuation. HAMLETT vergelijkt de reguliere behandeling van patiënten in remissie na een eerste psychotische episode zoals beschreven in de richtlijnen, namelijk het continueren van antipsychotica voor minstens 1 jaar, met het vroegtijdig afbouwen/stoppen met medicatie., HAMLETT compares continuation versus early discontinuation of antipsychotic medication in patients who have recovered from their first episode of psychosis. HAMLETT vergelijkt de reguliere behandeling van patiënten die hersteld zijn van een eerste psychose, namelijk minimaal 1 jaar antipsychotica gebruiken, met vroegtijdig afbouwen/stoppn met medicatie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Active, not recruiting | 4 | 1000 | Europe | Haloperidol Injection, Serenase, Saline (0,9%) | Zealand University Hospital, Centre for Research in Intensive Care (CRIC), Copenhagen Trial Unit, Center for Clinical Intervention Research, Scandinavian Critical Care Trials Group, The Danish Centre of Applied Social Science (VIVE) | Delirium | 07/22 | 07/23 | | |
NCT04764344: Haloperidol for the Treatment of Nausea and Vomiting in the ED |
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| Completed | 4 | 60 | US | Haloperidol, Haldol, Ondansetron | Western Michigan University School of Medicine | Vomiting, Nausea, Abdominal Pain, Cannabis Use | 05/23 | 05/23 | | |
| Not yet recruiting | 4 | 160 | | 100,000 units of ulinastatin were continuously pumped during the operation, and the postoperative analgesic pump was Apon electronic analgesic pump ZZB-Ⅰ150ml. 500,000 units of ulinastatin, 2mg of haloperidol, 37.5mg of dolastron and 12mg of morphine were added into the pump. The first dose of 5ml was given ten minutes before the end of the procedure.; the postoperative analgesic pump was Apon electronic analgesic pump ZZB-Ⅰ150ml,2mg of haloperidol, 37.5mg of dolastron and 120mg of morphine were added into the pump. The first dose of 5ml was given ten minutes before the end of the procedure. | Tianjin Jizhou District People's Hospital; Tianjin Jizhou District People's Hospital, Tianjin Jizhou District People's Hospital | postoperative pain | | | | |
NCT06395428: Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department |
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| Not yet recruiting | 4 | 75 | NA | Haloperidol, Haldol, Ketorolac Tromethamine, Toradol | Western Michigan University School of Medicine, Bronson Methodist Hospital | Back Pain, Chronic Pain | 04/25 | 04/27 | | |
ChiCTR2200063052: A comparative study of olanzapine oral solution film, ziprasidone mesylate for injection and haloperidol injection in the treatment of acute agitation symptoms of schizophrenia |
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| Not yet recruiting | 4 | 60 | | Olanzapine oral dissolution film ;ziprasidone injection ;haloperidol injection | The Third Hospital of Fuyang; The Third Hospital of Fuyang, In-Hospital Funding | Schizophrenia | | | | |
2014-001157-17: Efficacy of intranasal administration of haloperidol compared to intramuscular administration in agitated schizophrenic patients Eficacia de la administración de haloperidol intranasal comparada con la administración intramuscular en pacientes esquizofrénicos agitados |
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| Ongoing | 3 | 40 | Europe | Nebulisation solution, Solution for injection | Fundació Parc TaulÃ, Fundació Parc Taulà | Agitation in schizophrenic patients Agitación en pacientes esquizofrénicos, Agitation in schizophrenic patients Agitación en pacientes esquizofrénicos, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT04081545: Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery |
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| Active, not recruiting | 3 | 184 | US | Opioid Anesthetics, Opioid-based regimen, Non Opioid Analgesics, Opioid-free regimen | Christine Oryhan, Virginia Mason Hospital/Medical Center | Opioid Use, Unspecified, Bariatric Surgery Candidate, Anesthesia | 03/23 | 06/23 | | |
NCT04833023: HALO Trial: Haloperidol vs Olanzapine in Hyperactive Delirium in Palliative Care Patients; A Multi-Centre, Randomised-Controlled Trial |
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| Recruiting | 3 | 72 | RoW | Haldol 2mg/ml oral solution, Olanzapine Actavis 5mg orodispersible tablet | Tan Tock Seng Hospital | Haloperidol, Advanced Cancer, Hyperactive Delirium, Olanzapine, End-stage Organ Disease | 12/24 | 12/24 | | |
NCT05690698: Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium |
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| Completed | 3 | 100 | RoW | Quatiapine, Haloperidol | Alexandria University, Suez Canal University, Gezira University | Hyperactive Delirium | 07/23 | 07/23 | | |
NCT05803642: A Study of Olanzapine in Patients With Acute Agitation |
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| Not yet recruiting | 3 | 318 | NA | Olanzapine, Haloperidol | Qilu Pharmaceutical Co., Ltd. | Acute Agitation | 05/24 | 07/24 | | |
NCT06370442: Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult |
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| Not yet recruiting | 3 | 60 | NA | Dexmedetomidine, Precedex, Lorazepam, Ativan, Haloperidol, Haldol | State University of New York - Upstate Medical University | Altered Mental Status | 05/25 | 09/25 | | |
| Recruiting | 3 | 1000 | Europe | Dexamethasone, Dexavit, Backrest elevation, Early wakeup call, Olanzapine | Christian Hassager | Out-Of-Hospital Cardiac Arrest, Post-Cardiac Arrest Syndrome | 09/27 | 12/27 | | |
R21NR016736, NCT03021486: Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer |
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| Active, not recruiting | 2/3 | 70 | US | Chlorpromazine, Chlor-PZ, Thorazine, Haloperidol, Haldol, McN-JR-1625, R 1625, R-1625, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI), National Institutes of Health (NIH), National Institute of Nursing Research (NINR) | Advanced Malignant Neoplasm, Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm | 06/21 | 06/25 | | |
2021-001333-38: Clinical trial to study the effect of an already authorized drug on other pathologies by administering it to people with a recent diagnosis of schizophrenia. Ensayo clínico para estudiar el efecto que tiene un fármaco ya autorizado en otras patologías administrándolo en personas con reciente diagnóstico de esquizofrenia. |
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| Not yet recruiting | 2/3 | 50 | Europe | VORTIOXETINA, HALOPERIDOL, Pimozida, Olanzapina, Risperidona, Chlorpromazine, Thioridazine, Quetiapine, Ziprasidone, aripiprazole, N06AX26, N05AD01, NO5AG02, NO5A H03, NO5AX08, N05AA01, N05AC02, N05AH04, N05AE04, N05AX12, Tablet, Capsule, hard, BRINTELLIX | Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI), Consejería de salud | Early schizophrenia Esquizofrenia temprana, Newly evolving schizophrenia Esquizofrenia de reciente evolución, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT06168773: Combination of Haloperidol and Magnesium for Delirium Prevention in Critically Ill Elderly |
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| Completed | 2/3 | 135 | RoW | Haloperidol Injection, Magnesium Sulphate | Ain Shams University | Delirium in Old Age | 10/23 | 11/23 | | |
NCI-2018-02438, NCT03743649: Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care |
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| Active, not recruiting | 2/3 | 110 | US, RoW | Haloperidol, Haldol, McN-JR-1625, R 1625, R-1625, Lorazepam, Ativan, Placebo, placebo therapy, PLCB, sham therapy, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm | 12/25 | 12/26 | | |
NCT05431595: Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy |
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| Active, not recruiting | 2/3 | 11 | US | Haloperidol, Chlorpromazine, Chlorpromazine hydrochloride, Thorazine®, Valproate, Depakene, Valproate Acid, Placebo | M.D. Anderson Cancer Center, Cancer Prevention Research Institute of Texas | Delirium, Epileptics, Neuroleptics | 02/27 | 02/27 | | |
| Recruiting | 2 | 24 | | | The University of Technology Sydney , The University of Technology Sydney | Nausea
, Advanced Cancer | | | | |
NCT01949662: Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer |
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| Active, not recruiting | 2 | 93 | US | Lorazepam, Placebo, Haloperidol decanoate, Questionnaires, Surveys | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Advanced Cancers | 08/16 | 01/26 | | |
CLOZ-AID, NCT04529226: Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis |
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| Active, not recruiting | 2 | 75 | Europe | Clozapine, Nemex, Leponex, haloperidol, pimozide, olanzapine, risperidone, amisulpride | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Psychosis, Intellectual Disability | 01/25 | 12/25 | | |
NCT06428084: Comparative Efficacy of Dexamethasone - Ondansetron Versus Dexamethasone - Haloperidol in Reducing PONV |
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| Completed | 2 | 38 | RoW | Ondansetron, Haloperidol | Universitas Padjadjaran | Laparoscopic Cholecystectomy | 02/24 | 02/24 | | |
NCT05065567: Haloperidol, Droperidol, Ondansetron in Cannabis Hyperemesis |
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| Terminated | 2 | 38 | US | Droperidol, Haloperidol, Ondansetron 8mg | Spectrum Health - Lakeland | Cyclic Vomiting Syndrome | 11/23 | 11/23 | | |
| Recruiting | 2 | 80 | RoW | Haloperidol Solution, Olanzapine Tablets | HCA Hospice Care | Delirium, Terminal Illness | 05/24 | 05/24 | | |
NCT06218524: The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM |
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| Not yet recruiting | 2 | 200 | NA | Haloperidol Tablets, Temozolomide | Southern Medical University, China | Glioblastoma Multiforme | 12/27 | 07/28 | | |
ChiCTR2000029303: Bioequivalence of haloperidol Tablets(Fasting) in the Healthy Human Body: A randomized cross-over controlled trial |
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| Not yet recruiting | 1 | 24 | | Phase I or II giving Haloperidol Tablets (Haloperidol Tablets 5 mg/Tablet) (Vickmans Laboratories Ltd., Hong Kong) versus Phase II or I giving Haloperidol Tablets (Haloperidol 5 mg/Tablet) (Janssen Farmacêutica Portugal, Lda.) | Xiangya Boai Rehabilitation Hospital; Vickmans Laboratories Ltd, Vickmans Laboratories Ltd. | Pharmacokinetics and Bioequivalence Study in human | | | | |
NCT04071639: Symptomatic Therapy for Patients With Huntington's Disease |
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| Recruiting | 1 | 60 | RoW | Haloperidol 2Mg Tab, Haloperidol Tables, H31021234, Risperidone 1Mg Tab, Risperidone, H20010309, Zoloft 50Mg Tablet, Sertraline Hydrochloride Tablets, H10980141, Idebenone, Idebenone,H10970363, Deutetrabenazine Oral Tablet [Austedo], Deutetrabenazine | Second Affiliated Hospital, School of Medicine, Zhejiang University | Huntington Disease | 12/24 | 12/24 | | |
NCT01359293: Effects of Paliperidone Palmitate Versus Oral Antipsychotics on Clinical Outcomes and MRI Measures |
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| Recruiting | N/A | 120 | US | paliperidone palmitate, Sustenna, oral antipsychotics | University of Iowa, Wishard Health Services | Schizophrenia, Schizophreniform | 04/14 | 12/14 | | |
ChiCTR1800019713: Addition of haloperidol to ondansetron and dexamethasone to prevent postoperative nausea and vomiting in female smoking patients following laparoscopic surgery |
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| Not yet recruiting | N/A | 210 | | 4mg ondansetron ;4mg ondansetron+8mg dexamethasone ;4mg ondansetron+8mg dexamethasone+2mg haloperidol | Second Hospital of Tianjin Medical University; Second Hospital of Tianjin Medical Unviersity, Self-financing | postoperative nausea and vomiting | | | | |
| Completed | N/A | 150 | Europe | placebo, haloperidol 2mg, propranolol 40mg | Maastricht University | Motivation | 04/23 | 08/23 | | |
| Completed | N/A | 105 | Europe | Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery, the usual unit treatment | University of Huelva | Delirium, Postoperative Delirium, Cardiac Surgery | 06/23 | 06/23 | | |
NCT05996887: Impact of ERAS on Postoperative Nausea and Vomiting After Sleeve |
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| Recruiting | N/A | 60 | RoW | standard care protcol, control, enhanced recovery protocol, ERAC | Minia University | Nausea and Vomiting, Postoperative | 12/23 | 01/24 | | |
IM-ZBULLE, NCT05995457: The Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate |
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| Not yet recruiting | N/A | 84 | Europe | Intramuscular injection of Haloperidol decanoate using the "Z-track" and "Airlock" techniques, Intramuscular injection of Haloperidol decanoate using standard techniques | Centre Hospitalier St Anne, Groupe Hospitalier Paul Guiraud, Etablissement Public de Santé Barthélemy Durand | Schizophrenia; Psychosis | 09/24 | 11/24 | | |
| Recruiting | N/A | 200 | US | Antipsychotics, Non-antipsychotic medication, Antidepressants, Benzodiazepines, No Medication | Icahn School of Medicine at Mount Sinai, Erasmus Medical Center, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Antipsychotics, Pregnancy | 08/27 | 08/27 | | |
ACTRN12613000006741: The impact of a core medicines list on access to medicines for palliative patients within their home environment |
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| Not yet recruiting | N/A | 25 | | | Kate Swetenham, Southern Adelaide Palliative Service | Palliative Care, Pain, Dyspnoea, noisy Breathing, nausea and vomiting, delirium and agitation | | | | |
ACTRN12607000280404: A single-centre, randomized comparsion of the Efficacy and Safety of Intramuscular Olanzapine and Haloperidol in Treating Acutely Agitated patients in Emergency Department |
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| Not yet recruiting | N/A | 280 | | | Peninsula Health (Emergency Department), Peninsula Health | Sedation for the acutely agitated patients | | | | |