Vascular Diseases  >>  Activase (alteplase)  >>  Phase 3
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7 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
NCT02182011: A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)

Completed
3
49
Europe
Tenecteplase, Alteplase, Streptokinase
Boehringer Ingelheim
Myocardial Infarction
06/01
 
NCT00147316: Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Completed
3
103
Japan
Alteplase
Mitsubishi Tanabe Pharma Corporation, Kyowa Hakko Kogyo Co., Ltd.
Cerebral Infarction, Brain Ischemia
 
09/03
NCT00148460: Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction

Completed
3
270
RoW
TNK-tPA, rt-PA
Boehringer Ingelheim
Myocardial Infarction
 
02/06
NCT00153036 / 2005-003176-38: Rt-PA in the Treatment of Acute Ischemic Stroke

Completed
3
821
Europe
rt-PA 0.9 mg/kg verum or placebo Intravenous
Boehringer Ingelheim
Cerebrovascular Accident
02/08
 
CERE-LYSE-1, NCT00840671 / 2004-001729-11: Combined Treatment With Alteplase (Rt-PA) and Cerebrolysin® in Acute Ischemic Hemispheric Stroke

Completed
3
119
Europe, RoW
Cerebrolysin, 0.9% Saline Solution, NaCl
Ever Neuro Pharma GmbH, JSW-Research Forschungslabor GmbH, Parkring 12, 8074 Grambach
Stroke
03/08
07/08
ATTRACT, NCT00790335: Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis

Completed
3
692
US
Recombinant tissue plasminogen activator (rt-PA), rt-PA, recombinant tissue plasminogen activator, Activase, Alteplase
Washington University School of Medicine, McMaster University, Ontario Clinical Oncology Group (OCOG), National Heart, Lung, and Blood Institute (NHLBI), BSN Medical Inc, Genentech, Inc., Medtronic - MITG, Boston Scientific Corporation, Mid America Heart Institute, Society of Interventional Radiology Foundation, Massachusetts General Hospital
Deep Vein Thrombosis, Venous Thrombosis, Postphlebitic Syndrome, Venous Thromboembolism, Post Thrombotic Syndrome
01/17
01/17
PRISMS, NCT02072226: A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

Terminated
3
313
US
Alteplase, Activase; RO5532960, Alteplase Placebo, Aspirin, Aspirin Placebo
Genentech, Inc.
Stroke
03/17
03/17

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