| Completed | 3 | 500 | Canada, US, Europe, RoW | Alteplase, Cathflo Activase, rt-PA, Normal saline | Johns Hopkins University, National Institute of Neurological Disorders and Stroke (NINDS), Genentech, Inc., Emissary International LLC | Intraventricular Hemorrhage | 07/15 | 01/16 | | |