Dyslipidemias  >>  pioglitazone  >>  Phase 3
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
pioglitazone / Generic mfg.
NCT00521742: Efficacy of Pioglitazone Compared to Glyburide in Treating Subjects With Type 2 Diabetes Mellitus and Mild Cardiac Disease

Completed
3
300
US
Pioglitazone, Actos, AD4833, Glyburide
Takeda, Takeda Pharmaceuticals North America, Inc.
Diabetes Mellitus
01/03
01/03
NCT00521820: Safety Comparison of Pioglitazone and Glyburide in Type 2 Diabetes Subjects With Mild to Moderate Congestive Heart Failure

Terminated
3
518
US
Pioglitazone, Actos, AD-4833, Glyburide
Takeda
Diabetes Mellitus
10/03
10/03
NCT00331487: Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia

Completed
3
719
US
Pioglitazone, Actos, AD4833, Rosiglitazone
Takeda, Eli Lilly and Company
Diabetes Mellitus
03/04
03/04
PROactive, NCT00174993: Efficacy of Pioglitazone on Macrovascular Outcome in Patients With Type 2 Diabetes

Completed
3
4373
Europe
Pioglitazone, Actos, AD4833, Placebo
Takeda, Eli Lilly and Company
Diabetes Mellitus
01/05
01/05
NCT00286494 / 2005-004669-40: Study of Alogliptin Combined With Pioglitazone in Subjects With Type 2 Diabetes Mellitus

Completed
3
493
US, Europe, RoW
Alogliptin and pioglitazone, SYR110322, Alogliptin, AD-4833, Pioglitazone, Actos, SYR-322
Takeda
Diabetes Mellitus
08/07
08/07
NCT00395512 / 2006-005492-17: Efficacy of Alogliptin With Pioglitazone (Actos®) in Subjects With Type 2 Diabetes Mellitus

Completed
3
655
US, Europe, RoW
Alogliptin, SYR-322, Pioglitazone, Actos, AD4833, Placebo
Takeda
Diabetes Mellitus
02/08
02/08
PRISMA, NCT00772174 / 2006-000725-54: Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes

Completed
3
418
Europe
Pioglitazone and Metformin, ACTOS®, AD4833, Metformin
Takeda
Diabetes Mellitus
02/08
02/08
NCT00770952 / 2006-002271-41: Efficacy of Pioglitazone and Glimepiride Combination Therapy in Treating Subjects With Type 2 Diabetes Mellitus.

Completed
3
91
Europe
Pioglitazone and Glimepiride, ACTOS®, Glimepiride
Takeda
Diabetes Mellitus
12/08
12/08
ACCORD, NCT00000620: Action to Control Cardiovascular Risk in Diabetes

Completed
3
10251
US, Canada
Anti-hyperglycemic Agents, glimepiride (Amaryl), metformin (Glucophage), repaglinide (Gluconorm, Prandin), rosiglitazone (Avandia), pioglitazone (Actos), human regular insulin (Novolin ge Toronto), human NPH (Novolin N), human mixed (Novolin 70/30), human isophane (Novolin ge NPH), human 30/70 (Novolin ge 30/70), insulin aspart (NovoRapid, NovoLog), insulin detemir (Levemir), human regular insulin (Novolin R), insulin glargine (Lantus), Acarbose, Anti-hypertensive Agents, benazepril (Lotensin, Zestril, Altace), chlorthalidone (Thalitone), metoprolol (Toprol XL), diltiazem (Tiazac), plendil (Felodipine), terazosin (Hytrin), candesartan (Atacand), valsartan (Diovan), furosemide, reserpine, hydralazine, carvedilol (Coreg), triamterene / hydrochlorothiazide (Dyazide), metoprolol / hydrochlorothiazide(Lopressor HCT), benazepril / hydrochlorothiazide (Lotensin HCT), lisinopril / hydrochlorothiazide (Zestoretic), candesartan / hydrochlorothiazide (Atacand HCT), valsartan / hydrochlorothiazide (Diovan HCT), amlodipine / benazepril (Lotrel), Blinded fenofibrate or placebo plus simvastatin, fenofibrate (Tricor)
National Heart, Lung, and Blood Institute (NHLBI), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Aging (NIA), National Eye Institute (NEI), Centers for Disease Control and Prevention
Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Type 2, Diabetes Mellitus, Coronary Disease
06/09
12/12
NCT00655863 / 2007-000486-38: Efficacy of Alogliptin and With Pioglitazone in Patients With Type 2 Diabetes.

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Jan 2014 - Jan 2014: 
Checkmark P3 data
Jan 2012 - Jan 2012: P3 data
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Completed
3
71
Europe
Alogliptin and Pioglitazone, alogliptin, SYR110322, Actos, AD-4833, SYR-322, Alogliptin, Placebo
Takeda
Diabetes Mellitus
12/09
12/09
NCT01156597: Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes

Completed
3
30
US
pioglitazone, ACTOS
University of Miami, Takeda Pharmaceuticals North America, Inc.
Type 2 Diabetes Mellitus
09/10
09/10

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