CNS Disorders  >>  memantine  >>  Phase 2
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9 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
memantine / Generic mfg.
NCT02580305: SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study

Not Appicable Jul 2019 - Aug 2019 : Top-line efficacy results
Checkmark Data estimate
Oct 2018 - Oct 2018: Data estimate
Checkmark Completion of enrollment in P2a trial for Alzheimer's disease
Oct 2018 - Oct 2018: Completion of enrollment in P2a trial for Alzheimer's disease
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Completed
2a
564
US
SUVN-502, Masupirdine, Placebo, Donepezil, Namzaric, Memantine, Namenda XR®
Suven Life Sciences Limited
Alzheimer's Disease
11/19
11/19
Memantine-MS, NCT00638833 / 2006-003887-76: Memantine Therapy for Multiple Sclerosis

Terminated
2
20
Europe
Memantine, Ebixa, Placebo
Clinica Universidad de Navarra, Universidad de Navarra, H. Lundbeck A/S
Multiple Sclerosis
03/08
03/08
NCT01261741 / 2010-020737-50: Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems

Completed
2
299
Europe
Memantine, Placebo
Merz Pharmaceuticals GmbH
Memory Disorder, Retention Disorder, Cognitive, Subjective Cognitive Impairment, Memory, Concentration or Attention Problems
08/11
09/11
NCT01626391 / 2011-005292-17: Safety Study of TRx0237 in Patients Already Taking Medications for Mild and Moderate Alzheimer's Disease

Terminated
2
9
Europe
TRx0237, Placebo
TauRx Therapeutics Ltd
Alzheimer's Disease
03/13
03/13
MAyflOwer RoAD, NCT01677754 / 2012-000943-29: A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy

Completed
2
542
US, Canada, Europe, RoW
RO4602522, Placebo, Donepezil, Memantine, Rivastigmine, Galantamine
Hoffmann-La Roche
Alzheimer's Disease
06/15
06/15
NCT02246075: Study of the Safety of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Currently Receiving Memantine

Checkmark
Apr 2015 - Apr 2015: 
Withdrawn
2
0
US
EVP-6124, encenicline
FORUM Pharmaceuticals Inc, Quintiles, Inc.
Alzheimer's Disease, Dementia, Cognition
10/16
 
2017-004125-32: A randomised, double blind, placebo controlled trial to evaluate the safety, efficacy and pharmakokinetics of Pleconaril as an add on to AchEI/memantine for treatment of patients with Alzheimer’s disease

Ongoing
2
120
Europe
pleconaril, Capsule, hard
Apodemus Aktiebolag, Apodemus AB
Alzheimer's disease, Alzheimer's disease, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT03560245: A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine

Completed
2
108
US
Bryostatin, Placebo
Neurotrope Bioscience, Inc., Worldwide Clinical Trials
Alzheimer Disease
07/19
07/19
NCT04538066: Bryostatin Treatment of Moderately Severe Alzheimer's Disease

Completed
2
117
US
Bryostatin 1, Placebo
Neurotrope Bioscience, Inc., National Institutes of Health (NIH), National Institute on Aging (NIA)
Alzheimer Disease
11/22
11/22

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