propranolol / Generic mfg.  >>  Phase 4
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37 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
propranolol / Generic mfg.
ChiCTR-TRC-09000426: Randomized controlled trial of losartan\propranolol in treating portal hypertension

Completed
4
90
 
Oral losartan by 25mg/d of the initial dose, three days latter alternate to 50mg/d ;Oral propranolol by 20mg/d of initial dose; then, progressively increase 10mg/d, max dose 120mg/d or rest heart rate reduced to the 75% of fundamental rate, or no less than 55/min ;Placebo
Department 1 of Infectious Diseases, 302 Hospital of P.L.A; Level of the institution:, self-finance
portal hypertension
 
 
ChiCTR-TRC-11001577: Randomized controlled study of TIPS versus EBL plus propranolol for preventing variceal rebleeding in advanced cirrhotic patients combined with portal vein thrombosis

Completed
4
72
 
TIPS ;EBL+propranolol
West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self-financing
hepatic cirrhosis, esophageal variceal bleeding
 
 
2014-001380-13: PROPRANOLOL IN BURNT ADULT PATIENTS PROPANOLOL EN EL PACIENTE QUEMADO ADULTO

Ongoing
4
20
Europe
PROPRANOLOL, Tablet, SUMIAL
Abelardo Garcia De Lorenzo / Teresa Nuñez-Villaveiran, none
BURNT-INDUCED SINUSAL TACHYCARDIA TAQUICARDIA SINUSAL INDUCIDA POR LA QUEMADURA, BURNT-INDUCED SINUSAL TACHYCARDIA TAQUICARDIA SINUSAL INDUCIDA POR LA QUEMADURA, Diseases [C] - Injuries, poisonings, and occupational diseases [C21]
 
 
2013-004798-29`ACTRN12610000523000: A pill against fear: reducing fear by pharmacologically influencing memories. A clinical trial.

Ongoing
4
70
Europe
PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE
Cristina Cabral
Chronic low back pain
 
 
2016-002392-10: Reconsolidation interference versus retrieval interference as the basis for experimental amnesia in humans – The effect of drug state at memory retrieval

Ongoing
4
60
Europe
Propranolol, C07AA05, Tablet, Propranolol EG (Eurogenerics NV) - 40 mg
UZ Leuven, ERC
Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved. Our objective is to test wether the internal drug state induced by a single dose of propranolol (40 mg) is salient/potent enough to make retrieval of a conditioned fear memory reactivated before drug administration state-dependent., Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved., Psychiatry and Psychology [F] - Psychological processes [F02]
 
 
2016-000279-26: Role of propranolol in the treatment of migraine Rol van propranolol bij de behandeling van migraine

Ongoing
4
22
Europe
Oral solution, SYPROL® 50mg/5ml Oral Solution
Erasmus MC, Erasmus MC
Healthy Volunteers (Migraine) Gezonde vijwilligers (Migraine), Healthy volunteers (Migraine) Gezonde vrijwilligers (Migraine), Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR-IPR-17013197: A prospective, rater-blinded and self-controlled pilot study of the treatment of infantile hemangioma with oral propranolol versus combined with 0.5% topical timolol cream

Completed
4
40
 
oral propranolol alone ;combination of oral propranolol and topical timolol
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine; Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine, Science and Technology Commission of Shanghai Municipality (No.16ZR1419800)
Infantile hemangioma
 
 
NCT02924610: Brief Intervention to Reduce Fear

Recruiting
4
20
US
propranolol, inderal, placebo
Research Foundation for Mental Hygiene, Inc.
Social Anxiety Disorder
06/18
 
2018-001683-37: The RIME-IVF studyInvestigation of RIsk factors in out-of-hospital-cardiac-arrest patients, and MEdical treatment in unexplained cardiac arrests survivors

Ongoing
4
218
Europe
Propranolol R, C07AA05, Capsule, Propranolol retard
Rigshospitalet, Hjerteforeningen
Unexplained cardiac arrest patients after thorough investigations (Idiopathic ventricular fibrillation, IVF), Survivors of cardiac arrest, where cause of arrhythmia is not revealed during clinical examinations, Diseases [C] - Cardiovascular Diseases [C14]
 
 
ChiCTR-IPR-16009281: Investigation and prediction on resistance of infantile hemangioma in midanaphase of propranolol treatment

Not yet recruiting
4
40
 
local injection of propranolol ;termination of treatment
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, School of Medicine; Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, School of Medicine, National Natural Science Foundation of China (81601699)
Infantile hemangioma
 
 
2018-003409-25: Dose-dependent effects of propranolol on extinction learning and return of fear

Ongoing
4
144
Europe
Propranolol, C07AA05, Tablet, Propranolol EG (Eurogenerics NV) - 40 mg
KU Leuven, European Research Council
Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved. Our objective is to test whether propranolol administration has a dose-dependent effect on the facilitation of extinction learning and subsequent return of fear., Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved., Psychiatry and Psychology [F] - Psychological processes [F02]
 
 
ChiCTR-IPR-17012836: Randomized controlled trial of carvedilol and propranolol in the treatment of HVPG patients with cirrhosis and portal hypertension

Not yet recruiting
4
170
 
carvedilol 10mg bid ;propranolol 60mg bid
Drum Tower Hospital affiliated to Nanjing University Medicine School; Drum Tower Hospital affiliated to Nanjing University Medicine School, Self financing
portal hypertension and cirrhosis
 
 
2018-002829-33: A new treatment for smoking cessation. Een nieuwe behandeling voor stoppen met roken.

Not yet recruiting
4
30
Europe
Capsule, Propranolol Hcl
TNO, TNO
nicotine addiction nicotine verslaving, smoking roken, Psychiatry and Psychology [F] - Behaviours [F01]
 
 
ChiCTR1800016242: A single center, blank control and exploratory clinical study of propranolol hydrochloride in the treatment of central nervous system hemangioblastoma

Recruiting
4
20
 
Drug treatment ;Blank
Department of Neurosurgery of Huashan Hospital Affiliated to Fudan University; Huashan Hospital Affiliated to Fudan University, Self expense
Hemangioblastoma of the central nervous system
 
 
2020-000934-16: A new treatment for combat-related traumatic experiences.

Not yet recruiting
4
8
Europe
Tablet, Propranolol HCl
TNO, TNO
Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
2020-003563-26: A new treatment for traumatized healthcare workers.

Not yet recruiting
4
15
Europe
Tablet, Propranolol HCl
TNO, TNO
Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04]
 
 
2020-004059-34: Activation of human brown adipose tissue with the use of salbutamol

Ongoing
4
10
Europe
Concentrate for solution for injection/infusion, Tablet, Ventolin infuus/injectie, Propranolol HCl Accord
Leiden University Medical Center, Diabetes Fonds, Dutch Heart Foundation
Obesity, overweight, lipid- and glucose metabolism, In this study we will investigate whether we can activate energy-burning brown adipose tissue to combat overweight, obesity and associated cardio metabolic diseases, such as diabetes., Body processes [G] - Metabolic Phenomena [G03]
 
 
NCT04683146: Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate ( Sorbectol )

Not yet recruiting
4
24
NA
Hand antisepsis with Propanolol- 1 60%., Hand antisepsis with a solution of alcohol, chlorhexidine digluconate and potassium sorbate.
Centro Ortopedico y Quirurgico del Pie
Antisepsis
03/21
06/21
NCT05195996: Beta Blocker Effects in Traumatic Brain Injury

Completed
4
40
RoW
Propranolol, Saline
Menoufia University
Trauma, Brain
03/22
05/22
NCT04767061: Impact of Beta-blockers on Physical Function in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, The New York Community Trust
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/22
04/23
NCT05106179: The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Enrolling by invitation
4
1000
RoW
Atenolol Pill, Propranolol Pill
Center for Vascular Pathology, Moscow
Spinal Tumor, Spinal Hemangioma, Beta Blocker Toxicity
12/22
12/23
NCT04757584: Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, National Institute on Aging (NIA)
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/23
04/23
ChiCTR2000033415: Effect of different discontinuation regimens of propranolol on relapse of infantile hemangiomas: a prospective randomized controlled study

Not yet recruiting
4
536
 
discontinued propranolol directly from 1 month after the hemangioma reaches its maximum regression ;discontinued propranolol directly from 3 months after the hemangioma reaches its maximum regression ;discontinued propranolol gradually within 4 weeks from 1 month after the hemangioma reaches its maximum regression ;discontinued propranolol gradually within 4 weeks from 3 months after the hemangioma reaches its maximum regression
Shandong Provincial Hospital; Shandong Provincial Hospital, Foundation of Taishan Scholar
infantile hemangioma
 
 
NCT05479123: Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas

Recruiting
4
174
US
Propranolol three times a day, Propranolol twice a day, Timolol
The University of Texas Health Science Center, Houston
Infantile Hemangioma
03/25
07/25
CAMTREA, NCT04989413: Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg vs Placebo as Adjuvant Treatment in Chronic Migraine -

Recruiting
4
110
RoW
Placebo oral drops, Cannabidiol + Cannabigerol + Tetrahydrocannabinol 133/66/4mg
Hospital Israelita Albert Einstein, Industria Farmacêutica Health Meds
Chronic Migraine, Headache, Overuse Headache Medication
10/23
04/24
P-HCC, NCT01970748: Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices

Recruiting
4
200
RoW
Propranolol, Inderal, Cardolol, Esophageal variceal ligation, EVL
Taipei Veterans General Hospital, Taiwan
Bleeding Esophageal Varices, Hepatocellular Carcinoma
12/23
12/25
NCT06149507: Effect of Acetaminophen Versus Ibuprofen in Treating Recurrent Apthous Ulcers in Pediatric Celiac Disease

Not yet recruiting
4
12
NA
Acetaminophen, Paracetamol, Ibuprofen, Brufin
Cairo University
Celiac Disease in Children
09/24
12/24
NCT06263452: Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

Recruiting
4
120
US
Propranolol, Inderal, Propranolol hydrochloride, Placebo, Sugar pill
University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI), University of California, Los Angeles, Dartmouth College
Cardiovascular Disease
05/26
05/26
PRL-SRL-IHHE, NCT04406870: Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)

Not yet recruiting
4
36
RoW
Sirolimus Oral Product, TORISEL, rapamycin, propranolol, xin de an (chinese name means making me comfortable)
Shanghai Children's Medical Center
Hemangioendothelioma of Liver
06/24
06/25
STARS, NCT05997732: Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences

Recruiting
4
30
Canada
Phenylephrine Hydrochloride, Isoproterenol Hydrochloride, Norepinephrine Bitartrate, Propranolol Hydrochloride, Phentolamine Mesylate
University of Alberta
Vasoconstriction, Vasodilation
09/24
09/24
BBTBBT, NCT04508244: Beta Blocker Use In Traumatic Brain Injury Based On The High-Sensitive Troponin T Status

Recruiting
4
771
RoW
Placebo, Propranolol, inderal
Hamad Medical Corporation
Trauma, Brain Injuries, Stress Reaction, Beta Blockers, Troponin
12/24
12/24
ChiCTR2300067478: Phase IV clinical study on the safety, efficacy and population pharmacokinetics of propranolol hydrochloride oral solution in the treatment of infantile hemangioma

Not yet recruiting
4
80
 
propranolol hydrochloride oral solution, 2mg/kg*d, twice a day
Beijing Children's Hospital, Capital Medical University; Wuhan Conform Pharmaceutical Co., Ltd., self-financed
infantile hemangioma
 
 
ChiCTR2200064613: Combined oral propranolol with intralesional injection of diprospan in treatment of small and localized infantile hemangiomas with high risks of severe skin sequela: a randomized, single-center controlled trial

Not yet recruiting
4
120
 
Oral propranolol liquid daily, 2mg/kg*d, twice a day, for at least six months until complete remission ;Monthly injections of compound betamethasone solution, no more than 1ml per injection and no more than 6 injections
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Latitudinal project
Infantile hemangioma
 
 
NCT05853627: Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery

Recruiting
4
80
US
Memory reactivation procedures, Propranolol
Massachusetts General Hospital
Stress Disorders, Post-Traumatic
06/25
06/25
NCT05587361: Beta-Adrenergic Modulation of Drug Cue Reactivity

Not yet recruiting
4
80
US
Propranolol, Nicotine Patch, Placebo Propranolol, Placebo Patch
University of Oklahoma, Oklahoma State University Center for Health Sciences, Duke University, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH)
Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking
03/25
03/25
NCT01298271: A Randomized Trial of GVS Alone vs. Propranolol

Recruiting
4
120
RoW
propranolol, Inderal, Cardolol
Taipei Veterans General Hospital, Taiwan
Bleeding Gastric Varices, Liver Cirrhosis
12/25
12/25
NCT04580134: CLOZAPINE Response in Biotype-1

Recruiting
4
524
US
clozapine, Clozaril, risperidone, Risperdal
University of Texas Southwestern Medical Center, National Institute of Mental Health (NIMH), Beth Israel Deaconess Medical Center, Hartford Hospital, University of Georgia, University of Chicago
Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder
12/25
03/26

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