propranolol / Generic mfg. |
ChiCTR-TRC-09000426: Randomized controlled trial of losartan\propranolol in treating portal hypertension |
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| Completed | 4 | 90 | | Oral losartan by 25mg/d of the initial dose, three days latter alternate to 50mg/d ;Oral propranolol by 20mg/d of initial dose; then, progressively increase 10mg/d, max dose 120mg/d or rest heart rate reduced to the 75% of fundamental rate, or no less than 55/min ;Placebo | Department 1 of Infectious Diseases, 302 Hospital of P.L.A; Level of the institution:, self-finance | portal hypertension | | | | |
ChiCTR-TRC-11001577: Randomized controlled study of TIPS versus EBL plus propranolol for preventing variceal rebleeding in advanced cirrhotic patients combined with portal vein thrombosis |
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| Completed | 4 | 72 | | TIPS ;EBL+propranolol | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self-financing | hepatic cirrhosis, esophageal variceal bleeding | | | | |
2014-001380-13: PROPRANOLOL IN BURNT ADULT PATIENTS PROPANOLOL EN EL PACIENTE QUEMADO ADULTO |
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| Ongoing | 4 | 20 | Europe | PROPRANOLOL, Tablet, SUMIAL | Abelardo Garcia De Lorenzo / Teresa Nuñez-Villaveiran, none | BURNT-INDUCED SINUSAL TACHYCARDIA TAQUICARDIA SINUSAL INDUCIDA POR LA QUEMADURA, BURNT-INDUCED SINUSAL TACHYCARDIA TAQUICARDIA SINUSAL INDUCIDA POR LA QUEMADURA, Diseases [C] - Injuries, poisonings, and occupational diseases [C21] | | | | |
| Ongoing | 4 | 70 | Europe | PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE | Cristina Cabral | Chronic low back pain | | | | |
2016-002392-10: Reconsolidation interference versus retrieval interference as the basis for experimental amnesia in humans – The effect of drug state at memory retrieval |
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| Ongoing | 4 | 60 | Europe | Propranolol, C07AA05, Tablet, Propranolol EG (Eurogenerics NV) - 40 mg | UZ Leuven, ERC | Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved. Our objective is to test wether the internal drug state induced by a single dose of propranolol (40 mg) is salient/potent enough to make retrieval of a conditioned fear memory reactivated before drug administration state-dependent., Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved., Psychiatry and Psychology [F] - Psychological processes [F02] | | | | |
2016-000279-26: Role of propranolol in the treatment of migraine Rol van propranolol bij de behandeling van migraine |
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| Ongoing | 4 | 22 | Europe | Oral solution, SYPROL® 50mg/5ml Oral Solution | Erasmus MC, Erasmus MC | Healthy Volunteers (Migraine) Gezonde vijwilligers (Migraine), Healthy volunteers (Migraine) Gezonde vrijwilligers (Migraine), Diseases [C] - Nervous System Diseases [C10] | | | | |
ChiCTR-IPR-17013197: A prospective, rater-blinded and self-controlled pilot study of the treatment of infantile hemangioma with oral propranolol versus combined with 0.5% topical timolol cream |
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| Completed | 4 | 40 | | oral propranolol alone ;combination of oral propranolol and topical timolol | Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine; Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine, Science and Technology Commission of Shanghai Municipality (No.16ZR1419800) | Infantile hemangioma | | | | |
| Recruiting | 4 | 20 | US | propranolol, inderal, placebo | Research Foundation for Mental Hygiene, Inc. | Social Anxiety Disorder | 06/18 | | | |
2018-001683-37: The RIME-IVF studyInvestigation of RIsk factors in out-of-hospital-cardiac-arrest patients, and MEdical treatment in unexplained cardiac arrests survivors |
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| Ongoing | 4 | 218 | Europe | Propranolol R, C07AA05, Capsule, Propranolol retard | Rigshospitalet, Hjerteforeningen | Unexplained cardiac arrest patients after thorough investigations (Idiopathic ventricular fibrillation, IVF), Survivors of cardiac arrest, where cause of arrhythmia is not revealed during clinical examinations, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-IPR-16009281: Investigation and prediction on resistance of infantile hemangioma in midanaphase of propranolol treatment |
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| Not yet recruiting | 4 | 40 | | local injection of propranolol ;termination of treatment | Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, School of Medicine; Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, School of Medicine, National Natural Science Foundation of China (81601699) | Infantile hemangioma | | | | |
2018-003409-25: Dose-dependent effects of propranolol on extinction learning and return of fear |
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| Ongoing | 4 | 144 | Europe | Propranolol, C07AA05, Tablet, Propranolol EG (Eurogenerics NV) - 40 mg | KU Leuven, European Research Council | Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved. Our objective is to test whether propranolol administration has a dose-dependent effect on the facilitation of extinction learning and subsequent return of fear., Experimental study with healthy participants recruited from the general population; no vulnerable individuals or clinical groups will be involved., Psychiatry and Psychology [F] - Psychological processes [F02] | | | | |
ChiCTR-IPR-17012836: Randomized controlled trial of carvedilol and propranolol in the treatment of HVPG patients with cirrhosis and portal hypertension |
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| Not yet recruiting | 4 | 170 | | carvedilol 10mg bid ;propranolol 60mg bid | Drum Tower Hospital affiliated to Nanjing University Medicine School; Drum Tower Hospital affiliated to Nanjing University Medicine School, Self financing | portal hypertension and cirrhosis | | | | |
2018-002829-33: A new treatment for smoking cessation. Een nieuwe behandeling voor stoppen met roken. |
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| Not yet recruiting | 4 | 30 | Europe | Capsule, Propranolol Hcl | TNO, TNO | nicotine addiction nicotine verslaving, smoking roken, Psychiatry and Psychology [F] - Behaviours [F01] | | | | |
ChiCTR1800016242: A single center, blank control and exploratory clinical study of propranolol hydrochloride in the treatment of central nervous system hemangioblastoma |
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| Recruiting | 4 | 20 | | Drug treatment ;Blank | Department of Neurosurgery of Huashan Hospital Affiliated to Fudan University; Huashan Hospital Affiliated to Fudan University, Self expense | Hemangioblastoma of the central nervous system | | | | |
| Not yet recruiting | 4 | 8 | Europe | Tablet, Propranolol HCl | TNO, TNO | Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 15 | Europe | Tablet, Propranolol HCl | TNO, TNO | Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2020-004059-34: Activation of human brown adipose tissue with the use of salbutamol |
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| Ongoing | 4 | 10 | Europe | Concentrate for solution for injection/infusion, Tablet, Ventolin infuus/injectie, Propranolol HCl Accord | Leiden University Medical Center, Diabetes Fonds, Dutch Heart Foundation | Obesity, overweight, lipid- and glucose metabolism, In this study we will investigate whether we can activate energy-burning brown adipose tissue to combat overweight, obesity and associated cardio metabolic diseases, such as diabetes., Body processes [G] - Metabolic Phenomena [G03] | | | | |
NCT04683146: Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate ( Sorbectol ) |
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| Not yet recruiting | 4 | 24 | NA | Hand antisepsis with Propanolol- 1 60%., Hand antisepsis with a solution of alcohol, chlorhexidine digluconate and potassium sorbate. | Centro Ortopedico y Quirurgico del Pie | Antisepsis | 03/21 | 06/21 | | |
| Completed | 4 | 40 | RoW | Propranolol, Saline | Menoufia University | Trauma, Brain | 03/22 | 05/22 | | |
NCT04767061: Impact of Beta-blockers on Physical Function in HFpEF |
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| Completed | 4 | 9 | US | Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate | Weill Medical College of Cornell University, The New York Community Trust | Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease | 04/22 | 04/23 | | |
NCT05106179: The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma |
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| Enrolling by invitation | 4 | 1000 | RoW | Atenolol Pill, Propranolol Pill | Center for Vascular Pathology, Moscow | Spinal Tumor, Spinal Hemangioma, Beta Blocker Toxicity | 12/22 | 12/23 | | |
NCT04757584: Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF |
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| Completed | 4 | 9 | US | Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate | Weill Medical College of Cornell University, National Institute on Aging (NIA) | Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease | 04/23 | 04/23 | | |
ChiCTR2000033415: Effect of different discontinuation regimens of propranolol on relapse of infantile hemangiomas: a prospective randomized controlled study |
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| Not yet recruiting | 4 | 536 | | discontinued propranolol directly from 1 month after the hemangioma reaches its maximum regression ;discontinued propranolol directly from 3 months after the hemangioma reaches its maximum regression ;discontinued propranolol gradually within 4 weeks from 1 month after the hemangioma reaches its maximum regression ;discontinued propranolol gradually within 4 weeks from 3 months after the hemangioma reaches its maximum regression | Shandong Provincial Hospital; Shandong Provincial Hospital, Foundation of Taishan Scholar | infantile hemangioma | | | | |
NCT05479123: Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas |
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| Recruiting | 4 | 174 | US | Propranolol three times a day, Propranolol twice a day, Timolol | The University of Texas Health Science Center, Houston | Infantile Hemangioma | 03/25 | 07/25 | | |
CAMTREA, NCT04989413: Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg vs Placebo as Adjuvant Treatment in Chronic Migraine - |
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| Recruiting | 4 | 110 | RoW | Placebo oral drops, Cannabidiol + Cannabigerol + Tetrahydrocannabinol 133/66/4mg | Hospital Israelita Albert Einstein, Industria Farmacêutica Health Meds | Chronic Migraine, Headache, Overuse Headache Medication | 10/23 | 04/24 | | |
P-HCC, NCT01970748: Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices |
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| Recruiting | 4 | 200 | RoW | Propranolol, Inderal, Cardolol, Esophageal variceal ligation, EVL | Taipei Veterans General Hospital, Taiwan | Bleeding Esophageal Varices, Hepatocellular Carcinoma | 12/23 | 12/25 | | |
NCT06149507: Effect of Acetaminophen Versus Ibuprofen in Treating Recurrent Apthous Ulcers in Pediatric Celiac Disease |
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| Not yet recruiting | 4 | 12 | NA | Acetaminophen, Paracetamol, Ibuprofen, Brufin | Cairo University | Celiac Disease in Children | 09/24 | 12/24 | | |
NCT06263452: Beta-Blocker Influences on Inflammatory and Neural Responses to Stress |
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| Recruiting | 4 | 120 | US | Propranolol, Inderal, Propranolol hydrochloride, Placebo, Sugar pill | University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI), University of California, Los Angeles, Dartmouth College | Cardiovascular Disease | 05/26 | 05/26 | | |
| Not yet recruiting | 4 | 36 | RoW | Sirolimus Oral Product, TORISEL, rapamycin, propranolol, xin de an (chinese name means making me comfortable) | Shanghai Children's Medical Center | Hemangioendothelioma of Liver | 06/24 | 06/25 | | |
STARS, NCT05997732: Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences |
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| Recruiting | 4 | 30 | Canada | Phenylephrine Hydrochloride, Isoproterenol Hydrochloride, Norepinephrine Bitartrate, Propranolol Hydrochloride, Phentolamine Mesylate | University of Alberta | Vasoconstriction, Vasodilation | 09/24 | 09/24 | | |
BBTBBT, NCT04508244: Beta Blocker Use In Traumatic Brain Injury Based On The High-Sensitive Troponin T Status |
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| Recruiting | 4 | 771 | RoW | Placebo, Propranolol, inderal | Hamad Medical Corporation | Trauma, Brain Injuries, Stress Reaction, Beta Blockers, Troponin | 12/24 | 12/24 | | |
ChiCTR2300067478: Phase IV clinical study on the safety, efficacy and population pharmacokinetics of propranolol hydrochloride oral solution in the treatment of infantile hemangioma |
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| Not yet recruiting | 4 | 80 | | propranolol hydrochloride oral solution, 2mg/kg*d, twice a day | Beijing Children's Hospital, Capital Medical University; Wuhan Conform Pharmaceutical Co., Ltd., self-financed | infantile hemangioma | | | | |
ChiCTR2200064613: Combined oral propranolol with intralesional injection of diprospan in treatment of small and localized infantile hemangiomas with high risks of severe skin sequela: a randomized, single-center controlled trial |
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| Not yet recruiting | 4 | 120 | | Oral propranolol liquid daily, 2mg/kg*d, twice a day, for at least six months until complete remission ;Monthly injections of compound betamethasone solution, no more than 1ml per injection and no more than 6 injections | Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Latitudinal project | Infantile hemangioma | | | | |
NCT05853627: Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery |
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| Recruiting | 4 | 80 | US | Memory reactivation procedures, Propranolol | Massachusetts General Hospital | Stress Disorders, Post-Traumatic | 06/25 | 06/25 | | |
NCT05587361: Beta-Adrenergic Modulation of Drug Cue Reactivity |
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| Not yet recruiting | 4 | 80 | US | Propranolol, Nicotine Patch, Placebo Propranolol, Placebo Patch | University of Oklahoma, Oklahoma State University Center for Health Sciences, Duke University, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) | Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking | 03/25 | 03/25 | | |
NCT01298271: A Randomized Trial of GVS Alone vs. Propranolol |
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| Recruiting | 4 | 120 | RoW | propranolol, Inderal, Cardolol | Taipei Veterans General Hospital, Taiwan | Bleeding Gastric Varices, Liver Cirrhosis | 12/25 | 12/25 | | |
| Recruiting | 4 | 524 | US | clozapine, Clozaril, risperidone, Risperdal | University of Texas Southwestern Medical Center, National Institute of Mental Health (NIMH), Beth Israel Deaconess Medical Center, Hartford Hospital, University of Georgia, University of Chicago | Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder | 12/25 | 03/26 | | |