| propranolol / Generic mfg. |
ACTRN12612001026819: Bacterial translocation and amelioration of liver cell damage in response to treatment with propranolol, with or without rifaximin, in patients with cirrhosis and portal hypertension |
|
|
| Not yet recruiting | 2 | 50 | | | Professor Stephen Riordan, Professor Stephen Riordan | Cirrhosis and portal hypertension | | | | |
| Ongoing | 2 | 10 | Europe | propranololo sciroppo prodotto galenico, Syrup | AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI | congenital hemangiomas | | | | |
| Ongoing | 2 | 20 | Europe | propranolol cream 1%, Cream | AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI | pyogenic granulomas | | | | |
2012-001020-35: A clinical phase II trial to compare the efficacy of Bevacizumab monotherapy with standard chemotherapy (dacarbazine) in metastatic melanoma. En fase 2 studie for å sammenligne effekten av Bevacizumab monoterapi med standard kjemoterapi (dacarbazine) ved malignt melanom med metastaser. |
|
|
| Ongoing | 2 | 120 | Europe | Bevacizumab, Dacarbazine, Inderal, Renitec, 091652, Avastin (Bevacizumab), Dacarbazine, Inderal (Propranolol), Renitec (Enalapril), Avastin (Bevacizumab), Dacarbazine, Inderal (Propranolol), Renitec (Enalapril) | Helse Bergen HF, Haukeland University Hospital, The Norwegian Cancer Association | Previously treated or untreated histologically confirmed metastatic and unresectable melanoma with radiological (RECIST), clinical or biochemical progressive disease. | | | | |
2014-003970-18: clinical trial to assess efficacy and safety of once daily 80 mg propranolol therapy to overall survival for cutaneous melanoma studio sperimentale per verificare l'efficacia e la sicurezza della terapia con propranololo 80 mg una volta al giorno nel migliorare il decorso del melanoma cutaneo |
|
|
| Ongoing | 2 | 23 | Europe | Prolonged-release tablet, INDERAL - 80 MG CAPSULE RIGIDE A RILASCIO PROLUNGATO 28 CAPSULE | AZIENDA SANITARIA DI FIRENZE, Istituto Toscano Tumori | melanoma melanoma, tumore cutaneo, Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
2017-003595-30: Clinical study to evaluate the efficacy of propranolol in familial Cerebral Cavernous Malformation Studio per valutare l'efficacia del propranololo nel trattamento dei pazienti con CCM famigliare |
|
|
| Ongoing | 2 | 60 | Europe | Propranololo, [C07AA05], Tablet, INDERAL - 40 MG COMPRESSE 30 COMPRESSE | IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI, AIFA - Italian Medicines Agency | Cerebral Cavernous Malformation (CCM) Malformazione Cavernosa Cerebrale (CCM), The term refers to a familial decease characterized by mulberry-shaped abnormal blood vessels in the brain or spine. Una patologia familiare, caratterizzata da malformazioni vascolari (angiomi) nel cervello o nel midollo spinale., Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT04580342: Ivabradine Versus Propranolol for Induced Hypotension in Endoscopic Sinus Surgery |
|
|
| Recruiting | 2 | 60 | RoW | oral Ivabradine, oral Propranolol | Ahmed talaat ahmed aly | Hypotension | 01/21 | 01/21 | | |
NCT03152786: Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery |
|
|
| Terminated | 2 | 46 | US | Laboratory Biomarker Analysis, Propranolol Hydrochloride, Inderal, Innopran XL, Questionnaire Administration, Survey Administration | Wake Forest University Health Sciences, National Cancer Institute (NCI) | Prostate Carcinoma | 06/21 | 02/23 | | |
NCT04684667: ''Efficacy of Propranolol in the Treatment of Infantile Hemangioma" |
|
|
| Not yet recruiting | 2 | 100 | RoW | Propranolol Therapy for Infantile Hemangioma, Propranolol Treatment for Infantile Hemangioma | Assiut University | Infantile Hemangioma | 12/21 | 12/21 | | |
2021-003788-82: A phase 2 on propranolol in combination with pembrolizumab in advanced Angiosarcoma and Undifferentiated Pleomorphic Sarcoma Et fase 2 forsøg af propanolol i kombination med pembrolizumab til patienter med fremskreden angiosarkom eller udifferentieret pleomorf sarkom. |
|
|
| Not yet recruiting | 2 | 80 | Europe | Film-coated tablet, Powder for concentrate for solution for infusion, Concentrate for solution for infusion, Keytruda | Department of Oncology, Herlev & Gentofte Hospital, Nordic Cancer Union | Advanced Angiosarcoma and Undifferentiated Pleomorphic Sarcoma, Two types of advanced soft tissue sarcoma (Angiosarcoma and Undifferentiated Pleomorphic Sarcoma ), Diseases [C] - Cancer [C04] | | | | |
NCT03152175: Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators |
|
|
| Recruiting | 2 | 64 | Canada | Propranolol Hydrochloride, Teva-propranolol, Placebo | Douglas Mental Health University Institute, Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail | Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders, Adjustment Disorders, Acute Stress Disorder | 03/22 | 03/23 | | |
2022-001184-28: PeP-RALP: A randomized, double-blind, placebo controlled feasibility study on perioperative use of propranolol during robotic assisted laparoscopic prostatectomy (RALP) in participants with intermediate to high-risk prostate cancer. |
|
|
| Not yet recruiting | 2 | 40 | Europe | Propranolol | Oslo University Hospital, Fondstiftelsen ved Oslo Universitetssykehus, Holes legat til fremme av kreftforskning i Norge, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital | Prostate Cancer, Prostate Cancer, Diseases [C] - Cancer [C04] | | | | |
ChiCTR2100047864: A clinical study of carrelizumab and apatinib mesylate combined with propranolol in the treatment of advanced cholangiocarcinoma |
|
|
| Not yet recruiting | 2 | 30 | | Patients receiving Carrelizumab 200mg QD+ apatinib mesylate tablets 250mgQD+ propranolol 40mg BID for 3 weeks | Hunan Provincial Tumor Hospital; Hunan Provincial Tumor Hospital, Jiangsu Hengrui Pharmaceutical Co. Ltd | Cholangiocarcinoma | | | | |
NCT06158230: Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis. |
|
|
| Active, not recruiting | 2 | 140 | RoW | Pizotifen, Amitriptyline-propranolol | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Migraine | 11/23 | 01/24 | | |
NCT04493489: Propranolol Adjuvant Treatment of Bladder Cancer |
|
|
| Not yet recruiting | 2 | 242 | NA | Propranolol Hydrochloride, BCG | Central South University | Bladder Cancer | 09/23 | 09/24 | | |
2019-002947-41: Propranolol as treatment of patients with angiosarcoma before their standard therapy. Propranolol als behandeling van patiënten met angiosarcoom voorafgaand aan hun standaard behandeling. |
|
|
| Not yet recruiting | 2 | 14 | Europe | propranolol, Tablet, propranolol | Netherlands Cancer Institute- Antoni van Leeuwenhoek, Netherlands Cancer Institute | Angiosarcoma angiosarcoom, cancer arising from the inner layer of the blood or lymphatic vessels kanker dat uit de binnenste laag van de bloed- of lymfevaten ontstaat, Diseases [C] - Cancer [C04] | | | | |
| Completed | 2 | 40 | Europe | Propranolol, Pranolol | Oslo University Hospital, Ivar, Ragna og Morten Holes legat til fremme av kreftforskningen i Norge, Fondsstiftelsen ved Oslo Universitetssykehus | Prostate Cancer | 11/23 | 01/24 | | |
| Completed | 2 | 14 | Europe | Propranolol | The Netherlands Cancer Institute, Anticancer Fund, Belgium | Angiosarcoma | 10/23 | 10/23 | | |
NCT04047355: Propranolol for Challenging Behaviors in Autism |
|
|
| Active, not recruiting | 2 | 6 | US | Propranolol, Inderal | Rutgers, The State University of New Jersey, New Jersey Governor's Council for Medical Research and Treatment of Autism, New York State Institute for Basic Research | Autism Spectrum Disorder, Developmental Disability, Aggression, Self-Injurious Behavior, Challenging Behavior | 12/24 | 12/24 | | |
| Completed | 2 | 18 | Europe | metronomic therapy, Dociton, Celebrex, Endoxan, Lastet, Vinblastinsulfat Teva | University of Cologne | Recurrent Neuroblastoma | 06/23 | 06/23 | | |
NCT04982211: Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma |
|
|
| Not yet recruiting | 2 | 150 | Canada | Propranolol, Teva propranolol, Placebo, Placebo capsules | Douglas Mental Health University Institute, Canadian Institutes of Health Research (CIHR) | Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder, Acute Stress Disorder, Adjustment Disorders | 12/23 | 12/24 | | |
NCT04848519: Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma |
|
|
| Recruiting | 2 | 24 | US | Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Propranolol Hydrochloride, Inderal, Nivolumab, Avelumab | Emory University, National Cancer Institute (NCI) | Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma, Locally Advanced Urethral Urothelial Carcinoma, Locally Advanced Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma, Metastatic Ureter Urothelial Carcinoma, Metastatic Urethral Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Stage IV Bladder Cancer AJCC v8, Stage IV Renal Pelvis Cancer AJCC v8, Stage IV Ureter Cancer AJCC v8, Stage IV Urethral Cancer AJCC v8 | 01/26 | 01/27 | | |
NCT01950520: Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate |
|
|
| Completed | 2 | 80 | US | Propranolol, Pindolol, Dantrolene, Magnesium Sulfate, Caffeine, Qysmia, Topiramate, Phentermine, Naltrexone, Mirabegron 50mg, Mirabegron 200mg, Placebo Cohort 1, Placebo Cohort 2, Placebo for Mirabegron | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Healthy Volunteers | 12/22 | 06/24 | | |
NCT05173012: Study to Evaluate SAGE-324 in Participants With Essential Tremor |
|
|
| Completed | 2 | 147 | US | SAGE-324, SAGE-324 Matched Placebo | Sage Therapeutics, Biogen | Essential Tremor | 05/24 | 05/24 | | |
IMPULS, NCT06145074: Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC. |
|
|
| Recruiting | 2 | 30 | Europe | Propranolol, Inderal, Propal, Placebo, Inactive drug | Zealand University Hospital, Rigshospitalet, Denmark | Pancreatic Cancer, Surgery | 12/26 | 12/35 | | |
NCT05561751: Ph2, Study to Assess the Safety and Efficacy of GPC 100 and Propranolol With and Without G-CSF for the Mobilization of Stem Cells in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant |
|
|
| Recruiting | 2 | 40 | US | GPC-100, Propranolol, G-CSF | GPCR Therapeutics, Inc. | Multiple Myeloma | 03/25 | 06/25 | | |
NCT05375240: Propranolol on Post Stroke Immune Status and Infection |
|
|
| Not yet recruiting | 2 | 45 | RoW | Propranolol, Ceftriaxone | Tianjin Medical University General Hospital | Stroke, Cerebrovascular Disorders, Ischemic Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases, Propranolol, Beta Blocker, Molecular Mechanisms of Pharmacological Action, Immunologic Factors, Physiological Effects of Drugs | 06/24 | 06/24 | | |
| Recruiting | 2 | 168 | RoW | Propranolol Hydrochloride, control group | Beijing Tiantan Hospital | Stroke, Vascular Accident, Intracranial Hemorrhages, Intracerebral Hemorrhage, Hemorrhagic Stroke, Stroke, Acute | 07/24 | 07/25 | | |
| Recruiting | 2 | 276 | Europe, RoW | Propranolol, Placebo | University of Zurich, Ankara University, University Hospital Tuebingen | Retinopathy of Prematurity | 12/25 | 07/26 | | |
PTSD-FMS, NCT04950426: Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome |
|
|
| Recruiting | 2 | 25 | Europe | Propranolol | Centre Hospitalier Henri Laborit | Fibromyalgia Syndrome, Posttraumatic Stress Disorder | 08/24 | 08/24 | | |
NCT05085782: Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain |
|
|
| Recruiting | 2 | 48 | Canada | Propranolol Hydrochloride, Experimental group, Placebo, Control group, Reactivation procedure, Pain neuroscience education | Université de Sherbrooke | Chronic Low-back Pain, Fibromyalgia | 09/24 | 09/25 | | |
NCT06445166: Propranolol for the Treatment of Kaposi Sarcoma in Adults |
|
|
| Not yet recruiting | 2 | 25 | US | Propranolol Hydrochloride | Washington University School of Medicine | Kaposi Sarcoma | 03/27 | 09/27 | | |
NCT04186286: Crossover Study of Propranolol vs Ivabradine in POTS |
|
|
| Recruiting | 2 | 20 | Canada | Ivabradine 4-week course, Lancora, Propranolol 4-week course, Inderal, Placebo 4-week course | University of Calgary, Dysautonomia International | Postural Tachycardia Syndrome | 12/25 | 12/26 | | |
NCT05692271: Testing a Novel Therapeutic Strategy for Comorbid Post-Traumatic Stress Disorder and Alcohol Use Disorder |
|
|
| Recruiting | 2 | 48 | Canada | Propranolol, Placebo | Centre for Addiction and Mental Health | Stress Disorders, Post-Traumatic, Alcohol Use Disorder | 02/25 | 02/25 | | |
PROPRADO, NCT04921982: Efficacy of Traumatic Memory Modification Using Memory Reconsolidation and Propranolol Among Adolescents With PTSD |
|
|
| Not yet recruiting | 2 | 74 | Europe | Propranolol, Placebo | Rennes University Hospital | Post Traumatic Stress Disorder | 03/25 | 06/26 | | |
NCT05451043: Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED) |
|
|
| Recruiting | 2 | 62 | Canada | Durvalumab, Imfinzi, Gemcitabine, Gemzar, Nab paclitaxel, Abraxane, Tremelimumab, Propranolol, Cisplatin | AHS Cancer Control Alberta | Pancreatic Cancer, Hepatocellular Cancer, Biliary Tract Cancer, Cholangiocarcinoma | 10/25 | 10/28 | | |
NCT05651594: Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma |
|
|
| Recruiting | 2 | 40 | US | Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Fluorouracil, 5 Fluorouracil, 5 Fluorouracilum, 5 FU, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-Fu, 5FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Leucovorin, Folinic acid, Oxaliplatin, 1-OHP, Ai Heng, Aiheng, Dacotin, Dacplat, Diaminocyclohexane Oxalatoplatinum, Eloxatin, Eloxatine, JM-83, Oxalatoplatin, Oxalatoplatinum, RP 54780, RP-54780, SR-96669, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Propranolol Hydrochloride, Inderal, Innopran XL, Questionnaire Administration | Roswell Park Cancer Institute, United States Department of Defense | Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8, Locally Advanced Esophageal Adenocarcinoma, Locally Advanced Gastroesophageal Junction Adenocarcinoma, Metastatic Esophageal Adenocarcinoma, Metastatic Gastroesophageal Junction Adenocarcinoma, Unresectable Esophageal Adenocarcinoma, Unresectable Gastroesophageal Junction Adenocarcinoma | 03/26 | 03/26 | | |
NCT04682158: Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma |
|
|
| Recruiting | 2 | 106 | US | Carboplatin, (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2--)-O,O'']platinum, Blastocarb, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplatin, Ribocarbo, 3 Dimensional Conformal Radiation Therapy, 3D-CRT, Radiation, Propranolol, 2-Propanol-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy) Hydrochloride, 318-98-9, Inderal, Innopran XL, Intensity Modulated Radiation Therapy, IMRT, Paclitaxel, 33069-62-4, 5Beta,20-epoxy-1,2alpha, Anzatax, Bristaxol, Praxel, Taxol | Roswell Park Cancer Institute | Esophageal Adenocarcinoma | 04/27 | 04/27 | | |
| Not yet recruiting | 2 | 25 | RoW | Propranolol | AIDS Malignancy Consortium, National Cancer Institute (NCI) | Kaposi Sarcoma | 08/28 | 08/29 | | |
NCT05741164: Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer |
|
|
| Not yet recruiting | 2 | 25 | US | Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Propranolol, 1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol, Questionnaire Administration | Roswell Park Cancer Institute | Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma, Refractory Triple-Negative Breast Carcinoma, Unresectable Triple-Negative Breast Carcinoma | 12/26 | 12/27 | | |
| Recruiting | 2 | 80 | Europe | Propranolol, Betablocker, Pembrolizumab, anti PD-1 | Niels Junker, Aarhus University Hospital, Oslo University Hospital, Karolinska University Hospital | Soft Tissue Sarcoma Adult, Angiosarcoma, Undifferentiated Pleomorphic Sarcoma | 01/28 | 12/28 | | |
NCT03633747: Efficacy Evaluation of Propranolol Treatment of Hepatic Hemangioma |
|
|
| Recruiting | 1/2 | 25 | RoW | Propranolol Hydrochloride | Second Affiliated Hospital, School of Medicine, Zhejiang University | Hemangioma Liver | 08/23 | 12/24 | | |
NCT03384836: Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery |
|
|
| Recruiting | 1/2 | 47 | US | Laboratory Biomarker Analysis, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Propranolol Hydrochloride, Inderal, Innopran XL | Roswell Park Cancer Institute | Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7 | 01/25 | 01/25 | | |
| Active, not recruiting | 1/2 | 150 | US | Acetazolamide, Diamox, Atomoxetine, Strattera, NO Drug, Clonidine, Catapres, Entacapone, Comtan, Entacapone & Propranolol, Inderal, Atomoxetine & Propranolol, Indomethacin, Indocin, Mecamylamine, inversine, Isosorbide Dinitrate, Isordil, Melatonin, Midodrine, pro-amatine, Modafinil, provigil, Octreotide, sandostatin, Placebo, Propranolol, Modafinil & Propranolol, Provigil, Sertraline, Zoloft, IV Saline, NaCl solution (0.9%), Drinking Water, Breathing Device, memantine, Namenda, Abdominal binder | Satish R. Raj, National Center for Advancing Translational Sciences (NCATS) | Tachycardia, Chronic Orthostatic Intolerance | 12/25 | 12/25 | | |
