| propranolol / Generic mfg. |
| Recruiting | 1 | 24 | | | University of Queensland Diamantina Institute, NHMRC | Melanoma | | | | |
NCT02264093: Effects on the Airway Lumen of Talsaclidine in Combination With Propranolol in Comparison to the Effects of the Monosubstances in Healthy Elderly Male Volunteers |
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| Completed | 1 | 12 | Europe | Propranolol, Talsaclidine | Boehringer Ingelheim | Healthy | 02/00 | | | |
NCT02256722: In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects |
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| Completed | 1 | 12 | Europe | KUC 7483 CL, Bisoprolol, Propranolol, Acipimox, Salmeterol | Boehringer Ingelheim | Healthy | 11/05 | | | |
| Completed | 1 | 18 | Europe | Propranolol, Salbutamol, Ipratropium, Placebo | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 10/07 | 10/07 | | |
NCT00687700: A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers |
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| Completed | 1 | 23 | Europe | GSK961081, GSK961081 matching placebo, Propranolol, Propranolol matching placebo | Theravance Biopharma, GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 05/08 | 05/08 | | |
NCT00902161: A Single-Dose Crossover Study of MK0893 in Patients With Type 2 Diabetes (0893-019 AM4)(COMPLETED) |
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| Completed | 1 | 22 | US | MK0893, MK0893-matched Placebo, Propranolol Hydrochloride (HCL) | Merck Sharp & Dohme LLC | Type 2 Diabetes Mellitus | 10/09 | 11/09 | | |
NCT01284868: A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron. |
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| Completed | 1 | 12 | Europe | mirabegron, YM178, Bisoprolol, propranolol, placebo | Astellas Pharma Inc | Healthy Volunteers, Pharmacodynamics of Mirabegron | 11/09 | 11/09 | | |
NCT01263197: A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol |
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| Completed | 1 | 48 | US | LY2216684, albuterol, propranolol, placebo for LY2216684, placebo for albuterol, placebo for propranolol | Eli Lilly and Company | Major Depressive Disorder | 03/11 | 03/11 | | |
NCT00251602: Analysis of Atropine and Propranolol Induced Changes |
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| Completed | 1 | 24 | US | Atropine, Propranolol, Normal Saline, NS | National Institute on Aging (NIA) | Healthy | 08/12 | 08/12 | | |
NCT00688805: Effects of Propranolol on Responses to Drug-Related Imagery Scripts |
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| Terminated | 1 | 40 | US | Propranolol, Placebo | National Institute on Drug Abuse (NIDA) | Cocaine Dependence | 12/13 | 12/13 | | |
BBEmoMem_G, NCT02509559: Effects of Propranolol (vs. Placebo) on Information Processing During Presentation of Emotionally Arousing Pictures |
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| Completed | 1 | 8 | Europe | propranololhydrochloride, propanolol pharmacokinetics, placebo, placebo capsule, Net Station® System and compatible Geodesic Sensor Nets®, VITAPORT, ergoselect II 100/200, SpiroScout, Mobil-O-Graph® PWA, Saliva collection | University Medicine Greifswald | Emotions | 02/14 | 01/15 | | |
NCT01308944: Therapeutic Targeting of Stress Factors in Ovarian Cancer Patients |
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| Completed | 1 | 24 | US | Propranolol, Inderal | Washington University School of Medicine | Invasive Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer | 08/14 | 08/15 | | |
NCT02013492: Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery |
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| Completed | 1 | 1 | US | propranolol hydrochloride, Inderal, Correlative Studies | William Carson | Male Breast Cancer, Recurrent Melanoma, Stage IV Breast Cancer, Stage IV Melanoma, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Unspecified Adult Solid Tumor, Protocol Specific, Hepatocellular Carcinoma | 06/15 | 06/15 | | |
NCT00889096: Effects of Propranolol on the Encoding and Retrieval of Emotional Material After Single Dose Administration in Healthy Young Subjects |
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| Completed | 1 | 46 | Europe | propranolol, placebo | University Medicine Greifswald | Memory, Heart Rate, Skin Electric Conductance, Amylase, Propanolol | | | | |
| Completed | 1 | 9 | US | Propranolol, Both groups receive the same intervention | University of Wisconsin, Madison | Proliferative Diabetic Retinopathy | 12/15 | 12/15 | | |
2009-018102-22: A multicentre, open-label, repeated-dose, pharmacokinetic study of Propranolol in infants treated for proliferating infantile hemangiomas (IHs) requiring systemic therapy. |
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| Ongoing | 1 | 18 | Europe | V0400SB07, V0400SB07, | PIERRE FABRE DERMATOLOGIE | Proliferating Infantile Hemangioma | | | | |
NCT01851252: MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy |
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| Completed | 1 | 19 | RoW | Methacetin (with Breath testing device) | Meridian Bioscience, Inc. | Chronic Liver Disease, Cirrhosis, Esophageal Varices, Portal Hypertension, Bleeding | 08/17 | 08/17 | | |
NCT02467400: Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism |
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| Completed | 1 | 165 | US | Atenolol, Nebivolol, Propranolol, placebo | Mayo Clinic | Osteoporosis, Age-Related | 10/17 | 04/18 | | |
NCT03270644: A Study of Lasmiditan and Propranolol in Healthy Participants |
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| Completed | 1 | 44 | US | Lasmiditan, LY573144, Propranolol | Eli Lilly and Company | Healthy | 11/17 | 11/17 | | |
| Terminated | 1 | 15 | US | Propranolol 1, 20 mg propranolol, Propranolol 2, 10 mg propranolol, Placebo | University of Utah | Fibromyalgia Pain | 04/18 | 07/18 | | |
| Completed | 1 | 26 | US | Fat biopsy, Propranolol and fat biopsy, heavy water and fat biopsy | Philip Kern, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Obese, Normal Body Weight, Prediabetes, Metabolic Syndrome | 08/18 | 08/18 | | |
NCT03523650: Oral Propanolol for Surgically Inaccessible Cavernous Malformations |
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| Unknown status | 1 | 346 | US | Propranolol Oral Tablet, Placebo Oral Tablet | University of Virginia | Cavernous Malformations,Cerebral and/or Spinal | 01/19 | 01/19 | | |
| Active, not recruiting | 1 | 11 | US | Phentolamine, Regitine, Propranolol, Inderal, Placebo, Saline, Sodium Chloride Solution | University of Pennsylvania, National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type1diabetes, Hypoglycemia, Hypoglycemia Unawareness, Islet Cell Transplantation | 04/19 | 12/24 | | |
NCT01504126: Propranolol Hydrochloride and Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer |
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| Completed | 1 | 32 | US | Chemotherapy, Chemo, Chemotherapy (NOS), Chemotherapy, Cancer, General, Propranolol Hydrochloride, Inderal, Innopran XL, Quality-of-Life Assessment, Quality of Life Assessment, Therapeutic Conventional Surgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI), Sprint for Life | Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Fallopian Tube Undifferentiated Carcinoma, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mucinous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Adenocarcinoma, Ovarian Undifferentiated Carcinoma, Primary Peritoneal Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v6 and v7, Stage II Ovarian Cancer AJCC v6 and v7, Stage IIA Fallopian Tube Cancer AJCC v6 and v7, Stage IIA Ovarian Cancer AJCC V6 and v7, Stage IIB Fallopian Tube Cancer AJCC v6 and v7, Stage IIB Ovarian Cancer AJCC v6 and v7, Stage IIC Fallopian Tube Cancer AJCC v6 and v7, Stage IIC Ovarian Cancer AJCC v6 and v7, Stage III Fallopian Tube Cancer AJCC v7, Stage III Ovarian Cancer AJCC v6 and v7, Stage III Primary Peritoneal Cancer AJCC v7, Stage IIIA Fallopian Tube Cancer AJCC v7, Stage IIIA Ovarian Cancer AJCC v6 and v7, Stage IIIA Primary Peritoneal Cancer AJCC v7, Stage IIIB Fallopian Tube Cancer AJCC v7, Stage IIIB Ovarian Cancer AJCC v6 and v7, Stage IIIB Primary Peritoneal Cancer AJCC v7, Stage IIIC Fallopian Tube Cancer AJCC v7, Stage IIIC Ovarian Cancer AJCC v6 and v7, Stage IIIC Primary Peritoneal Cancer AJCC v7, Stage IV Fallopian Tube Cancer AJCC v6 and v7, Stage IV Ovarian Cancer AJCC v6 and v7, Stage IV Primary Peritoneal Cancer AJCC v7 | 08/19 | 08/19 | | |
NCT03882255: A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State |
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| Completed | 1 | 52 | Europe | Ponesimod dose range (2 - 20 mg), Placebo Propranolol, Propranolol 80 mg | Janssen Pharmaceutica N.V., Belgium | Healthy | 08/19 | 08/19 | | |
ChiCTR-OIh-17012140: The clinical research of propranolol in the therapy of gastrointestinal cancer in the preoperative |
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| Not yet recruiting | 1 | 80 | | propranolol ;Placebo | Department of Clinical Pharmacology, XiangYa Hospital, Central South University; XiangYa Hospital, Central South University, The National Natural Science Fund | gastrointestinal cancer | | | | |
ChiCTR-IPR-14005271: Research on approaches to improving cancer patients perioperative immunity and reducing postsurgical cancer recurrence |
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| Recruiting | 1 | 80 | | surgery ;surgery and propranolol ;surgery and parecoxib ;surgery, propranolol and parecoxib | The Third Xiangya Hospital of Central South University; The Third Xiangya Hospital of Central South Univer, National Natural Science Foundation, China | Breast cancer | | | | |
NCT01978457: Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction |
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| Terminated | 1 | 6 | US | cocaine hydrochloride, propranolol, placebo | Yale University | Cocaine Dependent Subjects | 12/19 | 12/19 | | |
NCT02897986: Study of a Propranolol (HEMANGIOL®) and Oral Metronomic Vinorelbine (NAVELBINE®) Combination for Children and Teenagers With Refractory/Relapsing Solid Tumors |
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| Unknown status | 1 | 54 | Europe | administration of a propranolol (HEMANGIOL®) and oral metronomic vinorelbine (NAVELBINE®) combination | Assistance Publique Hopitaux De Marseille | Pediatric Cancer | 01/20 | 01/21 | | |
NCT02871349: Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response |
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| Completed | 1 | 69 | US | Propranolol, Inderal, Hemangeol, Innopran, Placebo, Magnetic Resonance Imaging (MRI) | University of Missouri-Columbia, United States Department of Defense | Autism Spectrum Disorder | 08/20 | 08/20 | | |
NCT03245554: Clinical Research on Teratment of Gastrointestinal Cancer in the Preoperative by Propranolol |
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| Unknown status | 1 | 80 | RoW | Propranolol, placebo | Central South University | Gastrointestinal Cancer | 09/20 | 09/20 | | |
| Completed | 1 | 10 | US | Standing or upright tilt, Microneurography, QSweat, neck cuff stimulation, phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine, clonidine,yohimbine,metoclopramide,alpha-methyldopa, BodPod, Eye exam, Sleep study, Pain response testing, Metabolic chamber, Brain function studies, Bicycle Exercise Test | Vanderbilt University Medical Center | Autonomic Nervous System Diseases, Orthostatic Hypotension, Dopamine Beta-Hydroxylase Deficiency, Orthostatic Intolerance | 12/20 | 12/20 | | |
NCT04833218: Propranolol Versus Propranolol and Clonidine in Sympathetic Hyperactivity After Moderate Traumatic Brain Injury |
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| Active, not recruiting | 1 | 90 | RoW | Propranolol, Clonidine | Minia University | Traumatic Brain Injury | 06/21 | 07/21 | | |
| Terminated | 1 | 239 | US | Propranolol, Placebo oral capsule, Acute stress task, No stress task | Dana Bovbjerg, National Cancer Institute (NCI) | DNA Damage, Psychological Stress | 01/22 | 01/22 | | |
ChiCTR2200057295: A randomized controlled study of low-dose propranolol in the treatment of stroke-related sarcopenia |
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| Recruiting | 1 | 50 | | Propranolol 10 mg tid was given orally for 3 days ;Vitamin C tablets 100 mg tid were given orally for 3 days | The Third Affiliated Hospital of Sun Yat-sen University; The Third Affiliated Hospital of Sun Yat-sen University, self-funded | The stroke-related sarcopenia | | | | |
NCT05189977: A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline |
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| Terminated | 1 | 34 | US | Propranolol, Prazosin | Otsuka Pharmaceutical Development & Commercialization, Inc., Iqvia Pty Ltd | Post-traumatic Stress Disorder (PTSD) | 08/23 | 08/23 | | |
| Not yet recruiting | 1 | 50 | NA | Propranolol, Placebo | London Health Sciences Centre | TBI (Traumatic Brain Injury) | 04/25 | 09/25 | | |
NCT05256069: Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia |
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| Recruiting | 1 | 35 | US | Propranolol Pill, Placebo | University of Missouri-Columbia, American Heart Association | Vasodilation, Hypoxia | 07/24 | 07/24 | | |
| Enrolling by invitation | 1 | 150 | US | Propranolol Hydrochloride tablet, Reminder, Counterconditioning, Placebo | Icahn School of Medicine at Mount Sinai | Misophonia | 09/24 | 10/24 | | |
| Not yet recruiting | 1 | 75 | NA | Placebo, Propranolol, Gemtesa | University of Missouri-Columbia | Aging, Menopause, Hypoxia, Vasodilation | 07/25 | 07/25 | | |
NCT05960656: SGLT2 Inhibitors, Ketogenesis, and Ketoacidosis |
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| Recruiting | 1 | 169 | US | Empagliflozin 25 MG, Jardiance, Placebo, Placebo for empagliflozin, Pioglitazone 30mg, Actos, Pioglitazone 30mg + Empagliflozin (25 mg), Actos/Jardiance | The University of Texas Health Science Center at San Antonio, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type 2 Diabetes, Type 1 Diabetes | 06/27 | 06/27 | | |
NCT05219799: Sex Disparities in Hypoxic Vasodilation and Impact of Obesity |
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| Recruiting | 1 | 72 | US | Propranolol Hydrochloride, Isoproterenol, Phentolamine Mesylate, Norepinephrine | University of Missouri-Columbia | Obesity, Vasodilation, Healthy | 07/25 | 07/25 | | |
BRIO, NCT05979818: Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer |
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| Not yet recruiting | 1 | 6 | NA | Propranolol hydrochloride, Inderal, Sintilimab, Chemotherapy | Second Xiangya Hospital of Central South University, Innovent Biologics (Suzhou) Co. Ltd. | Non Small Cell Lung Cancer, Propranolol | 08/25 | 12/26 | | |
NCT05968690: Naltrexone and Propranolol Combined With Immunotherapy |
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| Recruiting | 1 | 12 | US | Propranolol, Naltrexone | Ryan Stephenson | Advanced Melanoma | 09/25 | 09/25 | | |
NCT04713657: Beta-blocker Administration for Cardiomyocyte Division |
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| Suspended | 1 | 40 | US | N-thymidine, Thymidine, Urine Collection, Echocardiogram, Cardiac MRI, Propranolol Hydrochloride, Propranolol, Placebo, Physical Exam, Specimen Collection | Weill Medical College of Cornell University, National Heart, Lung, and Blood Institute (NHLBI) | Tetralogy of Fallot, Double Outlet Right Ventricle | 12/30 | 12/30 | | |
| Recruiting | 1 | 20 | US | Propranolol, Magnetic Resonance Imaging (MRI), Placebo | University of Missouri-Columbia | Aphasia, Primary Progressive | 10/26 | 10/26 | | |
