Inflammation  >>  Isentress (raltegravir)  >>  Phase 4
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10 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Isentress (raltegravir) / Merck (MSD)
NCT00782301: Maraviroc Versus Etravirine In Combination With Antiretroviral Therapy In Drug Experienced HIV And Hepatitis Co-Infected Patients

Withdrawn
4
0
US, Canada, Europe
maraviroc, Selzentry, etravirine
ViiV Healthcare, Pfizer
Hepatitis B, Human Immunodeficiency Virus, Hepatitis C, Chronic
02/10
02/10
NCT01529749 / 2011-002071-42: Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively Treated

Completed
4
48
Europe
EFV/FTC/TDF + Losartan, EFV/FTC/TDF, FTC/TDF + MK-0518, FTC/TDF+MK-0518+Losartan
Felipe Garcia
HIV-1 Infection
03/12
02/16
NCT01225705 / 2009-015904-24: Safety Study of Raltegravir in HIV/HCV Co-infected Patients

Withdrawn
4
0
Europe
raltegravir, Atazanavir/ritonavir
University Hospital, Bonn, Dr. Axel Baumgarten, Berlin, Dr. Christoph Stephan, Frankfurt/M, Dr. Stefan Esser, Essen, Dr. Keikawus Arastéh, Berlin, Prof. Dr. Hans-Jürgen Stellbrink, Hamburg, Dr. Thomas Lutz, Frankfurt/M, Dr. Jörg Gölz , Berlin
HIV, Hepatitis C
08/12
08/12
NCT01105611 / 2010-018326-39: Safety and Efficacy Study Comparing Raltegravir to a Protease Inhibitor in Treatment-naïve, HIV/Hepatitis C Drug Users

Unknown status
4
40
Europe
Raltegravir, Isentress™, Atazanavir/Ritonavir, Reyataz™ (Atazanavir), Norvir™ (Ritonavir)
St. James's Hospital, Ireland
HIV Infections, Hepatitis C
12/12
12/12
NCT00843713: Effect of Raltegravir on Endothelial Function in HIV-Infected Patients

Completed
4
56
US
raltegravir, Placebo
University of California, San Francisco, National Heart, Lung, and Blood Institute (NHLBI), Merck Sharp & Dohme LLC
HIV Infection, Inflammation, Cardiovascular Disease, HIV Infections
11/13
02/14
RASSTER, NCT01453933 / 2011-003298-26: RAltegravir Switch STudy: Effects on Endothelial Recovery

Unknown status
4
24
Europe
raltegravir, Isentress
UMC Utrecht, Merck Sharp & Dohme LLC
HIV Infection, Endothelial Dysfunction
10/14
12/14
NCT01285050: Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds

Completed
4
20
US
Antiretroviral therapy (ART), raltegravir, Isentress, Emtricitabine and tenofovir disoproxil fumarate, Truvada
Johns Hopkins University, National Institute on Drug Abuse (NIDA)
HIV Infection, Hepatitis C
04/15
04/15
NCT01147107: Hepatic Safety of Raltegravir Versus Efavirenz as HIV Therapy for Patients With HIV and HCV Coinfection

Completed
4
80
RoW
Raltegravir, Isentress, Efavirenz, Sustiva
University of Hawaii, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Viet Tiep General Hospital, Hai Phong, Vietnam, Oxford University Clinical Research Unit, Vietnam
Hepatitis C, Chronic, HIV Infection
06/16
06/21
NCT02577042 / 2015-002682-30: Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen

Completed
4
42
Europe
Raltegravir, PI-based regimen, Atorvastatin
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Aging-related Inflammation in HIV-infected Patients
06/18
06/18
NCT02691065: Protease Inhibitor vs. Raltegravir-based ART and Inflammation in HIV Infection

Completed
4
6
Canada
Integrase Inhibitor
McGill University Health Centre/Research Institute of the McGill University Health Centre, Merck Sharp & Dohme LLC
HIV
03/21
03/21

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