Endocrine System Diseases  >>  pegylated liposomal doxorubicin  >>  Phase 2
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17 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
pegylated liposomal doxorubicin / Generic mfg.
NCT00189410: Combination Chemotherapy Consisting of Pegylated Liposomal Doxorubicin and Carboplatin in Malignant Gynecologic Tumours

Completed
2
140
Europe
Pegylated Liposomal Doxorubicin and Carboplatin
AGO Study Group, MedServ. GmbH, Wiesbaden, Essex Pharma GmbH
Cancer of the Ovary Treated as 2nd Line Therapy, Muellerian Mixed Tumours, Tumours of the Uterus, Cervical Cancers, Non-Epithelial Ovarian Tumours
09/05
09/06
NCT00097019: A Study of Bevacizumab in Ovarian Cancer or Primary Peritoneal Cancer Where Doxil or Topotecan Therapy Has Failed

Completed
2
53
NA
bevacizumab
Genentech, Inc.
Ovarian Cancer
05/06
05/06
NCT00312650: Doxil and Gemcitabine in Recurrent Ovarian Cancer

Terminated
2
24
US
liposomal doxorubicin and gemcitabine
Women and Infants Hospital of Rhode Island, Ortho Biotech, Inc.
Ovarian Carcinoma
05/06
05/06
NCT00216645: Phase II Clinical Study of Pegylated Liposomal Doxorubicin Hydrochloride Injection as 2nd-line or Later Therapy in Patients With Mullerian Carcinoma (Epithelial Ovarian Carcinoma, Primary Carcinoma of Fallopian Tube, Peritoneal Carcinoma) Having Prior Platinum-Based Chemotherapy

Completed
2
74
Japan
doxorubicin hydrochloride
Janssen Pharmaceutical K.K.
Ovarian Neoplasms
 
11/06
NCT00780039: A Study to Evaluate the Safety and Efficacy of Caelyx in Combination With Carboplatin in Patients With Ovarian Cancer Recurrent Within Six to Twelve Months After Initial Carboplatin and Paclitaxel Chemotherapy (P03625)

Completed
2
58
NA
Pegylated Liposomal Doxorubicin, SCH 200746, Carboplatin
Merck Sharp & Dohme LLC, Princess Margaret Hospital, Canada
Ovarian Neoplasms
09/07
09/07
NCT00426127: Docetaxel and Liposomal Doxorubicin Chemotherapy With Enoxaparin in Patients With Advanced Pancreatic Cancer

Terminated
2
2
US
Docetaxel, Taxotere, Liposomal Doxorubicin, caelyx, Enoxaparin, Lovenox
University of Iowa, Aventis Pharmaceuticals
Pancreatic Cancer
01/09
08/09
NCT00523380 / 2007-001506-25: Efficacy Study of Recombinant Interleukin-21 in the Treatment of Ovarian Cancer

Completed
2
10
Europe
recombinant interleukin-21, rIL-21, NN028, caelyx (pegylated liposomal doxorubicin)
Novo Nordisk A/S
Cancer, Ovarian Cancer
01/09
01/09
NCT00610792 / 2005-003962-40: Phase 2 Study of Twice Weekly VELCADE and CAELYX in Patients With Ovarian Cancer Failing Platinum Containing Regimens

Withdrawn
2
91
Europe
bortezomib, VELCADE, pegylated liposomal doxorubicin, CAELYX
Millennium Pharmaceuticals, Inc.
Ovarian Cancer
09/09
 
PRECEDENT, NCT00722592: Platinum Resistant Ovarian Cancer Evaluation of Doxil and Vintafolide (MK-8109, EC145) Combination Therapy (8109-009, EC-FV-04)

Checkmark SGO 2014
Mar 2014 - Mar 2014: SGO 2014
Checkmark SGO 2014
Mar 2014 - Mar 2014: SGO 2014
Checkmark In pts with platinum-resistant ovarian cancer
More
Completed
2
162
US
Vintafolide, EC145, pegylated liposomal doxorubicin (PLD), Doxil®, Caelyx®, EC20, 99mTc-EC20
Endocyte
Ovarian Cancer
09/10
12/12
NCT00698451: A Study of Carboplatin and DOXIL Plus Bevacizumab in Patients With Platinum Sensitive Recurrent Ovarian, Fallopian Tube and Primary Peritoneal Cancers

Checkmark P2 data (Ovarian)
Jun 2012 - Jun 2012: P2 data (Ovarian)
Completed
2
54
US
doxorubicin HCL liposome; bevacizumab; carboplatin
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Centocor Ortho Biotech Services, L.L.C.
Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
10/10
10/10
NCT00945139: Study of Bevacizumab/Doxil in Treatment of Platinum-Resistant/Refractory Ovarian Cancer (CA)

Checkmark P2 data (Ovarian)
Aug 2012 - Aug 2012: P2 data (Ovarian)
Completed
2
46
US
Doxil, Doxorubicin, Avastin, Bevacizumab
New Mexico Cancer Care Alliance, Genentech, Inc., NYU Langone Health
Ovarian Cancer
12/10
08/11
NCT00248248: DOXIL for Consolidation Therapy in Ovarian Cancer.

Completed
2
45
US
liposomal doxorubicin
Southeastern Gynecologic Oncology, Ortho Biotech, Inc.
Ovarian Neoplasm
10/11
10/11
NCT01113957 / 2009-015082-31: A Trial of ABT-888 in Combination With Temozolomide Versus Pegylated Liposomal Doxorubicin Alone in Ovarian Cancer

Completed
2
168
US, Canada, Europe, RoW
ABT-888, ABT-888, veliparib, pegylated liposomal doxorubicin, doxil/caelyx, temozolomide, temozolomide, temodar/temodal
AbbVie (prior sponsor, Abbott)
Ovarian Cancer
06/13
06/13
NCT01121406 / 2009-015770-35: BI 6727 (Volasertib) Randomised Trial in Ovarian Cancer

Completed
2
110
Europe
Paclitaxel, Gemcitabine, Topotecan, Pegylated liposomal doxorubicin (PLD), BI 6727
Boehringer Ingelheim
Ovarian Neoplasms
06/14
06/14
NCT01991210 / 2012-005776-34: A Study of DNIB0600A in Comparison With Pegylated Liposomal Doxorubicin (PLD) in Participants With Platinum-Resistant Ovarian Cancer (PROC)

Checkmark ASCO 2016
May 2016 - May 2016: ASCO 2016
Terminated
2
95
US, Canada, Europe
DNIB0600A, RO5541081, PLD
Genentech, Inc.
Ovarian Cancer
08/16
08/16
NCT00052065: TLK286 in Combination With Doxil in Platinum Refractory or Resistant Ovarian Cancer

Completed
1/2
28
US
TLK286
Telik
Ovarian Neoplasms
03/06
03/06
NCT00562185: Doxorubicin and Carboplatin in Treating Patients With Recurrent Ovarian Cancer

Withdrawn
1/2
0
US
carboplatin, doxorubicin hydrochloride
University of Texas Southwestern Medical Center, Ortho Biotech Clinical Affairs, L.L.C.
Ovarian Cancer
03/09
03/09

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