Sarcoma  >>  ifosfamide  >>  Phase N/A
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20 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ifosfamide / Generic mfg.
NCT00645632: Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma

Completed
N/A
60
US
cisplatin, doxorubicin hydrochloride, ifosfamide, methotrexate, adjuvant therapy, neoadjuvant therapy, therapeutic conventional surgery
Mayo Clinic, National Cancer Institute (NCI)
Sarcoma
01/95
01/08
NCT00283621: Aranesp and Neulasta in Patients With Sarcoma Receiving Adriamycin and Ifosfamide

Completed
N/A
51
US
Aranesp (darbepoetin alfa), Neulasta (pegfilgrastim), Adriamycin, Doxorubicin Hydrocholoride, Adriamycin PFS, Adriamycin RDF, Ifosfamide, Ifex
M.D. Anderson Cancer Center, Amgen
Sarcoma
04/06
04/06
NCT00618813: Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Completed
N/A
35
US
radiation therapy, irradiation, radiotherapy, therapy, radiation, therapeutic conventional surgery, etoposide, EPEG, VP-16, VP-16-213, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, doxorubicin hydrochloride, ADM, ADR, Adria, Adriamycin PFS, Adriamycin RDF, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, vincristine sulfate, leurocristine sulfate, VCR, Vincasar PFS, topotecan hydrochloride, hycamptamine, Hycamtin, SKF S-104864-A, TOPO, filgrastim, G-CSF, Neupogen
Children's Oncology Group, National Cancer Institute (NCI)
Ewing Sarcoma of Bone, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
03/10
 
NCT00673179: Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy

Terminated
N/A
7
US
Doxorubicin, AD, Hydroxydaunomycin hydrochloride, Cisplatin, Paraplatin®, Methotrexate, Leucovorin, Dexrazoxane, Zinecard, Ifosfamide, Ifex, Questionnaire, Survey, Gemcitabine, Gemzar, Gemcitabine Hydrochloride, Sargramostim, GM-CSF, Leukine™, Surgery, Mesna, Mesnex
M.D. Anderson Cancer Center
Osteosarcoma
11/10
11/10
NCT00410488: Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)

Completed
N/A
51
US
Palonosetron - Single Dose, Aloxi, Palonosetron - Triple Dose, Adriamycin, Doxorubicin, Doxorubicin Hydrochloride, Adriamycin PFS, Adrimaycin RDF, Rubex, Ifosfamide chemotherapy (AI), Ifex, Zinecard, Dexrazoxane, Mesna, mesnex, Vincristine, Dexamethasone, Decadron, Dexamethasone acetate
M.D. Anderson Cancer Center, Eisai Inc.
Sarcoma, Nausea, Vomiting
06/11
06/11
NCT00346125: PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma

Completed
N/A
70
US
pegfilgrastim, Neulasta(R), doxorubicin hydrochloride, Doxorubicin, Adriamycin, ifosfamide, Mitoxana, Ifex, pegylated liposomal doxorubicin hydrochloride, doxorubicin-hydrochloride-liposome, conventional surgery, fludeoxyglucose F 18, FDG
Masonic Cancer Center, University of Minnesota
Sarcoma
07/13
07/22
NCT00514345: CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide

Unknown status
N/A
300
Europe
gene expression analysis, polymorphism analysis, management of therapy complications
Children's Cancer and Leukaemia Group
Chemotherapeutic Agent Toxicity, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
 
 
NCT01299506: Study in Patients With Advanced Soft Tissue Sarcoma (STS) After Failure of Anthracyclines and/or Ifosfamide

Completed
N/A
102
Europe
PharmaMar
Soft Tissue Sarcoma
04/14
04/14
EUROBOSS, NCT02986503: European Study in Bone Sarcoma Patients Over 40 Years

Completed
N/A
100
Europe
Doxorubicin+cisplatin+ifosfamide, Doxorubicin,cisplatin,ifosfamide, Doxorubicin+cisplatin+ifosfamide+methotrexate, Doxorubicin,cisplatin,ifosfamide,methotrexate
Italian Sarcoma Group, Scandinavian Sarcoma Group, Cooperative Osteosarcoma Study Group
Spindle Cell Sarcoma of Bone, Osteosarcoma
12/15
11/16
NCT01490060: Fosaprepitant in Patients Receiving Ifosfamide-based Regimen

Completed
N/A
47
US
Fosaprepitant, Fosaprepitant Dimeglumine, Dexamethasone, Dexamethasone acetate, Decadron, 5HT3 receptor antagonist, Ifosfamide-based chemotherapy (AI), Doxorubicin, Rubex, Adriamycin, Adriamycin RDF, Adriamycin PFS, Doxorubicin Hydrochloride, Mesna, Mesnex, Ifosfamide, Ifex, Vincristine
M.D. Anderson Cancer Center, Merck Sharp & Dohme LLC
Sarcoma, Chemotherapy-induced Nausea and Vomiting, Effects of Chemotherapy, Adverse Effects of Medical Drugs
03/16
03/16
NCT01795430: Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

Withdrawn
N/A
0
US
etoposide, EPEG, VP-16, VP-16-213, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, intensity-modulated radiation therapy, IMRT, topotecan hydrochloride, hycamptamine, Hycamtin, SKF S-104864-A, TOPO, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, melphalan, Alkeran, CB-3025, L-PAM, L-phenylalanine mustard, L-Sarcolysin, autologous hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, PBPC transplantation, PBSC transplantation, peripheral blood progenitor cell transplantation, transplantation, peripheral blood stem cell, autologous bone marrow transplantation, ABMT, bone marrow transplantation, autologous, transplantation, autologous bone marrow
City of Hope Medical Center, National Cancer Institute (NCI)
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
03/18
 
NCT01446809: Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma

Completed
N/A
23
US
Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, External Beam Radiation Therapy, Definitive Radiation Therapy, EBRT, External Beam Radiotherapy, External Beam RT, external radiation, External Radiation Therapy, external-beam radiation, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Pazopanib Hydrochloride, GW786034B, Votrient, Pharmacological Study, Placebo, placebo therapy, PLCB, sham therapy, Therapeutic Conventional Surgery
University of Washington, National Cancer Institute (NCI)
Stage IIA Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
01/19
01/19
NCT03360760: Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

Recruiting
N/A
100
RoW
Doxorubicin, Adriamycin, Cisplatin, cisplatinum, platamin, Methotrexate, HD-MTX, Ifosfamide, ifosphamide, definitive surgery, pre surgical chemotherapy, neoadjuvant chemotherapy
Peking University People's Hospital
Osteosarcoma of Pelvis
02/20
02/25
NCT04690231: Apatinib + Ifosfamide and Etoposide for Relapsed or Refractory Osteosarcoma

Completed
N/A
79
RoW
Apatinib Mesylate, ifosfamide and etoposide
Peking University People's Hospital, Peking University Shougang Hospital
Effect of Drug, Toxicity, Drug, Secondary Resistance
03/21
06/21
ChiCTR1900024967: Amroitinib hydrochloride combined with AI (doxorubicin + ifosfamide) for the treatment of high-grade soft tissue sarcomas with difficult surgical resection: a prospective, single arm, multi-center clinical study

Recruiting
N/A
78
 
Amroitinib hydrochloride
Beijing Jishuitan Hospital; Xijing Hospital, Military Medical University of The Air Force; Beijing Jishuitan Hospital, CHIATAI TIANQING
soft tissue sarcoma
 
 
ChiCTR2100053594: Efficacy and safety of eribulin monotherapy or combination therapy in Chinese adults with soft tissue sarcoma

Not yet recruiting
N/A
 
Anthracycline-based drugs ;Ifosfamide-based ;Other chemotherapy options ;Combined molecular targeted therapy ;Combination immune checkpoint inhibitor therapy
Zhongshan Hospital, Fudan University; Zhongshan Hospital, Fudan University, self-funded
soft tissue sarcoma (STS)
 
 
ChiCTR2000028961: Combination of high-throughput sequencing and primary cell culture as an exploratory study of individualized treatment of malignant tumors: phase 2 clinical trial of sintilimab for retroperitoneal dedifferentiation of liposarcoma

Not yet recruiting
N/A
30
 
Neoadjuvant sintilimab monotherapy ;Neoadjuvant sintilimab combined with epirubicin and/or ifosfamide
Department of Urology, Shanghai Changhai Hospital, the Second Military Medical University, Shanghai, China; Second Military Medical University, Innovent Biologics, Inc.
retroperitoneal dedifferentiated liposarcoma
 
 
NCT01505569: Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Completed
N/A
44
US
Ifosfamide, Mitoxana, Ifex, Etoposide, Eposin, Etopophos, Vepesid, VP-16, Mesna, Uromitexan, Mesnex, G-CSF, Granulocyte colony-stimulating factor, Busulfan, Busulfex, Melphalan, 50 mg/m2 IV over 30 min, Thiotepa, Thioplex, Autologous stem cell infusion, Radiation, Carboplatin, Paraplatin, Paclitaxel, Taxol, Onxal, Leukapheresis, Anti-seizure prophylaxis, Ursodiol
Masonic Cancer Center, University of Minnesota
Ewing's Family Tumors, Renal Tumors, Hepatoblastoma, Rhabdomyosarcoma, Soft Tissue Sarcoma, Primary Malignant Brain Neoplasms, Retinoblastoma, Medulloblastoma, Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET), Atypical Teratoid/Rhabdoid Tumor (AT/RT), CNS Tumors, Germ Cell Tumors
02/24
02/24
NCT06451302: Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort Study

Active, not recruiting
N/A
100
RoW
cyclophosphamide, adriamycin, vincristine，Ifosfamide，etoposide, vinorelbine
Yizhuo Zhang
Ewing Sarcoma, Risk Stratification
05/27
12/27
ChiCTR2100051933: A non-randomized controlled, open, multi-center clinical study to compare doxorubicin hydrochloride liposome injection versus doxorubicin in the treatment of osteosarcoma

Not yet recruiting
N/A
200
 
Methotrexate+Ifosfamide+Doxorubicin Hydrochloride Liposome Injection+Cisplatin ;Methotrexate+Ifosfamide+Doxorubicin Hydrochloride+Cisplatin
Beijing Jishuitan Hospital; Beijing Jishuitan Hospital, CSPC Ouyi Pharmaceutical Co., Ltd.
osteosarcoma
 
 

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