Sarcoma  >>  ifosfamide  >>  Phase 2
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87 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ifosfamide / Generic mfg.
SAKK 57/93, NCT00002526: Chemotherapy in Treating Patients With Advanced Sarcoma

Completed
2
20
Europe
filgrastim, doxorubicin hydrochloride, ifosfamide
Swiss Group for Clinical Cancer Research
Ovarian Cancer, Sarcoma
09/95
09/95
NCT00003776: Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Completed
2
US
filgrastim, cisplatin, doxorubicin hydrochloride, ifosfamide, leucovorin calcium, methotrexate, trimetrexate glucuronate, surgical procedure
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Sarcoma
03/00
03/00
NCT00002804: Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

Completed
2
43
US, Europe
filgrastim, Granulocyte-Colony Stimulating Factor, Neupogen, G-CSF, doxorubicin hydrochloride, Adriamycin, NSC#123127, ifosfamide, Isophosphamide, IFEX, mesna, Sodium 2-Mercaptoethane Sulfonate, Mesnex, Urimetexan, NSC#113891, vincristine sulfate, VCR, Oncovin, NSC#67574, conventional surgery, brachytherapy, low-LET cobalt-60 gamma ray therapy, low-LET electron therapy, low-LET photon therapy
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
06/00
04/06
NCT00165139: Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas

Completed
2
20
US
Vincristine, Cyclophosphamide, Adriamycin, Etoposide (VP-16), Cisplatin, Carboplatin, Melphalan, Ifosfamide, G-CSF (granulocyte-colony stimulating factor), Mesna
Dana-Farber Cancer Institute, Boston Children's Hospital, Children's Hospital of Philadelphia
Neuroblastoma, Ewings Sarcoma, Non-rhabdomyosarcoma Soft Tissue Sarcoma
11/00
02/09
NCT00003657: High-dose ICE With Amifostine

Completed
2
24
US
filgrastim, Amifostine, Ethyol®, Carboplatin, Paraplatin, Etoposide, Toposar, VePesid, Etopophos, Ifosfamide, Ifex, peripheral blood stem cell transplantation
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Bladder Cancer, Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Extragonadal Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer, Lung Cancer, Ovarian Cancer, Sarcoma, Testicular Germ Cell Tumor, Unspecified Adult Solid Tumor, Protocol Specific
11/00
06/02
NCT00003683: Combination Chemotherapy in Treating Patients With Metastatic Kidney Cancer

Completed
2
40
Europe
doxorubicin hydrochloride, ifosfamide
UNICANCER
Kidney Cancer
11/00
04/02
NCT00002974: Whole-Body Hyperthermia Plus Chemotherapy in Treating Patients With Advanced Sarcoma

Completed
2
34
US
carboplatin, etoposide, ifosfamide, hyperthermia treatment
University of Wisconsin, Madison, National Cancer Institute (NCI)
Sarcoma
07/01
04/03
NCT00002791: Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Soft Tissue Sarcoma

Completed
2
US, Canada, RoW
filgrastim, dacarbazine, doxorubicin hydrochloride, ifosfamide, mesna, conventional surgery, brachytherapy, intraoperative radiation therapy, radioisotope therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI), Eastern Cooperative Oncology Group
Sarcoma
05/02
11/13
NCT00002643: Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Completed
2
130
US, Canada, Europe, RoW
filgrastim, amifostine trihydrate, cyclophosphamide, doxorubicin hydrochloride, etoposide, ifosfamide, topotecan hydrochloride, vincristine sulfate, conventional surgery, low-LET cobalt-60 gamma ray therapy, low-LET electron therapy, low-LET photon therapy
National Cancer Institute (NCI), Children's Cancer Group
Neutropenia, Sarcoma
06/03
 
NCT00003292: S9624 Ifosfamide in Treating Patients With Meningeal Tumors

Terminated
2
7
US, RoW
ifosfamide
Southwest Oncology Group, National Cancer Institute (NCI), Eastern Cooperative Oncology Group
Chondrosarcoma, Adult Fibrosarcoma, Adult Leiomyosarcoma, Adult Rhabdomyosarcoma, Adult Malignant Meningioma, Adult Brain Malignant Hemangiopericytoma
01/04
01/04
NCT00002466: Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer

Completed
2
US
cyclophosphamide, doxorubicin hydrochloride, etoposide, ifosfamide, vincristine sulfate, conventional surgery, radiation therapy
Memorial Sloan Kettering Cancer Center
Kidney Cancer, Sarcoma
05/05
05/05
NCT00023998: Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Completed
2
80
US
doxorubicin hydrochloride, ADM, ADR, Adria, Adriamycin PFS, Adriamycin RDF, cisplatin, CACP, CDDP, CPDD, DDP, methotrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, leucovorin calcium, CF, CFR, LV, filgrastim, G-CSF, Neupogen, therapeutic conventional surgery, radiation therapy, irradiation, radiotherapy, therapy, radiation, etoposide, EPEG, VP-16, VP-16-213, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, trastuzumab, anti-c-erB-2, Herceptin, MOAB HER2, laboratory biomarker analysis
National Cancer Institute (NCI)
Metastatic Osteosarcoma
11/05
05/07
NCT00145639: Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma

Completed
2
80
US, RoW
Ifosfamide, Carboplatin, Doxorubicin, Limb Sparing
St. Jude Children's Research Hospital, Immunex/Berlex, National Institutes of Health (NIH)
Osteosarcoma
05/06
05/06
NCT00652860: Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery

Completed
2
39
US
aerosol sargramostim, sargramostim, cisplatin, doxorubicin hydrochloride, ifosfamide, mitomycin C, flow cytometry, immunological diagnostic method, laboratory biomarker analysis, adjuvant therapy, multimodality therapy, neoadjuvant therapy, therapeutic conventional surgery, intraoperative radiation therapy, selective external radiation therapy
Mayo Clinic, National Cancer Institute (NCI)
Metastatic Cancer, Sarcoma
11/06
 
NCT00204646: Neoadjuvant Adriamycin and Ifosfamide Plus High-Dose ICE in Patients With Soft Tissue Sarcoma (STS)

Completed
2
Europe
Adriamycin, Ifosfamide, Etoposide, Carboplatin
University Hospital Tuebingen
Sarcoma, Soft Tissue
 
12/06
NCT00025363: Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Completed
2
150
US
vincristine sulfate, leurocristine sulfate, VCR, Vincasar PFS, irinotecan hydrochloride, Campto, Camptosar, CPT-11, irinotecan, U-101440E, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, doxorubicin hydrochloride, ADM, ADR, Adria, Adriamycin PFS, Adriamycin RDF, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, etoposide, EPEG, VP-16, VP-16-213, tirapazamine, SR 4233, Tirazone, WIN 59075, filgrastim, G-CSF, Neupogen, sargramostim, GM-CSF, Leukine, Prokine, pharmacological study, pharmacological studies, pharmacogenomic studies, Pharmacogenomic Study, laboratory biomarker analysis
National Cancer Institute (NCI)
Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma, Embryonal-botryoid Childhood Rhabdomyosarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Childhood Rhabdomyosarcoma
10/07
 
NCT00072280: Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Terminated
2
7
US, Canada, RoW
dactinomycin, DACT, Actinomycin-D, Cosmegen, NSC #3053, cyclophosphamide, Cytoxan, NSC #26271, etoposide, ETOP, VePesid, Etopophos, VP-16, NSC #141540, ifosfamide, Isophosphamide, Iphosphamide, Z4942, Ifex, NSC #109724, vincristine sulfate, Oncovin, VCR, LCR, NSC #67574, Conventional Surgery, MESNA (mercaptoethane sulfonate), Sodium 2-mercaptoethane sulfonate, UCB 3983, Mesnex, NSC #113891, Filgrastim, Granulocyte Colony-Stimulating Factor, r-metHuG-CSF, G-CSF, Neupogen, NSC #614629
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
03/08
03/08
NCT00061893: Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

Completed
2
38
Canada, US, RoW
celecoxib, cyclophosphamide, doxorubicin hydrochloride, etoposide, ifosfamide, vinblastine sulfate, vincristine sulfate, conventional surgery, radiation therapy, MESNA, Filgrastim, G-CSF
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
04/08
12/13
NCT00060944: A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

Completed
2
271
US, Canada, Europe, RoW
Yondelis, Dexamethasone
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., PharmaMar
Liposarcoma, Leiomyosarcoma
05/08
05/08
NCT00245011: Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma

Completed
2
11
US
filgrastim, Neupogen, ifosfamide, Ifex, peripheral blood stem cell transplantation, Sm-EDTMP (low dose), sm-EDTMP (higher dose)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI)
Sarcoma
10/08
03/09
NCT00267046: Evaluate PKs and Efficacy Assessment of Palifermin in Patients With Sarcoma

Completed
2
49
US
Palifermin, Placebo, Adriamycin (Doxorubicin), Adriamycin, Ifosfamide, Vincristine, Cisplatin, CDDP, Platinol
M.D. Anderson Cancer Center
Sarcoma, Oral Mucositis
07/09
07/09
NCT00025441: Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Completed
2
Europe
dactinomycin, filgrastim, carboplatin, cyclophosphamide, doxorubicin hydrochloride, epirubicin hydrochloride, etoposide, ifosfamide, vincristine sulfate, peripheral blood stem cell transplantation, radiation therapy
Societe Internationale d'Oncologie Pediatrique, Children's Cancer and Leukaemia Group, Societe Francaise Oncologie Pediatrique
Ovarian Cancer, Sarcoma, Small Intestine Cancer
 
03/10
NCT00880542: Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery

Terminated
2
7
US
sorafenib, Ifosfamide
Jonsson Comprehensive Cancer Center
Sarcoma
11/10
 
NCT00089544: Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

Terminated
2
23
US
Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Filgrastim, FILGRASTIM, LICENSE HOLDER UNSPECIFIED, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tevagrastim, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, irradiation, RADIATION, Radiotherapeutics, radiotherapy, RT, Therapy, Radiation, Thalidomide, (+)-Thalidomide, (-)-Thalidomide, .alpha.-Phthalimidoglutarimide, 2, 6-Dioxo-3-phthalimidopiperidine, Alpha-Phthalimidoglutarimide, Contergan, Distaval, Kevadon, N-(2,6-Dioxo-3-piperidyl)phthalimide, N-Phthaloylglutamimide, N-Phthalylglutamic Acid Imide, Neurosedyn, Pantosediv, Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (+)-, Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (-)-, Sedalis, Sedoval K-17, Softenon, Synovir, Talimol, Thalomid, Therapeutic Conventional Surgery
National Cancer Institute (NCI), Radiation Therapy Oncology Group
Recurrent Adult Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma AJCC v7, Stage II Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7
09/11
11/13
NCT01102608 / 2007-005755-42: Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue Sarcoma

Completed
2
32
Europe
Ifosfamide
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma
10/11
12/11
NCT00544778: Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

Terminated
2
7
US
filgrastim, dexrazoxane hydrochloride, doxorubicin hydrochloride, ifosfamide, irinotecan hydrochloride, protein expression analysis, immunoenzyme technique, adjuvant therapy, conventional surgery, neoadjuvant therapy, radiation therapy
City of Hope Medical Center, National Cancer Institute (NCI)
Sarcoma
11/11
 
NCT00965172: Caphosol in Sarcoma Patients With Mucositis

Completed
2
30
US
Caphosol, calcium phosphate, Baking Soda, Sodium Bicarbonate
M.D. Anderson Cancer Center
Sarcoma, Oral Mucositis
02/12
02/12
SSGXX, NCT00790244 / 2007-001152-39: A Scandinavian Sarcoma Group Protocol for Patients With High-risk Soft Tissue Sarcoma of the Extremities and Trunk Wall

Recruiting
2
188
Europe
doxorubicin , ifosfamide, Doxorubicin, Holoxan, doxorubicin, ifosfamide
Oslo University Hospital, Scandinavian Sarcoma Group
Soft Tissue Sarcoma, Non Metastatic Disease
10/12
10/22
NCT00189137: Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma

Completed
2
84
US
ifosfamide and doxorubicin vs gemcitabine and docetaxel
University of Michigan Rogel Cancer Center
Sarcoma, Soft Tissue
11/12
10/15
NCT00541411: Phase II Pilot Study of Vincristine, Adriamycin, Actinomycin D, Ifosfamide Combination Chemotherapy in Ewing's Sarcoma

Unknown status
2
10
NA
Vincristine, Actinomycin-D, Ifosfamide
King Faisal Specialist Hospital & Research Center
Ewing's Sarcoma
06/13
06/13
NCT00017160: Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Withdrawn
2
0
US, Canada
doxorubicin, filgrastim, ifosfamide, biological response modifier therapy, brachytherapy, chemotherapy, colony-stimulating factor therapy, conventional surgery, cytokine therapy, intraoperative radiotherapy, radiation therapy, surgery
Radiation Therapy Oncology Group, National Cancer Institute (NCI)
Stage III Adult Soft Tissue Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Stage IVA Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma, Stage IIC Adult Soft Tissue Sarcoma
 
 
NCT00304083: Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

Completed
2
48
US
filgrastim, doxorubicin hydrochloride, etoposide, ifosfamide, conventional surgery, radiation therapy
Sarcoma Alliance for Research through Collaboration, National Cancer Institute (NCI)
Neurofibromatosis Type 1, Sarcoma
06/14
06/14
NCT00667342: A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

Completed
2
43
US
Bevacizumab, rhuMAb VEGF, Avastin®, Cisplatin, Platinol-AQ®, Doxorubicin, Adriamycin®, Methotrexate, MTX, Ifosfamide, Ifex®, etoposide, VP-16, Vepesid®, Surgery, Radiotherapy
St. Jude Children's Research Hospital, Genentech, Inc.
Osteosarcoma, Malignant Fibrous Histiocytoma (MFH) of Bone
08/14
08/17
NCT00002601: Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

Completed
2
13
US
filgrastim, cisplatin, doxorubicin hydrochloride, ifosfamide, melphalan, peripheral blood stem cell transplantation
City of Hope Medical Center, National Cancer Institute (NCI)
Sarcoma
09/14
09/14
2013-000762-11: A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in High Grade Uterine Sarcoma (HGUtS) after stabilization or response to doxorubicin +/- ifosfamide following surgery or in metastatic first line treatment

Ongoing
2
90
Europe, RoW
Cabozantinib, XL184, Film-coated tablet
European Organisation for Research and Treatment of Cancer (EORTC), Exelixis, European Organisation for Research and Treatment of Cancer (EORTC)
High Grade Undifferentiated Uterine Sarcoma (HGUS), Uterine Sarcoma, Diseases [C] - Cancer [C04]
 
 
NCT01946529: Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

Active, not recruiting
2
24
US
vincristine, Oncovin(R), doxorubicin, Adriamycin(R), cyclophosphamide, Cytoxan(R), ifosfamide, Ifex(R), etoposide, VP-16, Vepesid(R), temozolomide, Temodar(R), temsirolimus, CCI-779, Torisel^TM, bevacizumab, rhumab VEGF, Avastin(R), sorafenib, BAY-43-9006, Nexavar(R), surgery, therapeutic conventional surgery, radiation, proton beam radiation therapy, external beam radiation therapy, brachytherapy
St. Jude Children's Research Hospital, University of Tennessee, University of Florida, Nemours Children's Clinic
Desmoplastic Small Round Cell Tumor, Ewing Sarcoma of Bone or Soft Tissue, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
08/15
07/26
2004-002106-29: A Randomized, Multicenter, Open-label Study of YONDELIS ™ (ET-743ecteinascidin) Administered by 2 Different Schedules (Weekly for 3 of 4 weeksvs. q3 Weeks) in Subjects With Locally Advanced or Metastatic Liposarcomaor Leiomyosarcoma Following Treatment With an Anthracycline andIfosfamide

 
2
12
Europe
YONDELIS (trabectedin), ET-743; R279741; RWJ-680581,
Pharma Mar SA Unipersonal, PHARMA MAR
Advanced or Metastatic Liposarcoma or Leiomyosarcoma
 
05/08
2008-003316-36: NON PEGILATED LIPOSOMIAL DOXORUBICIN (TLC D-99) IN ASSOCIATION WITH IFOSFAMIDE IN PATIENTS WITH METASTATIC SOFT TISSUE SARCOMA

Ongoing
2
32
Europe
MYOCET, HOLOXAN*EV 1FL 1G, MYOCET, HOLOXAN*EV 1FL 1G
CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO
METASTATIC SOFT TISSUE SARCOMAS
 
 
NCT01055314: Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Checkmark ASCO 2015
May 2015 - May 2015: ASCO 2015
Completed
2
175
US, Canada, RoW
Cixutumumab, Anti-IGF-1R Recombinant Monoclonal Antibody IMC-A12, IMC-A12, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, Dactinomycin, Actinomycin A IV, Actinomycin C1, ACTINOMYCIN D, Actinomycin I1, Actinomycin IV, Actinomycin X 1, Actinomycin-[thr-val-pro-sar-meval], Cosmegen, DACT, Dactinomycine, Lyovac Cosmegen, Meractinomycin, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16-213, VP-16, VP-16-213, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Irinotecan Hydrochloride, Campto, Camptosar, Camptothecin 11, Camptothecin-11, CPT 11, CPT-11, U-101440E, Laboratory Biomarker Analysis, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temodal, Temodar, Vincristine Sulfate Liposome, Marqibo
National Cancer Institute (NCI)
Adult Rhabdomyosarcoma, Childhood Alveolar Rhabdomyosarcoma, Childhood Embryonal Rhabdomyosarcoma, Metastatic Childhood Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma, Untreated Childhood Rhabdomyosarcoma
06/16
06/16
NCT02207309 / 2013-000522-58: Pazopanib Maintenance Phase II

Terminated
2
1
Europe
Pazopanib, Votrient, Placebo (for Pazopanib)
Ludwig-Maximilians - University of Munich
Sarcoma
07/16
07/16
MEMOS, NCT02441309 / 2012-000615-84: A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma

Terminated
2
8
Europe
Mifamurtide, Ifosfamide
University of Oxford, Millennium: The Takeda Oncology Company, National Institute for Health Research, United Kingdom, Oxford University Hospitals NHS Trust, European Commission
Osteosarcoma
11/16
11/16
NCT02050919: Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma

Completed
2
20
US
Epirubicin Hydrochloride, Ellence, IMI-28, Pharmorubicin PFS, External Beam Radiation Therapy, Definitive Radiation Therapy, EBRT, External Beam Radiotherapy, External Beam RT, external radiation, External Radiation Therapy, external-beam radiation, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Sorafenib Tosylate, BAY 43-9006 Tosylate, BAY 54-9085, Nexavar, sorafenib, Therapeutic Conventional Surgery
OHSU Knight Cancer Institute, Bayer, Oregon Health and Science University
Pleomorphic Rhabdomyosarcoma, Stage IIB Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7, Stage IV Adult Soft Tissue Sarcoma AJCC v7
05/18
12/20
NCT02812654: Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Sarcoma Treatment

Unknown status
2
70
RoW
Doxorubicin, Adriamycin, Ifosfamide, Mitoxana, radiotherapy
AC Camargo Cancer Center
Sarcoma, Soft Tissue
12/18
03/19
OsteoREC2015, NCT02718482 / 2015-004762-28: Phase II Trial for the Treatment of Relapsed Osteosarcoma

Terminated
2
7
Europe
Gemcitabine and Docetaxel, Ifosfamide, High doses ifosfamide
Italian Sarcoma Group
OSTEOSARCOMA
01/19
01/19
UN-RESARC, NCT03651375: Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall

Active, not recruiting
2
46
Europe
Sequential chemotherapy - 3 courses of AI, Hypofractionated radiotherapy
Maria Sklodowska-Curie National Research Institute of Oncology
Sarcoma, Fibrosarcoma, Leiomyosarcoma, Liposarcoma, Myosarcoma, Histiocytic Sarcoma, Synovial Sarcoma, Lymphangiosarcoma, Malignant Peripheral Nerve Sheath Tumors, Myxofibrosarcoma, Myxoid Liposarcoma, Undifferentiated Sarcoma, Pleomorphic Liposarcoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, Pleomorphic Rhabdomyosarcoma, Malignant Triton Tumor
12/19
03/22
ALTER-S005, NCT03815474: Anlotinib Hydrochloride Combined With Epirubicin and Ifosfamide for Soft Tissue Sarcoma Patients

Unknown status
2
47
RoW
anlotinib, epirubicin ifosfamide
Liaoning Tumor Hospital & Institute, First Hospital of China Medical University, Dalian Municipal Central Hospital, The Second Affiliated Hospital of Dalian Medical University, China-Japan Friendship Hospital, The Third Affiliated Hospital of Harbin Medical University, Second Hospital of Jilin University, Daqing Oil Field Hospital
Sarcoma, Soft Tissue
12/19
12/20
NCT04126811: Apatinib Combined With Chemotherapy in the Treatment of Soft Tissue Sarcoma

Unknown status
2
120
RoW
Apatinib Mesylate, Pirarubicin, Ifosfamide, Apatinib Mesylate, Pirarubicin, Ifosfamide
Tianjin Medical University Cancer Institute and Hospital
Soft Tissue Sarcoma
12/19
12/20
NCT02784015: Response Based Treatment for Children With Unresectable Localized Soft Tissue Sarcoma

Recruiting
2
41
RoW
Cisplatin, Etoposide, Doxorubicin, Cyclophosphamide, Ifosfamide, Carboplatin, Radiotherapy, Thiotepa, Melphalan
Samsung Medical Center
Unresectable Localized Soft Tissue Sarcoma
05/20
05/23
NCT02732015: Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy

Terminated
2
37
US
Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycadron, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decadron DP, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasone Intensol, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Fluorodelta, Fortecortin, Gammacorten, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, TaperDex, Visumetazone, ZoDex, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Fosaprepitant Dimeglumine, Emend for Injection, L-785,298, MK-0517, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Mesna, 2-Mercaptoethanesulfonate, Sodium Salt, Ausobronc, D-7093, Filesna, Mercaptoethane Sulfonate, Mercaptoethanesulfonate, Mesnex, Mesnil, Mesnum, Mexan, Mistabron, Mistabronco, Mitexan, Mucofluid, Mucolene, UCB 3983, Uromitexan, Ziken, Ondansetron, Zofran ODT, Zuplenz, Questionnaire Administration, Rolapitant Hydrochloride, Rolapitant HCl, Rolapitant Hydrochloride Monohydrate, Rolapitant Monohydrochloride Monohydrate, SCH-619734, SCH619734, Varubi, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Locally Advanced Sarcoma
07/20
07/20
2020-002777-95: Sequential neoadjuvant ifosfamide and doxorubicin in localized high-grade soft tissue sarcoma of extremities and trunk wall

Not yet recruiting
2
50
Europe
Ifosfamide, Doxorubicin, Powder for concentrate for solution for injection/infusion, Injection, Holoxan, Adriamycin
Oslo University Hospital, Tildelte forskningsmidler
Soft Tissue Sarcoma, Cancer, Diseases [C] - Cancer [C04]
 
 
ANITA, NCT02808247 / 2016-002093-12: Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma

Terminated
2
80
Europe
Nintedanib, BIBF1120, Ifosfamide
European Organisation for Research and Treatment of Cancer - EORTC, Boehringer Ingelheim
Sarcoma, Soft Tissue
11/20
04/21
NCT03268772: PLD and IFO As First-line Treatment for Patients With Advanced or Metastatic STS

Unknown status
2
40
RoW
PLD and IFO
Fudan University
Soft Tissue Sarcoma
11/20
12/20
NCT03711279: A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma

Terminated
2
99
RoW
SHR-1210 plus Apatinib, PD-1 antibody + Anti-angiogenesis, ADM plus IFO or IFO alone, chemotherapy
Jiangsu HengRui Medicine Co., Ltd.
Sarcoma
06/21
06/21
ChiCTR1800016587: Comparison of efficacy between GD and IE as second-line chemotherapy regimens in advanced soft tissue sarcoma: a phase II randomized controlled trial

Not yet recruiting
2
266
 
Gemcitabine with Docetaxel ;Ifosfamide with Etoposide
West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self financing
soft tissue sarcoma
 
 
2021-001085-37: Bintrafusp alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma. Chimiothérapie néo-adjuvante plus retifanlimab (INCMGA00012)chez les patients porteurs de sarcomes rétropéritoneaux sélectionnés : une étude randomisée de phase II.

Not yet recruiting
2
66
Europe
Retifanlimab, DOXORUBICIN, HOLOXAN, INCMGA00012, Solution for infusion, Powder for infusion, DOXORUBICIN, HOLOXAN (Ifosfamide)
Institut Bergonié, Incyte Biosciences International Sarl
retroperitoneal sarcomas sarcomes rétropéritonéaux, retroperitoneal sarcomas sarcomes rétropéritonéaux, Diseases [C] - Cancer [C04]
 
 
NCT04224337: Phase II Study of Durvalumab ,Doxorubicin, and Ifosfamide in Pulmonary Sarcomatoid Carcinoma

Active, not recruiting
2
34
RoW
Durvalumab + doxorubicin + ifosfamide
Seoul National University Hospital
Carcinoma, Non-Small-Cell Lung
08/23
05/25
NCT01979393 / 2013-000762-11: IRCI Gynae Sarcomas, High Grade Uterine Sarcoma

Active, not recruiting
2
58
Europe
Cabozantinib, Placebo
European Organisation for Research and Treatment of Cancer - EORTC, Gynecologic Oncology Group, NHS Greater Glasgow and Clyde
Uterine Sarcoma
03/22
05/24
SAIS, NCT04356872: The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma

Recruiting
2
45
RoW
Sintilimab, Doxorubicin Hydrochloride, ADM, Ifosfamide, IFO
Fudan University, Zhejiang Cancer Hospital, Tongji Hospital, Xijing Hospital, Shanghai Zhongshan Hospital
Sarcoma, Soft Tissue
03/22
03/23
AIEOP EW-2, NCT02727387: Protocol for the Treatment of Metastatic Ewing Sarcoma

Completed
2
155
Europe
TEMIRI, Temozolomide + Irinotecan, ADM, Adriamycin, IFO, Ifosfamide, CYC, Cyclophosphamide, ETO, Etoposide, BUMEL, busulfan + melphalan, VIN, Vincristine
Italian Sarcoma Group
Ewing's Sarcoma (ES)
04/22
04/22
NCT04154189 / 2019-003696-19: A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

Completed
2
81
Europe, Canada, US, RoW
Lenvatinib, E7080, Ifosfamide, Etoposide
Eisai Inc., Merck Sharp & Dohme LLC
Osteosarcoma
06/22
08/23
ChiCTR1900025067: A prospective, open, single-center, non-randomized controlled trial for Anlotinib hydrochloride versus AI chemotherapy in the treatment of soft tissue sarcoma

Not yet recruiting
2
61
 
doxorubicin+ifosfamide ;Anlotinib hydrochloride, p.o.
Guangxi Medical University Cancer Hospital; Guangxi Medical University Cancer Hospital, CHIA TAI TIANQING (CTTQ) Pharmaceutical Co., Ltd.
Soft Tissue Sarcoma
 
 
AIEO, NCT04824352: Apatinib Plus IE Chemotherapy (Ifosfamide and Etoposide) for Relapsed or Refractory Osteosarcoma

Suspended
2
44
RoW
apatinib, IE chemotherapy
Peking University People's Hospital, Peking University Shougang Hospital
Effect of Drug, Toxicity, Drug
04/26
04/26
2023-000169-14: Clinical Study of High-Dose Treosulfan/Melphalan as Consolidation Treatment in Newly Diagnosed High-Risk and Very High-Risk Ewing Sarcoma Studio clinico su Treosulfan/Melfalan ad alte dosi come trattamento di consolidamento nel sarcoma di Ewing ad alto e altissimo rischio di nuova diagnosi

Not yet recruiting
2
60
Europe
Trecondi, Vincristina, Cyclophosphamide, Doxorubicin, Ifosfamide, Etoposide, Melphalan, Powder for solution for infusion, Solution for injection, Powder for injection, Concentrate for solution for infusion, Powder and solvent for solution for injection/infusion, TRECONDI 1 g, TRECONDI 5 g
Fondazione Santobono Pausilipon ONLUS, Medac Gesellschaft für klinische Spezialpräparate m.b.H.,
Ewing Sarcoma Sarcoma di Ewing, Ewing sarcoma, a bone tumor affecting children, adolescents and young adults Sarcoma di Ewing, un tumore osseo che colpisce bambini, adolescenti e giovani adulti, Diseases [C] - Cancer [C04]
 
 
NCT04012827: Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue Sarcoma

Recruiting
2
108
RoW
Apatinib Mesylate, doxorubicin, ifosfamide, Apatinib
Sun Yat-sen University, Jiangsu HengRui Medicine Co., Ltd.
Soft Tissue Sarcoma
06/23
12/23
OAIE, NCT05277480: Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma

Completed
2
81
RoW
Apatinib+IE, IE
Peking University People's Hospital, Jiangsu HengRui Medicine Co., Ltd.
Effect of Drug, Drug, Toxicity
06/23
11/23
ISG/OS-2, NCT01459484 / 2011-001659-36: ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma

Completed
2
225
Europe
Mifamurtide arm, Methotrexate, Cisplatinum, doxorubicin, ifosfamide, mifamurtide, 3 drugs arm, methotrexate, cisplatin, doxorubicine
Italian Sarcoma Group
Osteosarcoma
04/24
04/24
NCT04589754: Adriamycin and Ifosfamide Combined With Sintilimab

Recruiting
2
176
RoW
Sintilimab plus chemotherapy, Adriamycin-based chemotherapy
Sun Yat-sen University
Soft Tissue Sarcoma
12/25
07/26
NCT06277154: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

Not yet recruiting
2
148
RoW
MASCT-I, Doxorubicin, Doxorubicin hydrochloride for Injection, Ifosfamide, Ifosfamide for Injection
HRYZ Biotech Co.
Leiomyosarcoma, Liposarcoma, Synovial Sarcoma, Angiosarcoma, Undifferentiated Pleomorphic Sarcoma, Epithelioid Sarcoma, Malignant Peripheral Nerve Sheath Tumors, Fibrosarcoma, Pleomorphic Rhabdomyosarcoma, Endometrial Stromal Sarcoma, Desmoplastic Small Round Cell Tumor
02/26
02/27
NCT04776525: Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma

Recruiting
2
49
Europe
Ifosfamide, Holoxan, Doxorubicin, Adriamycin
Oslo University Hospital, Haukeland University Hospital
Soft Tissue Sarcoma
09/26
09/36
NCT00077285: Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma

Active, not recruiting
2
65
US
filgrastim, carboplatin, cyclophosphamide, dexrazoxane hydrochloride, doxorubicin hydrochloride, etoposide, ifosfamide, irinotecan hydrochloride, vincristine sulfate, conventional surgery, radiation therapy
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Sarcoma
10/24
10/24
TORNADO, NCT04968106: Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas

Recruiting
2
66
Europe
Doxorubicin, Ifosfamide, INCMGA00012, Retifanlimab
Institut Bergonié, Incyte Biosciences International Sàrl
Resectable Sarcoma
03/25
10/27
RMS13, NCT01871766: Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active, not recruiting
2
98
US
Vincristine, Oncovin®, Dactinomycin, Actinomycin-D, Cosmegen®, Cyclophosphamide, Cytoxan(R), Surgical Resection, Surgery, Radiation, Proton Beam Radiation, External Beam Radiation, Brachytherapy, Bevacizumab, rhuMab, VEGF, Avastin®, Sorafenib, Nexavar®, Myeloid Growth Factor, G-CSF, Filgrastim, Pegfilgrastim, Lymph Node Sampling, Irinotecan, Camptosar ®, Ifosfamide, Ifex ®, Etoposide, VP-16, Vepesid®, Etoposide Phosphate, Etopophos®, Doxorubicin, Adriamycin®, Dexrazoxane, Zinecard, ^1^1C-methionine, Contrast Media
St. Jude Children's Research Hospital
Rhabdomyosarcoma
07/25
06/30
NCT01864109: Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Active, not recruiting
2
83
US
Cyclophosphamide, Doxorubicin, Vincristine, Ifosfamide, Etoposide, Surgery, Radiation Therapy*, Temozolomide, Irinotecan, Mesna, Dexrazoxane, G-CSF
Memorial Sloan Kettering Cancer Center
Newly Diagnosed Ewing Sarcoma
 
 
NCT00023738: Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma

Completed
1/2
US, Canada
filgrastim, dacarbazine, doxorubicin hydrochloride, ifosfamide, semaxanib, conventional surgery, radiation therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI)
Sarcoma
 
10/03
NCT00187109: Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

Completed
1/2
40
US
Recombinant Human Thrombopoietin
St. Jude Children's Research Hospital
Germ Cell Tumors, Hepatic Cancer, Neuroblastoma, Osteosarcoma, Rhabdomyosarcoma
02/07
02/07
NCT00093509: MRI Sarcoma Non Invasive Thermometry

Completed
1/2
15
US
doxorubicin hydrochloride, Adriamycin, ifosfamide and mesna, Ifosfamide - Ifex, Mesna - sodium 2-mercapto-ethanesulphonate, hyperthermia treatment with an MRI Compatible Radiofrequency Extremity Hyperthermia Applicator, radiation therapy
Mark Dewhirst, National Cancer Institute (NCI)
Sarcoma
07/07
10/09
NCT00541840 / 2007-002176-34: Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma

Unknown status
1/2
24
Europe
Sorafenib, BAY 43-9006
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma
04/09
04/10
NCT00289809 / 2005-004569-40: TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients

Completed
1/2
36
Europe
combination of TLC D-99 and Ifosfamide
Istituto Clinico Humanitas
Sarcoma, Soft Tissue
12/09
12/09
NCT00788125: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Terminated
1/2
7
US
carboplatin, dasatinib, etoposide phosphate, ifosfamide, microarray analysis, western blotting, immunohistochemistry staining method, laboratory biomarker analysis, therapeutic conventional surgery, radiation therapy
City of Hope Medical Center, National Cancer Institute (NCI)
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Kidney Cancer, Liver Cancer, Lymphoma, Neuroblastoma, Ovarian Cancer, Sarcoma, Testicular Germ Cell Tumor, Unspecified Childhood Solid Tumor, Protocol Specific
04/10
07/22
NCT02235701: Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma

Completed
1/2
70
US
170 mg/m2 aldoxorubicin, 250 mg/m2 aldoxorubicin
ImmunityBio, Inc.
Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcoma
05/18
05/18
NCT02432274 / 2013-005534-38: Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

Hourglass Jul 2018 - Sep 2018 : Enrollment completion for P1b/2 study for 2L/3L RCC
Completed
1/2
117
Europe, US
Lenvatinib, E7080, lenvatinib, Ifosfamide, Etoposide
Eisai Limited, Merck Sharp & Dohme LLC
Tumors, Solid Malignant Tumors, Osteosarcoma, Differentiated Thyroid Cancer (DTC)
07/19
07/22
NCT04044378: Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma

Withdrawn
1/2
0
RoW
Famitinib, Ifosfamide, Camrelizumab, camralizumab
Peking University People's Hospital, Peking University Shougang Hospital, Jiangsu HengRui Medicine Co., Ltd.
Effect of Drugs, Progression, Pediatric Cancer
09/21
09/22
NCT06239272: NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Recruiting
1/2
139
US
Surgical resection, Proton beam radiation therapy, Pazopanib, VOTRIENT®, Ifosfamide, Ifex, Doxorubicin, Adriamycin®, Rubex®, Selinexor, XPOVIO®
St. Jude Children's Research Hospital
Non-rhabdomyosarcoma, Adipocytic Neoplasm, Liposarcoma
06/34
06/37
ImmunoSarc, NCT03277924 / 2016-004040-10: Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Recruiting
1/2
270
Europe
Sunitinib 37.5 MG, Sunitinib 25 MG [Sutent], Sutent, Nivolumab 100 MG/10 ML [Opdivo], Opdivo, Epirubicin, Ifosfamide, Doxorubicin, Dacarbazine, Cisplatin, Methotrexate
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma, Bone Sarcoma
06/25
06/25
NCT05813327: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Recruiting
1/2
35
US
ADI PEG20, PEGylated arginine deiminase, Ifosfamide, ifex, Radiotherapy, Mesna, sodium 2-mercaptoethane sulfonate
Washington University School of Medicine, Polaris Group
Soft Tissue Sarcoma, Sts, Sarcoma,Soft Tissue
01/26
01/28
NCT05590572: A Study of Sulfatinib on Relapsed or Refractory Drug Resistant Osteosarcoma

Not yet recruiting
1/2
148
RoW
Sulfatinib, Etoposide, Isophosphamide
Second Affiliated Hospital, School of Medicine, Zhejiang University, Chonnam National University, Peking University People's Hospital, Qilu Hospital of Shandong University, Ruijin Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Osteosarcoma
12/26
12/27
FaR-RMS, NCT04625907 / 2018-000515-24: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma

Recruiting
1/2
1672
Europe, RoW
Irinotecan, Actinomycin D, Dactinomycin, Doxorubicin, Ifosfamide, Vincristine, Vinorelbine, Cyclophosphamide, Temozolomide, radiotherapy, Regorafenib
University of Birmingham
Rhabdomyosarcoma
06/30
06/30

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