Sarcoma  >>  ifosfamide  >>  Phase 2
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18 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ifosfamide / Generic mfg.
NCT00145639: Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma

Completed
2
80
US, RoW
Ifosfamide, Carboplatin, Doxorubicin, Limb Sparing
St. Jude Children's Research Hospital, Immunex/Berlex, National Institutes of Health (NIH)
Osteosarcoma
05/06
05/06
NCT00060944: A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

Completed
2
271
US, Canada, Europe, RoW
Yondelis, Dexamethasone
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., PharmaMar
Liposarcoma, Leiomyosarcoma
05/08
05/08
NCT00667342: A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

Completed
2
43
US
Bevacizumab, rhuMAb VEGF, Avastin®, Cisplatin, Platinol-AQ®, Doxorubicin, Adriamycin®, Methotrexate, MTX, Ifosfamide, Ifex®, etoposide, VP-16, Vepesid®, Surgery, Radiotherapy
St. Jude Children's Research Hospital, Genentech, Inc.
Osteosarcoma, Malignant Fibrous Histiocytoma (MFH) of Bone
08/14
08/17
MEMOS, NCT02441309 / 2012-000615-84: A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma

Terminated
2
8
Europe
Mifamurtide, Ifosfamide
University of Oxford, Millennium: The Takeda Oncology Company, National Institute for Health Research, United Kingdom, Oxford University Hospitals NHS Trust, European Commission
Osteosarcoma
11/16
11/16
NCT02050919: Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma

Completed
2
20
US
Epirubicin Hydrochloride, Ellence, IMI-28, Pharmorubicin PFS, External Beam Radiation Therapy, Definitive Radiation Therapy, EBRT, External Beam Radiotherapy, External Beam RT, external radiation, External Radiation Therapy, external-beam radiation, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Sorafenib Tosylate, BAY 43-9006 Tosylate, BAY 54-9085, Nexavar, sorafenib, Therapeutic Conventional Surgery
OHSU Knight Cancer Institute, Bayer, Oregon Health and Science University
Pleomorphic Rhabdomyosarcoma, Stage IIB Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7, Stage IV Adult Soft Tissue Sarcoma AJCC v7
05/18
12/20
ANITA, NCT02808247 / 2016-002093-12: Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma

Terminated
2
80
Europe
Nintedanib, BIBF1120, Ifosfamide
European Organisation for Research and Treatment of Cancer - EORTC, Boehringer Ingelheim
Sarcoma, Soft Tissue
11/20
04/21
NCT03711279: A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma

Terminated
2
99
RoW
SHR-1210 plus Apatinib, PD-1 antibody + Anti-angiogenesis, ADM plus IFO or IFO alone, chemotherapy
Jiangsu HengRui Medicine Co., Ltd.
Sarcoma
06/21
06/21
2021-001085-37: Bintrafusp alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma. Chimiothérapie néo-adjuvante plus retifanlimab (INCMGA00012)chez les patients porteurs de sarcomes rétropéritoneaux sélectionnés : une étude randomisée de phase II.

Not yet recruiting
2
66
Europe
Retifanlimab, DOXORUBICIN, HOLOXAN, INCMGA00012, Solution for infusion, Powder for infusion, DOXORUBICIN, HOLOXAN (Ifosfamide)
Institut Bergonié, Incyte Biosciences International Sarl
retroperitoneal sarcomas sarcomes rétropéritonéaux, retroperitoneal sarcomas sarcomes rétropéritonéaux, Diseases [C] - Cancer [C04]
 
 
NCT04154189 / 2019-003696-19: A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

Completed
2
81
Europe, Canada, US, RoW
Lenvatinib, E7080, Ifosfamide, Etoposide
Eisai Inc., Merck Sharp & Dohme LLC
Osteosarcoma
06/22
08/23
2023-000169-14: Clinical Study of High-Dose Treosulfan/Melphalan as Consolidation Treatment in Newly Diagnosed High-Risk and Very High-Risk Ewing Sarcoma Studio clinico su Treosulfan/Melfalan ad alte dosi come trattamento di consolidamento nel sarcoma di Ewing ad alto e altissimo rischio di nuova diagnosi

Not yet recruiting
2
60
Europe
Trecondi, Vincristina, Cyclophosphamide, Doxorubicin, Ifosfamide, Etoposide, Melphalan, Powder for solution for infusion, Solution for injection, Powder for injection, Concentrate for solution for infusion, Powder and solvent for solution for injection/infusion, TRECONDI 1 g, TRECONDI 5 g
Fondazione Santobono Pausilipon ONLUS, Medac Gesellschaft für klinische Spezialpräparate m.b.H.,
Ewing Sarcoma Sarcoma di Ewing, Ewing sarcoma, a bone tumor affecting children, adolescents and young adults Sarcoma di Ewing, un tumore osseo che colpisce bambini, adolescenti e giovani adulti, Diseases [C] - Cancer [C04]
 
 
NCT04012827: Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue Sarcoma

Recruiting
2
108
RoW
Apatinib Mesylate, doxorubicin, ifosfamide, Apatinib
Sun Yat-sen University, Jiangsu HengRui Medicine Co., Ltd.
Soft Tissue Sarcoma
06/23
12/23
OAIE, NCT05277480: Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma

Completed
2
81
RoW
Apatinib+IE, IE
Peking University People's Hospital, Jiangsu HengRui Medicine Co., Ltd.
Effect of Drug, Drug, Toxicity
06/23
11/23
NCT06277154: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

Not yet recruiting
2
148
RoW
MASCT-I, Doxorubicin, Doxorubicin hydrochloride for Injection, Ifosfamide, Ifosfamide for Injection
HRYZ Biotech Co.
Leiomyosarcoma, Liposarcoma, Synovial Sarcoma, Angiosarcoma, Undifferentiated Pleomorphic Sarcoma, Epithelioid Sarcoma, Malignant Peripheral Nerve Sheath Tumors, Fibrosarcoma, Pleomorphic Rhabdomyosarcoma, Endometrial Stromal Sarcoma, Desmoplastic Small Round Cell Tumor
02/26
02/27
TORNADO, NCT04968106: Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas

Recruiting
2
66
Europe
Doxorubicin, Ifosfamide, INCMGA00012, Retifanlimab
Institut Bergonié, Incyte Biosciences International Sàrl
Resectable Sarcoma
03/25
10/27
NCT02235701: Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma

Completed
1/2
70
US
170 mg/m2 aldoxorubicin, 250 mg/m2 aldoxorubicin
ImmunityBio, Inc.
Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcoma
05/18
05/18
NCT02432274 / 2013-005534-38: Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

Hourglass Jul 2018 - Sep 2018 : Enrollment completion for P1b/2 study for 2L/3L RCC
Completed
1/2
117
Europe, US
Lenvatinib, E7080, lenvatinib, Ifosfamide, Etoposide
Eisai Limited, Merck Sharp & Dohme LLC
Tumors, Solid Malignant Tumors, Osteosarcoma, Differentiated Thyroid Cancer (DTC)
07/19
07/22
NCT04044378: Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma

Withdrawn
1/2
0
RoW
Famitinib, Ifosfamide, Camrelizumab, camralizumab
Peking University People's Hospital, Peking University Shougang Hospital, Jiangsu HengRui Medicine Co., Ltd.
Effect of Drugs, Progression, Pediatric Cancer
09/21
09/22
NCT05813327: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Recruiting
1/2
35
US
ADI PEG20, PEGylated arginine deiminase, Ifosfamide, ifex, Radiotherapy, Mesna, sodium 2-mercaptoethane sulfonate
Washington University School of Medicine, Polaris Group
Soft Tissue Sarcoma, Sts, Sarcoma,Soft Tissue
01/26
01/28

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