| ledipasvir/sofosbuvir / Generic mfg. |
2013-002296-17: An international study to assess the safety and efficacy of a combination of new investigational drugs in patients with chronic hepatitis C virus infection who have previously failed treatment. |
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| Not yet recruiting | 2 | 150 | Europe | Sofosbuvir/GS-5885 FDC, Ribasphere, GS-7977/GS-5885 FDC, Film-coated tablet, Ribasphere Tablets | Gilead Sciences, Inc., Gilead Sciences Inc | Chronic Genotype 1 Hepatitis C Virus Infection Adultes présentant une infection chronique par le virus de l’hépatite C (VHC) de génotype 1 et une cirrhose, et précédemment traités par un inhibiteur de protéase avec PEG+RBV., Hepatitis C Virus Infection Infection chronique par le virus de l'hépatite C de génotype 1 (correspondant à une variété du virus) chez des patients ayant déjà reçu un traitement pour cette maladie., Diseases [C] - Virus Diseases [C02] | | | | |
2013-003978-27: A study to assess the safety and efficacy of a combination of Sofosbuvir/Ledipasvir in patients with Chronic Genotype 4 or 5 hepatitis C Infection. |
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| Not yet recruiting | 2 | 80 | Europe | SOF/LDV FDC, GS-7977/GS-5885 FDC, Film-coated tablet | Gilead Sciences, Inc., Gilead Sciences Inc | Chronic Genotype 4 and Genotype 5 Hepatitis C Virus Infection, Hepatitis C Virus Infection, Diseases [C] - Virus Diseases [C02] | | | | |
2015-002401-10: Pilot multicenter open label study on treatment with Sofosbuvir/Ledipasvir FDC for patients with thalassemia major and HCV infection. Studio pilota multicentrico con LDV/SOF in pazienti con talassemia major e infezione cronica da HCV |
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| Ongoing | 2 | 100 | Europe | HARVONI, 700016355, Film-coated tablet, HARVONI - 90 MG/400 MG - COMPRESSE RIVESTITE CON FILM - USO ORALE - FLACONE (HDPE) - 28 COMPRESSE RIVESTITE CON FILM | FONDAZIONE CASA SOLLIEVO DELLA SOFFERENZA OPERA DI SAN PIO DA PIETRELCINA OSPEDALE IRCCS, IRCCS CASA SOLLIEVO DELLA SOFFERENZA | Patients with thalassemia major and HCV infection either naïve or on nucleo(s)tide analogs treatment, data on Sofosbuvir-based treatment are currently lacking, while, due to the long infection duration, this category of patients has a urgent treatment need. Pazienti con talassemia major e infezione cronica da HCV di genotipo ¼ (naïve o precedentemente trattati senza successo), Patients with thalassemia major and HCV infection either naïve or on nucleo(s)tide analogs treatment, data on Sofosbuvir-based treatment are currently lacking, while, due to the long infection duratio Pazienti con talassemia major e infezione cronica da HCV di genotipo ¼ (naïve o precedentemente trattati senza successo), Diseases [C] - Virus Diseases [C02] | | | | |
| Ongoing | 2 | 408 | Europe | Viekirax, Exviera (Dasabuvir), Harvoni, Ribavirin (film-coated 200mg), Ribavirin (hard capsule, 200mg), Ribavirin (film-coated, 400mg), Maviret, Film-coated tablet, , Viekirax, Exviera (Dasabuvir), Harvoni, Maviret | Imperial College London, NIHR Efficacy and Mechanism Evaluation Programme | Hepatitis C Infection (HCV) (genotype 1a/1b/4), Hepatitis C infection, Diseases [C] - Virus Diseases [C02] | | | | |
| Completed | 2 | 40 | Europe | Ledipasvir+Sofosbuvir, Harvoni, Sofosbuvir+Velpatasvir, Epclusa | Fondazione Italiana Linfomi ONLUS | Indolent B-cell Lymphoma, Hepatitis C | 02/20 | 11/22 | | |
| Recruiting | 2 | 160 | RoW | PR4 + LDV/SOF + ASV 4 wk, Pegasys®, Copegus®, Harvoni®, Sunvepra®, PR4 + LDV/SOF + SMV 4 wk, OLYSIO®, PR4 + LDV/SOF + ASV 6 wk, PR4 + LDV/SOF + SMV 6 wk, PR4 + LDV/SOF + ASV 8 wk, PR4 + LDV/SOF + SMV 8 wk, PR4 + LDV/SOF + ASV 12 wk, PR4 + LDV/SOF + SMV 12 wk | Humanity and Health Research Centre, Beijing 302 Hospital, Nanfang Hospital of Southern Medical University | Chronic Hepatitis C Infection | 10/22 | 12/22 | | |
NCT03903185: Pharmacokinetics of Ledipasvir/Sofosbuvir in Hepatitis C Virus-Infected Children With Hematological Malignancy |
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| Completed | 1/2 | 24 | RoW | Ledipasvir / Sofosbuvir Oral Product, LDV\SOF | Ain Shams University, Cairo University | Hepatitis C, Chronic, Hematologic Malignancy | 07/23 | 08/23 | | |
