Caprelsa (vandetanib) / Sanofi  >>  Phase 2
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9 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Caprelsa (vandetanib) / Sanofi
NCT00093392: ZD6474, Carboplatin, and Paclitaxel in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

Recruiting
2
220
US
carboplatin, paclitaxel, vandetanib, placebo
Jonsson Comprehensive Cancer Center, National Cancer Institute (NCI)
Lung Cancer
 
 
NCT00537095 / 2007-001890-27: Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer

Checkmark P2 data (MTC)
Aug 2012 - Aug 2012: P2 data (MTC)
Completed
2
164
Europe
Vandetanib, SAR390530, Placebo
Genzyme, a Sanofi Company
Thyroid Neoplasms
12/09
11/21
2013-001652-36: Evaluation of the efficacy of high throughput genome analysis as a therapeutic decision tool for patients with metastatic breast cancer

Not yet recruiting
2
240
Europe
AZD2014, AZD4547, AZD5363, AZD8931, Selumetinib, Vandetanib, Bicalutamide, Olaparib, AZD6244, ZD6474, AZD 2281, Tablet, Capsule, , CAPRELSA, CASODEX
UNICANCER, Astra Zeneca Laboratories
Patients with metastatic breast cancer in 1st or 2nd line of chemotherapy, breast cancer, Diseases [C] - Cancer [C04]
 
 
2005-003591-38: A phase II, double-blind, placebo controlled, randomised study to assess the efficacy and safety of ZD6474 in combination with Arimidex vs. Arimidex alone in patients with hormone sensitive (ER+ve and/or PR+ve) tumours as 2nd line treatment for advanced breast cancer (ABC)

 
2
20
Europe
ZACTIMA, Arimidex, ZD6474, Arimidex, Arimidex
AstraZeneca AB
Hormone sensitive (ER+ve and/ or PR +ve) advanced breast cancer (ABC)
 
08/06
SAFIR02_Lung, NCT02117167 / 2013-001653-27: - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients

Completed
2
999
Europe
AZD2014, AZD4547, AZD5363, AZD8931, Selumetinib, ARRY-142866, Vandetanib, CAPRELSA, Standard maintenance for squamous NSCLC, Pemetrexed, ALIMTA, Durvalumab, savolitinib, Olaparib, LYNPARZA
UNICANCER, Intergroupe Francophone de Cancerologie Thoracique, Fondation ARC, AstraZeneca
Non-small Cell Lung Cancer Metastatic
12/18
12/23
NCT06482086: Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer

Recruiting
2
75
RoW
Anlotinib, Lenvatinib, Sorafenib, Donafenib, Everolimus, Apatinib, Dabrafenib + Trametinib, Cabozantinib, Vandetanib, Entrectinib, Pralsetinib, Larotrectinib
West China Hospital
Locally Advanced Thyroid Gland Carcinoma
12/24
12/25
NCT02638428: Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy

Recruiting
2
90
RoW
CancerSCAN™, Ifosfamide, Carboplatin, Etoposide, Fludarabine, Cytarabine, Pazopanib, Sorafenib, Axitinib, Crizotinib, Dasatinib, Erlotinib, Everolimus, Imatinib, Ruxolitinib, Vandetanib, Vemurafenib, Trastuzumab
Samsung Medical Center, Ministry of Health, Republic of Korea
Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor, Relapsed Pediatric AML, Refractory Pediatric AML
12/21
12/23
SAFIR02_Breast, NCT02299999: - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer

Active, not recruiting
2
1460
Europe
AZD2014, AZD4547, AZD5363, AZD8931, Selumetinib, ARRY-142866, Vandetanib, CAPRELSA, Bicalutamide, Casodex, Olaparib, Lynparza, Anthracyclines, Doxorubicin, Epirubicin, liposomal doxorubicin, Taxanes, paclitaxel, docetaxel, cyclophosphamide, Novatrex, Imeth, DNA intercalators, capecitabine, 5-FU, gemcitabine, Methotrexate, vinca alkaloids, vinorelbine, vinblastine, vincristine, Platinum based chemotherapies, Platinum, carboplatin, cisplatin, Bevacizumab, Avastin, Mitomycin C, Ametycine, Eribulin, Halaven, MEDI4736
UNICANCER, Fondation ARC, AstraZeneca
Metastatic Breast Cancer
12/22
12/24
2017-002517-64: A trial of tiny beads linked to an anti-cancer drug (vandetanib) injected into liver tumours

Not yet recruiting
1/2
56
Europe
Vandetanib Eluting Radiopaque Bead, BTG-002814, Implant
Biocompatibles UK Ltd, Biocompatibles UK Ltd
Hepatocellular Carcinoma (HCC), Liver Cancer, Diseases [C] - Cancer [C04]
 
 

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