methylprednisolone sodium succinate / Generic mfg.  >>  Phase N/A
Welcome,         Profile    Billing    Logout  

44 Trials

   Remove Filter

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
ACTRN12622001186741: Autologous Stem Cell Transplant in Neuro-Inflammatory diseases other than multiple sclerosis

Not yet recruiting
N/A
5
 
The Alfred- Melbourne, The Alfred-Melbourne
Neuro-Inflammatory disease
 
 
ACTRN12623000321640: Chest hyperinflation and response to steroids and inhaled adrenaline in children with bronchiolitis admitted to intensive care

Not yet recruiting
N/A
211
 
Royal Children's Hospital, Royal Children's Hospital
Bronchiolitis
 
 
ChiCTR-TRC-12002662: Effect of epidural dexamethasone or methylprednisolone on post combined spinal-epidural anesthesia lumbar pain

Completed
N/A
200
 
epidural dexamethasone injection ;epidural methylprednisolone injection
Department of ICU, The third affiliated Hospital of Harbin Medical University; Level of the institution:, None
lumbar pain postoperative
 
 
ChiCTR-ONC-13003666: Long-term Effects of High-dose Intravenous Methylprednisolone Pulse Therapy on Thyroid-associated Ophthalmopathy

Completed
N/A
58
 
high-dose intravenous methylprednisolone pulse (IVMP) therapy
First Affiliated Hospital of Xi’an Jiaotong University School of Medicine; First Affiliated Hospital of Xi’an Jiaotong University School of Medicine, Self-financing
Thyroid-associated ophthalmopathy
 
 
ChiCTR-TRC-12002058: Randomized controlled clinical study of inhale budesonide and inject methylprednisolone in AECOPD patients

Completed
N/A
400
 
inhale budesonide suspension ;inject methylprednisolone sodium succinate
the 3rd affiliated hospital of Anhui Medical University (The 1st hospital of Hefei); the 3rd affiliated hospital of Anhui Medical University, self-raised funds about 60%, about 40% raised by Hefei Medical Association
chronic obstructive pulmonary disease
 
 
ChiCTR-IOR-15005906: Methylprednisolone decreases the duration of rocuronium-induced neuromuscular block

Not yet recruiting
N/A
105
 
Patients received methylprednisolone 40mg intravenously 0.5h prior to surgery ;Patients received methylprednisolone 40mg after induction of anaesthesia ;Patients received normal saline 2ml
Obstetrics and Gynecology Hospital of Fudan University; Obstetrics and Gynecology Hospital of Fudan University, no
anaesthesia
 
 
ChiCTR-BOC-16008999: The role and molecular mechanism of HDAC2 on glucocorticoid resistance formation in sudden sensorineural hearing loss

Recruiting
N/A
125
 
intratympanic methylprednisolone perfusion (0.5ml/day,40mg/ml) ;intravenous methylprednisolone 80mg/day×4day, 40mg/day×3day, 20mg/day×3day ;Not treatment
Nanjing Drum Tower Hosipital, Nanjing University Medical School; Nanjing Drum Tower Hosipital, Nanjing University Medical School, National Science Funds of China
Sudden Sensorineural Hearing Loss
 
 
ChiCTR-OOC-17013447: Diagnosis, treatment and prognosis of thyroid associated ophthalmopathy

Recruiting
N/A
50
 
high-dose intravenous methylprednisolone pulse (IVMP) therapy
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology; Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Self-financing
Thyroid-associated ophthalmopathy
 
 
ChiCTR2000029656: A randomized, open-label study to evaluate the efficacy and safety of low-dose corticosteroids in hospitalized patients with novel coronavirus pneumonia (COVID-19)

Not yet recruiting
N/A
100
 
Standard treatment ;Standard treatment and methylprednisolone for injection
Wuhan Pulmonary Hosptial; Wuhan Pulmonary Hosptial, Emergency Project for 2019-nCoV of Ministry of Science and Technology
novel coronavirus pneumonia (COVID-19)
 
 
Methyl19LGH, NCT04559113: Methylprednisolone in COVID-19 Patients

Recruiting
N/A
200
RoW
Methylprednisolone Injectable Product, solu madrol
Lahore General Hospital
SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)
12/20
12/20
ChiCTR-OOC-17013257: Efficacy evaluation of systemic glucocorticoids in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease in different phenotypes

Not yet recruiting
N/A
1044
 
intravenous use methylprednisolone 40mg qd for 5 days ;observation
West China Hospital, Sichuan University; West China Hospital, Sichuan University, National key research project of China during the 13th five-year plan period
Chronic Obstructive Pulmonary Disease
 
 
ChiCTR2000029386: Effectiveness of glucocorticoid therapy in patients with severe novel coronavirus pneumonia: a randomized controlled trial

Recruiting
N/A
48
 
Methylprednisolone, intravenous injection, 1-2mg/kg·d for 3 days. ;Without any glucocorticoid therapy
Chongqing Public Health Medical Center; Chongqing Public Health Medical Center, Chongqing Science and Technology of Bureau
Novel Coronavirus Pneumonia (COVID-19)
 
 
NCT05793359: Comparison of the Effectiveness of Two Glucocorticoid Regimens for Treatment of Graves' Orbitopathy

Completed
N/A
62
Europe
Methylprednisolone, Urbason
Medical University of Sofia
Graves Ophthalmopathy
02/21
02/21
ChiCTR2100043498: Effect of combined treatment with volatile anesthetics, dexmedetomidine, and methylprednisolone on prognosis in patients undergoing heart valve surgery

Recruiting
N/A
246
 
Intravenous methylprednisolone 120mg at anesthetic induction; Dexmedetomidine infusion at a rate of 0.4ug/kg/h after induction until the end of surgery; Volatile anesthetic to maintain anesthesia. ;Use the same technique to give the same amount or rate of normal saline at the same time point mentioned above, and use total intravenous anesthesia (propofol) throughout the surgery to maintain anesthesia
West China Hospital, Sichuan University; West China Hospital, Sichuan University, self-raised
postoperative recovery and perioperative organ protection
 
 
ChiCTR1800019155: Multi-center clinical study for vestibular conversion and rehabilitation training effect of the idiopathic sudden deafness with vertigo

Not yet recruiting
N/A
180
 
Intravenous methylprednisolone andintratympanic injection ;Intravenous methylprednisolone +intratympanic injection+intravenous of Ginaton ;shock dose hormone group
Eye & ENT Hospital of Fudan University; Eye &ENT Hospital of Fudan University, The 2018 annual science and technology innovation action plan project of Shanghai municipal science and technology commission
the idiopathic sudden deafness with vertigo
 
 
NCT04507165: Opioid-free Anesthesia in VATS Lung Resection

Not yet recruiting
N/A
100
RoW
Paravertebral block+Anterior serratus plane block, nerve block, opioid free anesthesia, OFA, opioid based anesthesia, Standard anesthesia
Peking University People's Hospital
Opioid Free Anesthesia
07/21
07/22
SUCCES, NCT03942861: Sonographic Assessment in Severe Ulcerative Colitis Patients Admitted for Intravenous Corticosteroids and Eligible for Infliximab Rescue Therapy; a Prospective Clinician-blinded Observational Study Protocol.

Recruiting
N/A
50
Europe
Solu-Medrol
Copenhagen University Hospital at Herlev
Ulcerative Colitis, Ultrasound Therapy; Complications
09/21
02/22
NCT06189586: Comparison of Aerosol Inhalation and Intravenous Glucocorticoid in the Treatment of Severe AECOPD

Enrolling by invitation
N/A
100
RoW
aerosol inhalation of glucocorticoids, intravenous injection of glucocorticoids
Dong Yang, Jilin University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
12/24
07/25
NCT04810819: Clinical Study of the Effect of Methylprednisolone Combined

Not yet recruiting
N/A
110
NA
Methylprednisolone 40 MG Injection;Dihydroxypropyltheophylline;, Placebo
Qianfoshan Hospital
Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics
10/21
12/21
NCT03586557: Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic Neuritis

Recruiting
N/A
142
RoW
Corticosteroid & Plasma exchange, CS+PE, Corticosteroid, CS
Chinese PLA General Hospital
Optic Neuritis
12/21
12/21
ChiCTR1800020060: A prospective, randomized, multicenter, controlled trial for the use of glucocorticoids in the treatment of AECOPD through different routes and courses

Not yet recruiting
N/A
480
 
6ml (3mg) Budesonide aerosol inhalation for Bid*5 days ;6ml (3mg) Budesonide aerosol inhalation for Bid*9-14 days ;Methylprednisolone 40 mg intravenous drip or oral prednisolone 40 mg, Qd*5 days ;Methylprednisolone 40 mg intravenous drip or oral prednisolone 40 mg, Qd*9-14 days
Hefei First People's Hospital; Hefei First People's Hospital, Anhui Key Research and Development Plan
Chronic obstructive pulmonary disease
 
 
ChiCTR1900025244: The efficacy and safety of immunomodulatory treatment in HBV-related ACLF

Not yet recruiting
N/A
135
 
common medical treatment, combined with methylprednisolone 40mg intravenously once a day, discontinued after 5 days ;common medical treatment, combined with the Zidaxian 1.6mg subcutaneous injection once a day, discontinued after 5 days. ;Routine medical treatment.
Zhejiang University; The Third Affiliated Hospital, SUN YAT-SEN University, Ministry of Finance,China
HBV-ACLF
 
 
NCT05990894: Steroid for Treatment of Acute/Subacute Severe Cerebral Venous Thrombosis.

Completed
N/A
170
RoW
Methylprednisolone
Xuanwu Hospital, Beijing
Cerebral Venous Thrombosis
07/24
07/24
NCT04808856: Treatment of Refractory Gout With ACTH or Methylprednisolone

Recruiting
N/A
60
RoW
Adrenocorticotropic Hormone, Methylprednisolone Injection
Shanghai 10th People's Hospital
Gout
04/22
04/22
NCT03122847: Glucocorticoids and Bone in Graves' Ophthalmopathy

Active, not recruiting
N/A
30
Europe
Methylprednisolone
Torben Harsløf, Odense University Hospital
Graves Ophthalmopathy
07/22
07/23
ChiCTR1900027528: Prospective observational cohort study on the efficacy of different treatment methods for severe neuroimmune diseases

Not yet recruiting
N/A
390
 
plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;Intravenous immunoglobulin
Department of Neurology, Xiangya Hospital, Central South University; Xiangya Hospital, Central South University, Self-raised
Severe Neuroimmune Disease
 
 
ChiCTR2000038871: Clinical study of batroxobin injection in the treatment of sudden deafness

Recruiting
N/A
210
 
Batroxobin + methylprednisolone intravenous injection ;Methylprednisolone intravenous injection + dexamethasone injection ;Batroxobin + methylprednisolone intravenous injection + dexamethasone tympanic injection
The First Affiliated Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangzhou Medical University, Tinnitus stimulation non-invasive neuromodulation therapy
Sudden deafness
 
 
NCT05455398: Establishment of a Trans-round Window Inner Ear Continuous Drug Delivery System for the Treatment of Severe-to-profound Sudden Sensorineural Hearing Loss

Recruiting
N/A
218
RoW
Surgical treatment of round window niche enlargement via round window for inner ear drug delivery, Drum chamber drug injection
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hearing Loss, Sudden
11/23
03/24
ICOMI, NCT03915223: Soft Part Management for Surgical Fractures of the Lower Limb

Completed
N/A
104
Europe
leg fracture
University Hospital, Clermont-Ferrand
Leg Injuries, Fracture, Edema
12/23
05/24
REVIVES, NCT06203847: The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA

Not yet recruiting
N/A
1200
RoW
Combination group, Standard group
National Taiwan University Hospital
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Emergency Medical Services
06/26
12/26
NCT05842681: Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Not yet recruiting
N/A
30
RoW
Azithromycin, azithromycin 500 mg oral tablet, Methylprednisolone, methylprednisolone 500 mg
Assiut University
Idiopathic Pulmonary Fibrosis
03/24
06/24
ChiCTR2100047811: The relationship between FeNO50 +CANO combined detection and treatment response in patients with acute exacerbation of COPD

Not yet recruiting
N/A
103
 
Intravenous methylprednisolone (40mg/ day) was used for 1-3 days during hospitalization; Intravenous methylprednisolone (40mg/ day) was used for 4-7 days during hospitalization ;No systemic hormones were used during hospitalization
Shenzhen Second People's Hospital; Shenzhen Second People's Hospital, Funding from hospital-level clinical research projects in 2021
chronic obstructive pulmonary disease
 
 
NCT06068829: Inebilizumab and Rituximab in Neuromyelitis Optica Spectrum Disorders

Not yet recruiting
N/A
80
NA
Inebilizumab, Rituximab(RTX)
Feng Jinzhou
Neuromyelitis Optica Spectrum Disorders
06/24
06/25
NCT05964725: The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus

Recruiting
N/A
86
RoW
Receive traditional medical therapy and transcranial direct current stimulation, Receive traditional medical therapy and sham stimulation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method, Female, Male, Human, Treatment Outcome
08/24
08/24
NCT06118398: Efgartigimod in Acute Neuromyelitis Optica Spectrum Disorders

Not yet recruiting
N/A
24
NA
Intravenous methylprednisolone (IVMP) and Efgartigimod, IVMP
Feng Jinzhou
Neuromyelitis Optica, Efgartigimod
11/24
05/25
ChiCTR2400080486: Effect of high-dose methylprednisolone on the early postoperative quality of recovery in patients undergoing minimally invasive esophagectomy: a randomized controlled trial

Not yet recruiting
N/A
218
 
Intravenous methylprednisolone 120 mg before skin incision; An equal volume of saline was administered intravenously prior to skin incision
West China Hospital, Sichuan University; West China Hospital, Sichuan University, None
Esophageal cancer
 
 
ChiCTR2300071734: Effectiveness and safety evaluation of Chinese medicine in the treatment of patients with PPF with phlegm heat-blood stasis obstructing in the lung: a randomized controlled, open-label clinical trial

Not yet recruiting
N/A
50
 
Mahuang, Kuxingren, Gancao, Fengfang, Dilong, Chishao, Jiezi, Laifuzi, Zisuzi, Huangqi, Huangqin, Qinghao ;1. All patients will take pulmonary rehabilitation therapy; 2. Patients with hypoxia at rest, will take long-term oxygen therapy; 3. Patients with pulmonary infection will take empirical anti-infective treatment, and targeted anti-infective treatment will be given after obtaining the results of drug sensitivity test. For the dosage of hormones and immunomodulators, our recommendations are summarised below: (1) Glucocorticoid: the initial dose of glucocorticoid can range from oral prednisone (1mg·kg-1·d-1) to intravenous methylprednisolone (500-1000 mg/d) for 3 days, then reduced to prednisone or equivalent dose, gradually reduced to maintenance dose in 4-8 weeks according to the patient's condition and treatment response, and maintained close follow-up; (2) Cyclophosphamide: adhere to the daily use of 2mg, the initial dose is prescribed daily oral 25mg-50mg, and increase 25mg every other week to two weeks, according to this cycle until the maximum dose reaches the daily 150mg; (3) Azathioprine: administered at 2-3 mg·kg-1·d-1. The initial dose is 25-30mg/d, and then 25mg will be increased every 7 to 14 days until the maximum amount of 150mg/d is reached; In addition, if the subjects had taken oral corticosteroids for more than one month before entering the trial, and the hormone had reached the maintenance dose, or if they had taken oral immunomodulators for more than one month before entering the trial, the original drug treatment regimen should not be changed during the clinical observation, the investigators should record it completely and truthfully.
Hospital of Chengdu University of Traditional Chinese Medicine; Beijing University of Chinese Medicine, National Natural Science Foundation of China (No.81973713)
progressive pulmonary fibrosis(PPF)
 
 
NCT01630850: Islet Transplantation in Patients With "Brittle" Type I Diabetes

Recruiting
N/A
20
US
Allogenic islet cells (human, U. Chicago), Intraportal infusion of islet cells
University of Chicago
Diabetes Mellitus, Type 1
05/25
06/30
ChiCTR2000034214: A multicenter, prospective, cohort study for the efficacy and adverse reactions of ANCA associated glomerulonephritis based on ARRS score

Not yet recruiting
N/A
106
 
Induction remission stage: Glucocorticoid + cyclophosphamide; Maintain remission stage: Hormone + azathioprine / methotrexate / mycophenolate mofetil ;Induction remission stage: Methylprednisolone + intravenous cyclophosphamide or rituximab; Maintain remission stage: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + cyclophosphamide + rituximab + plasma exchange; Maintain: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + intravenous cyclophosphamide; Maintain: Hormone + azathioprine / methotrexate / mycophenolate mofetil
Children's Hospital Affiliated to Chongqing Medical University; Children's Hospital Affiliated to Chongqing Medical University, self-financing
ANCA associated glomerulonephritis
 
 
ChiCTR2200058688: A prospective, single-center, randomized controlled trial of glucocorticoid impulse therapy for acute exacerbation of idiopathic pulmonary fibrosis

Not yet recruiting
N/A
60
 
Methylprednisolone 500mg/qd intravenous for 3 days ;Methylprednisolone 160mg/qd intravenous for 3 days,then taped gradually.
Nanjing Drum Tower Hospital, The Affiliated Nanjing University Medical School; Nanjing Drum Tower Hospital, The Affiliated Nanjing University Medical School, Self-finance
Acute exacerbation of idiopathic pulmonary fibrosis
 
 
NCT05891379: Inebilizumab in Acute Neuromyelitis Optica Spectrum Disorders

Recruiting
N/A
50
RoW
Inebilizumab, oral immunosuppressant
Xuanwu Hospital, Beijing, Jiangsu Hansoh Pharmaceutical Co., Ltd.
Neuromyelitis Optica Spectrum Disorder
07/25
07/25
ScanCLAD, NCT02936505 / 2015-004137-27: Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD.

Active, not recruiting
N/A
249
Europe
Cyclosporine, Sandimmun Neural, Mycophenolate mofetil (MMF), Cellcept, Rabbit Anti thymocyte globulin, Thymoglobulin®, Corticosteroids, Methylprednisolon, Tacrolimus, Advagraf®
Vastra Gotaland Region, Oslo University Hospital, Helsinki University Central Hospital, Skane University Hospital, Copenhagen University Hospital, Denmark
Lung Transplantation, Allografts
10/25
10/26
TEIAS, NCT03924791: Transforaminal Epidural Injection in Acute Sciatica

Recruiting
N/A
142
Europe
Lidocaine, Methylprednisolone Acetate, Depo-Medrol, Dexamethasone
C.L.A.Vleggeert-Lankamp, Spaarne Gasthuis, Stichting Achmea Gezondheidszor, Posthumus Meyjes Fonds
Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
12/25
07/26
ChiCTR2400079564: Evaluation of the clinical effectiveness of hormone therapy alone versus IVIG combined with hormone therapy for second dose IVIG unresponsive Kawasaki disease ---- a multicenter randomized controlled t

Not yet recruiting
N/A
100
 
IVIG+solu-medrol 2mg/kg; solu-medrol 2mg/kg
Shenzhen Children’s Hospital; Shenzhen Children’s Hospital, Special clinical research project of Shenzhen Children's Hospital
Kawasaki Disease
 
 

Download Options