methylprednisolone sodium succinate / Generic mfg. 
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207 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
2005-004180-28: Kan en enkelt dosis steroid nedsætte mængeden af serom efter mastektomi? et randomiseret pilotstudie

Ongoing
2
40
Europe
solu-medrol, Solu-Medrol, Solu-Medrol
Brystkirurgisk afd. F Amtsygehuset i Herlev 18 sal
Seromdannelse efter mastektomi
 
 
2007-000699-18: Randomized phase II study of two associations of rituximab and chemotherapy, with a pet-driven strategy, in patients from 18 to 59 with DLBCL CD20+ lymphoma and 2 or 3 adverse prognostic factors of the age-adjusted IPI

Ongoing
2
222
Europe
PREDNISONE, RITUXIMAB, DOXORUBICINE, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN, METHOTREXATE, G-CSF, VINCRISTINE, IFOSFAMIDE, ETOPOSIDE, CYTARABINE, CARMUSTINE, MELPHALAN, autologous stem cells, Solu-Medrol®, Medrol®, Mabthera 100mg, Mabthera 500mg, ADRIBLASTINA®, ENDOXAN®, BLEOMYCINE®, LEDERTREXATE®, Neupogen®, VINCRISIN®, VEPESID®, HOLOXAN®, Cytosar®, Alkeran®, VORINA®, NITRUMON®, ZEVALIN, Solu-Medrol®, Medrol®, Mabthera 100mg, Mabthera 500mg, ADRIBLASTINA®, ENDOXAN®, BLEOMYCINE®, LEDERTREXATE®, Neupogen®, VINCRISIN®, VEPESID®, HOLOXAN®, Cytosar®, Alkeran®, VORINA®, NITRUMON®, ZEVALIN
Hospices Civils de Lyon, Groupe d\'Etude des Lymphomes de l\'Adulte(GELA)
CD20+ diffuse large B-cell lymphoma
 
 
2017-003564-12: Impact sur la morbidité de l'administration d'une forte dose unique de corticoïdes au moment de l'anesthésie lors d'une chirurgie colorectale

Ongoing
2
109
Europe
Powder for solution for injection, METHYLPREDNISOLONE
CHU Dijon Bourgogne
Chirurgie colorectale élective, Chirurgies du côlon et du rectum, Body processes [G] - Immune system processes [G12]
 
 
2018-000620-34: Imatinib treatment for Multiple Sclerosis (MS) Relapses

Ongoing
2
200
Europe
Solu-Medrol, Film-coated tablet, Injection, Solu-Medrol
Department of Clinical Neuroscience, Karolinska Institutet, Vetenskapsrådet
Patients with clinically definite Multiple Sclerosis (MS) according to the McDonald Criteria, or possible MS (also named clinically isolated syndrome-CIS, as a first manifestation of MS, where there are radiological and/or cerebrospinal fluid signs consistent with MS), which display an acute relapse, Patients with Multiple Sclerosis (MS) with a relapse or with symptoms and signs giving rise to high suspicion of MS with relapse, Diseases [C] - Nervous System Diseases [C10]
 
 
NOBILITY, NCT02550652 / 2015-002022-39: A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)

Checkmark Efficacy and safety data from NOBILITY trial for lupus nephritis
Nov 2020 - Nov 2020: Efficacy and safety data from NOBILITY trial for lupus nephritis
Checkmark Safety and efficacy data from trial for lupus nephritis at ASN/ACR 2019
Nov 2019 - Nov 2019: Safety and efficacy data from trial for lupus nephritis at ASN/ACR 2019
Checkmark Safety and efficacy data from NOBILITY trial in lupus nephritis
More
Completed
2
126
Europe, US, RoW
Mycophenolate Mofetil/Mycophenolic Acid, Obinutuzumab, Gazyva, GA101, RO5072759, Placebo, Methylprednisolone, Prednisone
Hoffmann-La Roche
Lupus Nephritis
01/19
08/23
2018-002790-22: Efficacy evaluation of tocilizumab in the treatment Graves' Orbitopathy Valutazione dell’efficacia di tocilizumab nel trattamento dell’orbitopatia basedowiana

Not yet recruiting
2
64
Europe
Roactemra, SOLU MEDROL, Tocilizumab, SOLU MEDROL, Concentrate for solution for infusion, Powder and solvent for solution for injection, ROACTEMRA - 20 MG/ML CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 4ML 1 FLACONCINO, SOLU MEDROL - 500 MG/8 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE DI POLVERE DA 500 MG+ FIALA SOLVENTE DA 8 ML
FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Roche S.p.A.
Active moderate-severe Graves' Orbitopathy Orbitopatia basedowiana di grado moderato-severo in fase attiva, Garcves' Orbitopathy in the zacute inflammatory phase Oftalmopatia di Basedow in fase infiiammatoria acuta, Diseases [C] - Hormonal diseases [C19]
 
 
2021-000641-41: Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Not yet recruiting
2
70
Europe
Powder and solvent for solution for injection, Tablet, Solu-Medrol, Rapamune
Helse Bergen HF, Haukeland University Hospital, HelseVest
Thyroid Eye Disease (TED) in patients with Graves' Diease., Thyroid Eye Disease (TED) in patients with Graves' Diease., Diseases [C] - Eye Diseases [C11]
 
 
STEROHCA, NCT04624776: Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest

Completed
2
158
Europe
Methylprednisolone, Solu-Medrol, Isotonic saline, Placebo
Christian Hassager
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome, Systemic Inflammatory Response Syndrome, Neurological Injury
07/22
02/23
NCT05134181: Ultrasound Guided Intra-sacroiliac Joint Injection: Methylprednisolone Versus Triamcinolone

Recruiting
2
45
RoW
sacroiliac joint injection
Mansoura University
Sacroiliac Joint Arthritis
08/22
12/22
NCT04903054: Selective CD28 Blockade in Renal Transplant Recipients

Withdrawn
2
54
US
Lulizumab, BMS-931699, anti-CD28 domain antibody (anti-CD28 dAb), Tacrolimus, Prograf®, Thymoglobulin®, antithymocyte globulin, Methylprednisolone, corticosteroid, Mycophenolate Mofetil, MMF, CellCept®, Prednisone
National Institute of Allergy and Infectious Diseases (NIAID), Bristol-Myers Squibb, PPD
Kidney Transplantation, Renal Transplant Recipients
09/22
09/22
NCT03913702: Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement

Terminated
2
1
US
Ketorolac Tromethamine, Toradol, Methylprednisolone Acetate, DepoMedrol
The University of Texas Medical Branch, Galveston
Subacromial Impingement, Subacromial Impingement Syndrome
11/22
11/22
NCT02582775: MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs

Completed
2
17
US
Thymoglobulin, ATG, anti-thymocyte globulin, Cyclophosphamide, Cytoxan, Fludarabine, fludarabine phosphate, Fludara, Total Body Irradiation, TBI, Bone marrow infusion, HCT, Tacrolimus, Prograf, Mycophenolate Mofetil, MMF, Donor mesenchymal stem cell infusions, Busulfan
Masonic Cancer Center, University of Minnesota
Epidermolysis Bullosa
11/22
07/23
TOGO, NCT04876534: Tocilizumab in Active Moderate-severe Graves' Orbitopathy

Recruiting
2
64
Europe
Tocilizumab 20 Mg/mL Intravenous Solution, Actemra, MethylPREDNISolone Injectable Solution, Solumedrol
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Mauriziano Umberto I Hospital, Istituto Auxologico Italiano, Azienda Ospedaliera "Sant'Andrea", Azienda Ospedaliero, Universitaria Pisana
Graves Ophthalmopathy
12/22
12/23
NCT03674099: Imatinib for Multiple Sclerosis (MS) Relapses

Recruiting
2
200
Europe
Imatinib Mesylate, Methylprednisolone
Tomas Olsson, The Swedish Research Council
Multiple Sclerosis
12/22
07/23
NCT04251832: Efficacy of Sodium Thiosulfate in Shoulder Pain in Calcific Tendinitis of the Rotator Cuff

Recruiting
2
80
Europe
Sodium Thiosulfate
Soraia Azevedo
Sodium Thiosulfate, Calcific Tendinitis, Shoulder Pain
12/22
12/22
NCT04061876: First Line Therapy for High Risk Acute GVHD

Completed
2
198
RoW
Ruxolitinib, New, Corticosteroid, Traditional
Chinese PLA General Hospital, LU DAOPEI MEDICAL, 960th Hospital of PLA, The Second Hospital of Hebei Medical University, The Second Affiliated Hospital of Dalian Medical University, Air Force Military Medical University, China
aGVHD, Stem Cell Transplant Complications
08/22
06/23
IN-DXM-EMRR, NCT06223074: Improving the Treatment of Acute Relapses in Multiple Sclerosis Through Intranasal Methylprednisolone Administration

Enrolling by invitation
2
80
RoW
IV Methylprednisolone administration, ST, Nasal Methylprednisolone (MT), Nasal MT
Universidad Nacional Autonoma de Mexico, Instituto Nacional de Neurología y Neurocirugía
Methylprednisolone, Intranasal Administration, Patients With an Active Multiple Sclerosis Relapse
11/24
02/25
2020-000855-11: USING STEROID TREATMENT TO INHIBIT INFLAMMATION AND BRAIN INJURY IN PATIENTS RESUSCITATED FROM CARDIAC ARREST. BRUG AF STEROIDBEHANDLING TIL AT MINDSKE INFLAMMATION OG HJERNESKADE I GENOPLIVEDE HJERTESTOPSPATIENTER.

Not yet recruiting
2
120
Europe
Solu-medrol, 6132, Solution for injection, Solu-Medrol
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen University Hospital Rigshospitalet
We investigate the efficacy of commercially available glucocorticoid "methylprednisolone" (Solu-Medrol) for reducing the systemic inflammatory response and neurological injury in patients resuscitated after out-of-hospital cardiac arrest. Vi undersøger den antiinflammatoriske og neuroprotektive effekt af det kommercielt tilgængelige glukokortikoid "methylprednisolon" (Solu-Medrol) i patienter genoplivet efter hjertestop uden for hospital., Patients resuscitated from out-of-hospital cardiac arrest have a high mortality due to a systemic inflammatory response and severe brain injury. We hope that Solu-Medrol can prevent this response. Patienter genoplivet efter hjertestop uden for hospital har en høj dødelighed grundet et inflammatorisk respons og svær hjerneskade. Vi håber at Solu-Medrol kan modvirke dette respons., Diseases [C] - Cardiovascular Diseases [C14]
 
 
NCT02661035: Allo HSCT Using RIC for Hematological Diseases

Completed
2
156
US
Allopurinol, Zyloprim, Fludarabine, Fludara, Cyclophosphamide, Cytoxan, ATG, Anti-thymocyte globulin, TBI, Total body irradiation, Tacrolimus, Prograf, MMF, Mycophenolate Mofetil, Peripheral Blood Stem Cells, Related or Unrelated Bone Marrow Cells
Masonic Cancer Center, University of Minnesota
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Myeloproliferative Syndromes, Hematological Diseases
04/23
05/23
NCT04305145: Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Recruiting
2
42
US
Infliximab, AVSOLA, Ixifi, Remicade, Renflexis, Methylprednisolone, Solu-Medrol, Duralone, Medralone, Medrol, M-Prednisol, Prednisone, Deltasone, Prednicot, predniSONE Intensol, Rayos, Sterapred, Sterapred DS
Massachusetts General Hospital, Dana-Farber Cancer Institute
Melanoma Stage III, Melanoma Stage IV, Skin Cancer Stage III, Skin Cancer Stage IV, Drug-Induced Colitis, Drug Toxicity, Immune-related Adverse Event
06/30
06/30
NCT04479267: Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

Recruiting
2
49
US
Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione, 53-03-2, Adasone, Cortancyl, Dacortin, , Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Prednisolone, (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, .delta.1-Hydrocortisone, 1,2-Dehydrohydrocortisone, 50-24-8, 9120, Adnisolone, Aprednislon, Capsoid, Cortalone, Cortisolone, Methylprednisolone, (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione, 6Alpha-Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Rituximab, 174722-31-7, 687451, ABP 798, BI 695500, C2B8 Monoclonal Antibody, Chimeric Anti-CD20 Antibody, CT-P10, IDEC-102, IDEC-C2B8, IDEC-C2B8 Monoclonal Antibody, MabThera, Monoclonal Antibody IDEC-C2B8, Polatuzumab Vedotin, 1313206-42-6, ADC DCDS4501A, Antibody-Drug Conjugate DCDS4501A, DCDS4501A, FCU 2711, POLATUZUMAB VEDOTIN, polatuzumab vedotin-piiq, Polivy, RG7596, Ro 5541077-000, Cyclophosphamide, 1-bis(2-chloroethyl)-amino-1-oxo-2-aza-5-oxaphosphoridin monohydrate, 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate, Doxorubicin Hydrochloride, 14-Hydroxydaunorubicin Hydrochloride, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Diffuse Large B-Cell Lymphoma, High Grade B-Cell Lymphoma w/MYC & BCL2 or BCL6 Rearrangements, High Grade B-Cell Lymphoma w/MYC, BCL2 & BCL6 Rearrangements, Double Expressor Lymphoma, High-grade B-cell Lymphoma
11/25
11/26
PULSE-MI, NCT05462730: Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial Infarction

Active, not recruiting
2
530
Europe
Methylprednisolone, Solu-Medrol, Isotonic saline, Isotonic NaCl, Placebo
Thomas Engstrom
ST Elevation Myocardial Infarction, Inflammatory Response, Myocardial Reperfusion Injury, Myocardial Injury
01/24
10/24
NCT05734625: Efficacy of Nerve Blocks for Episodic Migraine

Recruiting
2
60
US
Bupivacaine HCl 0.5% Injectable Solution, Methylprednisolone 40 MG Injection
Mayo Clinic
Episodic Migraine
02/25
07/25
NCT05350774: Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2

Enrolling by invitation
2
45
US
IV normal saline, IV immunoglobulin
National Institute of Neurological Disorders and Stroke (NINDS)
Systemic Inflammation, Neuroinflammation, Microvascular Thrombosis
12/25
12/25
NESPA, NCT06373211: Early Immunotherapy With Intravenous Immunoglobulin, Cyclophosphamide and Methylprednisolone in Patients With Anti-Hu-associated Paraneoplastic Sensory Neuronopathy

Not yet recruiting
2
21
Europe
Immunoglobulins IV (CLAYRIG), Cyclophosphamide IV, Methylprednisolone IV
Assistance Publique - Hôpitaux de Paris
Paraneoplastic Sensory Neuronopathy
06/27
06/27
NCT06412497: MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Recruiting
2
60
US
Rituximab, Rabbit ATG, Thymoglobulin, Cyclophosphamide, Fludarabine, Total Body Irradiation, TBI, Cell Infusion, Post-Transplant G-CSF, Filgrastim, Tacrolimus, Mycophenolate Mofetil, MMF
Masonic Cancer Center, University of Minnesota
Severe Aplastic Anemia, Acquired Amegakaryocytic Thrombocytopenia, Acquired Pure Red Cell Aplasia, Paroxysmal Nocturnal Hemoglobinuria
05/35
05/36
CORTICONEHI, NCT06471556: Efficacy of Methylprednisolone Pulses in Neuroendocrine Celles Hyperplasia of Infancy : An Early Phase Study

Not yet recruiting
2
18
Europe
IV Methylprednisolone pulses
Assistance Publique - Hôpitaux de Paris
Neuroendocrine Cell Hyperplasia of Infancy
11/26
04/28
NCT03292861: The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients

Enrolling by invitation
2
60
US
Thymoglobulin, Mycophenolate Mofetil, Tacrolimus, Sirolimus, Corticosteroids
Cedars-Sinai Medical Center, Genzyme, a Sanofi Company
Heart Transplantation
10/24
10/25
NCT03913559: Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

Recruiting
2
32
US
Inotuzumab ozogamicin, Besponsa, CMC-544, Methotrexate, Trexall®, Hydrocortisone, Cortisol, Cytarabine, Ara-C, Diphenhydramine, Benadryl, Acetaminophen, Tylenol, Methylprednisolone, Solu-Medrol
St. Jude Children's Research Hospital, Pfizer
Acute Lymphoblastic Leukemia
12/24
01/25
NCT05177237: Endostar Combined With Corticosteroid for Treatment of Radiation-induced Brain Necrosis in Nasopharyngeal Carcinoma

Recruiting
2
30
RoW
Endostar, Re-human endostain
Jiangxi Provincial Cancer Hospital
Nasopharyngeal Carcinoma
12/24
12/25
LIGHT, NCT06462781: Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment

Not yet recruiting
2
230
US
Lidocaine hydrochloride, lidocaine, Xylocaine-MPF, Methylprednisolone sodium succinate, methylprednisolone, SOLU-MEDROL, Standard of Care
The Cooper Health System
Refractory Migraine
03/27
03/27
I-HEP, NCT04810156: Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related Hepatitis

Recruiting
2
60
Europe
Mycophenolate Mofetil, Cellcept, Myfenax, Solu-Medrol, Methylprednisolone, Medrol, Corticosteroids, Steroid, Ursodeoxycholic acid, ursochol, Prednisone tablet, steroid
Inge Marie Svane
Hepatitis, Drug-Induced
04/25
11/25
TRIUMPH, NCT04862221: TReatment for ImmUne Mediated PathopHysiology

Recruiting
2
163
US
High-dose methylprednisolone, Solu-Medrol, Equine anti-thymocyte globulin, ATGAM, Prednisolone, 15 mg/mL oral solution National Drug Code: 62135-250-37, Placebo for prednisolone, Placebo for infusions, 0.9% Sodium chloride, Diphenhydramine, Benadryl, Methylprednisolone
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Ann & Robert H Lurie Children's Hospital of Chicago
Acute Liver Failure, Fulminant Hepatic Failure, Hepatic Encephalopathy, Acute Liver Injury, Immune Dysregulation
01/26
01/27
NCT05643638: A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD

Recruiting
2
60
US, RoW
CYP-001: Cymerus induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (MSCs), Placebo, Corticosteroids
Cynata Therapeutics Limited
Graft Versus Host Disease, Acute
04/25
12/26
NCT01624805: Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

Recruiting
2
140
US
Anti-Thymocyte Globulin, Antithymocyte Globulin, Antithymocyte Serum, ATG, ATGAM, ATS, Thymoglobulin, Cyclosporine, 27-400, Ciclosporin, CsA, Cyclosporin, Cyclosporin A, Gengraf, Neoral, OL 27-400, Sandimmun, Sandimmune, SangCya, Filgrastim, FILGRASTIM, LICENSE HOLDER UNSPECIFIED, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tevagrastim, Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Firmacort, Medlone 21, Medrate, Medrol, Medrol Veriderm, Medrone, Mega-Star, Meprolone, Methylprednisolonum, Metilbetasone Solubile, Metrocort, Metypresol, Metysolon, Predni-M-Tablinen, Prednilen, Radilem, Sieropresol, Solpredone, Summicort, Urbason, Veriderm Medrol, Wyacort, Pegfilgrastim, Filgrastim SD-01, filgrastim-SD/01, Fulphila, HSP-130, Jinyouli, Neulasta, Neulastim, Pegfilgrastim Biosimilar HSP-130, SD-01, SD-01 sustained duration G-CSF
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Aplastic Anemia, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Previously Treated Myelodysplastic Syndrome
06/26
06/26
NCT03456817: HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis

Recruiting
2
200
Canada
Treatment Arm - high dose ATG, Control Arm - standard of care
AHS Cancer Control Alberta
Graft-versus-host-disease, Relapse
09/25
09/25
R-HLH, NCT05762640: Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis

Not yet recruiting
2
20
NA
Ruxolitinib
Assistance Publique - Hôpitaux de Paris
Haemophagocytic Lymphohistiocytosis
11/26
11/27
MoTD, NCT04888741 / 2019-002419-24: Methods of T Cell Depletion Trial

Recruiting
2
400
Europe
Thymoglobulin, ATG, Cyclophosphamide, Cyclosporine, Sirolimus, Mycophenolate Mofetil, MMF
University of Birmingham, IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, Myelofibrosis
01/26
01/26
NCT04936854: Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Recruiting
2
60
Europe
Sirolimus 1 mg Oral Tablet, Rapamycin, Rapamune, Methylprednisolone, Solu-Medrol
Haukeland University Hospital
Thyroid-Associated Ophthalmopathy
01/26
05/26
POSTERITY, NCT05039619 / 2021-000097-29: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
2
40
Europe, Canada, US, RoW
Obinutuzumab, Gazyva, Placebo, Mycophenolate Mofetil, Acetaminophen/paracetamol, Diphenhydramine hydrochloride (HCl), Methylprednisolone, Prednisone
Hoffmann-La Roche, Genentech, Inc.
Lupus Nephritis
03/26
03/29
Ra-P-OCD, NCT04323566: Rituximab Treatment for Psychosis and/or Obsessive Compulsive Disorder With Probable Immune System Involvement

Enrolling by invitation
2
40
Europe
Rituximab
Uppsala University Hospital, Uppsala University
Obsessive-Compulsive Disorder, Obsessive-Compulsive Behavior, Schizophrenia, Delusional Disorder, Brief Psychotic Disorder, Schizo Affective Disorder, Other Psychoses, Unspecified Psychosis
04/26
05/26
NCT05843968: Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Nephrotic Syndrome

Recruiting
2
46
RoW
Rituximab, Rituximab Injection, Mycophenolate Mofetil, Mycophenolate Mofetil Dispersible tablets
Children's Hospital of Chongqing Medical University
Nephrotic Syndrome in Children
07/26
07/26
BRESELIBET, NCT04378647: BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant

Recruiting
2
150
Europe
Induction with Brentuximab vedotin (BV), Adcetris treatment + ESHAP as salvage therapy, Induction without Brentuximab Vedotin, ESHAP treatment as salvage therapy, Consolidation with Brentuximab Vedotin, Adcetris treatment as consolidation
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Hodgkin Lymphoma, Adult
08/26
08/26
NCT04918147: Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)

Terminated
2
8
US
elotuzumab, BMS-901608, Empliciti®, placebo for elotuzumab, normal saline, methylprednisolone, Solu-Medrol®, diphenhydramine, Benadryl®, acetaminophen, Tylenol®, famotidine, H2 blocker, prednisone, corticosteroid
National Institute of Allergy and Infectious Diseases (NIAID), Autoimmunity Centers of Excellence, Bristol-Myers Squibb, Rho Federal Systems Division, Inc.
IgG4 Related Disease, IgG4-RD
01/24
01/24
NCT00882895: Tandem Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Active, not recruiting
2
18
US
Stem cell infusion, TLI, Anti-thymocyte globulin, ATG, Atgam, Thymoglobulin, Solumedrol, Medrol, Solu-Medrol, Tacrolimus, FK-506, Prograf, Advagraf, Protopic, Mycophenolate mofetil, MMF, CellCept, Myfortic
Washington University School of Medicine
Lymphoma, Non-Hodgkin
06/28
06/28
NCT02784210: Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

Recruiting
2
30
US
Methylprednisolone, Prednisone
National Institute of Neurological Disorders and Stroke (NINDS)
Multiple Sclerosis
12/28
12/28
NCT02061800: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Active, not recruiting
1/2
14
US
CliniMACS CD34+ Reagent System, Thiotepa, Thioplex, Cyclophosphamide, Cytoxan, Alemtuzumab, Campath, Tacrolimus, Prograf, FK506, Melphalan, Alkeran, Busulfan, Busulfex, Fludarabine, Fludara, Methylprednisolone, Solu-Medrol
Diane George
Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)
07/26
07/26
NCT04066114: Treg Modulation With CD28 and IL-6 Receptor Antagonists

Completed
1/2
10
US
lulizumab pegol, BMS-931699, antithymocyte globulin (rabbit), ATG (rabbit), Thymoglobulin®, methylprednisolone, Solu-Medrol ®, tocilizumab, Actemra®, Prednisone, prednisone tablets, Rayos®, everolimus, Zortress®, belatacept, Nulojix®, mycophenolate mofetil, MMF, CellCept®, mycophenolic acid, Myfortic®
National Institute of Allergy and Infectious Diseases (NIAID), Bristol-Myers Squibb, Clinical Trials in Organ Transplantation
Living-Donor Kidney Transplant, Kidney Transplant Recipients
09/23
09/23
NCT04224558: Stem Cell Transplantation in Crohn's Disease

Recruiting
1/2
15
US
Mesna, Mesnex, Cyclophosphamide, Cytoxan, Neosar, Filgrastim, Neupogen, Granix, Apheresis catheter placement, Leukapheresis, Fludarabine, Fludara, Methylprednisolone, solu-medrol, Diphenhydramine, Benadryl, Acetaminophen, Tylenol, anti-thymocyte globulin (rabbit), thymoglobulin, lymphocyte immune globulin, ATGAM, Peripheral Blood Stem Cell Infusion
Cedars-Sinai Medical Center
Crohn Disease
01/25
01/25
NCT04151082: High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

Recruiting
1/2
35
US
Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Firmacort, Medlone 21, Medrate, Medrol, Medrol Veriderm, Medrone, Mega-Star, Meprolone, Methylprednisolonum, Metilbetasone Solubile, Metrocort, Metypresol, Metysolon, Predni-M-Tablinen, Prednilen, Radilem, Sieropresol, Solpredone, Summicort, Urbason, Veriderm Medrol, Wyacort, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Cranial Nerve Disorder, Head and Neck Carcinoma, Oropharyngeal Carcinoma
07/25
07/25
NCT05123040: Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids

Recruiting
1/2
55
US
Ruxolitinib 10 MG Oral Tablet, hCG, Pregnyl, Corticosteroids, Prednisone, IV methylprednisolone
Masonic Cancer Center, University of Minnesota
Acute-graft-versus-host Disease
09/24
09/28
NCT03952637: A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

Recruiting
1/2
45
US
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
National Human Genome Research Institute (NHGRI), Sio Gene Therapies
Lysosomal Diseases, Gangliosidosis, GM1
01/28
01/28
NCT04509219: Methylprednisolone Pulse Therapy for Coronary Artery Dilatation or Aneurysm Formation in Kawasaki Disease

Recruiting
1
10
RoW
Methylprednisolone Injection, methylprednisolone pulse therapy
Chang Gung Memorial Hospital
Mucocutaneous Lymph Node Syndrome
04/21
08/23
NCT04233164: Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus

Active, not recruiting
1
47
US
Solu-Medrol 1mg/kg, Solu-Medrol 250 mg
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Systemic Lupus Erythematous (SLE)
05/22
03/25
ChiCTR2200057375: Comparison of the efficacy of nebulized inhalation and intravenous corticosteroids in the treatment of patients with severe acute exacerbations of chronic obstructive pulmonary disease: a single-center, prospective, randomized, controlled clinical study

Not yet recruiting
1
60
 
40mg sodium methylprednisolone succinate for injection (dissolved in 0.9% saline or 5% glucose injection 50ml), intravenous infusion for 30 minutes, once a day for 5 consecutive days. ;Nebulized inhalation group: 2 mg budesonide suspension for inhalation, nebulized inhalation for 30 minutes, administered 4 times a day for 5 consecutive days.
The First Hospital of Jilin University; The First Hospital of Jilin University, The First Hospital of Jilin University
acute exacerbations of chronic obstructive pulmonary disease
 
 
NCT02780583: Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

Active, not recruiting
1
40
US
kineret, Anakinra, placebo, normal saline
University of Alabama at Birmingham
Macrophage Activation Syndrome
03/23
04/24
NCT04988256: Cyclosporine vs Steroids in DRESS

Enrolling by invitation
1
50
US
Cyclosporine, Methylprednisolone and Prednisone
University of Southern California
DRESS Syndrome, Drug-Induced Hypersensitivity Syndrome
04/25
06/25
NCT06025097: Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.

Completed
1
70
RoW
Combination Solution, PRP + Solumedrol
CMH RWP Combined Military Hospital RWP: Rawalpindi
Sensorineural Hearing Loss, Tinnitus
09/23
10/23
NCT06081101: Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint Pain

Not yet recruiting
1
20
Canada
Methylprednisolone Injection, Ketorolac Injection
McMaster University
Sacro-iliac Joint Pain
06/26
06/26
FANCA, NCT01331018: Gene Therapy for Fanconi Anemia

Terminated
1
3
US
Bone Marrow Aspiration, Filgrastim, FILGRASTIM, LICENSE HOLDER UNSPECIFIED, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tevagrastim, Genetically Engineered Hematopoietic Stem Progenitor Cells, Genetically Engineered HSPCs, Laboratory Biomarker Analysis, Leukapheresis, Leukocytopheresis, Therapeutic Leukopheresis, Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Firmacort, Medlone 21, Medrate, Medrol, Medrol Veriderm, Medrone, Mega-Star, Meprolone, Methylprednisolonum, Metilbetasone Solubile, Metrocort, Metypresol, Metysolon, Predni-M-Tablinen, Prednilen, Radilem, Sieropresol, Solpredone, Summicort, Urbason, Veriderm Medrol, Wyacort, Plerixafor, AMD 3100, JM-3100, Mozobil, SDZ SID 791, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI), Rocket Pharma Limited
Fanconi Anemia
02/24
02/24
ACTRN12622001186741: Autologous Stem Cell Transplant in Neuro-Inflammatory diseases other than multiple sclerosis

Not yet recruiting
N/A
5
 
The Alfred- Melbourne, The Alfred-Melbourne
Neuro-Inflammatory disease
 
 
ACTRN12623000321640: Chest hyperinflation and response to steroids and inhaled adrenaline in children with bronchiolitis admitted to intensive care

Not yet recruiting
N/A
211
 
Royal Children's Hospital, Royal Children's Hospital
Bronchiolitis
 
 
ChiCTR-TRC-12002662: Effect of epidural dexamethasone or methylprednisolone on post combined spinal-epidural anesthesia lumbar pain

Completed
N/A
200
 
epidural dexamethasone injection ;epidural methylprednisolone injection
Department of ICU, The third affiliated Hospital of Harbin Medical University; Level of the institution：, None
lumbar pain postoperative
 
 
ChiCTR-ONC-13003666: Long-term Effects of High-dose Intravenous Methylprednisolone Pulse Therapy on Thyroid-associated Ophthalmopathy

Completed
N/A
58
 
high-dose intravenous methylprednisolone pulse (IVMP) therapy
First Affiliated Hospital of Xi’an Jiaotong University School of Medicine; First Affiliated Hospital of Xi’an Jiaotong University School of Medicine, Self-financing
Thyroid-associated ophthalmopathy
 
 
ChiCTR-TRC-12002058: Randomized controlled clinical study of inhale budesonide and inject methylprednisolone in AECOPD patients

Completed
N/A
400
 
inhale budesonide suspension ;inject methylprednisolone sodium succinate
the 3rd affiliated hospital of Anhui Medical University (The 1st hospital of Hefei); the 3rd affiliated hospital of Anhui Medical University, self-raised funds about 60%, about 40% raised by Hefei Medical Association
chronic obstructive pulmonary disease
 
 
ChiCTR-IOR-15005906: Methylprednisolone decreases the duration of rocuronium-induced neuromuscular block

Not yet recruiting
N/A
105
 
Patients received methylprednisolone 40mg intravenously 0.5h prior to surgery ;Patients received methylprednisolone 40mg after induction of anaesthesia ;Patients received normal saline 2ml
Obstetrics and Gynecology Hospital of Fudan University; Obstetrics and Gynecology Hospital of Fudan University, no
anaesthesia
 
 
ChiCTR-BOC-16008999: The role and molecular mechanism of HDAC2 on glucocorticoid resistance formation in sudden sensorineural hearing loss

Recruiting
N/A
125
 
intratympanic methylprednisolone perfusion (0.5ml/day,40mg/ml) ;intravenous methylprednisolone 80mg/day×4day, 40mg/day×3day, 20mg/day×3day ;Not treatment
Nanjing Drum Tower Hosipital, Nanjing University Medical School; Nanjing Drum Tower Hosipital, Nanjing University Medical School, National Science Funds of China
Sudden Sensorineural Hearing Loss
 
 
ChiCTR-OOC-17013447: Diagnosis, treatment and prognosis of thyroid associated ophthalmopathy

Recruiting
N/A
50
 
high-dose intravenous methylprednisolone pulse (IVMP) therapy
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology; Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Self-financing
Thyroid-associated ophthalmopathy
 
 
ChiCTR2000029656: A randomized, open-label study to evaluate the efficacy and safety of low-dose corticosteroids in hospitalized patients with novel coronavirus pneumonia (COVID-19)

Not yet recruiting
N/A
100
 
Standard treatment ;Standard treatment and methylprednisolone for injection
Wuhan Pulmonary Hosptial; Wuhan Pulmonary Hosptial, Emergency Project for 2019-nCoV of Ministry of Science and Technology
novel coronavirus pneumonia (COVID-19)
 
 
Methyl19LGH, NCT04559113: Methylprednisolone in COVID-19 Patients

Recruiting
N/A
200
RoW
Methylprednisolone Injectable Product, solu madrol
Lahore General Hospital
SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)
12/20
12/20
ChiCTR-OOC-17013257: Efficacy evaluation of systemic glucocorticoids in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease in different phenotypes

Not yet recruiting
N/A
1044
 
intravenous use methylprednisolone 40mg qd for 5 days ;observation
West China Hospital, Sichuan University; West China Hospital, Sichuan University, National key research project of China during the 13th five-year plan period
Chronic Obstructive Pulmonary Disease
 
 
ChiCTR2000029386: Effectiveness of glucocorticoid therapy in patients with severe novel coronavirus pneumonia: a randomized controlled trial

Recruiting
N/A
48
 
Methylprednisolone, intravenous injection, 1-2mg/kg·d for 3 days. ;Without any glucocorticoid therapy
Chongqing Public Health Medical Center; Chongqing Public Health Medical Center, Chongqing Science and Technology of Bureau
Novel Coronavirus Pneumonia (COVID-19)
 
 
NCT05793359: Comparison of the Effectiveness of Two Glucocorticoid Regimens for Treatment of Graves' Orbitopathy

Completed
N/A
62
Europe
Methylprednisolone, Urbason
Medical University of Sofia
Graves Ophthalmopathy
02/21
02/21
ChiCTR2100043498: Effect of combined treatment with volatile anesthetics, dexmedetomidine, and methylprednisolone on prognosis in patients undergoing heart valve surgery

Recruiting
N/A
246
 
Intravenous methylprednisolone 120mg at anesthetic induction; Dexmedetomidine infusion at a rate of 0.4ug/kg/h after induction until the end of surgery; Volatile anesthetic to maintain anesthesia. ;Use the same technique to give the same amount or rate of normal saline at the same time point mentioned above, and use total intravenous anesthesia (propofol) throughout the surgery to maintain anesthesia
West China Hospital, Sichuan University; West China Hospital, Sichuan University, self-raised
postoperative recovery and perioperative organ protection
 
 
ChiCTR1800019155: Multi-center clinical study for vestibular conversion and rehabilitation training effect of the idiopathic sudden deafness with vertigo

Not yet recruiting
N/A
180
 
Intravenous methylprednisolone andintratympanic injection ;Intravenous methylprednisolone +intratympanic injection+intravenous of Ginaton ;shock dose hormone group
Eye & ENT Hospital of Fudan University; Eye &ENT Hospital of Fudan University, The 2018 annual science and technology innovation action plan project of Shanghai municipal science and technology commission
the idiopathic sudden deafness with vertigo
 
 
NCT04507165: Opioid-free Anesthesia in VATS Lung Resection

Not yet recruiting
N/A
100
RoW
Paravertebral block+Anterior serratus plane block, nerve block, opioid free anesthesia, OFA, opioid based anesthesia, Standard anesthesia
Peking University People's Hospital
Opioid Free Anesthesia
07/21
07/22
SUCCES, NCT03942861: Sonographic Assessment in Severe Ulcerative Colitis Patients Admitted for Intravenous Corticosteroids and Eligible for Infliximab Rescue Therapy; a Prospective Clinician-blinded Observational Study Protocol.

Recruiting
N/A
50
Europe
Solu-Medrol
Copenhagen University Hospital at Herlev
Ulcerative Colitis, Ultrasound Therapy; Complications
09/21
02/22
NCT06189586: Comparison of Aerosol Inhalation and Intravenous Glucocorticoid in the Treatment of Severe AECOPD

Enrolling by invitation
N/A
100
RoW
aerosol inhalation of glucocorticoids, intravenous injection of glucocorticoids
Dong Yang, Jilin University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
12/24
07/25
NCT04810819: Clinical Study of the Effect of Methylprednisolone Combined

Not yet recruiting
N/A
110
NA
Methylprednisolone 40 MG Injection;Dihydroxypropyltheophylline;, Placebo
Qianfoshan Hospital
Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics
10/21
12/21
NCT05990894: Steroid for Treatment of Acute/Subacute Severe Cerebral Venous Thrombosis.

Completed
N/A
248
RoW
Methylprednisolone
Xuanwu Hospital, Beijing
Cerebral Venous Thrombosis
12/21
12/21
NCT03586557: Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic Neuritis

Recruiting
N/A
142
RoW
Corticosteroid & Plasma exchange, CS+PE, Corticosteroid, CS
Chinese PLA General Hospital
Optic Neuritis
12/21
12/21
ChiCTR1800020060: A prospective, randomized, multicenter, controlled trial for the use of glucocorticoids in the treatment of AECOPD through different routes and courses

Not yet recruiting
N/A
480
 
6ml (3mg) Budesonide aerosol inhalation for Bid*5 days ;6ml (3mg) Budesonide aerosol inhalation for Bid*9-14 days ;Methylprednisolone 40 mg intravenous drip or oral prednisolone 40 mg, Qd*5 days ;Methylprednisolone 40 mg intravenous drip or oral prednisolone 40 mg, Qd*9-14 days
Hefei First People's Hospital; Hefei First People's Hospital, Anhui Key Research and Development Plan
Chronic obstructive pulmonary disease
 
 
ChiCTR1900025244: The efficacy and safety of immunomodulatory treatment in HBV-related ACLF

Not yet recruiting
N/A
135
 
common medical treatment, combined with methylprednisolone 40mg intravenously once a day, discontinued after 5 days ;common medical treatment, combined with the Zidaxian 1.6mg subcutaneous injection once a day, discontinued after 5 days. ;Routine medical treatment.
Zhejiang University; The Third Affiliated Hospital, SUN YAT-SEN University, Ministry of Finance，China
HBV-ACLF
 
 
NCT04808856: Treatment of Refractory Gout With ACTH or Methylprednisolone

Recruiting
N/A
60
RoW
Adrenocorticotropic Hormone, Methylprednisolone Injection
Shanghai 10th People's Hospital
Gout
04/22
04/22
NCT03122847: Glucocorticoids and Bone in Graves' Ophthalmopathy

Active, not recruiting
N/A
30
Europe
Methylprednisolone
Torben Harsløf, Odense University Hospital
Graves Ophthalmopathy
07/22
07/23
ChiCTR1900027528: Prospective observational cohort study on the efficacy of different treatment methods for severe neuroimmune diseases

Not yet recruiting
N/A
390
 
plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;Intravenous immunoglobulin
Department of Neurology, Xiangya Hospital, Central South University; Xiangya Hospital, Central South University, Self-raised
Severe Neuroimmune Disease
 
 
ChiCTR2000038871: Clinical study of batroxobin injection in the treatment of sudden deafness

Recruiting
N/A
210
 
Batroxobin + methylprednisolone intravenous injection ;Methylprednisolone intravenous injection + dexamethasone injection ;Batroxobin + methylprednisolone intravenous injection + dexamethasone tympanic injection
The First Affiliated Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangzhou Medical University, Tinnitus stimulation non-invasive neuromodulation therapy
Sudden deafness
 
 
NCT05455398: Establishment of a Trans-round Window Inner Ear Continuous Drug Delivery System for the Treatment of Severe-to-profound Sudden Sensorineural Hearing Loss

Recruiting
N/A
218
RoW
Surgical treatment of round window niche enlargement via round window for inner ear drug delivery, Drum chamber drug injection
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hearing Loss, Sudden
11/23
03/24
ICOMI, NCT03915223: Soft Part Management for Surgical Fractures of the Lower Limb

Completed
N/A
104
Europe
leg fracture
University Hospital, Clermont-Ferrand
Leg Injuries, Fracture, Edema
12/23
05/24
REVIVES, NCT06203847: The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA

Not yet recruiting
N/A
1200
RoW
Combination group, Standard group
National Taiwan University Hospital
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Emergency Medical Services
06/26
12/26
NCT05842681: Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Not yet recruiting
N/A
30
RoW
Azithromycin, azithromycin 500 mg oral tablet, Methylprednisolone, methylprednisolone 500 mg
Assiut University
Idiopathic Pulmonary Fibrosis
03/24
06/24
ChiCTR2100047811: The relationship between FeNO50 +CANO combined detection and treatment response in patients with acute exacerbation of COPD

Not yet recruiting
N/A
103
 
Intravenous methylprednisolone (40mg/ day) was used for 1-3 days during hospitalization; Intravenous methylprednisolone (40mg/ day) was used for 4-7 days during hospitalization ;No systemic hormones were used during hospitalization
Shenzhen Second People's Hospital; Shenzhen Second People's Hospital, Funding from hospital-level clinical research projects in 2021
chronic obstructive pulmonary disease
 
 
NCT06068829: Inebilizumab and Rituximab in Neuromyelitis Optica Spectrum Disorders

Not yet recruiting
N/A
80
NA
Inebilizumab, Rituximab(RTX)
Feng Jinzhou
Neuromyelitis Optica Spectrum Disorders
06/24
06/25
NCT05964725: The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus

Recruiting
N/A
86
RoW
Receive traditional medical therapy and transcranial direct current stimulation, Receive traditional medical therapy and sham stimulation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method, Female, Male, Human, Treatment Outcome
08/24
08/24
NCT06118398: Efgartigimod in Acute Neuromyelitis Optica Spectrum Disorders

Not yet recruiting
N/A
24
NA
Intravenous methylprednisolone (IVMP) and Efgartigimod, IVMP
Feng Jinzhou
Neuromyelitis Optica, Efgartigimod
11/24
05/25
ChiCTR2300071734: Effectiveness and safety evaluation of Chinese medicine in the treatment of patients with PPF with phlegm heat-blood stasis obstructing in the lung: a randomized controlled, open-label clinical trial

Not yet recruiting
N/A
50
 
Mahuang, Kuxingren, Gancao, Fengfang, Dilong, Chishao, Jiezi, Laifuzi, Zisuzi, Huangqi, Huangqin, Qinghao ;1. All patients will take pulmonary rehabilitation therapy; 2. Patients with hypoxia at rest, will take long-term oxygen therapy; 3. Patients with pulmonary infection will take empirical anti-infective treatment, and targeted anti-infective treatment will be given after obtaining the results of drug sensitivity test. For the dosage of hormones and immunomodulators, our recommendations are summarised below: (1) Glucocorticoid: the initial dose of glucocorticoid can range from oral prednisone (1mg·kg-1·d-1) to intravenous methylprednisolone (500-1000 mg/d) for 3 days, then reduced to prednisone or equivalent dose, gradually reduced to maintenance dose in 4-8 weeks according to the patient's condition and treatment response, and maintained close follow-up; (2) Cyclophosphamide: adhere to the daily use of 2mg, the initial dose is prescribed daily oral 25mg-50mg, and increase 25mg every other week to two weeks, according to this cycle until the maximum dose reaches the daily 150mg; (3) Azathioprine: administered at 2-3 mg·kg-1·d-1. The initial dose is 25-30mg/d, and then 25mg will be increased every 7 to 14 days until the maximum amount of 150mg/d is reached; In addition, if the subjects had taken oral corticosteroids for more than one month before entering the trial, and the hormone had reached the maintenance dose, or if they had taken oral immunomodulators for more than one month before entering the trial, the original drug treatment regimen should not be changed during the clinical observation, the investigators should record it completely and truthfully.
Hospital of Chengdu University of Traditional Chinese Medicine; Beijing University of Chinese Medicine, National Natural Science Foundation of China (No.81973713)
progressive pulmonary fibrosis（PPF）
 
 
NCT01630850: Islet Transplantation in Patients With "Brittle" Type I Diabetes

Recruiting
N/A
20
US
Allogenic islet cells (human, U. Chicago), Intraportal infusion of islet cells
University of Chicago
Diabetes Mellitus, Type 1
05/25
06/30
ChiCTR2000034214: A multicenter, prospective, cohort study for the efficacy and adverse reactions of ANCA associated glomerulonephritis based on ARRS score

Not yet recruiting
N/A
106
 
Induction remission stage: Glucocorticoid + cyclophosphamide; Maintain remission stage: Hormone + azathioprine / methotrexate / mycophenolate mofetil ;Induction remission stage: Methylprednisolone + intravenous cyclophosphamide or rituximab; Maintain remission stage: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + cyclophosphamide + rituximab + plasma exchange; Maintain: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + intravenous cyclophosphamide; Maintain: Hormone + azathioprine / methotrexate / mycophenolate mofetil
Children's Hospital Affiliated to Chongqing Medical University; Children's Hospital Affiliated to Chongqing Medical University, self-financing
ANCA associated glomerulonephritis
 
 
ChiCTR2200058688: A prospective, single-center, randomized controlled trial of glucocorticoid impulse therapy for acute exacerbation of idiopathic pulmonary fibrosis

Not yet recruiting
N/A
60
 
Methylprednisolone 500mg/qd intravenous for 3 days ;Methylprednisolone 160mg/qd intravenous for 3 days，then taped gradually.
Nanjing Drum Tower Hospital, The Affiliated Nanjing University Medical School; Nanjing Drum Tower Hospital, The Affiliated Nanjing University Medical School, Self-finance
Acute exacerbation of idiopathic pulmonary fibrosis
 
 
NCT05891379: Inebilizumab in Acute Neuromyelitis Optica Spectrum Disorders

Not yet recruiting
N/A
50
NA
Inebilizumab, oral immunosuppressant
Xuanwu Hospital, Beijing, Jiangsu Hansoh Pharmaceutical Co., Ltd.
Neuromyelitis Optica Spectrum Disorder
07/25
07/25
 

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