Leukemia  >>  methylprednisolone sodium succinate  >>  Phase 2
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19 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
NCT01177371: High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Completed
2
13
US
busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, Myelosan, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, Enduxan, allogeneic bone marrow transplantation, bone marrow therapy, allogeneic, bone marrow therapy, allogenic, transplantation, allogeneic bone marrow, transplantation, allogenic bone marrow, methylprednisolone, A-MethaPred, Depo-Medrol, Medrol, MePRDL, Solu-Medrol, Wyacort, methotrexate, Abitrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, cyclosporine, 27-400, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune
Case Comprehensive Cancer Center
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With T(15;17)(q22;q12), Adult Acute Myeloid Leukemia With T(16;16)(p13;q22), Adult Acute Myeloid Leukemia With T(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Acute Promyelocytic Leukemia (M3), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myeloid Leukemia in Remission, Childhood Acute Myelomonocytic Leukemia (M4), Childhood Acute Promyelocytic Leukemia (M3), Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, De Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-Cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Testicular Lymphoma, Waldenstrom Macroglobulinemia
02/00
02/10
NCT00109993: Campath-1H + FK506 and Methylprednisolone for GVHD

Completed
2
34
US
alemtuzumab, methylprednisolone, tacrolimus
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Neuroblastoma, Ovarian Cancer, Testicular Germ Cell Tumor
06/06
05/07
NCT00003335: Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Completed
2
44
US
anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
11/07
01/12
NCT00354172: Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.

Terminated
2
16
US
aldesleukin, IL-2, interleukin-2, filgrastim, granulocyte colony-stimulating factor (G-CSF), natural killer cell (NK) therapy, NK cells, cyclophosphamide, Cytoxan, cyclosporine, cyclosporin, fludarabine phosphate, Fludara, methylprednisolone, Medrol, Solu-Medrol, Depo-Medrol, methylprednisolone sodium succinate, mycophenolate mofetil, mycophenolic acid, Umbilical Cord Blood Transplantation (UCBT), allogeneic transplant, Total body irradiation (TBI), radiation
Masonic Cancer Center, University of Minnesota
Leukemia, Myelodysplastic Syndromes
08/08
08/08
NCT00186628: Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD

Completed
2
36
US
Total lymphoid irradiation, TLI, Rituximab, Rituxan, Anti-thymoglobulin, rabbit (ATG, rabbit ATG), Cyclosporine, CSP, Sandimmune, Mycophenylate mofetil, MMF, CellCept, Filgrastim, G-CSF, Granulocyte-colony stimulating factor, Neupogen, Granisetron, Sancuso, Solumedrol, Medrol, Depo-Medrol, A-Methapred, Acetaminophen, Tylenol, Diphenhydramine, Benadryl, Hydrocortisone, Westcort
Stanford University, The Leukemia and Lymphoma Society, National Cancer Institute (NCI)
Leukemia, Mast-Cell, Mantle-cell Lymphoma
11/10
12/10
NCT00185692: Allogeneic Transplantation From Related Haploidentical Donors

Completed
2
16
US
non-myeloablative hematopoietic cell transplantation, Peripheral-blood stem-cell transplantation, Anti-Thymocyte Globulin, ATG, Cyclosporine, INN/BAN, USAN, CSA, Mycophenolate Mofetil, MMF, CellCept, G-CSF, Granulocyte colony-stimulating factor, CSF 3, Solumedrol, 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate, Acetaminophen, Tylenol, Diphenydramine, Benadryl, Allermax, Q-Dryl, Diphen Cough, Hydrocortisone, Hydrocortisone Sodium Phosphate
Stanford University
Blood Cancer, Leukemia, Graft Versus Host Disease, Malignancy, CLL, NHL, Hodgkin's Disease, MDS
12/10
12/10
NCT00084695: Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases

Unknown status
2
25
US
anti-thymocyte globulin, busulfan, cyclophosphamide, fludarabine phosphate, melphalan, methylprednisolone, radiation therapy
Milton S. Hershey Medical Center
Childhood Langerhans Cell Histiocytosis, Fanconi Anemia, Leukemia, Lymphoma, Myelodysplastic Syndromes, Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
12/12
 
ENZON-OHSU-4913, NCT01005914: Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Terminated
2
11
US
cyclophosphamide, Cytoxan, Neosar, CTX, cytarabine, Cytosar-U, Ara-C, Arabinosylcytosine, dexamethasone, Decadron, DexPak, dex, doxorubicin hydrochloride, Adriamycin RDF, Adriamycin PFS, imatinib mesylate, Gleevec, Glivec, methotrexate, Trexall, Rheumatrex, MTX, methylprednisolone, Medrol, Depo-Medrol, Solu-Medrol, pegaspargase, Onscapar, PEG-L-asparaginase, vincristine sulfate, Marqibo
OHSU Knight Cancer Institute
Leukemia
03/13
05/14
NCT00671658: Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia

Completed
2
220
US
Rituximab, Rituxan, Cyclophosphamide (CTX), Cytoxan, Neosar, Doxorubicin, Adriamycin, Rubex, Vincristine, Oncovin, Vincasar Pfs, Dexamethasone, Decadron, Methotrexate (MTX), Rheumatrex, Cytarabine, Ara-C, Cytosar-U, Arabinosylcytosine, DepoCyt, G-CSF, Filgrastim, Neupogen, Mesna, Mesnex, Pegylated asparaginase, Pegaspargase, Oncaspar, Polyethylene Glycol Conjucated Lasparaginase-H, Pegfilgrastim, Neulasta, PEG-G-CSF, Solumedrol, Methylprednisolone, Depo-Medrol, Medrol
M.D. Anderson Cancer Center
Leukemia, Acute Lymphoblastic Leukemia
07/13
07/13
NCT01093586: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Completed
2
14
US
double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration, fluorescence in situ hybridization, fluorescence in situ hybridization (FISH), busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, Myelosan, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, Enduxan, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, methylprednisolone, A-MethaPred, Depo-Medrol, Medrol, MePRDL, Solu-Medrol, Wyacort, cyclosporine, 27-400, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune, mycophenolate mofetil, Cellcept, MMF, flow cytometry, allogeneic hematopoietic stem cell transplantation
Case Comprehensive Cancer Center
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Minimally Differentiated Myeloid Leukemia (M0), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Prolymphocytic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Splenic Marginal Zone Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia, T-cell Large Granular Lymphocyte Leukemia, Waldenstrom Macroglobulinemia
12/15
12/15
BOMP, NCT01612988: Treatment With Bendamustine, Ofatumumab and MethylPrednisolone in Relapsed B-CLL

Checkmark EHA 2014
May 2014 - May 2014: EHA 2014
Checkmark ASH 2013
Nov 2013 - Nov 2013: ASH 2013
Checkmark ASH 2013
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Terminated
2
74
Europe
BOMP
French Innovative Leukemia Organisation
B-cell Chronic Lymphocytic Leukemia (B-CLL)
12/15
04/18
NCT00553202: Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Completed
2
158
Canada, US
anti-thymocyte globulin, Rabbit ATG, RATG-Rabbit, Antithymocyte Globulin, Thymoglobulin, NSC #720095, busulfan, Busulfex, NSC #750, cyclophosphamide, Cytoxan, NSC #26271, cyclosporine, CYA, Sandimmune, Neoral, Gengraf, NSC #290193, methotrexate, MTX, amethopterin, NSC #000740, methylprednisolone, Solu-Medrol, A-Methapred, Medrol, NSC #19987, tacrolimus, FK-506, Prograf, NSC #717865, laboratory biomarker analysis, pharmacological study, allogeneic bone marrow transplantation, bone marrow therapy, allogeneic, allogenic, transplantation, allogeneic bone marrow, allogenic bone marrow, allogeneic hematopoietic stem cell transplantation
Children's Oncology Group, National Cancer Institute (NCI)
Leukemia
06/16
03/20
NCT02500550 / 2015-002821-20: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Checkmark AIR-008 study for GVHD
Jan 2018 - Jan 2018: AIR-008 study for GVHD
Checkmark Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Dec 2016 - Dec 2016: Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Completed
2
15
Europe, Canada, RoW
ATIR101, Haploidentical hematopoietic stem cell transplantation (HSCT), TBI regime, Non-TBI regime
Kiadis Pharma
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome
07/18
12/18
NCT01319981: Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

Completed
2
31
US
Rituximab, Rituxan, Imatinib, Imatinib Mesylate, Gleevec, ST1571, NSC-716051, Cyclophosphamide, Cytoxan, Neosar, Doxorubicin, Adriamycin, Rubex, Mesna, Mesnex, VSLI, Liposomal Vincristine, Vincristine Sulfate Liposomes Injection, Marqibo, Solu-Medrol, Methylprednisolone, Depo-Medrol, Medrol, Methotrexate, Ara-C, Cytarabine, Cytosar, DepoCyt, Cytosine Arabinosine Hydrochloride, G-CSF, Filgrastim, Neupogen, Pegfilgrastim, Neulasta, Dexamethasone, Decadron
M.D. Anderson Cancer Center, Spectrum Pharmaceuticals, Inc
Leukemia
11/20
11/20
NCT02661035: Allo HSCT Using RIC for Hematological Diseases

Completed
2
156
US
Allopurinol, Zyloprim, Fludarabine, Fludara, Cyclophosphamide, Cytoxan, ATG, Anti-thymocyte globulin, TBI, Total body irradiation, Tacrolimus, Prograf, MMF, Mycophenolate Mofetil, Peripheral Blood Stem Cells, Related or Unrelated Bone Marrow Cells
Masonic Cancer Center, University of Minnesota
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Myeloproliferative Syndromes, Hematological Diseases
04/23
05/23
NCT03913559: Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

Recruiting
2
32
US
Inotuzumab ozogamicin, Besponsa, CMC-544, Methotrexate, Trexall®, Hydrocortisone, Cortisol, Cytarabine, Ara-C, Diphenhydramine, Benadryl, Acetaminophen, Tylenol, Methylprednisolone, Solu-Medrol
St. Jude Children's Research Hospital, Pfizer
Acute Lymphoblastic Leukemia
12/24
01/25
MoTD, NCT04888741 / 2019-002419-24: Methods of T Cell Depletion Trial

Recruiting
2
400
Europe
Thymoglobulin, ATG, Cyclophosphamide, Cyclosporine, Sirolimus, Mycophenolate Mofetil, MMF
University of Birmingham, IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, Myelofibrosis
01/26
01/26
NCT02464657: Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Completed
1/2
44
US
Nivolumab, BMS-936558, Opdivo, Idarubicin, Idamycin, Cytarabine, Ara-C, Cytosar, DepoCyt, Cytosine Arabinosine Hydrochloride, Solu-medrol, Methylprednisolone, Depo-Medrol, Medrol, Dexamethasone, Decadron
M.D. Anderson Cancer Center, Bristol-Myers Squibb
Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome
05/20
05/20
NCT02061800: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Active, not recruiting
1/2
14
US
CliniMACS CD34+ Reagent System, Thiotepa, Thioplex, Cyclophosphamide, Cytoxan, Alemtuzumab, Campath, Tacrolimus, Prograf, FK506, Melphalan, Alkeran, Busulfan, Busulfex, Fludarabine, Fludara, Methylprednisolone, Solu-Medrol
Diane George
Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)
07/26
07/26

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