CNS Disorders  >>  methylprednisolone sodium succinate  >>  Phase 2
Welcome,         Profile    Billing    Logout  

24 Trials

Remove FilterRemove Filter

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
ACTRN12622000530729: Autologous Stem Cell Transplant in other Neuro-Inflammatory diseases

Not yet recruiting
2
20
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Neuromyelitis Optica, Stiff Person Syndrome, Myasthenia Gravis, Central Nervous System Vasculitis
 
 
ACTRN12619000348156: Autologous Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis.

Recruiting
2
50
 
Alfred Health, Alfred Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12609000602224: Erythropoietin plus methylprednisolone versus methylprednisolone plus placebo in the treatment of acute spinal cord injury: A pilot study

Completed
2
30
 
Shiraz University of Medical Sciences, Pooyesh Darou
Acute spinal cord injury
 
 
ACTRN12616000151437: A Phase II study: Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis .

Recruiting
2
20
 
Austin Health, Austin Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12622000536763: Autologous Stem Cell Transplant in Multiple Sclerosis

Recruiting
2
30
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Multiple Sclerosis
 
 
2010-023560-40: Blood stem cell transplantation for patients with relapsiong-remitting multiple sclerosis, in whom standard treatment has failed. Blodstamcellstransplantation för patienter med skovvis förlöpande MS (multipel sklerosis), där standardbehandling givit otillräcklig effekt.

Ongoing
2
120
Europe
, Powder for solution for injection, Powder for infusion*, Solution for injection, Powder and solvent for dispersion for injection, Tysabri, Sendoxan, Thymoglobuline, Neupogen, Solu-Medrol
Uppsala l�ns landsting
Relapsing-remitting multiple sclerosis
 
 
NCT01039103 / 2009-013884-21: Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS)

Terminated
2
15
Europe
PEG-liposomal prednisolone sodium phosphate, Nanocort, Methylprednisolone, Solu-Medrol
Galapagos NV
Acute Exacerbation of Remitting Relapsing Multiple Sclerosis, Clinically Isolated Syndrome
11/11
11/11
RESTORE, NCT01071083 / 2009-017490-38: Treatment Interruption of Natalizumab

Checkmark Interim Data AAN (MS)
Mar 2012 - Mar 2012: Interim Data AAN (MS)
Completed
2
175
US, Europe
natalizumab, interferon beta 1-a, methylprednisolone, IV placebo, glatiramer acetate
Biogen, Elan Pharmaceuticals
Relapsing Remitting Multiple Sclerosis
11/11
11/11
NCT01884571: Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)

Completed
2
31
US
Basiliximab, Simulect, Methylprednisolone, Solumedrol, Prednisone, Deltasone, Orasone, Tacrolimus, Prograf, Mycophenolate mofetil, Cellcept
Emory University, ALS Association
Amyotrophic Lateral Sclerosis (ALS)
01/16
01/16
2018-000620-34: Imatinib treatment for Multiple Sclerosis (MS) Relapses

Ongoing
2
200
Europe
Solu-Medrol, Film-coated tablet, Injection, Solu-Medrol
Department of Clinical Neuroscience, Karolinska Institutet, Vetenskapsrådet
Patients with clinically definite Multiple Sclerosis (MS) according to the McDonald Criteria, or possible MS (also named clinically isolated syndrome-CIS, as a first manifestation of MS, where there are radiological and/or cerebrospinal fluid signs consistent with MS), which display an acute relapse, Patients with Multiple Sclerosis (MS) with a relapse or with symptoms and signs giving rise to high suspicion of MS with relapse, Diseases [C] - Nervous System Diseases [C10]
 
 
INCREASE, NCT03387046: A Pilot Study in Participants With Relapsing Remitting Multiple Sclerosis (RR-MS)

Terminated
2
7
Europe
D-aspartate, Placebo, IFN beta-1a, Methylprednisolone
Merck KGaA, Darmstadt, Germany
Multiple Sclerosis, Relapsing-Remitting
01/19
01/19
EFFRITE, NCT02545959: Intrathecal Rituximab in Progressive Multiple Sclerosis

Completed
2
10
Europe
Rituximab IT, intrathecal rituximab (Mabthera), methylprednisolone IV, Solumedrol, Rituximab IV, Mabthera
Centre Hospitalier de PAU, University Hospital, Bordeaux
Multiple Sclerosis, Chronic Progressive, Nervous System Diseases
02/19
09/19
STEROHCA, NCT04624776: Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest

Completed
2
158
Europe
Methylprednisolone, Solu-Medrol, Isotonic saline, Placebo
Christian Hassager
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome, Systemic Inflammatory Response Syndrome, Neurological Injury
07/22
02/23
NCT03674099: Imatinib for Multiple Sclerosis (MS) Relapses

Recruiting
2
200
Europe
Imatinib Mesylate, Methylprednisolone
Tomas Olsson, The Swedish Research Council
Multiple Sclerosis
12/22
07/23
IN-DXM-EMRR, NCT06223074: Improving the Treatment of Acute Relapses in Multiple Sclerosis Through Intranasal Methylprednisolone Administration

Enrolling by invitation
2
80
RoW
IV Methylprednisolone administration, ST, Nasal Methylprednisolone (MT), Nasal MT
Universidad Nacional Autonoma de Mexico, Instituto Nacional de Neurología y Neurocirugía
Methylprednisolone, Intranasal Administration, Patients With an Active Multiple Sclerosis Relapse
11/24
02/25
2020-000855-11: USING STEROID TREATMENT TO INHIBIT INFLAMMATION AND BRAIN INJURY IN PATIENTS RESUSCITATED FROM CARDIAC ARREST. BRUG AF STEROIDBEHANDLING TIL AT MINDSKE INFLAMMATION OG HJERNESKADE I GENOPLIVEDE HJERTESTOPSPATIENTER.

Not yet recruiting
2
120
Europe
Solu-medrol, 6132, Solution for injection, Solu-Medrol
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen University Hospital Rigshospitalet
We investigate the efficacy of commercially available glucocorticoid "methylprednisolone" (Solu-Medrol) for reducing the systemic inflammatory response and neurological injury in patients resuscitated after out-of-hospital cardiac arrest. Vi undersøger den antiinflammatoriske og neuroprotektive effekt af det kommercielt tilgængelige glukokortikoid "methylprednisolon" (Solu-Medrol) i patienter genoplivet efter hjertestop uden for hospital., Patients resuscitated from out-of-hospital cardiac arrest have a high mortality due to a systemic inflammatory response and severe brain injury. We hope that Solu-Medrol can prevent this response. Patienter genoplivet efter hjertestop uden for hospital har en høj dødelighed grundet et inflammatorisk respons og svær hjerneskade. Vi håber at Solu-Medrol kan modvirke dette respons., Diseases [C] - Cardiovascular Diseases [C14]
 
 
NCT05734625: Efficacy of Nerve Blocks for Episodic Migraine

Recruiting
2
60
US
Bupivacaine HCl 0.5% Injectable Solution, Methylprednisolone 40 MG Injection
Mayo Clinic
Episodic Migraine
02/25
07/25
LIGHT, NCT06462781: Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment

Not yet recruiting
2
230
US
Lidocaine hydrochloride, lidocaine, Xylocaine-MPF, Methylprednisolone sodium succinate, methylprednisolone, SOLU-MEDROL, Standard of Care
The Cooper Health System
Refractory Migraine
03/27
03/27
TRIUMPH, NCT04862221: TReatment for ImmUne Mediated PathopHysiology

Recruiting
2
163
US
High-dose methylprednisolone, Solu-Medrol, Equine anti-thymocyte globulin, ATGAM, Prednisolone, 15 mg/mL oral solution National Drug Code: 62135-250-37, Placebo for prednisolone, Placebo for infusions, 0.9% Sodium chloride, Diphenhydramine, Benadryl, Methylprednisolone
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Ann & Robert H Lurie Children's Hospital of Chicago
Acute Liver Failure, Fulminant Hepatic Failure, Hepatic Encephalopathy, Acute Liver Injury, Immune Dysregulation
01/26
01/27
Ra-P-OCD, NCT04323566: Rituximab Treatment for Psychosis and/or Obsessive Compulsive Disorder With Probable Immune System Involvement

Enrolling by invitation
2
40
Europe
Rituximab
Uppsala University Hospital, Uppsala University
Obsessive-Compulsive Disorder, Obsessive-Compulsive Behavior, Schizophrenia, Delusional Disorder, Brief Psychotic Disorder, Schizo Affective Disorder, Other Psychoses, Unspecified Psychosis
04/26
05/26
NCT02784210: Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

Recruiting
2
30
US
Methylprednisolone, Prednisone
National Institute of Neurological Disorders and Stroke (NINDS)
Multiple Sclerosis
12/28
12/28
NCT01046786: Safety and Feasibility of Umbilical Cord Blood Cell Transplant Into Injured Spinal Cord

Completed
1/2
8
RoW
Umbilical Cord Blood Mononuclear Cell, Methylprednisolone, Lithium
China Spinal Cord Injury Network, Chinese University of Hong Kong, The University of Hong Kong
Spinal Cord Injuries
10/13
12/13
NCT02282514: Stem Cell Transplantation for Stiff Person Syndrome (SPS)

Terminated
1/2
23
US
Autologous Hematopoietic Stem Cells, Cyclophosphamide, Cytoxan, Neosar, Endoxan, Mesna, Mesnex, rATG, Thymoglobulin, Methylprednisolone, Solu-Medrol, G-CSF, Neupogen, Filgrastim, Granix, Zarxio, Rituxan, Rituximab
Northwestern University
Stiff-Person Syndrome
08/19
08/19
NCT03752307: Safety and Tolerability of ISX (Isoxsuprine HCL) in MS Relapses

Completed
1/2
2
US
Isoxsuprine Hydrochloride, Duvadilan, Placebo, Corticosteroid, Methylprednisolone, Prednisone
University of New Mexico
Multiple Sclerosis
07/23
07/23

Download Options