Autoimmune Diseases  >>  methylprednisolone sodium succinate  >>  Phase 3
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
NCT01392833: Steroids and Azathioprine in Advanced IgAN

Completed
3
46
Europe
methylprednisolone, solumedrol, azathioprine, azatioprina, prednisone, deltacortene
A. Manzoni Hospital
IgA Nephropathy, Chronic Kidney Disease
11/06
01/08
SERENE, NCT00299130 / 2005-002392-32: A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis

Completed
3
511
NA
Folate, Methotrexate, Methylprednisolone, Placebo, Rituximab, MabThera®, Rituxan®
Genentech, Inc., Hoffmann-La Roche
Rheumatoid Arthritis
06/08
07/13
VOYAGER, NCT00381810: A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus

Terminated
3
31
US
Rituximab, Methylprednisolone, Acetaminophen, Diphenhydramine
Genentech, Inc.
Lupus Erythematosus, Systemic
07/08
02/12
SCORE, NCT00578305 / 2007-001585-33: A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate

Completed
3
185
Canada, Europe, RoW
Rituximab, MabThera®, Rituxan®, Placebo, Methylprednisolone, Methotrexate, Folic acid or folate
Hoffmann-La Roche
Rheumatoid Arthritis
11/09
05/13
PROMESS, NCT00241254: Efficacy of Cyclophosphamide Versus Methylprednisolone in Patients With Secondary Progressive Multiple Sclerosis

Completed
3
138
Europe
Cyclophosphamide (drug), Methylprednisolone (drug)
University Hospital, Bordeaux, Ministry of Health, France
Multiple Sclerosis, Chronic Progressive
03/10
03/12
SUNDIAL, NCT00443651: A Study of the Safety of Rituximab in Combination With Other Anti-Rheumatic Drugs in Subjects With Active Rheumatoid Arthritis

Completed
3
578
NA
Rituximab, Anti-inflammatory drugs
Genentech, Inc., Biogen
Rheumatoid Arthritis
05/11
02/13
NCT01870128: Comparison of Three Different Treatment Regimes in Early Rheumatoid Arthritis: A Randomized Open-labelled Trial

Completed
3
60
RoW
Combination Steroid, Methylprednisolone 1000 mg intravenous for 3 days, Methotrexate, Methotrexate 15 to 25 mg PO per week, Combination, Hydroxychloroquine 200 mg Twice daily, Sulfasalazine 2000 to 3000 mg per day
All India Institute of Medical Sciences, New Delhi
Rheumatoid Arthritis
06/11
06/11
NCT00376077: A Randomized Study of IVIG vs. IVIG With High Dose Methylprednisolone in Childhood ITP.

Completed
3
32
Canada
Methylprednisolone and IVIG, Solumedrol, Placebo and IVIG
The Hospital for Sick Children, Bayer
Immune Thrombocytopenic Purpura
03/16
04/16
STRIVE, NCT02398994 / 2014-002335-34: A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis

Terminated
3
2
Europe
Intravenous Methylprednisolone, Intravenous Immunoglobulin
Guy's and St Thomas' NHS Foundation Trust, King's College London, Barts and the London School of Medicine and Dentistry, Cardiff University, University College, London, King's College Hospital NHS Trust, Great Ormond Street Hospital for Children NHS Foundation Trust, Barts & The London NHS Trust, Alder Hey Children's NHS Foundation Trust, Walton Centre NHS Foundation Trust, Oxford University Hospitals NHS Trust, Birmingham Women's and Children's NHS Foundation Trust, University Hospital Birmingham NHS Foundation Trust, Cardiff and Vale University Health Board, North Bristol NHS Trust, University Hospitals Bristol and Weston NHS Foundation Trust, Manchester University NHS Foundation Trust, Northern Care Alliance NHS Foundation Trust, University Hospital Southampton NHS Foundation Trust, Newcastle-upon-Tyne Hospitals NHS Trust, Nottingham University Hospitals NHS Trust, NHS Lothian
Myelitis, Transverse, Neuromyelitis Optica
03/16
03/16
NCT00947895: Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone

Terminated
2/3
30
US
Methylprednisolone, Solumedrol, ACTH, H.P. Acthar Gel, Repository corticotropin injection, Adrenocorticotropin hormone, IV placebo, IM placebo
Neurologique Foundation, Inc., Mallinckrodt
Multiple Sclerosis
01/11
01/11
NCT00595335: Trial of Rituximab for Graves' Ophthalmopathy

Completed
2/3
25
US
Rituximab, Rituxan, MabThera, Saline, Methylprednisolone, Medrol, Solu-Medrol
Rebecca Bahn, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Center for Research Resources (NCRR)
Thyroid-associated Ophthalmopathy
03/13
09/13

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