| Xeomin (incobotulinumtoxinA) / Merz Pharma |
2018-001597-16`ACTRN12609000922279: Efficacy of botulinum toxin in treating temporomandibular disorders Kliininen tutkimus botuliinihoidon tehokkuudesta potilailla joilla on diagnosoitu purentaelimistön toimintahäiriöitila |
|
|
| Ongoing | 4 | 60 | Europe | Botulinum toxin A, Injection, Xeomin | Sitnikova Victoria, To the Brazilian agency Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior for financial support, based on the Postgraduate Social Demand Program in Health Sciences of the Faculdade de Medicina de Sao Jose do Rio Preto. | osteomuscular symptoms | | | | |
2010-018345-64: Evaluation of the efficacy of Xeomin in the treatment of cervical dystonia (CD) and blepharospasmus (BS) in patients who did not respond to treatment with Botox. |
|
|
| Ongoing | 4 | 30 | Europe | Powder for solution for injection, XEOMIN, BOTOX | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI | cervical dystonia, blepharospasmus (BS) | | | | |
2008-007626-19: Traitement par la toxine botulinique de la dystonie en griffe des orteils chez les patients parkinsoniens : Comparaison de l’efficacité d’injections effectuées dans la musculature extrinsèque (le long fléchisseur des orteils) et dans la musculature intrinsèque (la chair carrée/le court fléchisseur plantaire). |
|
|
| Ongoing | 4 | 45 | Europe | XEOMIN, XEOMIN | CHU Clermont-Ferrand | Patients parkinsoniens présentant une dystonie en griffe des orteils | | | | |
2009-013684-19: Studie av botulinumtoxiners anhidrotiska (svettreducerande) effekt beroende på använd koncentration. |
|
|
| Ongoing | 4 | 20 | Europe | Botox, Dysport, Xeomin, Neurobloc, Botox, Dysport, Xeomin, Neurobloc, Botox, Dysport, Xeomin, Neurobloc | Uppsala läns landsting | Studien kommer att utföras på friska försökspersoner. Anhidrotisk (svettreducerande) effekt samt durationen av denna kommer att undersökas efter injektioner med botulinumtoxin.Resultaten från studien kommer senare att appliceras vid behandling av patienter med sjukdomen hyperhidros. | | | | |
2012-002938-37: NA Comprobación del efecto clínico de tres toxinas botulínicas tipo A, sobre líneas verticales del entrecejo (líneas glabelares). |
|
|
| Ongoing | 4 | 60 | Europe | Vistabel, Bocouture, Azzalure, Vistabel, Bocouture, Azzalure, Vistabel®, Bocouture®, Azzalure®, Vistabel®, Bocouture®, Azzalure® | DR. JAVIER ANIDO RUBIO, Merz Pharma S.A | NA Se trata de sujetos que requieren tratamiento con toxina botulínica para las arrugas del entrecejo (líneas glabelares) de moderadas a profundas. | | | | |
2013-004293-10: Efficacy of treatment by iontophoresis of botulinum toxin type A free from complexing proteins for the excessive sweating of the stump Eficacia del tratamiento mediante iontoforesis de toxina botulínica tipo A sin proteínas complejantes para la excesiva sudoración del muñón de amputación |
|
|
| Ongoing | 4 | 18 | Europe | Botulinum neurotoxin type A free from complexing proteins, Xeomin, Xeomin | Hospital Universitari de Tarragona Joan XXIII, Merz Pharma España S.L. | Stump hyperhidrosis in lower limb amputees Hiperhidrosis del muñón de amputación de extremidades inferiores | | | | |
2016-001378-13: A randomized, sham-controlled trial which compare the deep brain stimulation of a specific brain region against a conventional botulinum toxine treatment for cervical dystonia. Eine randomisierte, scheinkontrollierte Studie, die die tiefe Hirnstimulation eine speziellen Hirnregion mit einer herkömmlichen Botulinumtoxintherapie bei zervikaler Dystonie vergleicht. |
|
|
| Not yet recruiting | 4 | 66 | Europe | Botulinumtoxin Type A, Powder for solution for injection, Botox(R) 50, Botox(R) 100, Botox(R) 200, Dysport(R) 300, Dysport(R) 500, XEOMIN(R) 50, XEOMIN(R) 100 | University Hospital Wuerzburg, Federal Ministry of Education and Research (BMBF), Medtronic GmbH | cervical dystonia zervikale Dystonie, Torticollis spasmodicus Schief- bzw. Fehlhaltung des Halses, Diseases [C] - Nervous System Diseases [C10] | | | | |
2017-003117-25: Muscular changes after injection of Botulinumtoxin illustrated by Magnetic Resonance Tomography over a period of 16 weeks and the impact of muscle before injection Der Einfluss von Bewegung auf die Wirkung von Botulinumtoxin und die Darstellung von muskulären Veränderungen des Muskels mittels Magnetresonanztomographie |
|
|
| Ongoing | 4 | 28 | Europe | Xeomin, Powder and solution for solution for injection, Xeomin | Medical University of Vienna | Spastic hemiparesis with involvement of the M. biceps brachii, Subjects with constraint movability after e.g. a stroke with increased muscle tone, Body processes [G] - Physiological processes [G07] | | | | |
NCT06250543: Evaluation of Intradetrusor AbobotulinumtoxinA and IncobotulinumtoxinA in Women With Overactive Bladder |
|
|
| Completed | 4 | 64 | Europe | AbobotulinumtoxinA 300 UNT, IncobotulinumtoxinA 100 UNT, Lidocain, placebo | Niko Kavcic | Overactive Bladder | 11/22 | 11/22 | | |
2018-001912-31: Treatment of headache attributed to temporomandibular disorder with a flat plane occlusal splint and injections of botulinum toxin Zdravljenje glavobola v zvezi s temporomandibularno motnjo z Michigansko okluzijsko opornico in injekcijami botulinum toksina |
|
|
| Not yet recruiting | 4 | 120 | Europe | Botox, Powder for suspension for injection, XEOMIN 100 units powder for solution for injection | UNIVERSITY MEDICAL CENTRE LJUBLJANA, UNIVERSITY MEDICAL CENTRE LJUBLJANA | Headache attributed to temporomandibular disorder Glavobol v zvezi s temporomandibularno motnjo, Headache caused by a disorder involving structures in the temporomandibular region. Glavobol, ki ga povzroča motnja, ki vključuje strukture v temporomandibularni regiji., Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
| Recruiting | 4 | 340 | RoW | IncobotulinumtoxinA 50 U Intramuscular Powder for Solution, Xeomin, Lateral subcutaneous sphincterotomy. | State Scientific Centre of Coloproctology, Russian Federation, St. Petersburg State Pavlov Medical University, Astrakhan State Medical University, Siberian State Medical University, City Clinical Hospital №24, Department of Health City of Moscow, GBUZ MO "Lvovskaia Raionaia Bolnica", Medical Center ON-CLINIC | Fissure in Ano | 09/22 | 11/22 | | |
2022-002192-11: Selän alueen poikkeava aktiivisuus servikaalisessa dystoniassa Selän alueen poikkeava aktiivisuus servikaalisessa dystoniassa |
|
|
| Not yet recruiting | 4 | 200 | Europe | Botuliinitoksiini, Concentrate and solvent for solution for injection, Botox /Xeomin | Pirkanmaan sairaanhoitopiiri, Pirkanmaan sairaanhoitopiiri | Servikaalinen dystonia, jossa poikkeavaa lihasaktiivisuutta esiintyy kaulan alueen lihaksissa aiheuttaen tyypillisiä virheasentoja kuten pään kiertymistä, kallistumista ja vapinaa. Servikaalista dystoniaa hoidetaan ensisijaisesti paikallisesti botuliinitoksiinipistoksilla, jossa poikkeavaa lihasaktiivisuutta pyritään vähentämään lamaamalla kohdelihasten toimintaa. Servikaalinen dystonia, jossa poikkeavaa lihasaktiivisuutta esiintyy kaulan alueen lihaksissa aiheuttaen tyypillisiä virheasentoja kuten pään kiertymistä, kallistumista ja vapinaa. Servikaalista dystoniaa hoidetaan ensisijaisesti paikallisesti botuliinitoksiinipistoksilla, jossa poikkeavaa lihasaktiivisuutta pyritään vähentämään lamaamalla kohdelihasten toimintaa., Servikaalinen dystonia, jossa poikkeavaa lihasaktiivisuutta esiintyy kaulan alueen lihaksissa aiheuttaen tyypillisiä virheasentoja kuten pään kiertymistä, kallistumista ja vapinaa Servikaalinen dystonia, jossa poikkeavaa lihasaktiivisuutta esiintyy kaulan alueen lihaksissa aiheuttaen tyypillisiä virheasentoja kuten pään kiertymistä, kallistumista ja vapinaa, Diseases [C] - Nervous System Diseases [C10] | | | | |
| Not yet recruiting | 4 | 6 | Europe | Incobotulinumtoxin A (BTX A) Xeomin® | Dominik Ettlin, Merz Pharmaceuticals | Sleep Bruxism, Adult | 12/22 | 06/23 | | |
NCT05536570: Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin. |
|
|
| Not yet recruiting | 4 | 15 | Canada | IncobotulinumtoxinA 100 UNT | King, David, MD, MERZ PHARMA | Thoracic Outlet Syndrome, Whiplash Injuries | 04/23 | 06/23 | | |
| Recruiting | 4 | 20 | US | Xeomin®, IncobotulinumtoxinA | Wake Forest University Health Sciences, Merz Pharmaceuticals GmbH | Stroke | 04/26 | 04/26 | | |
2021-001634-18: A clinical study to investigate the efficacy and safety of NT 201 in the treatment of lower limb spasticity in children and adolescents with cerebral palsy Badanie kliniczne mające na celu zbadanie skuteczności i bezpieczeństwa stosowania NT 201 w leczeniu spastyczności kończyn dolnych u dzieci i młodzieży z mózgowym porażeniem dziecięcym |
|
|
| Not yet recruiting | 3 | 130 | Europe | NT 201, NT 201, Powder for solution for injection, Xeomin | Merz Pharmaceuticals GmbH, Merz Pharmaceuticals GmbH | Pediatric lower limb (LL) spasticity (SP) caused by cerebral palsy (CP) Spastyczność kończyn dolnych u dzieci z mózgowym porażeniem dziecięcym., Pediatric lower limb spasticity caused by cerebral palsy. Spastyczność kończyn dolnych u dzieci z mózgowym porażeniem dziecięcym., Diseases [C] - Nervous System Diseases [C10] | | | | |
2013-005088-13: Blocs partiels du droit antérieur et du soléaire avec la toxine botulique de type A (Xeomin®) pour l'amélioration de la marche chez l'hémiparétique. Essai randomisé multicentrique contrôlé contre placebo. |
|
|
| Not yet recruiting | 3 | 66 | Europe | XEOMIN, Powder for injection, XEOMIN | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP) | Hémiparésie par accident vasculaire cérébral (AVC) ou traumatise crânien (TC) depuis plus de 6 mois. | | | | |
2015-003184-11: Functional effects of botulinum toxin in the hip adductors and subsequent exercise in HSP patients Functionele effecten van botulinetoxine in de heup adductoren en daaropvolgende oefeningen bij HSP patiënten. |
|
|
| Ongoing | 3 | 30 | Europe | Solution for injection, Xeomin | Radboud University Medical Centre, Radboud University Medical Centre | Hereditary Spastic Paraplegia Hereditaire Spastische Paraplegie, HSP HSP, Diseases [C] - Nervous System Diseases [C10] | | | | |
2017-001216-11: botulinum toxin for the treatment of chronic anal fissure Toxina botulínica para el tratamiento de la fisura anal crónica |
|
|
| Ongoing | 3 | 100 | Europe | IncobotulinumtoxinA, IncobotulinumtoxinA, Powder for solution for injection, Xeomin® | Dra. A. Teresa Calderón Duque, NA | Chronic anal fissure Fisura anal crónica, Chronic anal fissure Fisura anal crónica, Not possible to specify | | | | |
2016-000740-34: Treatment of continuous tearing with Botulinum Toxin versus the inferior eyelid tightening technique Tratamiento del lagrimeo continuo con Toxina Botulínica frente a la técnica de tensado del párpado inferior |
|
|
| Ongoing | 3 | 24 | Europe | IncobotulinumtoxinA, IncobotulinumtoxinA, Powder and solution for solution for injection, Xeomin® | Dr. Borja Maroto Rodríguez, NA | Functional Epifora Epífora funcional, Continuous tearing Lagrimeo continuo, Diseases [C] - Eye Diseases [C11] | | | | |
| Not yet recruiting | 3 | 150 | Europe | Xeomin, Hydrocortancyl, Powder for injection, Suspension for injection, Xeomin, Hydrocortancyl | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), DGOS | Patients suffering from unilateral lateral epicondylitis, persistent for more than 3 months or recurrent and not having responded to at least one reference treatment Patients ayant une épicondylite latérale unilatérale, persistante depuis plus de 3 mois ou récidivante et n'ayant pas répondu à au moins un traitement de référence, NA NA, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2016-003949-28: Efficacy and tolerability of incobotulinumtoxin A in comparison with onabotulinumtoxinA in patients with overactive bladder syndrome. Efficacia e tollerabilit¿ della incobotulinumtoxin A in confronto alla onabotulinumtoxin A nella terapia di pazienti con vescica iperattiva. |
|
|
| Not yet recruiting | 3 | 140 | Europe | xeomin, botox, Powder for solution for injection, XEOMIN - 100 UNITA' DL50 POLVERE PER SOLUZIONE INIETTABILE 1 FLACONCINO DI VETRO, BOTOX - 100 UNIT¿ ALLERGAN POLVERE PER SOLUZIONE INIETTABILE 1 FLACONCINO | PROF. ANTONELLA GIANNANTONI - CLINICA UROLOGICA - UNIVERSITà DI PERUGIA, Clinica Urologica ad indirizzo Oncologico | neurogenic overactive bladder Vescica iperattiva neurogena, neurogenic overactive bladder Vescica iperattiva neurogena, Diseases [C] - Symptoms and general pathology [C23] | | | | |
2018-002929-36: EFFICACY OF CORTICOIDS VS BOTULINIC TOXIN IN THE TREATMENT OF PLANTAR FASCITIS EFICACIA DE CORTICOIDES VS TOXINA BOTULÍNICA EN EL TRATAMIENTO DE LA FASCITIS PLANTAR |
|
|
| Not yet recruiting | 3 | 70 | Europe | IncobotulinumtoxinA, Triamcinolona acetónido, IncobotulinumtoxinA, Triamcinolona acetónido, Powder for solution for injection, Suspension for injection, Xeomin®, TRIGON DEPOT® | Dra. Virginia Raquel Céspedes Nava, NA | Plantar fasciitis Fascitis plantar, Plantar fasciitis Fascitis plantar, Body processes [G] - Physical Phenomena [G01] | | | | |
2018-002541-11: Prevention of post-operative Atrial Fibrillation by BOTulinum toxin injections into epicardial fat pads around pulmonary veins in patients undergoing cardiac surgery Prévention de la Fibrillation Atriale postopératoire par l’injection de Toxine BOtulique autour des veines pulmonaires chez les patients ayant une chirurgie cardiaque |
|
|
| Not yet recruiting | 3 | 220 | Europe | XEOMIN, Powder for solution for injection, Xeomin® 200 U | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), Ministry of Health | Adult patients with indication for conventional cardiac surgery (CABG, aortic replacement, or ascending aorta surgery) will be eligible Seront éligibles : les patients adultes (>/= 18 ans) avec indication à une chirurgie cardiaque selon les recommandations de la Société Européenne de Cardiologie (ESC) : pontages coronaires, remplacements valvulaires aortiques, remplacements de l’aorte ascendante, Adult patients with indication for conventional cardiac surgery Patients adultes avec indication à une chirurgie cardiaque selon les recommandations de la Société Européenne de Cardiologie, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
NCT03758235: Overactive Bladder Syndrome: Incobotulinumtoxin Versus Onabotulinumtoxin |
|
|
| Active, not recruiting | 3 | 140 | Europe | IncobotulinumtoxinA 100 UNT Injection [Xeomin], Incobot/A, OnabotulinumtoxinA 100 UNT [Botox], Onabot/A | University Of Perugia | Overactive Bladder Syndrome | 09/21 | 09/21 | | |
2022-000842-14: Effectiveness of botulinum toxin A injection in reducing the pain and size of painful scars Efectividad de la inyección de toxina botulínica A para reducir el dolor y tamaño de las cicatrices dolorosas |
|
|
| Not yet recruiting | 3 | 20 | Europe | IncobotulinumtoxinA, IncobotulinumtoxinA, Powder for solution for injection, Xeomin® | Dra.Margarita Ramirez&Dra.Ifara Sánchez, NA | painful scars Cicatrices dolorosas, painful scars Cicatrices dolorosas, Not possible to specify | | | | |
2019-004113-13: Safety and efficacy study of the simultaneous treatment of upper facial lines (horizontal forehead lines, glabellar frown lines and crows feet) in subjects with moderate to severe upper facial lines. |
|
|
| Not yet recruiting | 3 | 360 | Europe | Bocouture, NT 201, Powder for solution for injection, Bocouture (100 Units) | Merz Pharmaceuticals GmbH, Merz Pharmaceutical GmbH | Moderate to severe upper facial lines(horizontal forehead lines, glabellar frown lines, and lateral canthal lines), Moderate to severe upper facial lines(horizontal forehead lines, glabellar frown lines, and crows feed Falten des oberen Gesichtsbereiches(horizontale Stirnfalten, Zornesfalten und Krähenfüße), Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
| Recruiting | 3 | 220 | Europe | Botulinum Toxin Type A Injection [Xeomin], Xeomin, Drug placebo | Assistance Publique - Hôpitaux de Paris, Merz Pharmaceuticals, Ministry of Health, France | Cardiac Surgery | 10/24 | 09/25 | | |
2020-006147-25: Botulinum toxin type A injection in patients with chronic pelvic pain of uterine origin Phase III, single-center, randomized study vs. control group Injection de Toxine botulinique de type A chez des patientes atteintes de douleurs pelviennes chroniques d’origine utérine Étude de phase III, monocentrique, randomisée vs groupe contrôle |
|
|
| Ongoing | 3 | 100 | Europe | Toxine botulinique, Powder for solution for injection, XEOMIN 200 | Centre de Recherche en Santé de la Femme, Centre de Recherche en Santé de la Femme, Laboratoire MERZ | PATIENTS WITH CHRONIC PELVIC PERINEAL PAIN OF UTERINE ORIGIN WITH VAS>4 PATIENTES PRÉSENTANT DES DOULEURS PELVI-PERINEALES CHRONIQUES D'ORIGINE UTÉRINE AVEC EVA>4, PATIENTS WITH CHRONIC PELVIC PERINEAL PAIN OF UTERINE ORIGIN WITH VAS>4 PATIENTES PRÉSENTANT DES DOULEURS PELVI-PERINEALES CHRONIQUES D'ORIGINE UTÉRINE AVEC EVA>4, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] | | | | |
NCT05623410: Study to Compare the Efficacy and Safety of ATGC-110 (Botulinum Toxin) With Xeomin® for the Treatment of Moderate to Severe Glabellar Frown Lines |
|
|
| Active, not recruiting | 3 | 300 | RoW | ATGC-110, Clostridium Botulinum Type A, Xeomin®, Incobotulinumtoxin A | ATGC Co., Ltd. | Glabellar Frown Lines | 02/23 | 06/23 | | |
2022-004127-40: effectiveness and safety of botulinum toxin type A in doses adapted for patients with severe spasticity efectividad y seguridad de la toxina botulínica tipo A en dosis adaptadas para pacientes con cuadros de espasticidad severa |
|
|
| Not yet recruiting | 3 | 30 | Europe | IncobotulinumtoxinA, IncobotulinumtoxinA, Powder for solution for injection, Xeomin | Dra. Nuria Gutierrez Dubón, NA | brain damage oriented spasticity Espasticidad orientada al daño cerebral, spasticity Espasticidad, Not possible to specify | | | | |
NCT05980559: Evaluation of BTX Injections in Treatment of Bruxism |
|
|
| Not yet recruiting | 3 | 12 | NA | Xeomin | Alexandria University | Bruxism | 01/24 | 04/24 | | |
NCT03977493: IncobotulinumtoxinA (Xeomin) to Treat Focal Hand Dystonia |
|
|
| Recruiting | 3 | 48 | Europe | Xeomin, Placebo - Concentrate | Alain Kaelin, Clinical Trial Unit Ente Ospedaliero Cantonale | Focal Hand Dystonia | 12/24 | 12/24 | | |
NCT06205797: To Evaluate HU-045 in the Treatment of Glabellar Lines(Phase III) |
|
|
| Not yet recruiting | 3 | 312 | NA | HU-045, Xeomin® | Huons Biopharma | Glabellar Lines | 09/24 | 07/25 | | |
| Recruiting | 3 | 128 | US | IncobotulinumtoxinA (XEOMIN®), Xeomin, OnabotulinumtoxinA (BOTOX®), Botox | Naval Medical Center Camp Lejeune | Chronic Migraine | 02/25 | 08/25 | | |
PATTERN, NCT03992404 / 2018-001639-35: Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury |
|
|
| Recruiting | 3 | 600 | Europe, US, RoW | NT 201, IncobotulinumtoxinA, Incobotulinumtoxin A, Xeomin, Botulinum toxin type A (150 kiloDalton), free from complexing proteins, Placebo | Merz Pharmaceuticals GmbH | Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury | 08/25 | 04/27 | | |
2021-003315-25: Botulinum toxin and degenerative rotator cuff tendinopathies: a randomized trial »DEROTOX (DEgenerative ROtator cuff disease and botulinum TOXin) Toxine botulique et tendinopathies dégénératives de la coiffe des rotateurs : un essai randomisé » DEROTOX (DEgenerative ROtator cuff disease and botulinum TOXin) |
|
|
| Ongoing | 2 | 60 | Europe | XEOMIN, Powder for solution for injection, XEOMIN 100 units powder for solution for injection | , ASSISTANCE PUBLIQUE – HÔPITAUX DE PARIS - Direction de la Recherche Clinique et de l’Innovation | Degenerative tendinopathies of the rotator cuff Tendinopathies dégénératives de la coiffe des rotateurs, Diseases of the tendons of the patella of the shoulder Maladies des tendons de la rotule de l'épaule, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2014-002210-23: Can local botulinum toxin improve swallowing difficulties in persons with msucle disease? |
|
|
| Ongoing | 2 | 15 | Europe | Xeomin, Concentrate and solvent for solution for injection, Xeomin | Rigshospitalet, Rigshospitalet | Oculopharyngesl muscle dystrophy, inclusion body myositis, 2 muscle diseases with pronounced swallowing difficulties, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2007-006268-32: EFFICACY AND SAFETYOF BOTULINUM TOXIN THERAPY ON UPPER LIMB SPASTICITY IN INFLAMMATORY AND DEMIELINIZZATING DISEASE OF CENTRAL NERVOUS SYSTEM. |
|
|
| Ongoing | 2 | 40 | Europe | xeomin, xeomin | OSPEDALE S. RAFFAELE | multiple sclerosis | | | | |
2008-005632-32: INYECCIÓN FRECUENTE DE TOXINA BOTULÍNICA SIN PROTEÍNAS COMPLEJANTES: EVALUACIÓN DEL EFECTO SOBRE EL DOLOR EN DISTONÍA CERVICAL |
|
|
| Ongoing | 2 | 36 | Europe | XEOMIN 100 UNIDADES DL50 polvo para solución inyectable, XEOMIN 100 UNIDADES DL50 polvo para solución inyectable | Fundació privada de l\'Institut de Recerca de l\'Hospital de la Santa Creu i Sant Pau | Distonía Cervical | | | | |
2011-003646-41: Pilotstudy: application of botulinumtoxin A (Xeomin®) to investigate the efficacy and safety of NT 201 for the prophylaxis of relapse after advancement of the mandible Pilotstudie: Die Anwendung von Botulinumtoxin A (Xeomin®) zur Rezidivprophylaxe bei Unterkiefervorverlagerungen |
|
|
| Ongoing | 2 | 30 | Europe | Xeomin, Xeomin, Xeomin | Oliver Ploder MD, DDS, PhD, Merz Pharma Austria GmbH | The study will analyse the efficacy of BTX-A to avoid a relapse after advancement of the mandible (BSSO – bilateral sagittal split osteotomy) with more than 5 mm. The tension of the muscle complex of the anterior floor of the mouth can cause a relapse of the advancement of the mandible in the follow up. | | | | |
| Ongoing | 2 | 54 | Europe | Bocouture (Botulinumtoxin A), Powder for solution for injection, Bocouture | Medizinische Hochschule Hannover, Asklepios Klinik Nord, Medizinische Hochschule Hannover | Borderline personality disorder Borderline-Persönlichkeitsstörung, n.a., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-002127-10: Evaluation of pain after intra-articular injections of botulinum toxin in carpometacarpal osteoarthritis of the thumb Évaluation de la douleur après injections intra-articulaires de toxine botulique dans l'arthrose carpométacarpienne du pouce |
|
|
| Not yet recruiting | 2 | 60 | Europe | XEOMIN 50, Injection, XEOMIN 50 | CHU de Nice, CHU de Nice | Rhizarthrosis Rhizarthrose, Rhizarthrosis Rhizarthrose, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2020-001318-39: Simultaneous treatment of upper and two thirds of the face withIncobotulinumtoxinA applied intradermally (Interventional Phase II) |
|
|
| Ongoing | 2 | 40 | Europe | Bocouture, Bocouture, Powder for solution for injection, Bocouture | Prof. Dr. Martina Kerscher, University of Hamburg, Prof. Dr. Martina Kerscher, Universität of Hamburg | Skin perception after intradermal application of INCOBOTULINUMTOXINA within upper and midface, Change in skin surface roughness before and 4 weeks after intradermalinjection of IncobotulinumtoxinA(primary efficacy criterion)., Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
| Completed | 2 | 50 | RoW | HU-045, IncobotulinumtoxinA, Xeomin® | Huons Co., Ltd. | Glabellar Lines | 11/22 | 04/23 | | |
NCT04766723: A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm |
|
|
| Completed | 2 | 78 | Europe, Canada, US | NT 201, Incobotulinumtoxin A, IncobotulinumtoxinA, Xeomin, Botulinum toxin type A (150 kiloDalton), free from complexing proteins, Placebo | Merz Pharmaceuticals GmbH | Essential Tremor of the Upper Limb | 04/23 | 11/23 | | |
NCT05456087: Use of Botulinum Toxin in the Treatment of Androgenic Alopecia |
|
|
| Active, not recruiting | 2 | 20 | US | incobotulinumtoxin A, Xeomin | Zel Skin and Laser Specialists, Merz Aesthetics Inc. | Androgenetic Alopecia | 12/24 | 12/24 | | |
| Completed | 2 | 68 | US | NT 201, IncobotulinumtoxinA, Xeomin/Bocouture, Xeomin Cosmetic, Xeomeen, NT 201 Placebo | Merz Aesthetics GmbH | Platysma Prominence | 10/23 | 01/24 | | |
2021-001988-24: A Study to Investigate the Efficacy and Safety of NT201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm |
|
|
| Not yet recruiting | 2 | 75 | Europe | NT 201, NT 201, Powder for solution for injection, Xeomin | Merz Pharmaceuticals GmbH, Merz Pharmaceuticals GmbH | Essential tremor [ET] of the upper limb [UL], Essential tremor [ET] of the upper limb [UL], Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT03571334: Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy |
|
|
| Recruiting | 2 | 40 | US | IncobotulinumtoxinA (Xeomin®, Merz) (INA), Xeomin® (Brand name), Normal saline | Medical College of Wisconsin | Peripheral Neuropathy Due to Chemotherapy | 12/23 | 12/24 | | |
| Not yet recruiting | 2 | 30 | NA | IncobotulinumtoxinA 100 UNT [Xeomin] | Universita di Verona | Spastic Cerebral Palsy | 01/24 | 05/25 | | |
| Recruiting | 2 | 60 | NA | The investigational medicinal product is incobotulinumtoxinA (XEOMIN®)., PLACEBO | Assistance Publique - Hôpitaux de Paris, Merz Pharmaceuticals GmbH | Degenerative Rotator Cuff Disease | 02/27 | 02/27 | | |
NCT06034288: Xeomin vs Botox for Treatment of Overactive Bladder Syndrome |
|
|
| Recruiting | 2 | 64 | US | Xeomin 100 UNT Injection, incobotulinumtoxinA, Botox 100 UNT Injection, onabotulinumtoxinA | Walter Reed National Military Medical Center | Overactive Bladder Syndrome | 06/24 | 09/24 | | |
PaiNT, NCT06091020: A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury |
|
|
| Recruiting | 2 | 120 | Europe | IncobotulinumtoxinA, Xeomin, Botulinum toxin type A (150 kiloDalton), free from complexing proteins, NT 201, Placebo | Merz Therapeutics GmbH | Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury | 01/25 | 04/25 | | |
MENOX, NCT05196308: Efficacy of Intracavernosal as add-on Therapy to Sildenafil 100 mg on Demand Compared to Sildenafil 100 mg on Demand for the Treatment of Erectile Dysfunction (ED) Not Sufficiently Responsive to Standard Therapy With Phosphodiesterase Type 5 Inhibitors |
|
|
| Active, not recruiting | 2 | 226 | Europe | Investigational product administration Xeomin® (MERZ PHARMACEUTICALS GMBH), Placebo administration | Assistance Publique - Hôpitaux de Paris | Erectile Dysfunction | 03/25 | 03/25 | | |
NCT04965311: Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy |
|
|
| Recruiting | 2 | 63 | US | Botulinum Toxin Type A, AbobotulinumtoxinA, Botox, Botox Cosmetic, Botulinum A Toxin, Botulinum Neurotoxin Type A, Botulinum Toxin A, BTX-A, DaxibotulinumtoxinA, Dysport, EvabotulinumtoxinA, IncobotulinumtoxinA, OnabotulinumtoxinA, Onaclostox, Prabotulinumtoxin A, Xeomin | OHSU Knight Cancer Institute, Oregon Health and Science University | Pancreatic Carcinoma | 05/25 | 05/25 | | |
NCT04922983: Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis |
|
|
| Recruiting | 2 | 42 | US | Botulinum toxin type A, Incobotulinumtoxin A, Isometric Yoga-like exercise, Side-Plank, Vasisthasana, Placebo, no active intervention by drug or yoga-like exercise | Manhattan Physical Medicine and Rehabilitation, LLP | Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region | 07/25 | 01/26 | | |
PINBOT, NCT05623111: Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities |
|
|
| Recruiting | 2 | 80 | Europe | Incobotulinumtoxin-A 100 UNIT Injection, Saline | Rigshospitalet, Denmark, Merz Pharmaceuticals GmbH, Toyota Foundation Denmark, Steno Diabetes Center Zealand Region, Shipwright Per Henriksen, R., and wife Foundation | Diabetic Neuropathy, Painful | 11/25 | 02/26 | | |
NCT04030767: Evaluating Lip Repositioning for the Treatment of Excess Gingival Display With and Without Pretreatment With Botox |
|
|
| Not yet recruiting | 1 | 22 | NA | Botox Injectable Product, Xeomin | Cairo University | Gingival Overgrowth | 09/20 | 09/22 | | |
NCT05305768: Xeomin Treatment of Glabellar Lines Using OLD Versus COLD |
|
|
| Not yet recruiting | 1 | 40 | US | IncobotulinumtoxinA, Xeomin | Clinical Testing of Beverly Hills, Merz North America, Inc. | Glabellar Frown Lines | 02/23 | 02/23 | | |
NCT05585398: A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods |
|
|
| Completed | 1 | 40 | Europe | IncobotulinumtoxinA, Xeomin, Botulinum toxin type A (150 kiloDalton), free from complexing proteins | Merz Pharmaceuticals GmbH | N/A, as no Specific Medical Condition Will be Treated | 02/23 | 04/23 | | |
LESS, NCT05784363: A Study of NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the Face |
|
|
| Completed | 1 | 31 | US | NT 201, IncobotulinumtoxinA, Xeomin/Bocouture®, Xeomin Cosmetic, Xeomeen, Placebo | Merz North America, Inc. | Enlarged Pores, Sebum Production | 06/24 | 07/24 | | |
NCT04544280: Effect of Repeated Injections of Higher Doses of Botulinum Toxin on Lower Limb of Spastic Hemiplegic Patients on Gait. |
|
|
| Completed | N/A | 32 | Europe | Xeomin Injectable Product | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Stroke | 12/21 | 12/21 | | |
NCT05222607: Longitudinal Evaluation and Real-world Evidence of NT201 |
|
|
| Terminated | N/A | 11 | US | IncobotulinumtoxinA, XEOMIN®, BOCOUTURE® | Merz North America, Inc. | Glabellar Frown Lines and Canthal Lines and/or Horizontal Forehead Lines in the Upper Face | 05/23 | 05/23 | | |
XAVIER, NCT06345677: Clinical Trial for the Assessment of Safety, Usability and Efficacy of the Vixe Combination for OAB in Female Subjects |
|
|
| Completed | N/A | 48 | Europe | ViXe Xombination, Placebo + Sham | Vensica Therapeutics Ltd., Blueclinical, Ltd. | Overactive Bladder | 02/24 | 02/24 | | |
JBDX, NCT05167864: Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area |
|
|
| Completed | N/A | 143 | US | Onabotulinumtoxina for Injection, Botox, Abobotulinumtoxina for Injection, Dysport, IncobotulinumtoxinA for Injection, Xeomin, PrabotulinumtoxinA for Injection, Jeuveau | University of Pennsylvania | Cosmetic Techniques | 06/23 | 06/23 | | |
NCT02019004: A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles |
|
|
| Active, not recruiting | N/A | 20 | US | Onabotulinum Toxin A, Botox, Incobotulinum Toxin A, Xeomin | Northwestern University | Wrinkles | 12/24 | 12/24 | | |
| Completed | N/A | 270 | Europe | CC BoNT/A, onabotulinumtoxinA, abobotulinumtoxinA, CF BoNT/A, incobotulinumtoxinA, NT 201, Botulinum toxin type A (150 kiloDalton), free from complexing proteins, CF to CC BoNT/A, CC to CF BoNT/A | Merz Therapeutics GmbH, Heinrich-Heine University, Duesseldorf | Cervical Dystonia | 05/24 | 07/24 | | |
| Recruiting | N/A | 52 | RoW | Baclofen 10mg, Baclosan, Botulinum toxin type A, Botox, Xeomin, Dysport | Saint Petersburg State University, Russia, Ural State Medical University | Chronic Pain, Chronic Pelvic Pain Syndrome, Myofascial Pain Syndrome, Myofascial Trigger Point Pain, Pelvic Floor Disorders | 12/23 | 05/24 | | |
NCT06386848: Strategy to Adapt Botulinum Toxin Doses in Dystonia |
|
|
| Not yet recruiting | N/A | 100 | NA | Botulinum toxin, onabotulinumtoxinA, abobotulinumtoxinA, incobotulinumtoxinA | Central Hospital, Nancy, France | Dystonia | 05/24 | 06/24 | | |
| Recruiting | N/A | 12 | Europe | Botulinum toxin type A, Xeomin | Region Zealand | Neuralgia, Chronic Pain | 11/24 | 12/24 | | |
NCT05604729: The Effect on Envelope of Motion in Asymptomatic Bruxers |
|
|
| Recruiting | N/A | 60 | Europe | Botulinum toxin type A, Xeomin, Placebo, Isotonic solution | Region Västerbotten, Umeå University | Tooth Wear, Bruxism | 12/24 | 12/25 | | |