megestrol / Generic mfg.  >>  Phase 2
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
megestrol / Generic mfg.
PIONEER, NCT03306472 / 2016-003752-79: A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer

Completed
2
198
Europe
Megestrol Acetate 40 MG, Megace, Megestrol Acetate 160 MG, Letrozole
Cambridge University Hospitals NHS Foundation Trust, Anticancer Fund, Belgium
Breast Cancer
10/22
10/23
2020-004530-38: PROSPECTIVE, PHASE II STUDY TO EVALUATE THE EFFICACY OF ADDITION OF PROGESTERONE TO STANDARD CHEMOTHERAPY ACCORDING TO EDP SCHEME PLUS MITOTANE IN PATIENTS WITH ADVANCED ADRENAL CORTICAL (PESETA TRIAL) Studio prospettico, di fase II volto a valutare l’efficacia dell’aggiunta di progesterone alla chemioterapia standard secondo schema EDP + mitotane nei pazienti affetti da carcinoma della corticale del surrene avanzato.

Not yet recruiting
2
80
Europe
megace, [megace], Tablet, MEGACE - 160 MG COMPRESSE 30 COMPRESSE
AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA, UNIVERSITA' DEGLI STUDI DI BRESCIA_ BANDO AIRC
advanced/ metastatic patients with ACC carcinoma della corticale del surrene avanzato, advanced/ metastatic patients with ACC carcinoma della corticale del surrene avanzato, Diseases [C] - Cancer [C04]
 
 
NCT05380479: Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.

Recruiting
2
80
RoW
Mirtazapine, Megestrol Acetate
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Anorexia
01/23
02/23
NCT05492487: A Pilot Study on Fertility Conservative Treatment of Atypical Endometrial Hyperplasia in Singapore

Recruiting
2
60
RoW
Mirena, Megace
KK Women's and Children's Hospital
Endometrial Hyperplasia, Fertility Issues, Disease Regression, Treatment Side Effects
03/23
03/23
NCT04491643: Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

Recruiting
2
48
RoW
Megestrol Acetate, Rosuvastatin
Fudan University
Endometrial Carcinoma Stage I
08/25
08/25
NCT03671811: Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

Active, not recruiting
2
44
US
Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC-10363, Pterostilbene, 3'',5''-Dimethoxy-4-stilbenol, 3,5-Dimethoxy-4''-hydroxystilbene, Trans-3,5-dimethoxy-4-hydroxystilbene
City of Hope Medical Center, National Cancer Institute (NCI)
Atypical Endometrial Hyperplasia, Endometrial Carcinoma
11/24
11/24
NCT05247268: Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole in Young Women with Early Endometrial Cancer

Recruiting
2
104
RoW
Megestrol Acetate 160 MG Oral Tablet, Megestrol Acetate, Medroxyprogesterone Acetate 500 MG, Medroxyprogesterone Acetate, Triprorelin Acetate, Letrozole 2.5mg, Letrozole
Fudan University, Peking Union Medical College Hospital
Endometrial Neoplasm Malignant Stage I
03/25
03/25
NCT04576104: Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Recruiting
2
50
US
Biopsy, BIOPSY_TYPE, Bx, Extended Release Metformin Hydrochloride, ER Metformin Hydrochloride, Extended-release Metformin Hydrochloride, Glucophage XR, Glumetza, Metformin Hydrochloride Extended Release, Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC 10363, SC-10363, Questionnaire Administration
National Cancer Institute (NCI)
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Carcinoma
11/24
11/24
ChiCTR2200055624: Levonorgestrel-releasing intrauterine device and megestrol acetate plus metformin for fertility-sparing treatment of atypical endometrial hyperplasia and endometrial carcinoma: a prospective, randomised, blinded-endpoint design trial protocol

Recruiting
2
80
 
LNG-IUD plus metformin ;megestrol acetate plus metformin
Shenyang Women's and Children's Hospital; Level of the institution:, Shenyang Young and Middle-Aged Scientific and Technological Innovation Talents Support Program
atypical endometrial hyperplasia and endometrial carcinoma
 
 
PESETA, NCT05913427: Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC)

Recruiting
2
80
Europe
Etoposide, doxorubicin, cisplatin and Mitotane plus Megestrol Acetate 160 MG, Megace, Etoposide, doxorubicin, cisplatin and Mitotane plus Placebo, placebo
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Adrenocortical Carcinoma
06/27
06/27
NRG-GY028, NCT05538897: Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Recruiting
1/2
96
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Ipatasertib, GDC 0068, GDC-0068, GDC0068, RG 7440, RG-7440, RG7440, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC 10363, SC-10363
National Cancer Institute (NCI), NRG Oncology
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Metastatic Endometrial Endometrioid Adenocarcinoma, Recurrent Endometrial Endometrioid Adenocarcinoma, Stage IV Uterine Corpus Cancer AJCC v8
01/27
01/27

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