| sildenafil / Generic mfg. |
ChiCTR2000037331: AI-assisted diagnosis and treatment engine based on a fully structured congenital diaphragmatic hernia disease database |
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| Recruiting | N/A | 200 | | sildenafil + conventional therapy ;conventional therapy | Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine; Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai Shenkang Hospital Development Center | Congenital diaphragmatic hernia | | | | |
| Withdrawn | N/A | 100 | Canada | Sildenafil | University of British Columbia | Renal Transplant Failure | 01/23 | 01/23 | | |
NCT05546125: a Non-interventional Study of Sildenafil in the Treatment of Pulmonary Arterial Hypertension (PAH) in Adults From China |
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| Completed | N/A | 100 | RoW | as per Physician's prescription | Pfizer Pharmaceuticals Ltd. | Pulmonary Arterial Hypertension (PAH) | 02/23 | 02/23 | | |
HEXASH, NCT04697862: Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil |
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| Completed | N/A | 24 | Europe | Normobaric hypoxia (FiO2 15%) under Sildenafil, Normobaric hypoxia (FiO2 15%) | University of Zurich | Hypertension, Pulmonary | 05/23 | 05/23 | | |
HEXAS, NCT04704440: Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension With/Without Sildenafil |
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| Completed | N/A | 24 | Europe | Normobaric hypoxia (FiO2 15%), Placebo-ambient air (FiO2 21%), Normobaric hypoxia (FiO2 15%) under Sildenafil, Placebo-ambient air (FiO2 21%) under Sildenafil | University of Zurich | Hypertension, Pulmonary | 05/23 | 05/23 | | |
HEXASN, NCT04706546: Hemodynamic Effects During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil |
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| Completed | N/A | 24 | Europe | Hemodynamic effect of exercise under Sildenafil, Hemodynamic effect of exercise | University of Zurich | Hypertension, Pulmonary | 05/23 | 05/23 | | |
HEXABM, NCT04715113: Blood Markers Predict Effect of Normobaric Hypoxia at Rest and During Exercise in Patients With Pulmonary Hypertension |
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| Completed | N/A | 24 | Europe | Normobaric hypoxia (FiO2 15%), Placebo-ambient air (FiO2 21%), Normobaric hypoxia (FiO2 15%) under Sildenafil, Placebo-ambient air (FiO2 21%) under Sildenafil | University of Zurich | Hypertension, Pulmonary | 05/23 | 05/23 | | |
PRISM, NCT05946681: Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings |
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| Completed | N/A | 1017 | RoW | | NICHD Global Network for Women's and Children's Health, Global Network for Women's and Children's Health Research, University of Alabama at Birmingham, University Teaching Hospital, Lusaka, Zambia, RTI International | Fetal Distress, Perinatal Asphyxia, Birth Asphyxia, Stillbirth | 10/23 | 12/23 | | |
| Completed | N/A | 16 | Europe | Sildenafil, Placebo | Danish Headache Center, Novartis | Migraine Without Aura | 10/23 | 10/23 | | |
NCT05669885: Hypersensitivity to Phosphodiesterase 5 Inhibition in Post-Traumatic Headache |
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| Recruiting | N/A | 21 | Europe | Sildenafil, Placebo | Danish Headache Center | Post-Traumatic Headache | 12/23 | 12/23 | | |
NCT06237751: Preoperative Sildenafil Administration for Hepatectomy |
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| Recruiting | N/A | 16 | RoW | Sildenafil 100 MG, nitroglycerine | First People's Hospital of Chenzhou | Central Venous Pressure, Hepatectomy, Hemodynamics Instability, Sildenafil | 10/24 | 12/24 | | |
NCT04344678: The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients |
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| Recruiting | N/A | 100 | RoW | Sildenafil Citrate, Placebo oral tablet | Sadat City University | Major Depressive Disorder | 10/24 | 12/24 | | |
ACTRN12611000267954: Effect of preoperative sildenafil on patients with severe pulmonary hypertension undergoing heart valve replacement. |
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| Not yet recruiting | N/A | 50 | | | Richard Renew, Waikato Hospital | Pulmonary Hypertension, Valvular Heart Disease | | | | |
NCT04379180: Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN |
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| Not yet recruiting | N/A | 500 | RoW | Bosentan Tablets, Sildenafil Tablet, Tadalafil Tablets | Shandong University, West China Second University Hospital | Persistent Pulmonary Hypertension of the Newborn | 02/23 | 05/23 | | |