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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
dacarbazine / Generic mfg.
ACTRN12612000137897: Dose-Dense ABVD Study: An accelerated delivery of Adriamycin, Bleomycin, Vinblastin and Dacarbazine for patients with Hodgkin Lymphoma

Not yet recruiting
2
31
 
Queensland Health, Hospira
Early Stage Unfavourable Hodgkin Lymphoma, Advanced Stage Hodgkin Lymphoma
 
 
ACTRN12608000639325: Multicentre clinical study with early treatment intensification in patients with high-risk Hodgkin Lymphoma, identified as 18-F Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) scan positive after two conventional Doxorubicin, Bleomycin, Vinblastine, Dacarbazine (ABVD) courses

Recruiting
2
450
 
Gruppo Italiano Terapie Innovative nei Linfomi (GITIL), Gruppo Italiano Terapia Innovativa nei Linfomi
Hodgkin Lymphoma
 
 
R-2, NCT05898451: Effect of Refnot on Immunity in Cancer Patients

Completed
2
55
NA
Tumor necrosis factor-thymosin alfa 1 recombinant (TNF-T), Refnot, Tumor necrosis factor-thymosin alfa 1 recombinant, Tumor necrosis factor-thymosin alfa 1 recombinant (TNF-T) and chemotherapy, and Dacarbazine, Lomustine, Cisplatin
Refnot-Pharm Ltd
Solid Tumor
11/11
11/11
2014-001303-52: Treatment of relapsed/refractory leukemia with intravenous administration of Dacarbazine Trattamento della leucemia acuta mieloide recidivata/refrattaria con somministrazione endovenosa di Dacarbazina

Ongoing
2
20
Europe
DACARBAZINA, Powder for solution for infusion, DACARBAZINA
Azienda Ospedaliero-Universitaria di Parma, medac pharma srl, Fondo dipartimento università degli studi di Parma
Relapsed/Refractory acute myeloid leukemia patients Pazienti affetti da leucemia acuta mieloide recidivata/refrattaria, Relapsed/Refractory acute myeloid leukemia patients Pazienti affetti da leucemia acuta mieloide recidivata/refrattaria, Diseases [C] - Blood and lymphatic diseases [C15]
 
 
2007-007265-20: A Phase II open label randomized parallel group non comparative trial to assess efficacy and safety of the association of IPH1101 and IL-2 alone and in combination with dacarbazine, in patients with metastatic melanoma

Ongoing
2
6
Europe
Phosphostim 200, PROLEUKIN 18 MUI, Dacarbazine Mayne 600 mg, IPH1101, DTIC, PROLEUKIN 18 MUI, Dacarbazine Mayne 600 mg, poudre pour solution injectable, PROLEUKIN 18 MUI, Dacarbazine Mayne 600 mg, poudre pour solution injectable
Innate Pharma
metastatic melanoma
 
 
2007-007168-94: PHASE II MULTICENTRE CLINICAL STUDY WITH EARLY TREATMENT INTENSIFICATION IN PTS WITH HIGH-RISK HODGKIN LYMPHOMA, IDENTIFIED AS FDG-PET SCAN POSITIVE AFTER TWO CONVENTIONAL ABVD COURSES

Ongoing
2
450
Europe
Dacarbazine, ADRIBLASTINA, BLEOMICINA CRIN, VINBLASTINA BAX, ADRIBLASTINA, BLEOMICINA CRIN, VINBLASTINA BAX
AZIENDA OSPEDALIERA \"S. CROCE E CARLE\"
HD ADVANCED DISEASE
 
 
2010-021885-31: Randomized Phase II Study Using a Non-myeloablative Lymphocyte Depleting Regimen of Chemotherapy Followed by Infusion of Tumor Infiltrating Lymphocytes and Interleukin-2 in Metastatic Melanoma’

Ongoing
2
45
Europe
Tumor Infiltrating Lymphocytes, TIL, dacarbazine, dacarbazine
NKI-AVL
Patients with metastatic (stage IV) melanoma will be randomized to either treatment arm A (dacarbazine) or treatment arm B (TIL) after metastasectomy and feasibility of culturing of TIL.
 
 
2012-001020-35: A clinical phase II trial to compare the efficacy of Bevacizumab monotherapy with standard chemotherapy (dacarbazine) in metastatic melanoma. En fase 2 studie for å sammenligne effekten av Bevacizumab monoterapi med standard kjemoterapi (dacarbazine) ved malignt melanom med metastaser.

Ongoing
2
120
Europe
Bevacizumab, Dacarbazine, Inderal, Renitec, 091652, Avastin (Bevacizumab), Dacarbazine, Inderal (Propranolol), Renitec (Enalapril), Avastin (Bevacizumab), Dacarbazine, Inderal (Propranolol), Renitec (Enalapril)
Helse Bergen HF, Haukeland University Hospital, The Norwegian Cancer Association
Previously treated or untreated histologically confirmed metastatic and unresectable melanoma with radiological (RECIST), clinical or biochemical progressive disease.
 
 
2007-006713-16: Phase II Randomized, Open-Label Study of IMC-1121B With or Without Dacarbazine in Patients with Metastatic Malignant Melanoma

Ongoing
2
10
Europe
IMC-1121B, Dacarbazine, IMC-1121B,
ImClone Systems Incorporated
Metastatic Malignant Melanoma
 
 
2017-001207-68: A study to investigate the efficacy of ramucirumab in combination with dacarbazine in patients with progressive well-differentiated metastatic neuroendocrine tumors of the pancreas Studie zur Untersuchung der Wirksamkeit von Ramucirumab in Kombination mit Dacarbazin bei Patienten mit neuroendokrinen, fortgeschrittenen Tumoren der Bauchspeicheldrüse, welche eventuell schon Absiedlungen (Metastasen) gebildet haben.

Ongoing
2
45
Europe
Concentrate for solution for infusion, Cyramza 10 mg/ml
Martin-Luther-Universität Halle-Wittenberg, Lilly Deutschland GmbH
Progressive well-differentiated metastatic pancreatic neuroendocrine tumors Progrediente, gut differenzierte metastasierte pankreatische neuroendokrine Tumore, Progressive well-differentiated metastatic neuroendocrine tumors of the pancreas Neuroendokriner Tumor der Bauchspeicheldrüse, welcher fortgeschritten ist und eventuell schon Absiedlungen (Metastasen) gebildet hat, Diseases [C] - Cancer [C04]
 
 
NU 16H08, NCT03226249: PET-Directed Therapy With Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Classical Hodgkin Lymphoma

Active, not recruiting
2
30
US
Computed Tomography, CAT, CAT Scan, Computerized Axial Tomography, computerized tomography, CT, CT SCAN, tomography, Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Fludeoxyglucose F-18, 18FDG, FDG, fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Laboratory Biomarker Analysis, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, Vinblastine Sulfate, 29060 LE, 29060-LE, Exal, Velban, Velbe, Velsar, VINCALEUKOBLASTINE
Northwestern University, National Cancer Institute (NCI), Merck Sharp & Dohme LLC
Classical Hodgkin Lymphoma, Lymphocyte-Depleted Classical Hodgkin Lymphoma, Lymphocyte-Rich Classical Hodgkin Lymphoma, Mixed Cellularity Classical Hodgkin Lymphoma, Nodular Sclerosis Classical Hodgkin Lymphoma
05/19
10/24
NCT02758717: Nivolumab and Brentuximab Vedotin in Treating Older Patients With Untreated Hodgkin Lymphoma

Checkmark From trial in combination with Opdivo for hodgkin lymphoma at ASH 2019
Dec 2019 - Dec 2019: From trial in combination with Opdivo for hodgkin lymphoma at ASH 2019
Checkmark Presentation of data in combination with Opdivo for 1L Hodgkin lymphoma at ASH 2019
Dec 2019 - Dec 2019: Presentation of data in combination with Opdivo for 1L Hodgkin lymphoma at ASH 2019
Active, not recruiting
2
46
US
Brentuximab Vedotin, ADC SGN-35, Adcetris, Anti-CD30 Antibody-Drug Conjugate SGN-35, Anti-CD30 Monoclonal Antibody-MMAE SGN-35, Anti-CD30 Monoclonal Antibody-Monomethylauristatin E SGN-35, cAC10-vcMMAE, SGN-35, Nivolumab, BMS-936558, MDX-1106, NIVO, ONO-4538, Opdivo
Academic and Community Cancer Research United, National Cancer Institute (NCI)
Ann Arbor Stage IB Hodgkin Lymphoma, Ann Arbor Stage II Hodgkin Lymphoma, Ann Arbor Stage IIA Hodgkin Lymphoma, Ann Arbor Stage IIB Hodgkin Lymphoma, Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage IIIA Hodgkin Lymphoma, Ann Arbor Stage IIIB Hodgkin Lymphoma, Ann Arbor Stage IV Hodgkin Lymphoma, Ann Arbor Stage IVA Hodgkin Lymphoma, Ann Arbor Stage IVB Hodgkin Lymphoma, Classic Hodgkin Lymphoma
08/19
05/24
2017-003556-23: Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy (PROMIT) Präkonditionierung von Tumor, Tumormikromilieu und Immunsysten für Immuntherapie

Not yet recruiting
2
38
Europe
Opdivo, Yervoy, Pembrolizumab, Powder and solvent for solution for infusion, Concentrate for solution for infusion, Detimedac, Opdivo, Yervoy, Keytruda
University Hospital of the Friedrich-Alexander University Erlangen-Nürnberg, Deutsche Krebshilfe, University Hospital of the Friedrich-Alexander University Erlangen-Nürnberg
Melanoma, Skin cancer, Diseases [C] - Cancer [C04]
 
 
IMCgp100-202, NCT03070392 / 2015-003153-18: Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma

Active, not recruiting
2
378
Europe, Canada, US, RoW
IMCgp100, Dacarbazine, DTIC-Dome, DTIC, DIC, Imidazole Carboxamide, Ipilimumab, Yervoy, Pembrolizumab, Keytruda
Immunocore Ltd
Uveal Melanoma
10/20
06/25
NCT01920932: Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphoma

Active, not recruiting
2
77
US
brentuximab vedotin, SGN-35, Adcetris(R), etoposide, VP-16, Vepesid(R), prednisone, prednisolone, doxorubicin, Adriamycin(R), cyclophosphamide, Cytoxan(R), Dacarbazine(R), Dimethyl Triazeno Imidazole Carboximide (DTIC), filgrastim, Neupogen(R), quality of life assessment, radiation therapy, irradiation, radiotherapy, radiation
St. Jude Children's Research Hospital, Seagen Inc.
Stage II Childhood Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage IV Childhood Hodgkin Lymphoma
11/20
05/28
AMC-085, NCT02298257: A Pilot Trial of AVD and Brentuximab Vedotin (SGN-35) in the Treatment of Stage III-IV HIV-associated Hodgkin Lymphoma

Completed
2
9
Europe
brentuximab vedotin, adcetris, SGN-35, anti-CD30 ADC SGN-35, anti-CD30 antibody-drug conjugate SGN-35, antibody-drug conjugate SGN-35, Doxorubicin Hydrochloride, Vinblastine, Velban, Velsar, VLB, Dacarbazine
The Lymphoma Academic Research Organisation
HIV Infection, HIV-associated Hodgkin Lymphoma, Stage III Adult Hodgkin Lymphoma, Stage IV Adult Hodgkin Lymphoma
12/21
08/22
NCT02501551: Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

Recruiting
2
36
RoW
regorafenib
Yonsei University
Melanoma
05/22
06/22
ACCRU-LY-1601, NCT03233347: Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin Lymphoma

Active, not recruiting
2
82
US
Brentuximab Vedotin, ADC SGN-35, Adcetris, Anti-CD30 Antibody-Drug Conjugate SGN-35, Anti-CD30 Monoclonal Antibody-MMAE SGN-35, Anti-CD30 Monoclonal Antibody-Monomethylauristatin E SGN-35, cAC10-vcMMAE, SGN-35, Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Laboratory Biomarker Analysis, Nivolumab, BMS-936558, MDX-1106, NIVO, ONO-4538, Opdivo, Vinblastine, Vincaleucoblastine, VLB
Academic and Community Cancer Research United, National Cancer Institute (NCI)
Ann Arbor Stage I Hodgkin Lymphoma, Ann Arbor Stage IA Hodgkin Lymphoma, Ann Arbor Stage IB Hodgkin Lymphoma, Ann Arbor Stage II Hodgkin Lymphoma, Ann Arbor Stage IIA Hodgkin Lymphoma, Ann Arbor Stage IIB Hodgkin Lymphoma, Classic Hodgkin Lymphoma
07/22
07/25
NCT06201507: BV-AVD-R Treatment Children Hodgkin's Lymphoma

Enrolling by invitation
2
44
RoW
Brentuximab vedotin, Adcetris, Rituximab, Rituxan, Doxorubicin, Doxil, Adriamycin, Vincristine, Oncovin, Dacarbazine, DTIC
Beijing Children's Hospital
Hodgkin Lymphoma
12/24
12/25
SGN35-027, NCT03646123 / 2020-004027-17: Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma

Checkmark Part B and Part C data from SGN35-027 study in combination with Opdivo for classical Hodgkin Lymphoma at ASH 2022
Dec 2022 - Dec 2022: Part B and Part C data from SGN35-027 study in combination with Opdivo for classical Hodgkin Lymphoma at ASH 2022
Active, not recruiting
2
255
Europe, US, RoW
brentuximab vedotin, Adcetris, SGN-35, doxorubicin, vinblastine, dacarbazine, G-CSF, filgrastim, pegfilgrastim, nivolumab, Opdivo
Seagen Inc., Bristol-Myers Squibb
Hodgkin Lymphoma
11/22
06/26
NCT04200040: A Clinical Study to Evaluate the Safety and Efficacy of OrienX010 in Unresectable Malignant Melanoma Patients

Recruiting
2
165
RoW
OrienX010 injection, Recombinant Human GM-CSF Herpes Simplex Virus Injection, Dacarbazine (DTIC)
OrienGene Biotechnology Ltd.
Melanoma (Skin)
12/22
12/22
SGN35-015, NCT01716806 / 2019-003982-17: A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)

Checkmark Additional data for front-line Hodgkin's lymphoma in elderly patients (ASH 2014)
Nov 2014 - Nov 2014: Additional data for front-line Hodgkin's lymphoma in elderly patients (ASH 2014)
Checkmark For newly diagnosed Hodgkin's lymphoma in elderly patients
Dec 2013 - Dec 2013: For newly diagnosed Hodgkin's lymphoma in elderly patients
Checkmark Elderly chemo-intolerant Hodgkin's lymphoma patients
More
Completed
2
131
Canada, US
brentuximab vedotin, Adcetris; SGN-35, bendamustine, dacarbazine, nivolumab
Seagen Inc., Bristol-Myers Squibb
Hodgkin Disease, Peripheral T Cell Lymphoma
04/23
09/23
NCT04843267: A Multi-center, Non-randomized, Open-label Phase II Clinical Study on the Treatment of Newly Diagnosed Advanced Hodgkin's Lymphoma With PD-1 Antibody (Tislelizumab) Combined With AVD Regimen (Doxorubicin, Vindesine, Dacarbazine) Under the Guidance of PET/CT

Recruiting
2
30
RoW
Tislelizumab
Sun Yat-sen University
Hodgkin Lymphoma, Chemotherapy Effect
05/23
05/25
PROMIT, NCT04225390: Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy

Recruiting
2
38
Europe
Dacarbazine (DTIC), DTIC
University of Erlangen-Nürnberg Medical School, University Hospital Regensburg, Wuerzburg University Hospital
Immunotherapy
06/23
07/23
COBRA, NCT03517137 / 2017-000498-35: Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study

Active, not recruiting
2
150
Europe
Brentuximab Vedotin, Adriamycin, Vinblastine, Dacarbazine, Etoposide, Cyclophosphamide, Radiation Therapy
European Organisation for Research and Treatment of Cancer - EORTC
Advanced Hodgkin Lymphoma
08/23
11/26
KEYNOTE-C11, NCT05008224 / 2021-001244-95: Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/)

Checkmark Presentation of data from KEYNOTE-C11 trial for 1L Classic Hodgkin Lymphoma at ASH 2022
Nov 2022 - Nov 2022: Presentation of data from KEYNOTE-C11 trial for 1L Classic Hodgkin Lymphoma at ASH 2022
Active, not recruiting
2
146
Europe, Canada, US, RoW
Pembrolizumab, MK-3475, SCH 900475, KEYTRUDA®, Doxorubicin, Adriamycin, DOXIL®, Rubex®, Vinblastine, Alkaban-AQ®, Velban®, Dacarbazine, Dtic-Dome®, Bleomycin, Blenoxane®, Etoposide, Toposar®, VePesid®, Etopophos®, VP-16, Etoposide phosphate, Cyclophosphamide, Neosar®, Cytoxan®, Vincristine, Oncovin®, Vincasar PFS®, Procarbazine, Matulane®, Prednisone, Liquid Pred®, Meticorten®, Orasone®, Deltasone®
Merck Sharp & Dohme LLC, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co.,Inc
Classical Hodgkin Lymphoma
10/23
05/24
NIVAHL, NCT03004833 / 2016-002626-37: Nivolumab and AVD in Early-stage Unfavorable Classical Hodgkin Lymphoma

Active, not recruiting
2
110
Europe
Nivolumab, Adriamycin, Vinblastine, Dacarbazine
University of Cologne
Classical Hodgkin Lymphoma
12/23
12/23
NCT04067037: Camrelizumab Combined With AVD in the First-line Treatment for Patients With Advanced Classical Hodgkin's Lymphoma

Recruiting
2
60
RoW
Camrelizumab, SHR-1210, Epirubicin, Epirubicin hydrochloride, Vincristine, Oncovin, Dacarbazine
Henan Cancer Hospital
Classical Hodgkin Lymphoma
06/24
12/24
FLASH, NCT04733183: Efficacy and Safety of L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcoma

Recruiting
2
98
Europe
Dacarbazine, DTIC, onfekafusp alfa, L19TNF
Philogen S.p.A.
Soft Tissue Sarcoma
12/24
12/24
NCT04727242: CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma

Recruiting
2
25
US
Gemcitabine, Gemzar, Infugem, difluorodeoxycytidine hydrochloride, Dacarbazine, Dimethyl (triazeno) imidazolecarboxamide, Dacarbazine - DTIC, Biocarbazine, Cytoreductive Surgery, Functional Assessment of Cancer Therapy (FACT) G questionnaire, Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) Scan, Gadolinium
Kristen Ganjoo
LMS - Leiomyosarcoma, Uterine Leiomyosarcoma
01/25
01/25
NCT03712202: Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin Lymphoma

Active, not recruiting
2
155
US
Bleomycin, BLEO, BLM, Brentuximab Vedotin, ADC SGN-35, Adcetris, Anti-CD30 Antibody-Drug Conjugate SGN-35, Anti-CD30 Monoclonal Antibody-MMAE SGN-35, Anti-CD30 Monoclonal Antibody-Monomethylauristatin E SGN-35, cAC10-vcMMAE, SGN-35, Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Nivolumab, BMS-936558, MDX-1106, NIVO, ONO-4538, Opdivo, Quality-of-Life Assessment, Quality of Life Assessment, Vinblastine, Vincaleucoblastine, VLB
City of Hope Medical Center, National Cancer Institute (NCI)
Ann Arbor Stage I Hodgkin Lymphoma, Ann Arbor Stage I Mixed Cellularity Classic Hodgkin Lymphoma, Ann Arbor Stage I Nodular Sclerosis Classic Hodgkin Lymphoma, Ann Arbor Stage IA Hodgkin Lymphoma, Ann Arbor Stage IB Hodgkin Lymphoma, Ann Arbor Stage II Hodgkin Lymphoma, Ann Arbor Stage IIA Hodgkin Lymphoma, Ann Arbor Stage IIB Hodgkin Lymphoma, Classic Hodgkin Lymphoma, Lymphocyte-Rich Classic Hodgkin Lymphoma, Ann Arbor Stage I Lymphocyte-Depleted Classic HL, Ann Arbor Stage II Lymphocyte-Depleted Classic HL, Ann Arbor Stage II Mixed Cellularity Classic HL, Ann Arbor Stage II Nodular Sclerosis Classic HL
09/24
09/24
STRADA, NCT03023124 / 2016-004051-78: Study With Trabectedin Versus Adriamycin Plus Dacarbazine, in Patients With Advanced Solitary Fibrous Tumor

Active, not recruiting
2
23
Europe
Trabectedin, Adriamycin, Dacarbazine
Italian Sarcoma Group
Solitary Fibrous Tumors
12/24
12/24
NCT06164275: Pembrolizumab Followed by Chemotherapy for the Treatment of Patients With Classical Hodgkin Lymphoma

Recruiting
2
30
US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, CT, CT Scan, tomography, Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, MUGA, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Pembrolizumab, BCD-201, Keytruda, Lambrolizumab, MK-3475, Pembrolizumab Biosimilar BCD-201, SCH 900475, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Vinblastine, Vincaleucoblastine, VLB
Northwestern University, National Cancer Institute (NCI)
Classic Hodgkin Lymphoma
12/29
12/31
NCI-2017-01718, NCT03331341: Doxorubicin Hydrochloride, Pembrolizumab, Vinblastine, and Dacarbazine in Treating Patients With Classical Hodgkin Lymphoma

Active, not recruiting
2
50
US
Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Laboratory Biomarker Analysis, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Vinblastine, Vincaleucoblastine, VLB
University of Washington
Classical Hodgkin Lymphoma
12/23
07/29
NCT06377566: A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Recruiting
2
71
US
Brentuximab vedotin, Doxorubicin, Vinblastine, Dacarbazine, Pembrolizumab, Gemcitabine, Vinorelbine, FDG-PET/CT scan
Memorial Sloan Kettering Cancer Center, Seagen Inc.
Hodgkin Lymphoma
04/27
04/27
NCT05466474: PD-1 Antibody Tislelizumab Combined With Dacarbazine in the Treatment of Advanced Melanoma

Recruiting
2
40
RoW
Tislelizumab Injection, Dacarbazine
Henan Cancer Hospital
Advanced Melanoma
04/24
04/24
TAGGED, NCT04535271: Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Leiomyosarcoma

Recruiting
2
80
US
Trabectedin, Gemcitabine, Dacarbazine
Sarcoma Oncology Research Center, LLC
Leiomyosarcoma
09/24
12/24
NCT05900765: A Study of Zimberelimab(GLS-010) Combined With AVD for Newly Diagnosed Early-stage Hodgkin's Lymphoma

Recruiting
2
54
RoW
Zimberelimab 240mg, GLS-010
Sun Yat-sen University, Guangzhou Gloria Biosciences Co., Ltd.
Classical Hodgkin Lymphoma
06/25
06/26
DTIC, NCT00553618: Adjuvant, Combined Interleukin 2 (Proleukin) and (Dacarbazine) in High-risk Melanoma Patients

Active, not recruiting
2
160
US
Proleukin and Dacarbazine, Proleukin, Dacarbazine
University of Louisville, James Graham Brown Cancer Center
Metastatic Melanoma
08/25
08/26
NCT05922904: PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Recruiting
2
50
US
Brentuximab vedotin, Doxorubicin Hydrochloride, Adriamycin PFS®, Adriamycin RDF™, Adriamycin®, Rubex®, Pembrolizumab, SGN-35, Adcetris, Dacarbazine, DTIC-Dome®
M.D. Anderson Cancer Center, Merck Sharp & Dohme LLC, Seagen Inc.
Hodgkin Lymphoma
10/25
10/25
NCT03755804: Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Recruiting
2
250
US
bendamustine, TREANDA (R), Etoposide, VP-16, Vepeside, Doxorubicin, Adriamycin (R), Bleomycin, Blenoxane (R), Vincristine, Oncovin (R), Vinblastine, Velban (R), Prednisone, Prednisolone, Filgrastim, Neupogen (R), Brentuximab Vedotin, Adcetris, Cyclophosphamide, Cytoxan (R), DTIC, DACARBAZINE (R), Dimethyl Triazeno Imidazole Carboximide, Quality of Life Measurements, Quality of Life Measurements (QOL), Radiotherapy, radiation therapy, irradiation
St. Jude Children's Research Hospital, Teva Pharmaceuticals USA, Seagen Inc.
Hodgkin Lymphoma
01/27
07/28
KEYNOTE-667, NCT03407144 / 2017-001123-53: Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/)

Active, not recruiting
2
340
Europe, US, RoW
pembrolizumab, MK-3475, doxorubicin, vinblastine, dacarbazine, cyclophosphamide, vincristine, prednisone/prednisolone, bleomycin, etoposide, Etoposide Phosphate, Radiotherapy (RT)
Merck Sharp & Dohme LLC
Hodgkin Lymphoma
02/27
02/27
NCT05404945: Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and Above

Recruiting
2
44
US
Pembrolizumab, Doxorubicin, Adriamycin, Vinblastine, Dacarbazine, Brentuximab vedotin
University of Virginia, Merck Sharp & Dohme LLC
Classical Hodgkin Lymphoma
10/27
10/27
2005-001161-34: Phase I-II multicenter, randomized, open-label, clinical and pharmacokinetic study of plitidepsin, administered alone or in combination with dacarbazine, as front-line therapy to subjects with unresectable advanced melanoma

Ongoing
1/2
30
Europe
plitidepsin (Aplidin), DTIC-DOME, APL, DTIC-DOME, DTIC-DOME
Pharma Mar SA, Pharma Mar SA, sociedad unipersonal
unresectable advanced melanoma
 
 
NCT02076646: A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

Active, not recruiting
1/2
96
Europe
L19IL2 - Ph I, L19IL2 at RD - Ph II, DTIC, DETICENE®
Philogen S.p.A.
Metastatic Melanoma Stage IV
05/16
06/22
C25004, NCT02979522 / 2015-004112-38: A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin Lymphoma

Active, not recruiting
1/2
59
Europe, Japan, US, RoW
Brentuximab vedotin, Adcetris, Doxorubicin, Adriamycin, Vinblastine, Dacarbazine
Takeda
Hodgkin Disease
05/20
09/29
NCT01771107: Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma

Active, not recruiting
1/2
41
Europe, US
Brentuximab Vedotin, ADC SGN-35, Adcetris, Anti-CD30 Antibody-Drug Conjugate SGN-35, Anti-CD30 Monoclonal Antibody-MMAE SGN-35, Anti-CD30 Monoclonal Antibody-Monomethylauristatin E SGN-35, cAC10-vcMMAE, SGN-35, Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin HCl, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Pharmacological Study, Vinblastine, Vincaleucoblastine, VLB
National Cancer Institute (NCI), The Lymphoma Academic Research Organisation
AIDS-Related Hodgkin Lymphoma, Ann Arbor Stage II Hodgkin Lymphoma, Ann Arbor Stage IIA Hodgkin Lymphoma, Ann Arbor Stage IIB Hodgkin Lymphoma, Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage IIIA Hodgkin Lymphoma, Ann Arbor Stage IIIB Hodgkin Lymphoma, Ann Arbor Stage IV Hodgkin Lymphoma, Ann Arbor Stage IVA Hodgkin Lymphoma, Ann Arbor Stage IVB Hodgkin Lymphoma, Classic Hodgkin Lymphoma, HIV Infection
10/21
02/25
ImmunoSarc, NCT03277924 / 2016-004040-10: Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Recruiting
1/2
270
Europe
Sunitinib 37.5 MG, Sunitinib 25 MG [Sutent], Sutent, Nivolumab 100 MG/10 ML [Opdivo], Opdivo, Epirubicin, Ifosfamide, Doxorubicin, Dacarbazine, Cisplatin, Methotrexate
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma, Bone Sarcoma
06/25
06/25
NCT02994498: Safety and Efficacy of DCB-BO1301 in Advanced Melanoma

Not yet recruiting
1/2
33
NA
DCB-BO1301
Chung Mei Biopharma Co., Ltd
Advanced Melanoma
09/25
12/25
NCT03033914: A(B)VD Followed by Nivolumab as Frontline Therapy for Higher Risk Patients With Classical Hodgkin Lymphoma (HL)

Recruiting
1/2
81
Canada, US
doxorubicin, Bleomycin, vinblastine, dacarbazine, Nivolumab
Memorial Sloan Kettering Cancer Center, Bristol-Myers Squibb, Barbara Ann Karmanos Cancer Institute, British Columbia Cancer Agency
Hodgkin Lymphoma
01/26
01/26

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