Neoplasms, Connective and Soft Tissue  >>  melphalan  >>  Phase 1
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6 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
melphalan / Generic mfg.
NCT00001577: Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

Completed
1
30
US
double isolated limb perfusion with melphalan alone
National Cancer Institute (NCI)
Melanoma, Sarcoma
 
03/00
NCT00003081: Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma

Completed
1
16
US
filgrastim, busulfan, melphalan, thiotepa, peripheral blood stem cell transplantation, radiation therapy
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Sarcoma
01/02
01/02
NCT00003926: Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Terminated
1
13
US
amifostine trihydrate, Ethyol, busulfan, Busulfex, filgrastim, granulocyte colony-stimulating factor, G-CSF, melphalan, Alkeran, thiotepa, Thioplex, peripheral blood stem cell transplantation (PBSC), bone marrow transplant
Masonic Cancer Center, University of Minnesota
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Chordoma, Kidney Cancer, Liver Cancer, Neuroblastoma, Ovarian Cancer, Retinoblastoma, Sarcoma
08/02
08/03
NCT00112645: Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumors

Completed
1
10
US
anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methotrexate, methylprednisolone, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation, umbilical cord blood transplantation
Milton S. Hershey Medical Center
Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
04/10
02/11
NCT00623077: MT2004-30: Tomotherapy for Solid Tumors

Terminated
1
23
US
filgrastim, G-CSF, Sargramostim, busulfan, Busulfex, Myleran, etoposide, Eposin, VP-16, ifosfamide, Mitoxana, Ifex, melphalan, Alkeran, thiotepa, stem cell transplantation, HPC infusion, tomotherapy, total marrow irradiation, Mesna, Uromitexan®, Mesnex, Whole lung radiation
Masonic Cancer Center, University of Minnesota
Brain and Central Nervous System Tumors, Kidney Cancer, Liver Cancer, Retinoblastoma, Sarcoma
07/12
10/16
NCT01969942: A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma

Withdrawn
1
0
US
allogeneic stem cell transplantation, Clyclophosphamide, Fludarabina, Busulfan, Melphalan
University of Louisville
Ewing Sarcoma
10/16
10/16

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