abiraterone acetate / Generic mfg.  >>  Phase 2
Welcome,         Profile    Billing    Logout  

147 Trials

   Remove Filter

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
abiraterone acetate / Generic mfg.
2008-002210-22: An Extended Study of CB7630 (Abiraterone Acetate) in Patients with Advanced Prostate Cancer Who Have Failed Androgen Deprivation and Docetaxel-Based Chemotherapy and Completed Clinical Study COU-AA-003

Ongoing
2
20
Europe
abiraterone acetate, Abiraterone Acetate, CB7630, Capsule, hard, Tablet
Janssen Oncology, Inc., Janssen Oncology, Inc.
Hormone refractory prostate cancer
 
 
2013-000674-30: Multicenter clinical trial, randomized phase II "window of opportunity" which aims to test the biological activity of abiraterone acetate administered as neoadjuvant therapy in patients with prostate cancer at high risk. (multicenter study).

Ongoing
2
62
Europe
ZYTIGA, Tablet, ZYTIGA
AOU SAN LUIGI GONZAGA - SCDU ONCOLOGIA MEDICA, JANSSEN CILAG
PROSTATE CANCER PATIENTS WITH HIGH RISK, PROSTATE CANCER PATIENTS WITH HIGH RISK, Diseases [C] - Cancer [C04]
 
 
NCT01508234: Pharmacodynamic Study of Abiraterone in the Treatment of Advanced Prostate Cancer

Not yet recruiting
2
30
US
Abiraterone acetate plus prednisone, ZYTIGA
University of Washington, Janssen, LP
Prostatic Neoplasm, Prostate Cancer, Prostatic Adenocarcinoma, Hormone Refractory Prostate Cancer, Stage IV Prostate Carcinoma
10/13
 
IMAAGEN, NCT01314118: Impact of Abiraterone Acetate in Prostate-Specific Antigen

Checkmark ASCO 2015
May 2015 - May 2015: ASCO 2015
Active, not recruiting
2
131
US
abiraterone acetate in combination with prednisone
Janssen Biotech, Inc.
Prostate Cancer, Prostatic Neoplasm
12/13
07/25
2014-001274-34: Phase II trial of abiraterone acetate in patients with relapsed and/or metastatic, castration resistant, salivary gland cancers. Studio di fase II con abiraterone acetato nel paziente con tumore ricorrente/metastatico delle ghiandole salivari resistente al blocco ormonale completo.

Ongoing
2
24
Europe
Abiraterone Acetato, Tablet, Zytiga
Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Janssen-Cilag SpA
relapsed and/or metastatic, castration resistant, salivary gland cancer tumore delle ghiandole salivari resistente alla castrazione, ricorrente e/o metastatico, relapsed and/or metastatic, castration resistant, salivary gland cancer tumore delle ghiandole salivari resistente alla castrazione, ricorrente e/o metastatico, Diseases [C] - Cancer [C04]
 
 
2014-001128-31: Phase II single-arm study evaluating abiraterone acetate (plus prednisolone) and Gonadotropin-Releasing Hormone (GnRH) agonist prior to receiving radical radiotherapy in high risk localised prostate carcinoma patients

Ongoing
2
36
Europe
abiraterone acetate, Tablet, Zytiga
Irish Clinical Oncology Research Group CLG, trading as Cancer Trials Ireland, Janssen Pharmaceutica NV
High-risk prostate cancer, Prostate cancer with a high risk of progressive disease, Diseases [C] - Cancer [C04]
 
 
2014-002071-29: STUDY WITH RADIOTHERAPY TREATMENT WITH ANDROGEN DEPRIVATION THERAPY (ADT) WITH OR WITHOUT ABIRATERONE ACETATE AND PREDNISONE IN CRPC STUDIO CON RADIOTERAPIA E TERAPIA DI DEPRIVAZIONE ANDROGENICA CON O SENZA ABIRATERONE ACETATO PIù PREDNISONE IN CRPC

Ongoing
2
172
Europe
Abiraterone acetato, PREDNISONE, BICALUTAMIDE, Tablet, zytiga, deltacortene, CASODEX
DIPARTIMENTO DI ONCOLOGIA MEDICA USL8, janssen cilag international, ITT
LOCALLY ADVANCED VERY HIGH-RISK PROSTATE CANCER CARCINOMA PROSTATICO LOCALMENTE AVANZATO AD ALTO RISCHIO, PROSTATE CANCER TUMORE ALLA PRSTATA, Diseases [C] - Cancer [C04]
 
 
2014-004513-90: Is monitoring of plasmalevels of abiraterone a possible predictor for the response to Abiraterone treatment, in patients with metastatic prostate cancer? Is de bloedconcentratie van abirateron van voorspellende waarde voor het effect van dit geneesmiddel in patiënten met uitgezaaid prostaatkanker?

Ongoing
2
50
Europe
Tablet, Zytiga
Radboud UMC, Janssen BV
Metastatic Castration Resistant Prostate Cancer (mCRPC), Metastatic Prostate Cancer, Diseases [C] - Cancer [C04]
 
 
2013-000293-29: Abiraterone treatment for patients with relapsed ovarian cancer.

Ongoing
2
47
Europe
Abiraterone acetate, Zytiga, Zytiga
The Royal Marsden NHS Foundation Trust, The Institute of Cancer Research, Janssen-Cilag Ltd.
Epithelial ovarian cancer (including fallopian tube and primary peritoneal)
 
 
NCT01309672: S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy

Checkmark ASCO-GU 2015
Feb 2015 - Feb 2015: ASCO-GU 2015
Active, not recruiting
2
41
US
abiraterone acetate, Prednisone
SWOG Cancer Research Network, National Cancer Institute (NCI)
Prostate Cancer
11/16
10/24
2016-004963-38: Optimal patients with Metastasized Hormone Resistant Prostate Cancer Previously Treated with Docetaxel Optimale behandeling voor patienten met een uitgezaaide hormoonongevoelige prostaatkanker die eerder zijn behandeld met docetaxel.

Ongoing
2
152
Europe
Cabazitaxel/ Jevtana, Xtandi (enzalutamide), Zytiga (abiraterone acetate), XRP6258, Concentrate and solvent for concentrate for solution for infusion, Capsule, soft, Tablet, Jevtana (cabazitaxel), Xtandi (enzalutamide) 40mg soft capsules, Zytiga
Netherlands Cancer Institute, Sanofi Genzyme
Metastasized Castration Resistant Prostate Cancer Gemetastaseerd Castratieresistent Prostaat carcinoom, Prostate cancer Prostaatkanker, Diseases [C] - Cancer [C04]
 
 
NCT01972217 / 2013-003520-37: Ph II Study to Evaluate Olaparib With Abiraterone in Treating Metastatic Castration Resistant Prostate Cancer.

Checkmark For P2 trial in mCRPC
Jun 2020 - Jun 2020: For P2 trial in mCRPC
Checkmark Study 08 data in combination with abiraterone in mCRPC at ASCO 2018
Jun 2018 - Jun 2018: Study 08 data in combination with abiraterone in mCRPC at ASCO 2018
Checkmark Completion of enrollment in P2 trial for metastatic castration resistant prostate cancer
More
Completed
2
158
Europe, Canada, US, RoW
Olaparib, PARP inhibition, Placebo, Placebo to PARP inhibition, Abiraterone, Prednisone or prednisolone
AstraZeneca, Merck Sharp & Dohme LLC
Metastatic Castration-resistant Prostate Cancer
09/17
08/23
NCT02117531: A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of VT-464 in Patients With Metastatic Castration Resistant Prostate Cancer Who Have Previously Been Treated With Enzalutamide

Recruiting
2
52
US
VT-464
National Cancer Institute (NCI)
Prostate Cancer, Prostatic Neoplasms, Neoplasms, Prostate
03/19
03/19
Talapro-1, NCT03148795 / 2016-002036-32: A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer

Checkmark Additional data for metastatic castration-resistant 2L prostate cancer from TALAPRO-1 study
Aug 2021 - Aug 2021: Additional data for metastatic castration-resistant 2L prostate cancer from TALAPRO-1 study
Checkmark From TALAPRO-1 study for heavily pretreated mCRPC
Apr 2021 - Apr 2021: From TALAPRO-1 study for heavily pretreated mCRPC
Checkmark From TALAPRO-1 trial for mCRPC at ASCO 2020
More
Completed
2
128
Europe, US, RoW
Talazoparib, MDV3800
Pfizer, Medivation, Inc.
Prostate Cancer
09/20
03/23
NCT04356430: Neoadjuvant Therapy of Abiraterone Plus ADT for High Risk Prostate Cancer

Active, not recruiting
2
75
RoW
Abiraterone Acetate, Prednisone, Goserelin 10.8 mg
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Prostate Cancer
03/21
12/23
NCI-2019-03812, NCT03999515: Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer

Terminated
2
3
US
Abiraterone Acetate, 154229-18-2, 17-(3-Pyridyl)-5, 16-androstadien-3beta-acetate, Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, acetate (ester), CB7630, Yonsa, Zytiga, BR9004, BR9004-1, JNJ-212082, Enzalutamide, 915087-33-1, ASP9785, Benzamide, MDV3100, Xtandi, Erdafitinib, Balversa, JNJ-42756493
University of Washington, Janssen Research & Development, LLC
Castration-Resistant Prostate Carcinoma, Double-Negative Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
06/21
06/21
NCT04102124: A Study of SHR3680 in Combination With SHR3162 in the Treatment of mCRPC

Active, not recruiting
2
144
RoW
SHR3680, SHR3162, SHR3680(Placebo), SHR3162(Placebo)
Jiangsu HengRui Medicine Co., Ltd.
Prostate Cancer, Castration-resistant Prostate Cancer
11/21
11/22
NCT03565835: Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer

Active, not recruiting
2
32
US
Abiraterone Acetate, Prednisone
Montefiore Medical Center
Prostatic Neoplasms
11/21
01/23
NCT02025010: Study of Abiraterone Acetate Without Exogenous Glucocorticoids in Men With Castration-resistant Prostate Cancer

Active, not recruiting
2
60
US
abiraterone acetate, JNJ21208
Dana-Farber Cancer Institute, Janssen Research & Development, LLC
Castration-resistant Prostate Cancer
12/21
09/24
CABA-V7, NCT03050866: Cabazitaxel in mCRPC Patients With AR-V7 Positive Circulating Tumor Cells (CTCs)

Active, not recruiting
2
140
Europe
Cabazitaxel, Jevtana, Antihistamine, Corticosteroid, H2 antagonist, histamine H2 receptors blockers, Antiemetic
Erasmus Medical Center, Sanofi
Circulating Tumor Cell, Metastatic Prostate Cancer
01/22
08/22
NCT03899467: The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC

Completed
2
61
US
GT0918, proxalutamide, androgen receptor antagonist
Suzhou Kintor Pharmaceutical Inc,
Metastatic Castrate Resistant Prostate Cancer (mCRPC), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
03/22
09/22
2019-004817-15: A prospective, biomarker-based, clinical trial in patients with metastatic castration resistant prostate cancer

Not yet recruiting
2
150
Europe
cabazitaxel, Docetaxel Zentiva, Xtandi, Concentrate and solvent for solution for infusion, Tablet, Capsule, Cabazitaxel Jevtana, Docetaxel zentiva, Zytiga, Xtandi
GZA vzw, Kom op tegen Kanker
Metastatic castration resistant prostate cancer, Metastatic castration resistant prostate cancer, Diseases [C] - Cancer [C04]
 
 
NCI-2018-01548, NCT03649841: Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

Terminated
2
10
US
Antiandrogen Therapy, ADT, Androgen Deprivation Therapy, Androgen Deprivation Therapy (ADT), Anti-androgen Therapy, Anti-androgen Treatment, Antiandrogen Treatment, Hormone Deprivation Therapy, Hormone-Deprivation Therapy, Abiraterone Acetate, 17-(3-Pyridyl)-5,16-androstadien-3beta-acetate, 154229-18-2, Yonsa, Zytiga, Prednisone, 10023, Delta 1-Cortisone, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, NOS, Radiotherapeutics, radiotherapy, RT, ENERGY TYPE
University of Washington, National Cancer Institute (NCI)
Castration-Sensitive Prostate Carcinoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Prostate Small Cell Neuroendocrine Carcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
09/22
02/23
NCT04158245: 18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies

Completed
2
10
US
18F-fluciclovine PET Scan, Axumin
Tulane University, Blue Earth Diagnostics
Metastatic Castration-resistant Prostate Cancer
09/22
04/23
NCT04603833: A Study of SHR3680 in Combination With Docetaxel in the Treatment of mCRPC

Recruiting
2
150
RoW
SHR3680+Docetaxel, SHR3680, Docetaxel
Jiangsu HengRui Medicine Co., Ltd.
Prostate Cancer Metastatic
10/22
12/22
NCT04736108: Neoadjuvant Therapy of Abiraterone Plus ADT for Intraductal Carcinoma of the Prostate

Not yet recruiting
2
50
RoW
Abiraterone acetate, Prednisolone, Goserelin
West China Hospital
Prostate Cancer
10/22
12/24
NCT03043807: A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy

Completed
2
26
US
Leuprolide Acetate, Lupron Deport, Docetaxel, Texotere, Bicalutamide, Casodex, Radiation, Abiraterone Acetate, Zytiga
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
10/22
10/22
COMBAT-CRPC, NCT03554317: COMbination of Bipolar Androgen Therapy and Nivolumab

Completed
2
45
US
Testosterone cypionate, Depot (DEPO)-Testosterone Injection, Nivolumab, BMS-936558, MDX1106, ONO-4538
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bristol-Myers Squibb
Castration-resistant Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer
10/22
01/23
PANTHER, NCT03098836: Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer

Active, not recruiting
2
93
US
ARN-509, apalutamide, Abiraterone Acetate, Zytiga, Prednisone
Daniel George, MD, Janssen Scientific Affairs, LLC
Prostate Cancer
02/25
02/25
NCT04869488: A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer

Active, not recruiting
2
93
RoW
Fluzoparib, Enzalutamide OR abiraterone acetate With Prednisone Acetate Tablets, Fluzoparib Combined With Apatinib
Jiangsu HengRui Medicine Co., Ltd.
Metastatic Castration Resistant Prostate Cancer
04/23
04/23
FAST Trial, NCT05223582: Fluzoparib and Abiraterone in the preSurgery Treatment of Prostate Cancer:

Active, not recruiting
2
34
RoW
Abiraterone acetate, Fluzoparib, Prednisone, Androgen deprivation therapy, Radical Prostatectomy
Fudan University
High-risk Prostate Cancer, Neoadjuvant Therapy
12/23
12/23
ChiCTR2100046198: Fluzoparib and Abiraterone in the preSurgery Treatment of Prostate Cancer

Completed
2
50
 
fluzoparib+abiraterone
Fudan University Shanghai Cancer Center; Fudan University Shanghai Cancer Center, Fudan University Shanghai Cancer Center
Prostate Caner
 
 
NCT02807805: Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer

Active, not recruiting
2
37
US
Abiraterone Acetate, CB7630, Zytiga, Niclosamide, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone
Mamta Parikh, National Cancer Institute (NCI)
Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
01/24
07/24
ARROW, NCT03939689: Study of I-131-1095 Radiotherapy in Combination With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer Who Are Chemotherapy Naive and Have Progressed on Abiraterone

Active, not recruiting
2
120
Canada, US
I-131-1095, Enzalutamide, Xtandi
Progenics Pharmaceuticals, Inc.
Metastatic Prostate Cancer, Castration-resistant Prostate Cancer, Prostatic Neoplasm, Cancer of the Prostate, Progressive mCRPC
09/23
09/24
2021-000943-30: A study to evaluate the switch from prednisone to dexamethasone in prostate cancer patients being treated with abiraterone Un estudio para evaluar el cambio de prednisona a dexametasona en pacientes con cáncer de próstata que están siendo tratados con abiraterona

Not yet recruiting
2
110
Europe
Dexamethasone, Tablet, Dexamethasone
SOGUG (Spanish Genitourinary Oncologic Group), SOGUG (Spanish Genitourinary Oncologic Group)
metastatic prostate cancer hormone sensitive cáncer de próstata metastásico hormonosensible, prostate cancer cáncer de próstata, Diseases [C] - Cancer [C04]
 
 
ChiCTR2200061437: Efficacy and safety of bipolar androgen therapy in mCRPC after progression on abiraterone or docetaxel: A prospective single-arm clinical study based on Chinese populations

Not yet recruiting
2
86
 
bipolar androgen therapy
West China Hospital of Sichuan University; West China Hospital of Sichuan University, West China Hospital of Sichuan University
Prostate Cancer
 
 
ChiCTR2100050150: A prospective, single-arm, small sample exploratory clinical study of fluzoparib combined with abiraterone in neoadjuvant treatment of oligometastatic hormone-sensitive prostate cancer

Not yet recruiting
2
30
 
Abiraterone combined with fluzoparib
Jiangsu Cancer Hospital; Jiangsu Cancer Hospital, Self-raised
Prostate cancer
 
 
NCT04207255: Addition of Opaganib to Androgen Antagonists in Patients With mCRPC

Completed
2
69
US
Opaganib, Abiraterone, Enzalutamide
Medical University of South Carolina, National Cancer Institute (NCI)
Prostate Cancer
08/23
07/24
NCT02903368: Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy

Active, not recruiting
2
118
US
Apalutamide, JNJ-56021927, ARN-509, Leuprolide, Lupron, Eligard, Prednisone, Deltasone, Abiraterone Acetate, Zytiga
Dana-Farber Cancer Institute, Janssen Scientific Affairs, LLC
Prostate Cancer
05/23
12/24
NCT03556904: FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE)

Completed
2
13
US
Ablative Radiation Therapy, Hormone therapy or chemotherapy, enzalutamide, abiraterone, docetaxel, cabazitaxel
University of Michigan Rogel Cancer Center
Prostate Cancer
07/23
07/23
NCT05376722: A Study of Pamiparib Combined With Abiraterone Acetate in Neoadjuvant Treatment of Prostate Cancer

Recruiting
2
30
RoW
pamiparib, abiraterone, prednisone
Hongqian Guo, First Affiliated Hospital of Zhejiang University, The First Affiliated Hospital of Soochow University, Nanjing First Hospital, Nanjing Medical University
Neoadjuvant Therapy
09/23
09/24
NCT05156450: TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer

Not yet recruiting
2
30
RoW
TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone
West China Hospital
Prostatic Neoplasms, Castration-Resistant, Drug Therapy, Combination
10/23
01/24
NCT02218606: Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer

Completed
2
80
US
Abiraterone acetate 1000 mg po daily, Cabazitaxel 25 mg/m2 IV, prednisone 5 mg po BID
Memorial Sloan Kettering Cancer Center, Sanofi, Thomas Jefferson University, Weill Medical College of Cornell University
Prostate Cancer
10/23
10/23
NCT03414034: Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer

Checkmark In combination with Zytiga in mCRPC at EMUC 2019
Nov 2019 - Nov 2019: In combination with Zytiga in mCRPC at EMUC 2019
Checkmark In combination with Zytiga in patients with mCRPC
Feb 2019 - Feb 2019: In combination with Zytiga in patients with mCRPC
Completed
2
72
US
Onvansertib, PCM-075, Abiraterone, Prednisone
Cardiff Oncology
Metastatic Castration-Resistant Prostate Cancer
10/23
10/23
NCT06173362: Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

Recruiting
2
75
US
Abiraterone, CB 7598, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Darolutamide, Antiandrogen ODM-201, BAY 1841788, BAY-1841788, BAY1841788, Nubeqa, ODM 201, ODM-201, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
Mamta Parikh, National Cancer Institute (NCI)
Advanced Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
11/26
05/27
RASTOM, NCT06134271: Rezvilutamide Plus Abiraterone for Metastatic Hormone-sensitive Prostate Cancer

Not yet recruiting
2
160
NA
Rezvilutamide, Rezvilutamide plus abiraterone, Continue previous treatment
Jianbin Bi
Metastatic Hormone-Sensitive Prostate Cancer
04/25
04/26
NCT04734730: Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

Recruiting
2
70
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Bicalutamide, Casodex, Cosudex, ICI 176,334, ICI 176334, Degarelix, FE200486, Firmagon, Goserelin Acetate, ZDX, Zoladex, Leuprolide Acetate, A-43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Lutrate, Procren, Procrin, Prostap, TAP-144, Trenantone, Uno-Enantone, Viadur, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Questionnaire Administration, Talazoparib, BMN 673, BMN-673
City of Hope Medical Center, National Cancer Institute (NCI)
Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
08/27
08/27
NCT01254864: Maximal Androgen Depletion Followed by Randomization of Maximal Androgen Ablation With Molecular Targeted Therapies

Completed
2
190
US
Abiraterone Acetate, CB7630, Prednisone, Sunitinib, Sunitinib Malate, SUO11248, Sutent, Dasatinib, BMS-354825, Sprycel
M.D. Anderson Cancer Center, Bristol-Myers Squibb, Janssen Scientific Affairs, LLC, Pfizer
Prostate Cancer
12/23
12/23
FORMULA-509, NCT03141671: Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP

Active, not recruiting
2
345
US
GnRH, LHRHA, Bicalutamide, Casodex, Salvage radiation, Abiraterone, Zytiga, Prednisone, Deltasone, Apalutamide, ARN-509
Dana-Farber Cancer Institute, Janssen Pharmaceutica
Prostate Cancer
04/25
12/25
NCT04267887: Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Active, not recruiting
2
7
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Antiandrogen Therapy, ADT, Androgen Deprivation Therapy, Androgen Deprivation Therapy (ADT), Anti-androgen Therapy, Anti-androgen Treatment, Antiandrogen Treatment, Hormone Deprivation Therapy, Hormone-Deprivation Therapy, Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, Bone Scan, Bone Scintigraphy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Questionnaire Administration
OHSU Knight Cancer Institute, Janssen Scientific Affairs, LLC, Oregon Health and Science University
Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
01/28
01/30
SATURN, NCT03902951: Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer

Active, not recruiting
2
28
US
Abiraterone Acetate, CB7630, Zytiga, Apalutamide, ARN 509, ARN-509, ARN509, JNJ 56021927, JNJ-56021927, Leuprolide Acetate, A-43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Procren, Procrin, Prostap, TAP-144, Trenantone, Uno-Enantone, Viadur, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation Therapy
Jonsson Comprehensive Cancer Center, Janssen Inc.
Metastatic Prostate Adenocarcinoma, Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation, Recurrent Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
01/25
01/26
NCT02949284: Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate, Gonadotropin-Releasing Hormone Analog, and Prednisone in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery

Recruiting
2
90
US
Abiraterone Acetate, CB7630, Zytiga, Androgen Receptor Antagonist ARN-509, ARN-509, Gonadotropin-releasing Hormone Analog, GnRH Agonist, GnRH Analog, Gonadotropin-Releasing Hormone Agonist, Gonadotropin-Releasing Hormone Analogue, LH-RH agonist, LH-RH Analogs, LHRH Agonist, luteinizing hormone-releasing hormone agonist, Luteinizing Hormone-Releasing Hormone Analog, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Radical Prostatectomy, Prostatovesiculectomy
Rutgers, The State University of New Jersey, National Cancer Institute (NCI)
Stage II Prostate Adenocarcinoma, Stage III Prostate Adenocarcinoma
01/24
01/24
OMPCa-ENSURE, NCT05212857: Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer

Recruiting
2
160
RoW
Leuprolide acetate, Enantone, Goserelin acetate, Zoladex, Triptorelin acetate, Diphereline, Degarelix acetate, Firmagon, Abiraterone acetate, ZYTIGA, Apalutamide, ERLEADA, Enzalutamide, Xtandi, Local treatment for primary lesion, Radiotherapy for primary lesion, Radiotherapy for metastatic lesion, Stereotactic body radiation therapy or proton and heavy ion radiation therapy
Fudan University
Prostate Cancer
02/24
09/24
NCT06241846: A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC

Recruiting
2
100
RoW
YL201 for Injection
MediLink Therapeutics (Suzhou) Co., Ltd.
Metastatic Castration-resistant Prostate Cancer (mCRPC)
02/27
02/29
NCT04986423: ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

Recruiting
2
200
US, RoW
ZEN003694, ZEN-3694, Enzalutamide, Xtandi®, MDV3100
Zenith Epigenetics, Astellas Pharma Inc, Newsoara Biopharma Co., Ltd.
Metastatic Castration-Resistant Prostate Cancer
12/24
06/25
SOLAR, NCT03298087: Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer

Completed
2
28
US
radical prostatectomy, stereotactic body radiotherapy, SBRT, Leuprolide, ADT, apalutamide, ARN-509, abiraterone, zytiga
VA Office of Research and Development
Newly Diagnosed Oligometastatic Prostate Cancer
03/24
03/24
CHOMP, NCT04104893: A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation

Recruiting
2
30
US
Pembrolizumab, Keytruda
VA Office of Research and Development, Merck Sharp & Dohme LLC
Metastatic Castration Resistant Prostate Cancer
03/25
12/25
KNIGHTS, NCT06212583: High-Risk Metachronous Oligometastatic Prostate Cancer Trial

Recruiting
2
88
US
niraparib/abiraterone acetate, Stereotactic ablative radiation therapy (SABR), Androgen deprivation therapy (ADT)
University of Maryland, Baltimore, Janssen Scientific Affairs, LLC
Prostate Cancer, Oligometastatic Disease
12/28
12/29
NCT06369610: Risk Stratified De-escalated Hormone Therapy with Radiation Therapy for the Treatment Prostate Cancer

Recruiting
2
57
US
Abiraterone Acetate, BR9004, BR9004-1, CB7630, JNJ-212082, Yonsa, Zytiga, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Gonadotropin-releasing Hormone Analog, GnRH Agonist, GnRH Analog, Gonadotropin-Releasing Hormone Agonist, Gonadotropin-Releasing Hormone Analogue, LH-RH agonist, LH-RH Analogs, LHRH Agonist, luteinizing hormone-releasing hormone agonist, Luteinizing Hormone-Releasing Hormone Analog, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Questionnaire Administration, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
Mayo Clinic
Oligometastatic Prostate Carcinoma, Prostate Adenocarcinoma
04/27
04/27
NCI-2018-01054, NCT03360721: Apalutamide, Abiraterone Acetate, and Prednisone in Treating Participants With Metastatic Castration Resistant Prostate Cancer

Active, not recruiting
2
7
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Castration-Resistant Prostate Carcinoma, Prostate Adenocarcinoma Without Neuroendocrine Differentiation, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
04/25
04/25
NCT04926155: The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

Not yet recruiting
2
234
RoW
Metformin, Metformin Hydrochloride Sustained Release Tablets
Sun Yat-sen University
Metastatic Prostate Cancer
04/24
08/24
NCT06145308: Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing

Recruiting
2
30
RoW
Vedolizumab, larotinib or enttraitinib, antiandrogen drug treatment, leprerelin + bicalutamide ± Abiraterone 1000mg po qd, ESG401, small molecule multi-target tyrosine kinase inhibitors± Chemioterapy, apatinib or erlotinib, albumin paclitaxel with platinum
Peking Union Medical College, Peking University Hospital of Stomatology
Locally Advanced or Recurrent/Metastatic Salivary Gland Carcinoma, Neoadjuvant or Conversion Therapy, Precision Therapy
07/26
07/26
ChiCTR2200060566: An exploratory clinical study of fluzoparib combined with abiraterone in preoperative neoadjuvant treatment of high-risk localized prostate cancer and oligometastatic prostate cancer

Not yet recruiting
2
31
 
Fluzoparib +abiraterone
Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Own
Prostate cancer
 
 
DIVINE, NCT06378866: Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, Trial

Recruiting
2
120
US
Abiraterone, Abiraterone acetate, CB-7598, CB7598, Zytiga, Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography (CAT), Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Darolutamide, Antiandrogen ODM-201, BAY 1841788, BAY-1841788, BAY1841788, Nubeqa, ODM 201, ODM-201, Degarelix, ASP3550, FE200486, Firmagon, Enzalutamide, ASP9785, MDV3100, Xtandi, Goserelin, ICI-118630, Histrelin, Leuprolide, Leuprorelin, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, Nuclear Magnetic Resonance (NMR) Imaging, NMRI, Nuclear Magnetic Resonance Imaging (NMRI), sMRI, Structural MRI (sMRI), NMR Imaging, Patient Observation, Active Surveillance, deferred therapy, expectant management, Observation, Watchful Waiting, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron Emission Tomography (PET), Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Questionnaire Administration, Relugolix, N-(4-(1-((2,6-Difluorophenyl)methyl)-5-((dimethylamino)methyl)-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno(2,3-d)pyrimidin-6-yl)phenyl)-N'-methoxyurea, Orgovyx, Relumina, TAK 385, TAK-385, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation (SABR), Stereotactic Ablative Body Radiation Therapy, Triptorelin, 6-D-Tryptophan-LH-RH, 6-D-Tryptophanluteinizing Hormone-releasing Factor, AY-25650, AY25650, CL-118,532, CL118532, Detryptoreline
Mayo Clinic
Recurrent Castration-Sensitive Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8, Recurrent Prostate Cancer, Castration-resistant Prostate Cancer
05/29
05/29
SYNERGY-201, NCT06228053: Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer

Recruiting
2
53
US
SX-682, Enzalutamide, Xtandi
Syntrix Biosystems, Inc., National Cancer Institute (NCI)
Metastatic Castration-resistant Prostate Cancer
06/26
06/28
ChiCTR2200061643: Efficacy and safety of bipolar androgen therapy in mCRPC after progression on abiraterone or docetaxel: a prospective single-arm clinical study based on Chinese populations

Not yet recruiting
2
86
 
Testosterone propionate
West China Hospital of Sichuan University; West China Hospital of Sichuan University, West China Hospital of Sichuan University
Prostate Cancer
 
 
CHAARTED2, NCT03419234: Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

Active, not recruiting
2
223
US
Abiraterone Acetate, CB7630, Zytiga, Antiandrogen Therapy, ADT, Androgen Deprivation Therapy, Anti-androgen Therapy, Anti-androgen Treatment, Antiandrogen Treatment, Hormone Deprivation Therapy, Hormone-Deprivation Therapy, Cabazitaxel, Jevtana, RPR-116258A, Taxoid XRP6258, XRP-6258, Laboratory Biomarker Analysis, Orchiectomy, Castration, Male Castration, Male Gonadectomy, orchidectomy, Pharmacological Study, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma in the Soft Tissue, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Adenocarcinoma AJCC v7
12/24
04/26
Flu-BLAST-PC, NCT04175431: Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Study

Recruiting
2
100
US
Positron Emission Tomography, Medical Imaging, PET Scan, positron emission tomography scan, proton magnetic resonance spectroscopic imaging, Positron-Emission Tomography, Lymphadenectomy, Lymph Node Dissection, lymph node excision, excision of the lymph node, Radiation Therapy, Cancer Radiotherapy, Irradiation, Radiotherapeutics, RT, ENERGY_TYPE, Irradiated, Therapy, Radiation, NOS, Abiraterone Acetate, 154229-18-2, Yonsa, Zytiga, Androsta-5, Prednisone, Deltasone, Prednicort, Prednisone Intensol, Rayos, Sterapred, Dehydrocortisone, Prednilonga, Servisone, Computed Tomography, CAT Scan, CAT, computerized axial tomography, computerized tomography, CT Scan, Abiraterone, 154229-19-3, 17-(3-Pyridyl)androsta-5, 16-dien-3beta-ol, CB 7598, PSMA PET Scan, Prostate-specific Membrane Antigen PET, PSMA PET, PSMA-Positron emission tomography
University of Washington, Blue Earth Diagnostics
Prostate Adenocarcinoma
07/26
07/31
TEAM PC, NCT06582628: Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer:

Recruiting
2
78
Europe
Enzalutamide capsule, Enzalutamide capsule and Talazoparib capsule
Fundacion Oncosur
Metastatic Prostate Cancer
01/26
10/27
CABPOSTAAT, NCT03764540: Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamide

Active, not recruiting
2
214
Canada
Cabazitaxel plus prednisone, Experimental, Docetaxel plus prednisone, Active Comparator
Centre hospitalier de l'Université de Montréal (CHUM), Genzyme, a Sanofi Company
Metastatic Prostate Cancer
12/24
12/24
NCT03581500: Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Predicting Treatment Response in Patients With Prostate Cancer

Withdrawn
2
2
US
Hyperpolarized Carbon C 13 Pyruvate, Hyperpolarized 13C-Pyruvate, Hyperpolarized Pyruvate (13C), Magnetic Resonance Spectroscopic Imaging, 1H- Nuclear Magnetic Resonance Spectroscopic Imaging, 1H-nuclear magnetic resonance spectroscopic imaging, Magnetic Resonance Spectroscopy, MRS, MRS Imaging, MRSI, Proton Magnetic Resonance Spectroscopic Imaging
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Prostate Adenocarcinoma, PSA Level Greater Than Ten, Stage IIB Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
10/24
10/24
NCT06500247: Darxicilib Combined With Abiraterone Acetate Tablets (II) for the Treatment of Advanced Metastatic Castration-resistant Prostate Cancer.

Not yet recruiting
2
43
RoW
Dalpicilib, Abiraterone Acetate (II), Androgen Deprivation Therapy, Prednisone
Qilu Hospital of Shandong University, Jiangsu HengRui Medicine Co., Ltd.
The Efficacy of Abiraterone Acetate Combined With Dalpicilib in the Treatment of Patients With Metastatic Castration-resistant Prostate Cancer
03/27
03/27
NCI-2018-02551, NCT03725761: Sacituzumab Govitecan in Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Second Generation AR-Directed Therapy

Active, not recruiting
2
31
US
Sacituzumab Govitecan, IMMU-132
University of Wisconsin, Madison, National Cancer Institute (NCI), Gilead Sciences
Prostate Cancer
04/24
04/25
NCT06505278: The Impact of Medication Timing Adjustment on the Effect of Novel Hormonal Therapy

Not yet recruiting
2
70
RoW
Receive Abiraterone plus prednisone/Enzalutamide/Apalutamide/Rezvilutamide in the evening
Sun Yat-sen University
Prostate Cancer
03/25
12/25
NCT05689021: CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Recruiting
2
30
US
Abiraterone Acetate/Niraparib, Abiraterone Acetate and Niraparib Tosylate Monohydrate, Abiraterone Acetate/Niraparib Tosylate Monohydrate, Akeega, CJNJ-67652000, Niraparib and Abiraterone Acetate, Niraparib Tosylate Monohydrate and Abiraterone Acetate, Niraparib Tosylate Monohydrate/Abiraterone Acetate, Niraparib/Abiraterone Acetate, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
Mayo Clinic
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
09/24
09/25
CTUSMEP01, NCT06655259: Combination of TURP and Standard Systemic Therapy for MPCa

Recruiting
2
200
RoW
TURP, Standard Medical Therapy
Fudan University
Metastatic Prostate Cancer
09/26
12/26
NCT06384222: Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Not yet recruiting
2
32
US
Abiraterone acetate, Abiraterone, Zytiga, Prednisone, Rayos, Hyperpolarized [1-13C] pyruvate (HP 13C), Hyperpolarized 13C, Magnetic Resonance Imaging (MRI), MRI, MR, Non-investigational radical prostatectomy (RP), Radical prostatectomy, Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) PET/Computerized tomography (CT)
Ivan de Kouchkovsky, MD
High Risk Prostate Carcinoma, Prostate Cancer
07/27
07/27
NCT03821792: Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer

Active, not recruiting
2
60
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
10/26
10/26
PREDICT, NCT06632977: Targeted Treatment for Metastatic Prostate Cancer, The Trial

Not yet recruiting
2
474
NA
Genetic testing, Valemetostat Tosylate, Magnetic Resonance Imaging, MRI, Computed Tomography, CAT Scan, CT Scan, Bone scan, FDG-Positron Emission Tomography, PSMA PET Scan, Prostate-specific Membrane Antigen PET, Biospecimen Collection, Carboplatin, Cabazitaxel, Abiraterone Acetate, Enzalutamide, Xtandi, Lutetium Lu 177 Vipivotide Tetraxetan, Pluvicto
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
04/30
10/34
NCT03007732: Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT

Active, not recruiting
2
23
US
Pembrolizumab, MK-3475, Keytruda, SD-101, Toll-like receptor 9, Leuprolide acetate, Intermittent androgen deprivation therapy, Abiraterone Acetate, Prednisone, Stereotactic Body Radiation Therapy, SBRT
David Oh, Prostate Cancer Foundation, Merck Sharp & Dohme LLC, TriSalus Life Sciences, Inc.
Prostatic Neoplasms
10/24
10/24
APRE, NCT03833921: Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer

Recruiting
2
130
US
Abiraterone Acetate, Zytiga, Prednisone
Martha Mims
Prostate Cancer Metastatic, Prostate Cancer
11/24
04/34
REPRESENTATION, NCT06527690: Race Impact on Efficacy of Niraparib Plus Abiraterone Acetate and Prednisone in Patients With Homologous Repair Deficient Castration-resistant Prostate Cancer

Not yet recruiting
2
70
NA
Niraparib/Abirate rone acetate fixed-dose combination, Prednisone
Latin American Cooperative Oncology Group, Janssen, LP
Prostate Cancer, Castrate Resistant Prostate Cancer, Homologous Recombination Deficiency
09/27
02/29
PROact, NCT05167175: The Study of Olaparib Combined With Abiraterone and Prednisone in mHSPC Patients With HRR Gene Mutation

Recruiting
2
30
RoW
Olaparib tablet, Lynparza, Abiraterone acetate, Qingkeshu, Prednisone tablet
Hongqian Guo, AstraZeneca, Nanjing Chia-tai Tianqing Pharmaceutical
Prostate Cancer, Prostate Carcinoma, Metastatic Prostate Cancer
12/24
12/24
HARMONY, NCT06392841: Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations

Not yet recruiting
2
64
NA
Androgen Deprivation Therapy (ADT), Niraparib/Abiraterone Acetate DAT, Akeega, Abiraterone Acetate, Zytiga, Prednisone, Rayos, Deltasone, Prednisone Intensol, Docetaxel, Docefrez, Taxotere
Qian Qin, UT Southwestern Comprehensive Cancer Center, Janssen, LP
Metastatic Hormone-sensitive Prostate Cancer (mHSPC), Deleterious HRR Gene Mutation, BRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation, CHEK2 Gene Mutation, FANCA Gene Mutation, PALB2 Gene Mutation, RAD51B Gene Mutation, RAD54L Gene Mutation
04/27
04/28
NCT06616597: Phase II Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer

Not yet recruiting
2
58
US
Abiraterone acetate, Dexamethasone, Metronidazole, Flagyl
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer (Adenocarcinoma), Metastatic Prostate Cancer
12/30
12/30
LoMP II, NCT03655886: Cytoreductive Prostatectomy Versus Cytoreductive Prostate Irradiation as a Local Treatment Option for Metastatic Prostate Cancer: a Multicentric Feasibility Trial

Recruiting
2
86
Europe
radical prostatectomy, Whole pelvis radiotherapy
University Hospital, Ghent
Prostate Cancer Metastatic
12/24
12/24
NCT04992026: The Efficacy and Safety of Prostatectomy for Castration-Naive Oligometastatic Prostate Cancer

Active, not recruiting
2
128
RoW
robot assisted laparoscopic prostatectomy + enlarged pelvic lymph node dissection, 1.Abiraterone Acetate Tablets, Prednisone Acetate Tablets, Luteinizing Hormone-Releasing Hormone Analog
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, The Affiliated Hospital of Xuzhou Medical University, The First People's Hospital of Changzhou, The First Affiliated Hospital of Soochow University, Wuxi People's Hospital, The Affiliated Hospital of Nantong University, The Affiliated Hospital of Yangzhou University
Prostatectomy, Oligometastatic Prostate Cancer, Abiraterone
01/25
05/25
J2258, NCT05574712: A Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate Cancer

Withdrawn
2
30
NA
Neoadjuvant treatment, leuprolide acetate, abiraterone acetate, belzutifan
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
01/25
07/26
NCI-2018-01856, NCT01786265: Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer

Active, not recruiting
2
310
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Bicalutamide, Casodex, Cosudex, ICI 176,334, ICI 176334, Degarelix, FE200486, Firmagon, Flutamide, 4''-Nitro-3''-trifluoromethylisobutyranilide, Apimid, Cebatrol, Chimax, Cytomid, Drogenil, Euflex, Eulexine, Flucinom, Flucinome, Flugerel, Fluken, Flulem, FLUT, Fluta-Gry, Flutabene, Flutacan, Flutamex, Flutamin, Flutan, Flutaplex, Fugerel, Grisetin, Niftolide, Oncosal, Profamid, Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, Prostacur, Prostadirex, Prostica, Prostogenat, Sch 13521, Tafenil, Tecnoflut, Testotard, Goserelin Acetate, ZDX, Zoladex, Leuprolide Acetate, A-43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Lutrate, Procren, Procrin, Prostap, TAP-144, Trenantone, Uno-Enantone, Viadur, Nilutamide, Anandron, Nilandron, RU-23908, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
M.D. Anderson Cancer Center
Prostate Adenocarcinoma, Recurrent Prostate Carcinoma
02/25
02/25
NCT03436654: Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma

Active, not recruiting
2
102
NA
Apalutamide, ARN-509, ERLEADA™, Abiraterone Acetate, ZYTIGA, Prednisone, Radical Prostatectomy, Extended Pelvic lymphadenectomy, GnRH agonist/antagonist, Stereotactic Body Radiation Therapy
Memorial Sloan Kettering Cancer Center, Dana-Farber Cancer Institute
Prostate Cancer
02/25
02/25
PROTRACT, NCT04015622: PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA

Recruiting
2
100
Canada
Enzalutamide, Xtandi, Docetaxel, Taxotere
British Columbia Cancer Agency
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
04/25
12/25
CASCARA, NCT03934840: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone

Active, not recruiting
2
22
US
Cabazitaxel, Carboplatin, Abiraterone, Prednisone
Masonic Cancer Center, University of Minnesota
Prostate Cancer
06/23
05/25
FAALCON, NCT04748042: Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towards Castration Sensitive Oligometastatic Prostate Cancer

Recruiting
2
29
US
Abiraterone, Zytiga, Prednisone, External Beam Radiotherapy, Androgen Deprivation Therapy (ADT), Olaparib, Lynparza, AZD2281
University of Michigan Rogel Cancer Center
Prostate Cancer, Castrate Sensitive Prostate Cancer, Oligometastatic Disease
05/25
05/25
NCT05189457: First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer

Active, not recruiting
2
32
US
Luteinizing Hormone Releasing Hormone, Leuprolide, Triptorelin, Goserslin, Relugolix, Degarelix, New Hormonal Agent, Abiraterone, Enzalutamide, Docetaxel, Tislelizumab, BGB-A317
H. Lee Moffitt Cancer Center and Research Institute, BeiGene
Prostate Cancer, Stage IV Prostate Cancer
07/27
07/28
DynaMO, NCT02703623: Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

Active, not recruiting
2
196
US
Abiraterone Acetate, CB7630, Zytiga, Apalutamide, ARN 509, ARN-509, ARN509, JNJ 56021927, JNJ-56021927, Cabazitaxel, Jevtana, RPR-116258A, Taxoid XRP6258, XRP-6258, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS-734016, MDX-010, MDX-CTLA4, Yervoy, Laboratory Biomarker Analysis, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, PSA Progression, Stage IV Prostate Adenocarcinoma AJCC v7
03/26
03/26
NCT05422911: Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

Not yet recruiting
2
200
US
Abiraterone acetate, Apalutamide, Enzalutamide
James J. Peters Veterans Affairs Medical Center
Metastatic Cancer, Neoplasm, Prostate
06/25
06/26
NCT03860987: Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer

Active, not recruiting
2
11
US
goserelin, Enzalutamide, Abiraterone, 18F-DCFPyL, Prednisone, Radical Prostatectomy
National Cancer Institute (NCI)
Castrate Sensitive Prostate Cancer
08/25
08/28
NCT05588609: Study Evaluating Zenocutuzumab in Patients with or Without Molecularly Defined Cancers

Active, not recruiting
2
90
US
Afatinib Oral Tablet, GILOTRIF®, GIOTRIF®, Enzalutamide Pill, XTANDI®, Abiraterone acetate tablets, ZYTIGA®, MCLA-128, Zenocutuzumab
Merus N.V.
NSCLC Harboring NRG1 Fusion, Metastatic Castration-resistant Prostate Cancer
10/25
03/26
NCT05751941: Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer

Recruiting
2
26
US
Abiraterone, Enzalutamide, Xtandi, Apalutamide, Sipuleucel-T, Provenge
H. Lee Moffitt Cancer Center and Research Institute, Dendreon
Prostate Cancer, Metastatic Prostate Cancer
10/24
10/25
NCT06015321: An Open Label Phase II Study of First-Line Maintenance Enzalutamide Following Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Castration-Naive Prostatic Adenocarcinoma

Not yet recruiting
2
51
RoW
Enzalutamide, XtandiTM
Samsung Medical Center
Prostatic Adenocarcinoma
10/25
04/26
 

Download Options