| trazodone ER / Generic mfg. |
ChiCTR-IPR-16009475: The research of chronic insomnia clinical evaluation and optimization of treatment |
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| Completed | 4 | 100 | | alprazolam ;Zolpidem ;Trazodone ;Quetiapine | Shanghai Mental Health Center; Shanghai Mental Health Center, Shanghai science and technology committee | chronic insomnia | | | | |
ChiCTR-IPR-14005681: Effective evaluation of trazodone in treatment of sleep disorders and mood disorder for methamphetamine addicts after detoxification |
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| Recruiting | 4 | 120 | | trazodone ;Placebo | Ningbo Addiction Research and Treatment Center; None, National Key Technology R&D Program in the 12th Five-Year Plan of China (2012BAI01B07) | methamphetamine dependence | | | | |
2006-000216-24: Serotonin sensitivity in insomnia: a placebo-controlled crossover study of sleep after 5HT2 blockade in primary insomnia. |
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| Ongoing | 4 | 12 | Europe | trazodone, Molipaxin Trazodone hydrochloride, Molipaxin Trazodone hydrochloride | University of Bristol | Primary insomnia | | | | |
| Recruiting | 4 | 66 | | Trazodone + Jiuwei Zhenxin Granules ;Trazodone + Jiuwei Zhenxin Granules Simulant | Henan Provincial Psychiatric Hospital; Henan Provincial Psychiatric Hospital, Beijing Beilu Pharmaceutical Co., Ltd | Anxiety Depression | | | | |
| Active, not recruiting | 4 | 155 | US | Zolpidem, Ambien, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), SHUTi, Trazodone, Desyrel | California Pacific Medical Center Research Institute, Patient-Centered Outcomes Research Institute, University of Pittsburgh, University of Arizona, University of Virginia, University of Illinois at Chicago | Chronic Insomnia | 06/24 | 06/24 | | |
NCT02922894: Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury |
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| Recruiting | 4 | 100 | US | Acute episodic hypoxia, Supplemental oxygen, Trazodone, Placebo, Sham | John D. Dingell VA Medical Center, United States Department of Defense | Sleep Apnea, Spinal Cord Injury | 05/24 | 06/24 | | |
| Not yet recruiting | 4 | 30 | US | Trazodone, Desyrel, Quetiapine, Seroquel, Placebo | University of Southern California | Delirium, Morality, Quality of Life, Psych, Treatment Side Effects | 07/26 | 12/26 | | |
| Recruiting | 4 | 124 | RoW | Trazodone, Placebo | Chinese University of Hong Kong, Hong Kong University of Science and Technology | Mild Cognitive Impairment, Obstructive Sleep Apnea | 12/24 | 12/26 | | |
| Recruiting | 3 | 774 | US | Trazodone, Eszopiclone, Placebo | VA Office of Research and Development | Insomnia | 02/26 | 02/26 | | |
| Recruiting | 2/3 | 800 | Europe | Memantine Hydrochloride Oral Solution, Trazodone Hydrochloride oral solution, Placebo oral solution, Amantadine Hydrochloride Oral Solution | University of Edinburgh, University College, London, University of Warwick, NHS Lothian | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | 09/26 | 12/26 | | |
REST, NCT05282550: Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone |
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| Recruiting | 2 | 100 | US | Trazodone, Desyrel, Placebo | Johns Hopkins University, National Institute on Aging (NIA) | AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance | 03/27 | 05/28 | | |
NCT05299398: Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of Trazodone |
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| Not yet recruiting | 1 | 28 | Canada | Trazodone, Placebo | Verinder Sharma | Postpartum Depression | 07/23 | 03/24 | | |
NCT06281756: Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia |
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| Recruiting | 1 | 600 | Canada, US | Cognitive Behavioral Treatment for Insomnia (CBT-I), Trazodone, Placebo | Milton S. Hershey Medical Center, National Heart, Lung, and Blood Institute (NHLBI) | Insomnia, Insomnia Chronic, Insomnia, Primary, Blood Pressure, Blood Pressure, High | 02/27 | 02/28 | | |
ChiCTR2100041872: Metabonomics study of virtual Reality VR assisted trazodone in the treatment of insomnia disorder |
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| Recruiting | N/A | 90 | | Nil ;drug +VR ;drug | Jiading District Central Hospital affiliated to Shanghai Health Medical College; Jiading District Central Hospital affiliated to Shanghai Health Medical College, Shanghai Jiading District Health Commission | Insomnia disorders | | | | |
NCT05125146: Investigating the Effectiveness of e-CBTi Compared to Pharmaceutical Interventions in Treating Insomnia |
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| Recruiting | N/A | 60 | Canada | e-CBTi, Electronically-Delivered CBT, Trazodone, Control | Dr. Nazanin Alavi, Online PsychoTherapy Clinic | Insomnia | 07/24 | 12/24 | | |
ChiCTR2100042845: Community Promotion and Application of Wuqinxi combined with brief behavioral therapy for insomnia |
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| Recruiting | N/A | 98 | | Wuqinxi and other external therapies plus behavioral therapy ;Trazodone hydrochloride plus behavioral therapy | Jiangsu Vocational College of Medicine; Jiangsu Vocational College of Medicine, Jiangsu Vocational College of Medicine | insomnia | | | | |
ChiCTR2000034739: Study on the optimization of treatment scheme for patients with chronic insomnia |
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| Not yet recruiting | N/A | 180 | | trazodone ;Mirtazapine ;Fluvoxamine ;CBTI combined with hypnotic therapy ;Agomelatine ;nothing | The Second Affiliated Hospital of Xinxiang Medical University; The Second Affiliated Hospital of Xinxiang Medical University, Not available | Non-organic insomnia | | | | |
| Recruiting | N/A | 60 | US | Trazodone, Desyrel, Quetiapine, Seroquel | University of Southern California | Delirium, Delirium of Mixed Origin, Delirium, Sepsis Associated, Delirium in Old Age, Delirium Confusional State, Psych, Morality, Treatment Side Effects | 08/25 | 12/25 | | |
