| Combigan (brimonidine tartrate/timolol maleate) / AbbVie |
| Completed | N/A | 64 | Canada | | DBYAN Medicine Professional Corporation, Allergan | Open Angle Glaucoma, Ocular Hypertension | 02/08 | 02/08 | | |
NCT00706927: Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension |
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| Completed | N/A | 16 | Europe | latanoprost 0.005% + timolol 0,5% fixed combination, Xalacom® (latanoprost/timolol), brimonidine 0,2% + timolol 0,5% fixed combination, Combigan® (brimonidine/timolol) | Medical University of Vienna | Retina, Ocular Physiology | 08/10 | 09/10 | | |
NCT01229462: Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension |
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| Completed | N/A | 238 | RoW | brimonidine tartrate/timolol fixed combination ophthalmic solution, Combigan®, brimonidine tartrate ophthalmic solution, Alphagan®, timolol ophthalmic solution, fixed combination vehicle | Allergan | Glaucoma, Ocular Hypertension | 09/11 | 09/11 | | |
NCT01987752: Safety and Efficacy of Combigan® Ophthalmic Solution in Korea |
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| Completed | N/A | 732 | RoW | brimonidine tartrate/timolol maleate Ophthalmic Solution, Combigan® | Allergan | Glaucoma, Open-Angle, Ocular Hypertension | 11/11 | 11/11 | | |
NCT00824824: Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG) |
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| Completed | N/A | 21 | US | Dorzolamide 2%-timolol 0.5%, Cosopt, RVD intervention after run-in on timolol 0.5% bid OU, Brimonidine 0.2%-0.5% timolol 0.5, Combigan | Massachusetts Eye and Ear Infirmary | Glaucoma | 08/12 | 08/12 | | |
NCT02718547: The Relationship Between Intraocular Pressure and Macular Edema in Patients With Diabetic Macular Edema |
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| Unknown status | N/A | 25 | RoW | Combigan, brimonidine tartrate/timolol maleate ophthalmic solution | Meir Medical Center, Meir Hospital, Kfar Saba, Israel | Complications of Diabetes Mellitus | 03/18 | 07/18 | | |
NCT02623023: Prophylaxis for Anti-VEGF-induced IOP Elevation |
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| Withdrawn | N/A | 107 | NA | Combigan, (Combigan®, Refresh tears | McMaster University | Ocular Hypertension | 01/19 | 01/19 | | |
