| Estrace (estradiol) / AbbVie |
DRIVE, NCT00465894: Detrol Long Acting (LA) vs Estrace Vaginal Cream for the Treatment of Overactive Bladder Symptoms |
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| Completed | N/A | 58 | NA | Extended Release Tolterodine LA, Detrol, Intra Vaginal Estradiol Cream, Estrace, Premarin vaginal cream | University of Alabama at Birmingham, Pfizer | Overactive Bladder | 07/10 | 12/11 | | |
NCT01418209: MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms |
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| Completed | N/A | 339 | US | Low-dose 17-ß-estradiol with progesterone taper, The brand name of estradiol being used in this study is Estrace®., Venlafaxine XR, The brand name of venlafaxine XR that is being used in this study is Effexor XR®, Placebo | Fred Hutchinson Cancer Center, National Institute on Aging (NIA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Center for Complementary and Integrative Health (NCCIH), Office of Research on Women's Health (ORWH) | Hot Flashes, Menopause, Vasomotor Disturbance | 01/13 | 01/13 | | |
NCT01428245: Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition |
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| Terminated | N/A | 3 | US | Progesterone, Estrace (estrogen), estradiol | University of Virginia, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Hyperandrogenemia, Polycystic Ovary Syndrome | 05/13 | 05/13 | | |
NCT01023178: Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure |
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| Completed | N/A | 20 | US | 17beta Estradiol, Estrace, Conjugated estrogens, Premarin, 17Beta Estradiol - transdermal, Vivelle-Dot, Progesterone, micronized, Prometrium | Stanford University | Ovarian Failure, Premature | 06/13 | 06/13 | | |
NCT01427595: Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone |
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| Completed | N/A | 25 | US | Metformin, Progesterone, estrace, Estrogen | University of Virginia, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Polycystic Ovary Syndrome, Hyperandrogenism | 01/15 | 01/15 | | |
| Completed | N/A | 43 | US | Estradiol cream 0.01%, Estrace Vaginal, Cetaphil | Children's Mercy Hospital Kansas City, University of Missouri, Kansas City | Prepubertal Labial Adhesions | 05/16 | 06/16 | | |
NCT01762943: Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition |
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| Completed | N/A | 36 | US | Leuprolide Acetate, Lupron, Micronized estradiol, Estrace, Progesterone, Micronized progesterone | University of North Carolina, Chapel Hill, Foundation of Hope, North Carolina, North Carolina Translational and Clinical Sciences Institute, National Institutes of Health (NIH), National Alliance for Research on Schizophrenia and Depression, National Institute of Mental Health (NIMH) | Postpartum Depression | 10/16 | 10/16 | | |
NCT01428193: Effects of Androgen Blockade on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone |
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| Terminated | N/A | 4 | US | Flutamide, Progesterone, estrace, (estradiol) | University of Virginia, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Polycystic Ovary Syndrome, Hyperandrogenism | 08/17 | 08/17 | | |
NCT04544475: A Randomized, Single Center Pilot Study Comparing Hyaluronic Acid to Vaginal Estrogen for Treatment of Genitourinary Syndrome of Menopause |
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| Completed | N/A | 49 | US | Revaree, HLA Vaginal Insert, Estrace, Vaginal estrogen cream | NYU Langone Health, JDS Therapeutics, LLC | Genitourinary Syndrome of Menopause (GSM) | 10/22 | 10/22 | | |
NCT04301934: Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection |
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| Completed | N/A | 12 | US | Mona Lisa Touch, Conjugated estrogen, Premarin, Estradiol, Estrace | Mayo Clinic | Urinary Tract Infections | 04/23 | 04/23 | | |
VITAL-E, NCT05672901: Silicone Gel Vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause |
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| Recruiting | N/A | 100 | US | StrataMGT, Estrace 0.01% Vaginal Cream | Stratpharma AG | Genitourinary Syndrome of Menopause | 11/25 | 11/25 | | |
NCT01425541: Assessment of the Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition |
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| Active, not recruiting | N/A | 60 | US | estrace, Estrogen, Progesterone | University of Virginia, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Hyperandrogenemia, Polycystic Ovary Syndrome (PCOS) | 08/25 | 08/25 | | |
