| Chirocaine (levobupivacaine) / Purdue, AbbVie |
ChiCTR-TRC-09000685: Comparative pharmacokinetics after thoracic paravertebral administration of levobupivacaine with or without epinephrine |
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| Completed | N/A | 20 | | Plain levobupivacaine or levobupivacaine with epinephrine Plain levobupivacaine or levobupivacaine with epinephrine versus Levobupivacaine or Levobupivacaine with epinephrine | Dept of Anaesthesia and Inteneive Care, CUHK; Level of the institution:, Departmental Sources | nil | | | | |
NCT01349751: Clinical Characteristics of Spinal Levobupivacaine: Hyperbaric Compared With Isobaric Solution |
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| Completed | N/A | 20 | RoW | isobaric levobupivacaine, Chirocaine, Abbott Laboratories, Nycomed Pharma AS, Norway, hyperbaric levobupivacaine | Mahidol University | Observation of Neuromuscular Block, Disease (or Disorder); Gynecological | 02/08 | 02/08 | | |
NCT00636974: A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia |
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| Completed | N/A | 75 | RoW | Combined spinal epidural anaesthesia | Hospital Authority, Hong Kong | Anesthesia, Conduction, Surgery | | 07/08 | | |
NCT01105442: Local Anaesthesia Used During Fast-track Colonic Surgery: Evaluation of Bupivacaine and Levobupivacaine in Practice |
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| Completed | N/A | 14 | Europe | | Martini Hospital Groningen | Colonic Diseases, Post-operative Pain, Local Anesthesia | 06/10 | 07/10 | | |
NCT07285759: Investigation of Antibacterial Effect of Levobupivacaine on Staphylococcus Aureus |
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| Completed | N/A | 40 | NA | Levobupivacaine, Fentanyl, Saline | Dokuz Eylul University | Staphylococcus Aureus Bacterial Contamination | 02/11 | 02/11 | | |
NCT02478372: Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty |
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| Completed | N/A | 242 | Europe | Patient Controlled Epidural (PCEA), Levobupivacaine and Bupivacaine, Local Infiltration Analgesia (LIA), Ropivacaine | Golden Jubilee National Hospital, Glasgow Caledonian University | Osteoarthritis | 08/11 | 11/12 | | |
NCT00830089: Trial of a Transversus Abdominis Plane (TAP) Block in Laparoscopic Colorectal Surgery |
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| Completed | N/A | 66 | Europe | Levobupivicaine 0.25%, Chirocaine | University of Nottingham | Post-operative Pain, Postoperative Nausea, Postoperative Complications | 09/11 | 12/11 | | |
NCT01305733: Local Infiltration Analgesia During Total Knee Arthroplasty |
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| Unknown status | N/A | 60 | Europe | The injectant mixture consists of 150 mg levobupivacaine mixed with 30 mg ketorolac and 0.5 mg adrenaline, saline injection | Coxa, Hospital for Joint Replacement | Pain | 05/12 | 12/12 | | |
| Unknown status | N/A | 40 | RoW | Trigeminal nerve block, 5ml Chirocaine, 2.5ml Chirocaine, Placebo | Chang Gung Memorial Hospital | Postoperative Pain | 06/12 | 12/12 | | |
NCT01974843: Caudal Block With Tramadol and Levobupivacaine or Bupivacaine |
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| Completed | N/A | 68 | RoW | Levobupivacaine, Chirocaine, Abbott Lab, Nycomed Pharma, Norway, Bupivacaine, Marcaine, Astra Zeneca, UK | Duzce University | Pain, Postoperative | 10/12 | 01/13 | | |
NCT01467596: Ultrasound-guided Supraclavicular Brachial Plexus Block in Elderly |
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| Completed | N/A | 44 | RoW | Elderly population, Middle aged population, Levobupivacaine 0.5%, Lidocaine 2% | Šarić, Jadranka Pavičić, M.D. | Arm Injuries, Anesthesia | 11/12 | 11/12 | | |
ChiCTR-TRC-09000773: A random-allocation graded dose-response study of intrathecal bupivacaine, levobupivacaine and ropivacaine for labor analgesia in nulliparous women |
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| Recruiting | N/A | 270 | | Labouring patients randomized to an intrathecal dose ranging from 0.625 to 6.25 mg of either bupivacaine, levobupivacaine or ropivacaine. Response measured as pain scores for 15 min | Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong; Level of the institution:, Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong | Labour | | | | |
NCT01739270: Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia |
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| Unknown status | N/A | 55 | RoW | supraclavicular brachial plexus block | University Hospital Dubrava | Brachial Plexus Anesthesia, Analgesia | 01/13 | | | |
ChiCTR-TRC-12002753: Effect of dexmedetomidine on the potency of levobupivacaine for caudal block in young children |
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| Completed | N/A | 105 | | caudal levobupivacaine ;levobupivacaine and 1ug/kg dexmedetomidine ;levobupivacaine and 1ug/kg dexmedetomidine | Guangzhou Women and Childrens Medical Center; Guangzhou women and chilren's medical center, self-financing | inguinal hernia andhydrocele in children | | | | |
NCT01860521: Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia |
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| Completed | N/A | 104 | Europe | Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Procedure of interruption of pregnancy, Drug used for analgesia procedures, Levobupivacaine: Chirocaine®, Abbott, Chicago, IL, USA., Sufentanil: Fentatienil®, Angelini, Rome, Italy., Pump for programmed intermittent bolus., Pump: Gemstar®; Hospira, Lake Forest, USA., Pump for continuous epidural infusion., Drug used for termination of pregnancy procedure., Gemeprost pessaries: Cervidil®, Merck Serono SPA, Rome, Italy. | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | Medical; Abortion, Fetus | 06/13 | 06/13 | | |
NCT02057601: Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic |
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| Completed | N/A | 37 | Europe | Levobupivacaine infiltration group | Cork University Hospital | Fractured Neck of Femur, Postoperative Pain | 06/13 | 06/13 | | |
ChiCTR-TRC-12002752: A prospective study comparing the onset andanalgesic efficacy of different concentrations levobupivacaine or with dexmedetomidine in young children undergoing caudal blockade |
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| Completed | N/A | 210 | | 0.25%levobupivacaine ;0.20%levobupivacaine ;0.20%levobupivacaine and 2ug/kg dexmedetomidine | Guangzhou Women andChildrens Medical Center; guangzhou women and children's medical center, self-financing | inguinal hernia andhydrocele in children | | | | |
| Completed | N/A | 120 | RoW | parasternal block, Levobupivacaine, TENS group, TENS device, control group, PCA device | Antalya Training and Research Hospital | Postoperative Pain | 08/13 | 12/13 | | |
NCT01734954: Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery |
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| Unknown status | N/A | 66 | RoW | Sciatic nerve anesthesia blockade at bifurcation., Sciatic Nerve Block, Sciatic nerve blockade 2 cm beyond the bifurcation, Sciatic nerve block, Levobupivacaine 0.5%: 20 ml, Local Anesthetic, Portable Ultrasound Machine: Sonosite, M-Turbo, Bothell, WA, Ultrasound, Insulated Needle, (Stimuplex; Braun, Melsungen, Germany), Nerve blockade needle short bevel., supplemental oxygen, oxygen, Midazolam, Intravenous analgesics, Saphenous nerve block | CES University, Hospital Pablo Tobón Uribe, Clínica CES | Anesthesia | 08/13 | 09/13 | | |
| Completed | N/A | 46 | Europe | Fascia Iliaca Compartment Block (FICB), Local Anaesthetic Infiltration (LAI), Levobupivacaine | Cambridge University Hospitals NHS Foundation Trust | Femoroacetabular Impingement | 11/13 | 04/14 | | |
ChiCTR-TRC-13002993: Effect of caudal levobupivacaine mixed with ketamine andfentanyl on MAC-BAR of sevoflurane andpostoperative analgesia in Chinese neonates |
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| Completed | N/A | 180 | | sevoflurane inhalation ;sevoflurane and fentanyl iv ;sevoflurane and caudal 0.2% levobupivacaine ;sevoflurane and 1mg/kg ketamine iv ;sevoflurane and caudal 0.2% levobupivacaine and 1ug/kg fentanyl ;sevoflurane and caudal 0.2% levobupivacaine and 0.5mg/kg ketamine | Guangzhou Women and Childrens Medical Center; None, self-financing | disease of newborn | | | | |
NCT02513433: Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural Anaesthesia |
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| Completed | N/A | 90 | RoW | Bupivacaine, Anawin, Sensorcaine, Levobupivacaine, Levo-anawin, Ropivacaine, Ropin | Government Medical College, Haldwani | Pain Insensitivity, Congenital | 08/14 | 09/14 | | |
NCT06763510: Comparison of the Effects of Two Different Local Anesthetics Used in Spinal Anesthesia |
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| Completed | N/A | 40 | RoW | Chirocaine, levobupivacaine, marcaine bupivacaine, bupivacaine | Ankara Ataturk Sanatorium Training and Research Hospital, Fatih University | Local Anaesthesia | 04/15 | 07/15 | | |
NCT02045810: Surgical Pleth Index- Relevance in Small Children |
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| Completed | N/A | 30 | Europe | Levobupivacaine, Saline | Tampere University Hospital | Anesthesia | 03/15 | 03/15 | | |
SiMuPort, NCT02556970: A Study Investigating Pain Following Single-port or Multi-port Video Assisted Thoracoscopic Surgery |
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| Withdrawn | N/A | 0 | Europe | Single port VATS, Paracetamol, Acetaminophen, Diclofenac, Voltarol, Camera (5mm diameter 30 degree videothoracoscope), Forceps grasper, 0.25% Levobupivicaine intercostal nerve block, 0.25% Chirocaine | University Hospitals Bristol and Weston NHS Foundation Trust, David Telling Charitable Trust | Pain, Postoperative | 09/15 | | | |
NCT02385539: Intrathecal Administration of Levobupivacaine and Opioids in Elderly |
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| Completed | N/A | 240 | RoW | The impact of 10 independent variables on the likelihood of not developing hypotension after intrathecal injection., levobupivacaine | Šarić, Jadranka Pavičić, M.D. | Adverse Reaction to Spinal Anesthetic | 09/15 | 09/16 | | |
US-SCB, NCT01624103: Comfort Score During Ultrasound Guided Supraclavicular Brachial Plexus Block Placement in Elderly Patients |
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| Unknown status | N/A | 50 | RoW | Upper limb surgery, Levobupivacaine, Lidocaine, Chirocaine, Xilocaine | Šarić, Jadranka Pavičić, M.D. | Arm Injuries, Wounds and Injuries | 11/15 | 11/15 | | |
| Unknown status | N/A | 70 | Europe | Injection of 0,2 ml/kg of 0,2% levobupivacaine for small volume group, Injection of 0,4 ml/kg of 0,1% lévobupivacaine for high volume group | University Hospital, Montpellier | Inguinal or Ovarian Hernia, Hydrocele, Cord Kyst, Local Analgesia Block, One to Five Years | 11/15 | 11/15 | | |
NCT02625506: Efficacy of Tramadol With Levobupivacaine for Modified Pectoral Nerve Block |
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| Completed | N/A | 60 | RoW | Levobupivacaine, Levobupivacaine and Tramadol | Mansoura University | Breast Cancer, Radical Mastectomy Surgery | 12/15 | 01/16 | | |
| Completed | N/A | 304 | Europe | Release analgesia by CADD SMITHS PCEA pump, Release analgesia by CADD SMITHS PIEB pump, Levobupivacaine, Sufentanil | University Hospital, Montpellier | Pregnancy | 12/15 | 06/16 | | |
AEDDATB, NCT02838719: Analgesic Efficacy of Dexamethasone in Different Routes of Administration in Transverse Abdominis Plane Block |
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| Completed | N/A | 40 | RoW | Perineural Dexamethasone acetate, Decoin, Intravenous dexamethasone acetate | Postgraduate Institute of Medical Education and Research | INFERTILITY | 12/15 | 12/15 | | |
ChiCTR-IOR-15006643: Analgesia with epidural dexmedetomidine in the phase of labor andthe risk of cesarean delivery |
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| Not yet recruiting | N/A | 2000 | | epidural dexmedetomidine ;epidural levobupivacaine and sufentanil | Department of Anesthesiology, Guangzhou Women andChildren Medical Center; Guangzhou Women and Children Medical Center, Departmental finance | nulliparous women in spontaneous labor or with spontaneous rupture of the membranes. | | | | |
NCT03856502: Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures |
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| Completed | N/A | 60 | RoW | 8 mg of dexamethasone, Dexamethasone KRKA, Chirocaine Abbott, 12,5 mg of 0,5 % of levobupivacaine, Chirocaine Abbott | General Hospital Sveti Duh | Femoral Fracture, Cognition Disorders, Cortisol; Hypersecretion | 05/16 | 07/17 | | |
NCT03337191: Ultrasound-Guided Versus Conventional Injection for Caudal Block |
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| Completed | N/A | 134 | RoW | Levobupivacaine, ultrasound guided caudal block, Morphine Sulfate, Ultrasound | Ataturk University | Ultrasound Therapy; Complications | 07/16 | 09/16 | | |
NCT02695654: Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis |
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| Completed | N/A | 77 | Europe | Levobupivacaine, Chirocaine, Clonidine, Catapresan | Mensur Salihovic | Knee Osteoarthritis | 08/16 | 08/16 | | |
ChiCTR-INd-16008256: Relation between range imaging and the skin analgesic distribution in costal margin transverse fascia block using different dosages of 0.25% levobupivacaine |
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| Not yet recruiting | N/A | 10 | | Volume | The Second Hospital affiliated to Wenzhou Medical College Yuying Children's Hospital; The Second Hospital affiliated to Wenzhou Medical College Yuying Children's Hospital, Funded by Health and family planning commission of zhejiang province in China | pain | | | | |
NCT02410746: Nerve Block Versus Non-targeted Local Anaesthesia in Breast Surgery |
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| Unknown status | N/A | 50 | Europe | targeted chirocaine pec block, Pectoral nerve block, standard chirocaine infiltration, intra-operative analgesia, standard post-operative analgesia, Morphine, Paracetamol, ibuprofen, analgesia | BMI Healthcare | Pain, Post Operative | 09/16 | 09/16 | | |
NCT02406300: Anesthesia And Post-operative Mortality After Proximal Femur Fractures |
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| Terminated | N/A | 57 | Europe | Subarachnoid Anesthesia, PNB/GA, ropivacaine, sevoflurane or desflurane, bupivacaine or levobupivacaine | Centro Hospitalar do Porto, Center for Health Technology and Services Research, Universidade do Porto | Hip Fractures | 12/16 | 12/16 | | |
| Completed | N/A | 55 | Europe | Paravertebral Thoracic block, Pectorals nerve block, Levobupivacaine 0.25%, Morphine | Istituti Ospitalieri di Cremona | Reconstruction Breast Surgery | 01/17 | 02/17 | | |
NCT02949661: Local Wound Infiltration for Tracheal Reconstruction |
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| Withdrawn | N/A | 0 | NA | Superficial cervical plexus block, Local wound infiltration | Mansoura University | Upper Tracheal Resection, Tracheal Reconstruction Surgery | 03/17 | 05/17 | | |
NCT02555423: The Effects of Serratus Plane Block Performed Under Direct Vision on Post-operative Pain in Breast Surgery |
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| Unknown status | N/A | | NA | Local anaesthetic - chirocaine | Kingston Hospital NHS Trust | Post-operative Pain, Serratus Block, Breast Surgery | 04/17 | | | |
NCT03110120: Interest of Serratus Plane Block in Postoperative Analgesia for Robot-assisted Surgery |
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| Completed | N/A | 60 | Europe | 0.5% levobupivacaine injectable solution with 10 ml of physiological saline, serratus plane block, local anesthesia, 0.5% levobupivacaine injectable solution with physiological saline, local serratus, local control | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Analgesia, Robotic Surgery | 06/17 | 06/17 | | |
NCT03302689: Comparison Levobupivacaine and Ropivacaine for TAP-block After Caesarean Section |
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| Unknown status | N/A | 50 | RoW | Levobupivacaine Solution, Levo, Ropivacaine Solution, Rop | Alexandr Ronenson | Pain, Postoperative | 10/17 | 01/18 | | |
NCT02737527: Comparison of the Efficacy of the Ultrasound With Fluoroscopy in Guidance of Lumbar Sympathetic Block |
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| Unknown status | N/A | 50 | RoW | 24G intravenous route for Lumbar Sympathetic Block (LSB):, lumbar sympathetic ganglion block (LSGB), lumbar sympathetic chain block, 15-cm Chiba needle for Lumbar Sympathetic Block (LSB), Ultrasound for Lumbar Sympathetic Block (LSB), Fluoroscope for Lumbar Sympathetic Block (LSB), 10 ml of 0.25% levobupivacaine injection for LSB, Temperature measurement for Lumbar Sympathetic Block (LSB), Postprocedure care for LSB | Seoul National University | Complex Regional Pain Syndrome, Postherpetic Neuralgia, Diabetic Polyneuropathy, Peripheral Neuropathy | 11/17 | 11/17 | | |
NCT03580980: Multimodal Analgesia in Major Abdominal Pediatric Cancer Surgeries |
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| Completed | N/A | 90 | RoW | Paracetamol and ketamine, Multimodal, Caudal levobupivacaine, Epidural, Morphine, Patient controlled analgesia | National Cancer Institute, Egypt | Pediatric Cancer, Pain, Postoperative | 11/17 | 11/17 | | |
NCT03785041: Preemptive and Postoperative Intra-articualr Injection of Levobupivacaine and Tramadol |
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| Completed | N/A | 220 | RoW | Levobupivacaine Hydrochloride 2.5 MG/ML, Tramadol 50 MG/ML, Tramadol 100 MG/ML, Levobupivacaine Hydrochloride 5MG/ML | Ain Shams University | Pain After Knee Arthroscop | 12/17 | 05/18 | | |
| Terminated | N/A | 671 | Europe | Programmed Intermittent bolus, PIEB, Manual epidural bolus, TOP-UP, Levobupivacaine, CHIROCAINE, Sufentanil 4 mcg, FENTATIENIL, Sufentanil 5 mcg | University of Modena and Reggio Emilia | Labor Pain | 12/17 | 02/18 | | |
NCT02726620: Decision Support for Intraoperative Low Blood Pressure |
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| Completed | N/A | 22435 | US | Attending real-time decision support, In-room real-time decision support, Attending feedback emails, In-room provider feedback emails, Anesthesia Information Management System (AIMS), Perioperative Data Warehouse (PDW), General anesthesia, Pager system, Central neuraxial anesthesia, Regional anesthesia, Spinal anesthesia, Intrathecal anesthesia, Subarachnoid anesthesia, Epidural anesthesia, Central neuraxial blockade, Non-cardiac surgery, Propofol, Sevoflurane, Desflurane, Isoflurane, Ephedrine, Phenylephrine, Norepinephrine, Epinephrine, Dobutamine, Dopamine, Isoproterenol, Milrinone, Atropine, Glycopyrrolate, Vasopressin, Terlipressin, Sodium Chloride 0.9%, Ringer's lactate, Hydroxyethyl starch solutions, Fresh Frozen Plasma, Packed Red Blood Cells, Albumin solutions, Plasma-Lyte, Lidocaine, Lignocaine, Bupivacaine, Levobupivacaine, Ropivacaine, Mepivacaine, Tetracaine, Prilocaine, Procaine, Chloroprocaine, Benzocaine, Articaine | Vanderbilt University Medical Center, UMC Utrecht | Hypotension | 12/17 | 12/18 | | |
ChiCTR1800017444: Effect of ropivacaine on uterine and abdominal muscle pushing power during the first and second stage of labor |
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| Completed | N/A | 161 | | 0.0625% ropivacaine for patient-controlled epidural analgesia (PCEA) ;0.0625% levobupivacaine for PCEA; no PCEA | Guangzhou Women and Children Medical Center; Guangzhou Women and Children Medical Center, This project was supported by the Natural Science Foundation of China (Grant no. 81701109 and 81671116). | labor analgesia | | | | |
NCT03426527: Dexmedetomidine for Bilateral Superficial Cervical Plexus Block for Reconstructive Tracheal Surgery |
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| Completed | N/A | 80 | RoW | Levobupivacaine, Levobupivacaine-Dexmedetomidine, General Anaesthesia | Mansoura University | Tracheal Reconstruction | 09/18 | 10/18 | | |
NCT03790163: The Effect of Different Degree of Temperature on Levobupivacaine Spinal Anesthesia |
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| Unknown status | N/A | 120 | RoW | Levobupivacaine, Chirocaine | Mansoura University Hospital | Spinal Anesthetic Toxicity | 03/19 | 04/19 | | |
NCT03754816: The Combination of PECS II Block and Parasternal Block for Radical Mastectomy |
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| Completed | N/A | 65 | Europe | PECS II and parasternal block, Pectoral nerve block II type and parasternal block, Levobupivacaine, Locali anesthetic | San Salvatore Hospital of L'Aquila | Breast Cancer | 03/19 | 04/19 | | |
NCT03592056: Hemidiaphragmatic Paralysis With Diluted Continuous Interscalene Plexus Infusions |
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| Terminated | N/A | 30 | RoW | | Clinica las Condes, Chile | Diaphragmatic Paralysis, Postoperative Pain, Acute Pain, Shoulder Pain, Shoulder Injury | 07/19 | 07/19 | | |
NCT03258697: The Pharmacokinetics and Effectiveness of Local LevoBupivacaine Injection on Primary Total Joint Replacement Model. |
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| Completed | N/A | 90 | RoW | Levobupivacaine Hydrochloride, Chirocaine | Chang Gung Memorial Hospital | Arthropathy | 01/19 | 05/19 | | |
| Unknown status | N/A | 150 | Europe | Levobupivacaine, Dexamethasone Sodium Phosphate, Placebos | The Adelaide and Meath Hospital, incorporating The National Children's Hospital | Pain, Postoperative, Ureter Stone | 12/19 | 12/19 | | |
NCT04325113: Post Tonsillectomy Analgesia Comparison After Surgery Site Spray of Local Anesthesics |
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| Completed | N/A | 44 | Europe | levobupivacaine, xylocaine, Nacl | University of Liege | Analgesia | 12/19 | 01/20 | | |
| Unknown status | N/A | 80 | RoW | INFRA ORBITAL BLOCK, Group L and Group R | All India Institute of Medical Sciences, Rishikesh | Pain, Postoperative | 01/20 | 03/20 | | |
NCT04729868: Ultrasound Guided Infraclavicular Brachial Plexus Block Using Levo-bupivacaine Alone or Combined With Dexmedetomidine for Hand and Forearm Surgeries |
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| Completed | N/A | 60 | RoW | Levobupivacaine(chirocaine) plus dexmedetomidine(precedex), the efficacy of levo-bupivacaine alone and with dexmedetomidine in Ultrasound guided infraclavicular brachial plexus block for hand and forearm surgeries | Aswan University Hospital | Acquired Deformity of Elbow, Forearm, Hand, Wrist | 04/20 | 10/20 | | |
NCT03433014: Local Wound Infiltration With 0.5% Levobupivacaine for Postoperative Pain After Laparoscopic Colorectal Surgery. |
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| Completed | N/A | 30 | RoW | 0.5% Levobupivacaine, Control | Mahidol University, Ramathibodi Hospital | Laparoscopic Colorectal Surgery, Colorectal Cancer | 08/20 | 12/20 | | |
NCT03815565: Continuous Femoral Block With Levobupivacaine 0.125% or Ropivacaine 0.2% in Elderly Patients With Femoral Fractures |
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| Unknown status | N/A | 70 | RoW | continuous femoral block | Hospital Municipal Miguel Couto | Femur Fracture, Hip Fractures | 08/20 | 01/21 | | |
NCT04284007: Intravenous Versus Perineural Effect Dexamethasone in Interscalene Nerve Block With Levobupivacaine |
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| Unknown status | N/A | 90 | RoW | Perineural levobupivacaine, Perineural dexamethasone in addition to levobupivacaine, Intravenous dexamethasone with perineural levobupivacaine | Mansoura University | Shoulder Pain | 11/20 | 12/20 | | |
NCT04467463: Peripheral Nerve Block Techniques During Cleft Palate |
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| Unknown status | N/A | 40 | RoW | peripheral nerve block by 0.25% levobupivacaine | Cairo University | Postoperative Pain | 12/20 | 12/20 | | |
QLBII, NCT03941899: The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type) |
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| Completed | N/A | 48 | Europe | Levobupivacaine in QLB II, Quadratus Lomborum Block II type | San Salvatore Hospital of L'Aquila | Postoperative Pain | 12/20 | 04/21 | | |
Levon, NCT06171295: Pharmacokinetics and Pharmacodynamics of Levobupivacaine During Continuous Caudal Epidural Analgesia in Newborns |
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| Completed | N/A | 24 | RoW | Blood draw | University Hospital, Motol | Analgesia | 07/22 | 07/22 | | |
| Recruiting | N/A | 250 | Europe | Levobupivacaine, Bupivacaine | Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele, Marinella Astuto | Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia | 04/21 | 09/21 | | |
| Recruiting | N/A | 90 | | dexmedetomidine and levobupivacaine sacral canal block ;Dexmedetomidine intranasal and levobupivacaine sacral canal block ;Levobupivacaine sacral block | Fujian Provincial Hospital; Fujian Provincial Hospital, self-raised | 4/5000 Pediatric hernia | | | | |
NCT05034406: The Effect of Subcutaneous and Intraperitoneal Anesthesia on Post Laparoscopic Pain |
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| Completed | N/A | 60 | RoW | 2% Lidocaine, 0.5% levobupivacaine | KBC Split | Varicocele, Postoperative Pain | 05/21 | 05/21 | | |
| Completed | N/A | 112 | RoW | Control Test, Neostigmine | Cairo University | Spermatic Cord Block | 11/23 | 12/23 | | |
NCT05617976: Nalbuphine as an Adjuvant to Levobupivacaine in Caudal Analgesia in Children |
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| Completed | N/A | 64 | RoW | caudal block | Ain Shams University | Caudal Anesthesia | 09/21 | 09/21 | | |
NCT05117281: Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children |
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| Completed | N/A | 60 | RoW | Levobupivacaine, Levobupivacaine hydrate, levobupivacaine hydrate | Assiut University | Pain, Postoperative, Analgesia | 10/21 | 10/21 | | |
NCT04773405: Minimum Effective Volume for Selective Trunk Block |
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| Completed | N/A | 25 | RoW | a 1: 1 mixture of 2% lidocaine with 5ug/ml epinephrine and 0.5% levobupivacaine, Selective trunk block | Chinese University of Hong Kong | Musculoskeletal Diseases or Conditions | 11/21 | 11/21 | | |
BvsLBvsHB, NCT05184465: Comparison of the Efficacy of 0.5% Bupivacaine, 0.5% Levobupivacaine, and 0.5% Hyperbaric Bupivacaine |
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| Completed | N/A | 111 | RoW | spinal anesthesia | Mogilev Regional Clinical Hospital | Anesthesia, Spinal | 01/22 | 01/22 | | |
NCT05447949: Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy |
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| Completed | N/A | 90 | RoW | Adjuncts to levobupivacaine in Erector Spinae Plane Block | National Cancer Institute, Egypt | Breast Cancer, Post Operative Pain | 03/22 | 03/22 | | |
NCT04531553: Erector Spinae Plane Block for Post-thoracotomy Pain Control |
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| Completed | N/A | 90 | RoW | Thoracic epidural analgesia, ESPB with levobupivacaine and dexmedetomedine, ESPB with levobupivacaine | National Cancer Institute, Egypt | Post-thoracotomy Pain Syndrome | 05/22 | 06/22 | | |
NCT06970548: Dexamethasone As Adjuvant for Pre - emptiveTransversusAbdominus Muscle Plane Block |
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| Completed | N/A | 40 | RoW | Levobupivacaine, Dexamethazone | Sohag University | Post Operative Pain | 05/23 | 06/23 | | |
NCT06970574: Comparative Study Between Intrathecal (Dexmedetomidine Versus Fentanyl) |
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| Completed | N/A | 60 | RoW | Levobupivacaine, fentanyl 50 mcg/ml, Dextmedetomidine | Sohag University | Cholecystitis | 07/23 | 07/23 | | |
NCT04152564: Cardio-pulmonary and Analgesic Effects of Pre-peritoneal VS Epidural Infusion of L-bupivacaine on Abd. Cancer Patients |
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| Completed | N/A | 60 | RoW | levo-bupivacaine infusion via Thoracic epidural catheter, TEA, levo-bupivacaine infusion via preperitoneal catheter | South Egypt Cancer Institute | Abdominal Cancer | 07/22 | 09/22 | | |
NCT04438265: Quadratus Lumborum Type 2 as Chronic Hip Pain Treatment |
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| Completed | N/A | 200 | Europe | levobupivacaine, chirocane, ultrasound device | Hospital Medina del Campo, Hospital Universitaio Getafe, Hospital Rio Hortega | Hip Arthropathy, Chronic Hip Pain, Ultrasound Therapy; Complications | 09/22 | 06/24 | | |
NCT03811262: Comparison of Erector Spinae Plane Block With PECS II Block in Patients Undergoing Breast Cancer Surgery |
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| Withdrawn | N/A | 0 | Europe | ESP BLOCK, PECS BLOCK, 30 ml 0.25% Levobupivacaine | University of Padova | Breast Cancer, Anesthesia, Local | 01/23 | 01/23 | | |
| Completed | N/A | 150 | Europe | Infiltration with NaCl, Infiltration with Ropivacain, Infiltration with a combination of Levobupivacaine and Tramadol | Balgrist University Hospital | Surgical Wound, Orthopedic Disorder of Spine | 01/23 | 03/23 | | |
NCT05728151: Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different Drugs |
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| Completed | N/A | 55 | RoW | Articaine and Epinephrine Only Product, levobupivacaine, mepivacaine | Research Institute of Ophthalmology, Egypt | Pediatric Squint Surgeries | 04/24 | 04/24 | | |
| Recruiting | N/A | 15 | Europe | Levobupivacaine, epidural catheter, invasive arterial catheter | Hospital Universitario La Fe | Hemodynamic Monitoring, Anesthesia; Adverse Effect, Pediatric Major Surgery, Epidural Analgesia | 04/23 | 09/23 | | |
NCT04431388: Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study |
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| Completed | N/A | 126 | Europe | ultrasound device, device, Levobupivacaine, drug | Hospital Medina del Campo | Kidney Injury | 06/23 | 12/23 | | |
DUAL, NCT05532618: Efficacy of Adductor Canal Block for Anterior Cruciate Ligament Surgery |
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| Completed | N/A | 34 | Europe | Adductor canal block, Levobupivacaine, Placebo | St. Antonius Hospital | Anterior Cruciate Ligament Injuries | 08/23 | 08/23 | | |
ChiCTR2300076523: Comparison of modified upper trunk block and traditional intermuscular groove block with bupivacaine liposomes in analgesia after shoulder arthroscopy |
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| Recruiting | N/A | 40 | | Bupivacaine liposomes 2.5ml+0.5% levobupivacaine 2.5ml will be injected between the three branches of the upper trunk; Bupivacaine liposome 7.5ml +0.5% levobupivacaine 7.5ml will be injected between the C5 and C6 nerve roots | the Second Affiliated Hospital & Yuying Children′s Hospital, Wenzhou Medical University; the Second Affiliated Hospital & Yuying Children′s Hospital, Wenzhou Medical University, self-raised | Rotator cuff injury | | | | |
NCT04735770: LTAP Block in Endometriosis Surgery - a Randomised Controlled Double-blind Trial |
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| Completed | N/A | 46 | Europe | Postoperative pain management: LTAP block or local wound anesthesia with levobupivacaine | Oulu University Hospital | Endometriosis; Peritoneum, Postoperative Pain | 12/23 | 12/23 | | |
NCT04908371: Selective Trunk Block vs Hybrid Interscalene Supraclavicular BPB for Anaesthesia of the Entire Upper Extremity |
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| Withdrawn | N/A | 110 | RoW | Selective Trunk Block, Drug (Xylocaine with adrenaline and Chirocaine), Interscalene-Supraclavicular Brachial Plexus Block (IS-SC BPB) | Chinese University of Hong Kong | Musculoskeletal Diseases or Conditions | 12/23 | 01/24 | | |
NCT06014957: Comparison of Hemodynamic Effect Between the Spinal Anesthesia and Saddle Block Using Levobupivacaine During Transurethral Resection of the Prostate in Cardiac Elderly Patients |
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| Recruiting | N/A | 60 | RoW | spinal anesthesia, saddle block | New Valley University | TURP Syndrome, Spinal Anesthesia | 12/23 | 12/23 | | |
PABLO, NCT04969133: TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children |
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| Completed | N/A | 110 | Europe | Levobupivacaine Hydrochloride 2.5 MG/ML | Centre Hospitalier Universitaire de Besancon | Appendicitis Acute, Pediatrics, Analgesia | 01/24 | 01/24 | | |
NCT05707169: Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein |
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| Active, not recruiting | N/A | 800 | RoW | Saphenous Ablation, Endogenous Laser Ablation (EVLA), mixture of 20 mL 2% lidocaine, 1: 200,000 adrenaline and 20 mL 0.5% levobupivacaine in 1 L of 0.9% saline | Mansoura University | Varicose Veins, Venous Reflux, Venous Insufficiency, Venous Leg Ulcer | 02/24 | 05/24 | | |
TAP ALIF, NCT06002217: Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF) |
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| Recruiting | N/A | 80 | Europe | Levobupivacaine, Placebo Tap block | Clinique Saint Jean, France | Fusion of Spine, Lumbar Region | 09/26 | 10/26 | | |
NCT07046052: PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture |
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| Recruiting | N/A | 150 | Europe | continuous infusion of levobupivacaine, Programmed Intermittent Bolus of Levobupivacaine | University College Cork | Hip Fracture, Analgesia Post Fracture | 01/26 | 01/26 | | |
NCT06410404: Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries |
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| Not yet recruiting | N/A | 60 | NA | transversus thoracis plane block, TTPB, Dexmedetomidine, Levobupivacaine | Assiut University | Pain, Postoperative | 06/25 | 07/25 | | |
NCT04941664: Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk Block |
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| Recruiting | N/A | 25 | RoW | 0.5% levobupivacaine, Peripheral nerve block | Chinese University of Hong Kong | Musculoskeletal Diseases or Conditions | 07/26 | 08/26 | | |
| Recruiting | N/A | 80 | Europe | Arthroscopic rotator cuff repair, naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA associated to GA), naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA) | Elsan | Shoulder Cuff Surgical Repair | 12/24 | 07/25 | | |
BESD-RCT, NCT06611176: Local LevoBupivacaine for Pain Relief After Endoscopic Submucosal Dissection for Esophageal Lesions |
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| Recruiting | N/A | 88 | Europe | Local levobupivacaine | Laura Boer | Endoscopic Submucosal Dissection, Levobupivacaine | 12/25 | 03/26 | | |
NCT04933266: Subpectoral Plexus Block With Multi-level TPVB for Surgical Anesthesia During Primary Breast Cancer Surgery |
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| Recruiting | N/A | 100 | RoW | Subpectoral plexus block (low dose), Drug (0.25% Chirocaine), Subpectoral plexus block (High dose) | Chinese University of Hong Kong | Breast Cancer | 03/26 | 03/26 | | |
ChiCTR2400086408: Comparison of the clinical application effect of epidural anesthesia with ultrasound-guided sacral anesthesia in anorectal surgery |
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| Recruiting | N/A | 160 | | Take the horizontal lateral decubitus position,an ultrasound linear probe is placed at the midline of the dorsal aspect of the patient's sacrum to obtain a cross-sectional ultrasound image, locate the sacrococcygeal ligament and sacral angle, and then insert the needle from between the two sacral angles to the sacral canal (performed by out-of-plane needle insertion technique).If there is no cerebrospinal fluid or blood in the respiration, 3mL of 2% lidocaine is injected into the supine position for 3 minutes, and if there are no signs of spinal anesthesia, 15mL of 0.5% levobupivacaine is injected horizontally on the lateral decubitus.; The patient was placed in the L3~4 space in the lateral decubitus position, and the epidural anesthesia was placed downward,after successful puncture, 3ml of 2% lidocaine was given, and the patient was observed in the supine position for 3 minutes, and if there were no signs of spinal anesthesia, 15ml of 0.5% levobupivacaine was injected in the horizontal lateral decubitus position. | Weihai Central Hospital; Weihai Central Hospital, Weihai Central Hospital | anorectal surgery | | | | |
NCT05840406: Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery |
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| Completed | N/A | 105 | RoW | Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine, Postoperative pain management with tramadol, Postoperative pain management with ketoprofen, Postoperative pain management with ibuprofen | University Hospital Sestre Milosrdnice | Postoperative Pain, Cesarean Section, Wound Heal | 03/25 | 03/25 | | |
NCT05816538: The Immune Response of Breast Cancer Patients Treated With Levobupivacaine Using Paravertebral or Superficial Chest Blocks |
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| Active, not recruiting | N/A | 100 | RoW | Paravertebral nerve block (PVB), Pectoralis and Serratus Plane Nerve Blocks (PECS 2), Regional anesthetic technique with ultrasound guidance, Regional anesthetic technique with peripheral nerve stimulation., Levobupivacaine 0.5%, General anesthesia | University of Rijeka | Paravertebral Block, Pectoralis and Serratus Plane Nerve Blocks, Breast Cancer, Immunologic Suppression, Levobupivacaine | 05/25 | 12/25 | | |