| Chirocaine (levobupivacaine) / Purdue, AbbVie |
NCT02430090: Comparison of Intratechal Levobupivacaine and Adding With Sufetanil and Fentanyl in Ceserean Section |
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| Completed | 2 | 45 | NA | Levobupivacaine, chirocaine, Fentanyl, Sufentanil, sufenta | Ankara City Hospital Bilkent | Anesthesia | 03/07 | 03/07 | | |
| Completed | 2 | 16 | Europe | placebo, levobupivacaine, ropivacaine, Intralipid® | Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France | Toxicity, Adverse Effects | 08/13 | 08/13 | | |
NCT01701778: Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children |
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| Completed | 2 | 90 | RoW | Caudal Dexmedetomidine, Precedex, Intravenous Dexmedetomidine, Placebo, Levobupivacaine, sevoflurane | Yao Yusheng, West China Hospital | Inguinal Hernia, Cryptorchidism | 01/14 | 01/14 | | |
| Completed | 2 | 80 | RoW | Dexamethasone, decadron, Levobupivacaine, chirocaine | ahmed elsakka | Effects of; Anesthesia, in Labor and Delivery | 09/15 | 10/15 | | |
2008-004471-22: Minimum local anesthetic concentration of levobupivacaine and clonidine given for caudal anesthesia in children |
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| Completed | 2 | 90 | Europe | CATAPRESAN, CATAPRESAN | ISTITUTO GIANNINA GASLINI | postoperative pain management | | | | |
NCT02665936: Effect of Epidural Dexamethasone on Labor Analgesia |
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| Unknown status | 2 | 90 | NA | Levobupivacaine, Dexamethasone and levobupivacaine, Levobupivacaine and Dexamethasone | Kasr El Aini Hospital | Labor | 02/16 | 02/16 | | |
2014-000682-50: A feasibility study investigating the clinical effectiveness and cost effectiveness of facet joint injections for low back pain against best usual care. |
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| Terminated | 2 | 150 | Europe | Levobupivacaine, Triamcinolone acetonide, Solution for injection/infusion, Suspension for injection, Levobupivacaine 5mg/ml, Adcortyl Intra-articular/Intradermal Injection 10mg/ml | University Hospitals Coventry and Warwickshire NHS Trust, University of Warwick, Research Support Services, , NIHR HTA | Facet Joint Pain, Low Back Pain, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2015-005247-14: Effect of levobupivacaine infiltration versus placebo on perineal postpartum pain in episiotomy of primiparous, after instrumental delivery. |
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| Completed | 2 | 330 | Europe | Solution for injection, Levobupivacaïne Fresenius Kabi | Centre Hospitalier Universitaire Brugmann, CHU Brugmann | Episiotomy (inclusion of primiparous patients giving birth by instrumental delivery -Suzor forceps, vacuum extraction, Thierry spatulas with episiotomy)., Episiotomy, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
NCT02848599: The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery |
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| Completed | 2 | 86 | RoW | morphine, levobupivacaine, Chirocaine | Osijek University Hospital | Postoperative Cognitive Dysfunction | 07/17 | 09/17 | | |
NCT02705872 / 2016-000889-35: Comparison of Two Methods of Administration of the Epidural, by Programmed Intermittent Bolus or Continuous Perfusion, on the Incidence of Cesarean Sections and Instrumented Deliveries in Primiparous Women |
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| Withdrawn | 2 | 0 | Europe | Chirocaine 0.07% + Sufentanil 0.3 mcg/ml 10ml/h, Chirocaine 0.07% + Sufentanil 0.3 mcg/ml 10ml each 60 minutes | Brugmann University Hospital | First Child Delivery With Epidural | 03/18 | 03/18 | | |
NCT02796547: Effect of Levobupivacaine Infiltration on the Post Partum Perineal Pain in Episiotomy, in Primiparous Women After Instrumental Delivery |
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| Withdrawn | 2 | 0 | Europe | Levobupivacaine, Physiological serum | Brugmann University Hospital | Episiotomy | 05/18 | 05/18 | | |
2016-003544-37: PERINEURAL LOCAL ANAESTHETIC CATHETER AFTER MAJOR LOWER LIMB AMPUTATION TRIAL |
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| Completed | 2 | 50 | Europe | Chirocaine, Solution for infusion, Chirocaine | Aneurin Bevan University Health Board, Research for Patient and Public Benefit (RfPPB), Health and Care Research Wales | Analgesia for lower limb amputation for peripheral vascular disease (PVD), Pain relief for lower leg amputation, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
NCT03549221: Efficacy of Adrenaline in Periarticular Analgesic Injection on Postoperative Pain Control After Total Knee Arthroplasty |
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| Unknown status | 2 | 82 | RoW | 0.6 mg 1:1000 epinephrine (0.6 ml), 100 mg Levobupivacaine (0.5%, 20 mL), 30 mg ketorolac (1 ml) | Mahidol University | Postoperative Pain | 10/18 | 10/18 | | |
NCT04178109: Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach. |
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| Completed | 2 | 226 | Europe | Dexketoprofen/tramadol (27mg/75mg), Tramadol hydrochloride, Paracetamol, Ropivacaine Hydrochloride 7.5 MG/ML, Levobupivacaine Hydrochloride | KAT General Hospital | Postoperative Pain, Pain, Acute | 11/19 | 11/19 | | |
| Completed | 2 | 72 | RoW | ACB group, IA group | Assiut University | Postoperative Pain | 07/23 | 07/23 | | |
NCT04275661: Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery |
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| Active, not recruiting | 2 | 60 | RoW | Ultrasound (US) bi-level erector spinae block, levobupivacaine, Ketamine, Magnesium Sulfate | Assiut University | Analgesia, Breast Cancer | 03/22 | 04/22 | | |
NCT06577155: Spinal Nalbuphine for Analgesia in Total Hip Arthroplasty |
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| Recruiting | 2 | 60 | Europe | Levobupivacaine, Levobupivacaine plus nalbuphine | Asklepieion Voulas General Hospital, Anastasios Mpontozis | Total Hip Arthroplasty, Analgesia | 05/25 | 06/25 | | |
ChiCTR2500109857: A single-center, randomized, double-blind, positive-controlled Phase II clinical study evaluating the preliminary efficacy, safety, and pharmacokinetic profile of levobupivacaine and 2-hydroxyethyl lidocaine aminium bromide injection (development code: LL10) for postoperative analgesia in patients undergoing elective surgery. |
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| Not yet recruiting | 2 | 50 | | Administration of intercostal nerve block with levobupivacaine hydrochloride injection (0.325%, 20 mL); Administration of intercostal nerve block with LL10 (1.258%/0.325%, 20mL); Administration of transversus abdominis plane block with levobupivacaine hydrochloride injection (0.188%, 80 mL); Administration of transversus abdominis plane block with LL10 (0.726%/0.188%, 80 mL); Administration of transversus abdominis plane block with LL10 (0.864%/0.223%, 80 mL) | West China Hospital, Sichuan University; West China Hospital of Sichuan University, Shangdong New Times Pharmaceutical Co., Ltd. | Postoperative pain | | | | |
NCT03778671: Dexmedetomidine Versus Fentanyl Added to Levobupivacaine for Transversus Abdominis Plane (TAP) Block |
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| Completed | 1/2 | 90 | RoW | Levobupivacaine, Levobupivacaine hydrate, Dexmedetomidine Injection [Precedex], fentanyl | Assiut University | Transversus Abdominis Block | 11/19 | 12/19 | | |
NCT04113720: Levobupivacaine vs Levobupivacaine + Dexmedetomidine Infiltration for Post-tonsillectomy Analgesia and Laryngospasm in Pediatric Patients |
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| Completed | 1/2 | 90 | RoW | Levobupivacaine hydrochloride, levobupivacaine, Levobupivacaine Hydrochloride + Dexmedetomidine, levobupivacaine + precedex | Assiut University | Post-tonsillectomy Analgesia, Levobupivacaine | 10/20 | 11/20 | | |