Sarcoma  >>  dactinomycin  >>  Phase 2
Welcome,         Profile    Billing    Logout  

16 Trials

Remove FilterRemove Filter

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
dactinomycin / Generic mfg.
NCT00003955: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Completed
2
77
Europe, Canada, US, RoW
dactinomycin, filgrastim, pegfilgrastim, sargramostim, cyclophosphamide, irinotecan hydrochloride, vincristine sulfate, radiation therapy
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
01/05
10/09
NCT00004250: Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery

Completed
2
35
US
dactinomycin, isolated limb perfusion, melphalan
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Melanoma (Skin), Sarcoma
06/07
 
NCT00084838: Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT

Completed
2
25
US
filgrastim, filgrastim XM02, G-CSF, cisplatin, CACP, cis-DDP, cis-diamminedichloro platinum (II), cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cismaplat, Platinol, cyclophosphamide, Ciclofosfamida, Ciclofosfamide, Claphene, CP monohydrate, CPM, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphanum, Cytophosphane, Mitoxan, Syklofosfamid, Zytoxan, Clafen, Cytoxan, Neosar, cytarabine, arabinofuranosylcytosine, arabinosylcytosine, aracytidine, beta-cytosine arabinoside, cytarabine hydrochloride, cytarabinum, cytosine arabinoside, cytosine arabinosine hydrochloride, Cytosar-U, Tarabine PFS, dexrazoxane hydrochloride, Totect, Zinecard, doxorubicin hydrochloride, Adriamycin PFS, Adriamycin RDF, etoposide, VP-16, leucovorin calcium, folinate calcium, folinic acid, methotrexate, temozolomide, Temodar, Methazolastone, Temodal, TMZ, CCRG-81045, therapeutic hydrocortisone, vincristine sulfate, leurocristine sulfate, Vincasar PFS, radiation therapy, Dactinomycin, ACT-D, actinomycin C1, actinomycin D, actinomycin I1, actinomycin IV, actinomycin X 1, actinomycin-[thr-val-pro-sar-meval], AD, dactinomycine, meractinomycin
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Central Nervous System Tumor, Pediatric
02/08
03/13
NCT00072280: Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Terminated
2
7
US, Canada, RoW
dactinomycin, DACT, Actinomycin-D, Cosmegen, NSC #3053, cyclophosphamide, Cytoxan, NSC #26271, etoposide, ETOP, VePesid, Etopophos, VP-16, NSC #141540, ifosfamide, Isophosphamide, Iphosphamide, Z4942, Ifex, NSC #109724, vincristine sulfate, Oncovin, VCR, LCR, NSC #67574, Conventional Surgery, MESNA (mercaptoethane sulfonate), Sodium 2-mercaptoethane sulfonate, UCB 3983, Mesnex, NSC #113891, Filgrastim, Granulocyte Colony-Stimulating Factor, r-metHuG-CSF, G-CSF, Neupogen, NSC #614629
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
03/08
03/08
NCT00025103: Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Unknown status
2
75
Europe
dactinomycin, carboplatin, cyclophosphamide, doxorubicin hydrochloride, etoposide, melphalan, vincristine sulfate, autologous bone marrow transplantation, conventional surgery, peripheral blood stem cell transplantation, radiation therapy
Children's Cancer and Leukaemia Group
Kidney Cancer
11/08
 
NCT00025441: Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Completed
2
Europe
dactinomycin, filgrastim, carboplatin, cyclophosphamide, doxorubicin hydrochloride, epirubicin hydrochloride, etoposide, ifosfamide, vincristine sulfate, peripheral blood stem cell transplantation, radiation therapy
Societe Internationale d'Oncologie Pediatrique, Children's Cancer and Leukaemia Group, Societe Francaise Oncologie Pediatrique
Ovarian Cancer, Sarcoma, Small Intestine Cancer
 
03/10
NCT00245141: Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma

Unknown status
2
32
Japan
dactinomycin, cyclophosphamide, vincristine sulfate, radiation therapy
Japan Rhabdomyosarcoma Study Group
Sarcoma
04/11
 
NCT00245089: Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma

Unknown status
2
41
Japan
dactinomycin, cyclophosphamide, vincristine sulfate
Japan Rhabdomyosarcoma Study Group
Sarcoma
04/11
 
NCT00541411: Phase II Pilot Study of Vincristine, Adriamycin, Actinomycin D, Ifosfamide Combination Chemotherapy in Ewing's Sarcoma

Unknown status
2
10
NA
Vincristine, Actinomycin-D, Ifosfamide
King Faisal Specialist Hospital & Research Center
Ewing's Sarcoma
06/13
06/13
AREN0321, NCT00335556: Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

Completed
2
291
US, Canada, RoW
Doxorubicin Hydrochloride, Irinotecan Hydrochloride, Conventional Surgery, surgery, conventional, Cyclophosphamide, Etoposide, Lastet, Carboplatin, Dactinomycin, Lyovac Cosmegen, Vincristine Sulfate, Kyocristine, Oncovin, VCR, Vincasar, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RT, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Childhood Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Clear Cell Sarcoma of the Kidney, Papillary Renal Cell Carcinoma, Rhabdoid Tumor of the Kidney, Stage I Renal Cell Cancer, Stage I Renal Wilms Tumor, Stage II Renal Cell Cancer, Stage II Renal Wilms Tumor, Stage III Renal Cell Cancer, Stage III Renal Wilms Tumor, Stage IV Renal Cell Cancer, Stage IV Renal Wilms Tumor
12/15
 
NCT01055314: Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Checkmark ASCO 2015
May 2015 - May 2015: ASCO 2015
Completed
2
175
US, Canada, RoW
Cixutumumab, Anti-IGF-1R Recombinant Monoclonal Antibody IMC-A12, IMC-A12, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, Dactinomycin, Actinomycin A IV, Actinomycin C1, ACTINOMYCIN D, Actinomycin I1, Actinomycin IV, Actinomycin X 1, Actinomycin-[thr-val-pro-sar-meval], Cosmegen, DACT, Dactinomycine, Lyovac Cosmegen, Meractinomycin, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16-213, VP-16, VP-16-213, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Irinotecan Hydrochloride, Campto, Camptosar, Camptothecin 11, Camptothecin-11, CPT 11, CPT-11, U-101440E, Laboratory Biomarker Analysis, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temodal, Temodar, Vincristine Sulfate Liposome, Marqibo
National Cancer Institute (NCI)
Adult Rhabdomyosarcoma, Childhood Alveolar Rhabdomyosarcoma, Childhood Embryonal Rhabdomyosarcoma, Metastatic Childhood Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma, Untreated Childhood Rhabdomyosarcoma
06/16
06/16
NCT04332874: A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

Recruiting
2
30
US
Isolated Limb Infusion, ILI, Pembrolizumab, infusion of melphalan and dactinomycin
Memorial Sloan Kettering Cancer Center
Sarcoma, Myxofibrosarcoma, Undifferentiated Pleomorphic Sarcoma, Alveolar Soft Part Sarcoma
04/25
04/25
RMS13, NCT01871766: Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active, not recruiting
2
98
US
Vincristine, Oncovin®, Dactinomycin, Actinomycin-D, Cosmegen®, Cyclophosphamide, Cytoxan(R), Surgical Resection, Surgery, Radiation, Proton Beam Radiation, External Beam Radiation, Brachytherapy, Bevacizumab, rhuMab, VEGF, Avastin®, Sorafenib, Nexavar®, Myeloid Growth Factor, G-CSF, Filgrastim, Pegfilgrastim, Lymph Node Sampling, Irinotecan, Camptosar ®, Ifosfamide, Ifex ®, Etoposide, VP-16, Vepesid®, Etoposide Phosphate, Etopophos®, Doxorubicin, Adriamycin®, Dexrazoxane, Zinecard, ^1^1C-methionine, Contrast Media
St. Jude Children's Research Hospital
Rhabdomyosarcoma
07/25
06/30
NCT04388839: Evolutionary Therapy for Rhabdomyosarcoma

Recruiting
2
28
US
Vincristine, Cyclophosphamide, Vinorelbine, Navelbine, Actinomycin D, Cosmegen, Cyclophosphamide Pill
H. Lee Moffitt Cancer Center and Research Institute, National Pediatric Cancer Foundation
Rhabdomyosarcoma
12/26
12/27
FaR-RMS, NCT04625907 / 2018-000515-24: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma

Recruiting
1/2
1672
Europe, RoW
Irinotecan, Actinomycin D, Dactinomycin, Doxorubicin, Ifosfamide, Vincristine, Vinorelbine, Cyclophosphamide, Temozolomide, radiotherapy, Regorafenib
University of Birmingham
Rhabdomyosarcoma
06/30
06/30
NCT06023641: Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Recruiting
1/2
100
US
Vincristine, Oncovin, Dactinomycin, (actinomycin-D), Cyclophosphamide, Cytoxan®., Surgical Resection, Proton beam radiation or external beam radiation or brachytherapy, Liposomal irinotecan, (Onivyde®), Vinorelbine, Navelbine, Temozolomide, Temodar, Filgrastim, peg-filgrastim, Neupogen
St. Jude Children's Research Hospital
Rhabdomyosarcoma
10/34
10/37

Download Options