Leukemia  >>  Farydak (panobinostat)  >>  Phase 1
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5 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Farydak (panobinostat) / Secura Bio
NCT01055483 / 2008-002986-30: A Phase Ib, Open-label, Multi-center Dose-finding Study of Oral Panobinostat (LBH589) in Combination With Ara-C and Mitoxantrone as Salvage Therapy for Refractory or Relapsed Acute Myeloid Leukemia

Completed
1
59
Europe
panobinostat/LBH589B
Novartis Pharmaceuticals
Acute Myeloid Leukemia
02/12
02/12
NCT01242774: Safety & Efficacy Study of Oral Panobinostat (LBH589) With Chemotherapy in Patients < 65 Years Old With Acute Myeloid Leukemia (AML)

Completed
1
46
Europe, US
Panobinostat, LBH589
Novartis Pharmaceuticals
Acute Myeloid Leukemia (AML)
05/14
05/14
NCT01613976: A Phase Ib Study of Panobinostat (LBH589) in Combination With 5-Azacitidine for Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML) Patients

Completed
1
10
Japan
Panobinostat, LBH589
Novartis Pharmaceuticals
Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), Acute Myeloid Leukemia (AML)
05/14
05/14
NCT01321346: A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

Completed
1
30
US
Panobinostat, LBH589, Cytarabine, Ara-C, cytosine arabinoside, Cytosar
Therapeutic Advances in Childhood Leukemia Consortium, Novartis
Lymphoblastic Leukemia, Acute, Childhood, Myelogenous Leukemia, Acute, Childhood, Hodgkin's Disease, Non-Hodgkin's Lymphoma
10/15
 
NCT01463046: Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

Completed
1
29
US
Panobinostat, LBH589, Cytarabine, ara-C, Daunorubicin, Cerubidine
University of California, San Francisco, Novartis
Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome
11/15
12/18

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