| losartan / Generic mfg. |
ACTRN12617001533381: Combination low dose blood pressure lowering treatment for patients with untreated hypertension |
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| Not yet recruiting | 4 | 12 | | | George Medicines, George Medicines (The George Institute) | Hypertension | | | | |
ACTRN12617001533381p: Combination low dose blood pressure lowering treatment for patients with untreated hypertension |
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| Not yet recruiting | 4 | 12 | | | George Medicines, George Medicines (The George Institute) | Hypertension | | | | |
ACTRN12619000861156: A comparison of drug metabolism in healthy volunteers and patients with severe chronic obstructive lung disease (COPD) |
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| Not yet recruiting | 4 | 24 | | | Dr Richard McNeill, Canterbury Medical Research Foundation | Chronic obstructive Pulmonary Disease (COPD), Drug metabolism | | | | |
ACTRN12619000861156p: A comparison of drug metabolism in healthy volunteers and patients with severe chronic obstructive lung disease (COPD) |
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| Not yet recruiting | 4 | 24 | | | Dr Richard McNeill, Canterbury Medical Research Foundation | Chronic obstructive Pulmonary Disease (COPD); Drug metabolism | | | | |
| Ongoing | 4 | 80 | Europe | Film-coated tablet, Losartan potassium, Perindopril Arginine | Monash Medical Centre , Monash University Health Practitioner Research Fellowship | The pharmacokinetics of oral creatine monohydrate (CrM) dosing in pregnancy, Metabolism of nutraceutical supplement (creatine monohydrate) in pregnancy | | | | |
ChiCTR-TRC-09000462: A randomized, controlled trial to evaluate the safety and efficacy of losartan in obvious proteinuria patients with lower-normal blood pressure |
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| Completed | 4 | 30 | | None ;Losartan 25-50mmHg | Renji Hospital of Shanghai Jiaotong University; Level of the institution：, self-funded | CKD with obvious proteinuria | | | | |
ChiCTR-TRC-09000426: Randomized controlled trial of losartan\propranolol in treating portal hypertension |
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| Completed | 4 | 90 | | Oral losartan by 25mg/d of the initial dose, three days latter alternate to 50mg/d ;Oral propranolol by 20mg/d of initial dose; then, progressively increase 10mg/d, max dose 120mg/d or rest heart rate reduced to the 75% of fundamental rate, or no less than 55/min ;Placebo | Department 1 of Infectious Diseases, 302 Hospital of P.L.A; Level of the institution：, self-finance | portal hypertension | | | | |
| Completed | 4 | 600 | | Levamlodipine Besylate ;Losartan | Endocrinology department, The Third Military Medical College, Southwest Hospital Chongqing; Endocrinology department, The Third Military Medical College, Southwest Hospital Chongqing, hospital administration funds | IFG and Hypertension | | | | |
ChiCTR-TRC-11001282: Triptolide Retards Autosomal Dominant Polycystic Kidney Disease with Proteinuria |
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| Completed | 4 | 60 | | Glucosidorum Tripterygll Totorum+losartan potassium ;Placebo + losartan potassium | Shanghai Changzheng Hospital; Science and Technology Commission of Shanghai, Shanghai Key Discipline Project.(No:B902) Shanghai Science and Technology Commission Major Research Project.(No:08dz1900601) | Autosomal dominant polycystic kidney disease | | | | |
ChiCTR-TRC-10000923: Therapeutic effect and safety of Huangkui Capsule for chronic kidney disease: a multi-center, randomized, open label study |
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| Completed | 4 | 420 | | Huangkui Capsule, 2.5g, tid，for 24 weeks ;Losartan, 50mg qd, for 24 weeks ;Huangkui Capsule, 2.5g, tid+ losartan 50mg qd, for 24 weeks | Chinese General Hospital of PLA; SZYY Group Pharmaceutical, SZYY Group Pharmaceutical Limited | chronic kidney disease | | | | |
ChiCTR-TRC-13003612: A Clinical Study of the Efficacy and Safety of Shenyankangfu Tablets in the Treatment of Primary Glomerulonephritis and Diabetic Kidney Disease |
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| Suspended | 4 | 720 | | shenyankangfu tablets + Losartan potassium tablets mimetic agent×2 ;shenyankangfu tablets mimetic agent +losartan potassium tablets 50mg +losartan potassium tablets mimetic agent ;shenyankangfu tablets mimetic agent +losartan potassium tablets 50mg×2 ;shenyankangfu tablets + Losartan potassium tablets 50mg+ losartan potassium tablets mimetic agent ;shenyankangfu tablets +losartan potassium tablets 50mg×2 | Chinese PLA General Hospital; Tianjin TongRenTang Group Co., Ltd., Enterprise Support | Primary Glomerulonephritis and Diabetic Kidney Disease | | | | |
2004-002020-17: ESTRATEGIAS PARA EL TRATAMIENTO DE LA HIPERTENSIÓN ARTERIAL. EVALUACIÓN DE UNA TERAPIA COMBINADA A DOSIS FIJAS (LOSARTÁN/HIDROCLOROTIAZIDA) vs MONOTERAPIA (ESTRATAAR).(STRATEGIES FOR THE TREATMENT OF ARTERIAL HYPERTENSION. ASSESSMENT OF A COMBINED THERAPY AT FIXED DOSES (LOSARTAN/HYDROCHOLOTHIAZIDE) vs MONOTHERAPY (ESTRATAAR) |
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| Ongoing | 4 | 140 | Europe | COZAAR PLUS (losartán / hydrochlorothiazide), COZAAR PLUS, COZAAR PLUS | Catalan Society of Family Medicine, represented by Dr Mariano de la Figuera Von Wichman and Gabriel | Stage II arterial Hypertension | | | | |
2009-010280-17: TS HYPE - Turner syndrome and Hypertension; a double-blinded randomised interventional trial. |
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| Ongoing | 4 | 40 | Europe | Cozaar, Carvedilol PCD, Cozaar, Carvedilol PCD | Organisation name was not entered | Turner syndrome, hypertension and aortopathy | | | | |
2007-006059-37: ENSAYO CLÍNICO PILOTO, ALEATORIZADO, CONTROLADO, PARALELO, DOBLE-CIEGO, PARA EVALUAR LA EFICACIA Y SEGURIDAD DE LOSARTÁN EN LA REDUCCIÓN DEL ESTRÉS OXIDATIVO Y LA DISMINUCIÓN DE LA TENSIÓN ARTERIAL (TA) EN PACIENTES CON SÍNDROME DE WILLIAMS (SW) Y DOS O MÁS COPIAS DEL GEN NCF1. |
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| Ongoing | 4 | 60 | Europe | COZAAR 50 mg comprimidos recubierto con pelicula, COZAAR 50 mg comprimidos recubierto con pelicula | Programa de Medicina Molecular y Genética, Hospital Vall d´Hebron | Pacientes con síndrome de Williams con evidencia molecular de microdeleción en 7q11.2. Edad: Niños de más de 5 años y adultos Sexo: ambos sexos estarán representados lo más paritariemente posible Variante molecular de la deleción que confirme la presencia de 2 o más copias del gen NCF1. | | | | |
2010-024175-58: Comparison of two treatment regimen of high blood pressure in patients with transplanted heart. |
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| Ongoing | 4 | 40 | Europe | perindopril, losartan, furosemid, metoprolol, amlodipin, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100 | IKEM, IKEM | Compensation of arterial hypertension in heart transplant recipients. Renal function and its changes in heart transplant recipients. | | | | |
| Ongoing | 4 | 1 | Europe | Losartan, | | Stiff skin syndrome | | | | |
2014-002524-27: The PALM-study (Placebo, Losartan, Low sodium & Moxonidine after PE) |
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| Ongoing | 4 | 30 | Europe | Losartankalium, Moxonidine, Losartankalium, Moxonidine | University Medical Center Utrecht, ZonMw | Post Partum Hypertension after preeclamptic pregnancy | | | | |
| Ongoing | 4 | 40 | Europe | losartan, N/A, Tablet | University of Oxford, MQ: Transforming Mental Health | DSM panic disorder, Panic disorder is a severe form of anxiety that is characterised by the occurence of intense panic attacks, without an apparent external reason., Psychiatry and Psychology [F] - Psychological processes [F02] | | | | |
ChiCTR-IPR-16008108: Songling Xuemaikang Capsule for primary hypertension with the control of Losartan potassium: a multi-center, randomized, double-blind controlled trial |
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| Recruiting | 4 | 640 | | Songling Xuemaikang capsule,the placebo of Losartan Potassium ;Losartan Potassium, the placebo of Songling Xuemaikang capsule | Dongzhimen hospital affiliated of Beijing University of Chinese Medicine; Shanghai Changzheng hospital; Dongzhimen hospital affiliated of Beijing University of Chinese Medicine, Pharmaceutical Co., Ltd. Chengdu Nakasone | Primary hypertension | | | | |
ChiCTR-IPR-16009366: Clinical trial for evaluation of the breviscapine affect to cytochrome P450 enzymes and transporter in healthy volunteers |
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| Recruiting | 4 | 18 | | 40mg po tid of placebo for two week, on the 15th day a single dose of fexofenadine120mg or midazolam 7.5mg or losartan potassium 50mg is given to volunteers ;40mg po tid of breviscapine for two week, on the 15th day a single dose of fexofenadine120mg or midazolam 7.5mg or losartan potassium 50mg is given to volunteers | College of Pharmacy and Chemistry, Dali University; College of Pharmacy and Chemistry, Dali University, Nation Natural Science Foundation of China | Healthy | | | | |
NCT05827484: The Effect of Combined Use of Anti-fibrotic Agent With Platelet Rich Plasma on Skeletal Muscle Healing After Acute Injuries |
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| Completed | 4 | 20 | NA | Autologous platelets rich plasma, PRP, Autologous platelets rich plasma + oral LOSARTAN administration, PRP + LOSARTAN | Mostafa Hassanein, Msc | PRP, Losartan, Muscle Injury, Sport Injury | 09/17 | 12/17 | | |
ChiCTR-IIR-17013487: A multicenter, double blind, double dummy, randomized controlled clinical study on the treatment of IgA nephropathy with Zhengqingfengtongning extantab |
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| Recruiting | 4 | 108 | | Zhengqing Fengtongning extantab ;Losartan Potassium Tablets ;Losartan Potassium Tablets + Zhengqing Fengtongning extantab | The Third Xiangya Hospital of Central South University; The Third Xiangya Hospital of Central South University, Major projects of Hunan provincial science and Technology Department、Hunan Zhengqing Pharmaceutical Group Co., Ltd. | IgA nephropathy | | | | |
2020-001595-15: Measures to slow the progression of chronic kidney disease in patients with protein in the urine and elevated potassium in the blood Et videnskabeligt forsøg med personer med kronisk nyresvigt og protein i urinen |
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| Not yet recruiting | 4 | 140 | Europe | Spironolactone, Losartan, Tablet, Oral powder in sachet, Coated tablet, Veltassa | Henrik Birn, Vifor Fresenius Medical Care Renal Pharma AG, Graduate School of Health Sciences, Aarhus University | Chronic kidney disease with albuminuria Kronisk nyresygdom med albuminuri, Chronic kidney disease with protein in the urine Kronisk nyresygdom med æggehvidestof i urinen, Not possible to specify | | | | |
2019-003141-15: Renohemodynamic Effects of Combined empagliflOzin and LosARtan |
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| Not yet recruiting | 4 | 24 | Europe | Empagliflozine, Losartan, Film-coated tablet, Jardiance, Cozaar | Amsterdam University Medical Center - location VU Medical Center, Boehringer Ingelheim | Diabetes Mellitus type 2, Diabetes, Diseases [C] - Hormonal diseases [C19] | | | | |
ChiCTR1900021113: Diabetic Kidney Disease with Qi and Yin Deficiency, Blood Stasis Syndrome Treated by Keluoxin Capsule Combined with Losartan Potassium: a randomized, double blinding, placebo controlled, multicenter clinical study |
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| Not yet recruiting | 4 | 252 | | Keluoxin Capsule+Losartan Potassium ;Placebo of Keluoxin Capsule + Losartan Potassium | Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences; Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Self-raising | Diabetic Kidney Disease | | | | |
ChiCTR1900023531: Efficacy and safety of Astragalus plus Notoginseng granule on type 2 diabetic nephropathy: the multi-centre randomized controlled trial |
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| Not yet recruiting | 4 | 100 | | losartan ;Astragalus plus Notoginseng granule combined losartan | Shanghai Sixth People's Hospital East; Shanghai Sixth People's Hospital East Campus, Shanghai municipal health and family planning commission | diabetic nephrology | | | | |
ChiCTR2000039934: The role of oral losartan in the prevention of acute mountain sickness: a randomized controlled trial |
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| Not yet recruiting | 4 | 200 | | oral Roxadustat capsules 50mg, BIW ;Oral placebo capsules,the same dosage as Oral Roxadustat | Western Theater Air Force Hospital; Western Theater Air Force Hospital, Western Theater Air Force Hospital | Acute altitude illness | | | | |
2021-001661-21: Feasibility of aggressively lowering urine albumin in individuals with kidney biopsy-proven diabetic kidney disease - A Pilot Study |
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| Not yet recruiting | 4 | 20 | Europe | Tablet, Injection, Forxiga, Jardiance, Ozempic, Telmisartan, Losartan, hydrochlorthiazide, Spironolactone, Trental, Olumiant, Kerendia, Rybelsus | Herlev and Gentofte Hospital, Herlev and Gentofte Hospital | Diabetic Kidney Disease, Kidney Disease due to diabetes mellitus type 2, Diseases [C] - Hormonal diseases [C19] | | | | |
| Recruiting | 4 | 50 | US | Sacubitril-Valsartan, Entresto, Usual care (standard-of-care) arm, Oral Vasodilator | The Cleveland Clinic | Stage D Heart Failure | 03/22 | 12/22 | | |
ChiCTR2000036108: Study on the safety and feasibility of losartan targeted therapy for pulmonary vein stenosis |
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| Not yet recruiting | 4 | 160 | | oral losartan ;Not taking losartan | Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine; Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai Shen Kang Hospital Development Center | Acquired pulmonary venous obstruction | | | | |
MRA-ACE, NCT03502031: Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy |
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| Recruiting | 4 | 72 | US | Renin-Angiotensin (RAAS) alone, Lispril, Enalapril, Perindopril, Losarta, Valsar etc.,, Renin-Angiotensin (RAAS) blockers in combination with Spironolactone, Lisinopril, Enalapril, Perindopril, Losartan, Valsartan, or Spironolactone | James A. Tumlin, MD, Nelson Kopyt, MD | Renal Insufficiency, Chronic, Diabetic Nephropathy Type 2 | 10/22 | 10/24 | | |
ChiCTR2000040391: Efficacy, safety and weight loss mechanism of pegylated losartan in obese patients with type 2 diabetes mellitus |
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| Not yet recruiting | 4 | 150 | | placebo ;Losenatide 100ug ;Losenatide 200ug ;Losenatide 300ug ;orlistat | The Second XIANGYA Hospital Of Central South University; The Second XIANGYA Hospital Of Central South University, Supported by China International Medical Exchange Foundation, Sumei China Diabetes Research Foundation in 2020 | obese patients with type 2 diabetes mellitus | | | | |
NCT06431477: Efficacy and Safety of Telmisartan Compared With Losartan |
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| Recruiting | 4 | 98 | RoW | telmisartan, Losartan | Chong Kun Dang Pharmaceutical | Diabetic Nephropathies, Hypertension | 10/25 | 10/25 | | |
NCT03692013: Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD) |
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| Not yet recruiting | 4 | 68 | NA | Losartan, Cozaar | Fifth Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University | Hypertension,Nephropathy | 06/23 | 12/23 | | |
ChiCTR2000035247: Clinical study of oral losartan application for the treatment of knee osteoarthritis: a randomized controlled trial. |
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| Not yet recruiting | 4 | 98 | | Oral losartan 50mg/ for 2 years ;Oral placebo 50mg/ for 2 years | Shenzhen Second People's Hospital; Shenzhen Second People's Hospital, Clinical Research Project of Shenzhen Second People's Hospital | osteoarthritis | | | | |
| Active, not recruiting | 4 | 2476 | US | High dose potent statin, atorvastatin or rosuvastatin, ACE-I (lisinopril) or ARB (losartan), ACE-I or ARB, Aspirin, Lifestyle Counseling, PACE Lifestyle Intervention, Quality of Life Questionnaires, QOL | University of Florida, United States Department of Defense | Coronary Artery Disease | 09/24 | 12/24 | | |
ChiCTR2000029417: Astragali Radix and Panax notoginseng combination for the treatment of diabetic nephropathy: clinical randomized controlled trial and mechanism study |
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| Recruiting | 4 | 106 | | Placebo combined with losartan ;Astragalus plus Notoginseng granule combined losartan | Shanghai Sixth People's Hospital; Shanghai Sixth People's Hospital, National Key R&D Program of China | diabetic nephrology | | | | |
NCT05402397: Losartan and Uric Acid Metabolism in Children With Proteinuric Nephropathies |
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| Recruiting | 4 | 40 | RoW | Losartan Potassium | Hospital General de Niños Pedro de Elizalde | Uric Acid Nephropathy | 12/23 | 07/24 | | |
PRISTINE, NCT05843162: A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome |
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| Not yet recruiting | 4 | 116 | NA | Telmisartan, Losartan | Chong Kun Dang Pharmaceutical | Essential Hypertension, Metabolic Syndrome | 12/23 | 12/23 | | |
CLIgAN, NCT04662723: Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy. |
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| Recruiting | 4 | 878 | Europe | Corticosteroid, Methylprednisolone succinate, prednisolone, Renin-angiotensin sytem blockers, Ramipril, lisinopril, losartan, Sodium-glucose cotransporter 2 inhibitor, dapagliflozin, canagliflozin, empagliflozin | Fondazione Schena, University of Bari | Glomerulonephritis, Immunoglobulin A Nephropathy | 06/24 | 12/26 | | |
NCT06333522: Losartan Use to Mitigate Arthrofibrosis Following Total Joint Arthroplasty |
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| Not yet recruiting | 4 | 240 | US | Losartan | NYU Langone Health | Arthrofibrosis of Knee | 01/26 | 01/26 | | |
NCT05157464: Losartan Use to Mitigate Arthrofibrosis Following Total Join Arthroplasty |
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| Withdrawn | 4 | 380 | US | Losartan | NYU Langone Health | Arthrofibrosis | 12/24 | 12/24 | | |
NCT02817360: NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients |
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| Recruiting | 4 | 2400 | Europe, RoW | RAS-antagonist and beta-blocker up-to maximal dosages, Enalapril 40mg/d, Ramipril 10mg/d, Lisinopril 40mg/d, Cilazapril 5mg/d, Perindopril 8mg/d, Captopril 150mg/d, Spirapril 24mg/d, Quinapril 40mg/d, Trandolapril 4mg/d, Zofenopril 60mg/d, Fosinopril 40mg/d, Candesartan 32mg/d, Valsartan 320mg/d, Irbesartan 300mg/d, Losartan 150mg/d, Eprosartan 800mg/d, Bisoprolol 10mg/d, Metoprololsuccinat 200mg/d, Carvedilol 50mg/d (100mg/d if weight is > 85kg), Nebivolol 10mg/d, RAS-antagonist and beta-blocker none or at stable dose | Martin Huelsmann | Heart Diseases, Diabetes Mellitus, Type 2 | 12/25 | 12/26 | | |
NCT04715568: Secondhand Tobacco Smoke and Cardiovascular Disease |
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| Recruiting | 4 | 100 | US | Losartan, Cozaar, Angiotensin II Receptor Blocker, Antihypertensive, Placebo, Inactive drug | University of California, San Francisco, Flight Attendant Medical Research Institute | Cardiovascular Diseases, Hypertension | 12/25 | 12/25 | | |
2013-002091-41: Research into the effect of the drug losartan in adult patients with a reduced function of the right cardiac chamber and a cardiac birth defect Onderzoek naar de werking van het medicijn losartan bij volwassen patienten met een verminderde functie van de rechter hartkamer en een aangeboren hartafwijking |
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| Ongoing | 3/4 | 120 | Europe | Losartan, Capsule, hard, Losartan | Academisch medisch centrum, ICIN | To study the effect of losartan in adult patients with Tetralogy of Fallot and right ventricular dysfunction, defined as right ventricular ejection fraction <50%. Without severe valvular lesions., Research into the effect of the drug losartan in patients with tetralogy of Fallot and decreased right heart chamber function, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2015-000239-34: A clinical study to investigate the use of commonly used heart failure medicines in the prevention of heart related illnesses in patients with diabetes mellitus but without heart disease. |
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| Ongoing | 3/4 | 2400 | Europe, RoW | Enalapril maleate, Ramipril, Lisinopril dihydrate, Perindopril arginine, Perindopril erbumine, Perindopril tert-butylamine, Captopril, Quinapril hydrochloride, Trandolapril, Fosinopril sodium, Candesartan cilextil, Valsartan, Irbesartan, Losartan potassium, Eprosartan mesilate, Bisoprolol fumerate, Carvedilol, Nebivilol hydrochloride, Not applicable, Tablet, , Capsule | Medizinische Universität Wien, Medical University of Vienna, Medizinische Universität Wien, | Type 2 diabetes mellitus, Type 2 diabetes, Diseases [C] - Hormonal diseases [C19] | | | | |
