| Intuniv (guanfacine XR) / Shionogi, Takeda |
NCT00151996: Safety and Tolerability of SPD503 and Psychostimulants in Children and Adolescents Aged 6-17 With Attention-Deficit/Hyperactivity Disorder (ADHD) |
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| Completed | 2 | 75 | NA | Methylphenidate + SPD503 (Guanfacine hydrochloride), Amphetamine + SPD503 | Shire | Attention Deficit Disorder With Hyperactivity | 12/04 | 12/04 | | |
NCT00150592: Safety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17 |
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| Completed | 2 | 182 | NA | SPD503 (Guanfacine HCl), Placebo | Shire | Attention Deficit Disorder With Hyperactivity | 10/05 | 10/05 | | |
NCT01470469: SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP) |
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| Completed | 2 | 83 | US | SPD503 (extended-release Guanfacine hydrochloride), Intuniv, Placebo | Shire | Generalized Anxiety Disorder (GAD), Anxiety, Separation, Phobia, Social | 07/13 | 07/13 | | |
| Completed | 2 | 5 | US | Guanfacine, Tenex, Intuniv | Yale University, National Institute on Drug Abuse (NIDA) | Smoking | 12/16 | 12/16 | | |
NCT02051309: Guanfacine Clinical Trial for Smoking Cessation |
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| Completed | 2 | 121 | US | Guanfacine, Intuniv, Placebo | Yale University, National Institute on Drug Abuse (NIDA) | Smoking Cessation | 11/20 | 11/20 | | |
NCT04198116: Combining Varenicline and Guanfacine for Smoking Cessation |
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| Recruiting | 2 | 140 | US | Varenicline, Chantix, Guanfacine ER, Intuniv | Yale University, National Institute on Drug Abuse (NIDA) | Smoking Cessation | 08/24 | 08/24 | | |
NCT03764098: Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders |
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| Recruiting | 2 | 160 | US | Guanfacine ER, Intuniv, Placebo | Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Use | 02/25 | 02/26 | | |
NCT05273567: A Trial of Guanfacine-er for Cannabis Use Disorder |
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| Active, not recruiting | 2 | 90 | US | guanfacine-ER, Intuniv-er, Placebo | New York State Psychiatric Institute, National Institute on Drug Abuse (NIDA) | Cannabis Use | 03/25 | 03/25 | | |
| Recruiting | 2 | 100 | RoW | Guanfacine Extended Release Oral Tablet, Intuniv, Guanfacine XR, Residential withdrawal, Engagement with alcohol and other drug services, Placebo | Orygen, Youth Support and Advocacy Service, University of Melbourne | Cannabis Use Disorder | 12/25 | 06/26 | | |
NCT03137082: Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD) |
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| Completed | 1/2 | 32 | US | Guanfacine XR 3mgs/daily, Intuniv, Placebo (for guanfacine), Sugar pill | Stony Brook University | Alcohol Abstinence | 03/21 | 03/21 | | |
