| tropisetron / Generic mfg. |
NCT00970450: The Central Analgesic Effects of Paracetamol on Serotonergic Pathways |
|
|
| Completed | N/A | 16 | Europe | Paracetamol, Tropisetron, Placebo | University Hospital, Basel, Switzerland | Analgesia | 03/10 | 04/10 | | |
| Completed | N/A | 157 | RoW | Transcutaneous electrical acupoint stimulation, TEAS, Electrical neuromuscular stimulation device,JNR-2, Sham transcutaneous electrical acupoint stimulation, Tropisetron, Tropisetron Hydrocloride Injection, Batch number:131001, Dexamethasone | Huashan Hospital | Postoperative Nausea and Vomiting | 12/14 | 01/15 | | |
| Unknown status | N/A | 130 | NA | Standard anti-emetics in conjunction with R-CHOP, R-CHOP:, rituximab, doxorubicin, vincristine, cyclophosphamide, prednisolone, Anti-emetics:, ondansetron, granisetron, tropisetron, palonosetron, metoclopramide, prochlorperazine, lorazepam, aprepitant | Australasian Leukaemia and Lymphoma Group, Merck Sharp & Dohme LLC | Lymphoma, Non-Hodgkin | 12/15 | 12/15 | | |
NCT02478047: Comparative Effect Study Between Distal-proximal Point Association and Local Distribution Point Association in Chemotherapy-induced Nausea and Vomiting |
|
|
| Unknown status | N/A | 240 | RoW | only antiemetic (Ramosetron, Tropisetron and dexamethasone), Matching points ST36+CV12 plus antiemetic drug, Matching points PC6+CV12 plus antiemetic drug, Matching points CV13+CV12 plus antiemetic drug | Tianjin University of Traditional Chinese Medicine, National Basic Research Program, China | Chemotherapy-induced Nausea and Vomiting | 06/16 | 09/16 | | |
ChiCTR-IPR-15007301: A randomized, open-label, pilot study: compairing the efficacy of aprepitant and metoclopramide for prevention of chemotherapy-induced delayed emesis in cancer patients receiving highly emetogenic chemotherapy |
|
|
| Not yet recruiting | N/A | 120 | | Day 1 palonosetron+dexamethasone+aprepitant, Day 2~4 dexamethasone+aprepitant ;Day 1 tropisetron+dexamethasone+aprepitant, Day 2~4 dexamethasone+aprepitant ;Day 1 palonosetron+dexamethasone, Day 2~4 dexamethasone ;Day 1 palonosetron+dexamethasone, Day 2~4 dexamethasone+metoclopramide | Guangzhou General Hospitol of Guangzhou Military Command PLA; Guangzhou General Hospitol of Guangzhou Military Command PLA, Self-funded | Chemotherapy-induced nausea andvomiting | | | | |
NCT02625181: Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis |
|
|
| Completed | N/A | 27034 | US | Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email, Automated notification at the end of surgery, Anesthesia Information Management System (AIMS), Perioperative Data Warehouse (PDW), General anesthesia, Elective surgery, Propofol, Sevoflurane, Isoflurane, Desflurane, Scopolamine, Droperidol, Haloperidol, Dexamethasone, Promethazine, Meclizine, Aprepitant, Metoclopramide, Fentanyl, Sufentanil, Alfentanil, Remifentanil, Morphine, Meperidine, Hydromorphone, Methadone, Oxycodone, Oxymorphone, Hydrocodone, Ketamine, Ondansetron, Granisetron, Dolasetron mesylate, Palonosetron, Tropisetron, Ramosetron | Vanderbilt University | Postoperative Nausea and Vomiting | 11/17 | 11/17 | | |
ChiCTR-IOR-15006651: Prevention and treatment of low-dose naloxone on perioperative opioid-induced hyperalgesia |
|
|
| Recruiting | N/A | 360 | | Induction of anesthesia: Remifentanil, sevoflurane, cisatracurium, Postoperative analgesia with sufentanil, tropisetron ;Induction of anesthesia: Remifentanil, sevoflurane, cisatracurium, low-dose naloxone, Postoperative analgesia with sufentanil, tropisetron, low-dose naloxone ;Induction of anesthesia: Remifentanil, sevoflurane, cisatracurium, Maintenance of anesthesia: Remifentanil, sevoflurane, Postoperative analgesia with fentanil, tropisetron ;Induction of anesthesia: Remifentanil, sevoflurane, cisatracurium, low-dose naloxone, Maintenance of anesthesia: Remifentanil, sevoflurane, low-dose naloxone, Postoperative analgesia with fentanil, tropisetron, low-dose naloxone ;After the success of subarachnoid block, continuous intravenous infusion of remifentanil. Postoperative analgesia with sufentanil, tropisetron. ;After the success of subarachnoid block, continuous intravenous infusion of remifentanil and low-dose naloxone. Postoperative analgesia with sufentanil, tropisetron, low-dose naloxone. | Beijing Military General Hospital; Level of the institution：, Supported by Beijing Municipal Science & Technology Commission | hyperalgesia | | | | |
ChiCTR1900021396: A randomized controlled trial for western medicine combined with traditional Chinese medicine in the treatment of nausea and vomiting during and after cesarean section |
|
|
| Completed | N/A | 173 | | Acupuncture + Drugs ;Acupuncture + Normal saline ;Drugs+False acupuncture ;Normal saline+False acupuncture | Cangzhou Central Hospital; Cangzhou Central Hospital, Providing by department | Nausea and vomiting | | | | |
ChiCTR1800016788: Postoperative infusion of dexmedetomidine for prevention of postoperative delirium in elderly patients after non-cardiac surgery |
|
|
| Recruiting | N/A | 556 | | patient-controlled intravenous analgesia: sufentanyl 2μg/kg, dexmedetomidine 0.1μg/kg/h, tropisetron 6mg to 100ml ;patient-controlled intravenous analgesia: sufentanyl 2μg/kg, tropisetron 6mg to 100ml | Xuzhou Medical University Affiliated Hospital; Xuzhou Medical University Affiliated Hospital, self-finance | postoperative delirium | | | | |
ChiCTR1800017589: A study on acupoint application of ginger and tangerine warm-stomach cream combined with tropisetron and dexamethasone in the prevention and treatment of Chemotherapy Induced Nausea and Vomiting |
|
|
| Not yet recruiting | N/A | 288 | | Phase I: ginger and tangerine warm-stomach cream tropisetronon; Phase II: blank ;Phase I: blank, Phase II: ginger and tangerine warm-stomach cream tropisetronon | The First College of Clinical Medicine, Guangzhou University of Chinese Medicine; The First College of Clinical Medicine, Guangzhou University of Chinese Medicine, self-financed | colorectal cancer | | | | |
ChiCTR-INR-17010779: Efficacy and safety of the first generation of 5-HT3 receptor antagonist compare with the second generation of 5-HT3 receptor antagonists in preventing multiday-based highly emetogenic chemotherapy-induced nausea and vomiting： a randomized, open, cross-over control, multi-center study |
|
|
| Not yet recruiting | N/A | 300 | | Treat by A regimen (palonosetron 0.25mg*d1, d3+dexamethasone 10mg*d1, 5mg*d2-5) in the first cycle; then treat by B regimen (tropisetron 5mg*d1-3/5+dexamethasone 10mg*d1, 5mg*d2-5) in the second cycle ;Treat by B regimen (tropisetron 5mg*d1-3/5+dexamethasone 10mg*d1, 5mg*d2-5) in the first cycle; then treat by A regimen (palonosetron 0.25mg*d1, d3+dexamethasone 10mg*d1, 5mg*d2-5) in the second cycle | The Affiliated Tumor Hospital of Guangxi Medical University; The Affiliated Tumor Hospital of Guangxi Medical University, Guangxi science and technology development plan (1598012-24); Appropriate technology for health care research and development projects in Guangxi (S201509) | chemotherapy-induced nausea and vomiting | | | | |
ChiCTR1800018486: Effect of Acupoint injection on preventing nausea and vomiting after Gynecological Laparoscopic surgery |
|
|
| Recruiting | N/A | 600 | | navoban 5mg intravenous injection and dexamethasone 5mg intravenous infusion ;navoban 5mg intravenous injection and dexamethasone 5mg acupoint injection ;navoban 5mg intravenous injection and saline 1ml acupoint injection ;navoban 5mg intravenous injection and simple acupoint stimulation ;navoban 5mg intravenous injection and dexamethasone 5mg 2cm injection beside acupoint | Shaanxi Province Tumor Hospital; Shaanxi Province Tumor Hospital, own expense | nausea and vomiting after surgery | | | | |
ChiCTR2100041682: Effect of accurate multimodal analgesia on postoperative analgesia and quality of life in patients undergoing video-assisted thoracoscopic surgery |
|
|
| Recruiting | N/A | 180 | | Spray tazoxin 60mg + dexamethasone 5mg + tropisetron hydrochloride for injection 10 mg+ normal saline, total 100mL ;Spray tazoxin 60mg + dexamethasone 5mg + tropisetron hydrochloride for injection 10 mg+ normal saline, total 100mL ;On the basis of patient-controlled intravenous analgesia, anterior serratus muscle block was performed with 0.375% ropivacaine 30ml, and the block level was at T2~T6. ;On the basis of patient-controlled intravenous analgesia, combined with 0.5% ropivacaine local incision infiltration | Affiliated Hospital of Jiangnan University; Level of the institution：, Wuxi Taihu Lake Talent Plan 2020 (double hundred) Top Talent Project (BJ2020049) | Postoperative analgesia | | | | |
ChiCTR2100042109: Clinical randomized controlled trial of multimodal analgesia (MMA) and patient controlled analgesia (PCA) in Oblique Lumbar Interbody Fusion |
|
|
| Recruiting | N/A | 50 | | 1 hour before induction of anesthesia, oral celecoxib capsules 200 mg, pregabalin capsules 150 mg；Before the end of the operation, use ropivacaine injection 20ml: 150mg for local infiltration anesthesia at the operating area or screw entry site；After the patient was awake from anesthesia, he was intravenously infus ;After the patient is awake from anesthesia, a patient-controlled analgesia pump is placed intravenously, prepared with 100ug sufentanil citrate, 10mg tropisetron hydrochloride injection, and 20mg dezocine injection (loading volume 2ml + continuous dose 2ml/h + self-controlled analgesia The pump dose is 0.5ml/time, the lock | Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine; Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine, The equipment and materials needed for the research will be provided by the hospital of traditional Chinese medicine of xinjiang uygur autonomous region | Lumbar degenerative disease | | | | |
ChiCTR2000034724: Effect of remifentanil combined with dexmedetomidine on postoperative sleep quality in patients undergoing thoracoscopic lobectomy |
|
|
| Not yet recruiting | N/A | 76 | | Application of Sufentanil combined with dexmedetomidine and tropisetron for postoperative patient-controlled analgesia ;Application of remifentanil combined with dexmedetomidine and tropisetron for postoperative patient-controlled analgesia | Affiliated Hospital of Xuzhou Medical University; Level of the institution：, Affiliated Hospital of Xuzhou Medical University | Sleep disorders after thoracoscopic lobectomy | | | | |
ChiCTR2100044641: The analgesic effect of ultrasound-guided transversus abdominis plane block combined with PCIA after cesarean section: a randomized controlled trial |
|
|
| Recruiting | N/A | 102 | | ultrasound-guided transversus abdominis plane block (0.375% ropivacaine 20ml on each side） combined with PCIA（butorphanol 3.5ug/kg/h ，flurbiprofen axetil 83 ug/kg/h+Tropisetron mesylate13.33mg) ;sufentanil 150ug, tropisetron mesylate 13.33mg ;morphine 8mg, ropivacaine 135mg | Guangdong Second Provincial General Hospital; Guangdong Second Provincial General Hospital, Youth Fund Projects of Guangdong Second Provincial General Hospital | Cesarean section | | | | |
ChiCTR2000033977: Clinical study of nalbuphine combined with sufentanil PCIA for postoperative analgesia in patients undergoing abdominal surgery |
|
|
| Recruiting | N/A | 1320 | | Nalbuphine 0.5mg/ml + sufentanil 0.5μg/ml + tropisetron 5mg ;Sufentanil 1μg/ml + tropisetron 5mg | Qingdao Municipal Hospital; Qingdao Municipal Hospital, Self-raised | Issues related to analgesia after abdominal surgery | | | | |
ChiCTR2200066599: Effect of Gronium bromide injection on preventing nausea and vomiting in gynecological laparoscopic surgery |
|
|
| Not yet recruiting | N/A | 114 | | Gelomonium 0.2 mg and Tropisetron 5 mg ;Tropisetron 5 mg | Qianjiang Hospital Affiliated to Chongqing University ; Qianjiang Hospital Affiliated to Chongqing University, Qianjiang Hospital Affiliated to Chongqing University | Anesthesia with nausea and vomiting | | | | |
ChiCTR2100043226: Prospective study of different postoperative analgesia regimens and patients' recovery quality |
|
|
| Recruiting | N/A | 300 | | Fentanyl 15ug/kg+ tolisetron 10mg ;Butorphanol 0.15mg/kg+ Tropisetron 10mg ;Fentanyl 7.5ug/kg+ butorphanol 0.075mg/kg+ tolisetron 10mg | The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, Special Fund for Clinical Exploration of Static Analgesia in Guizhou, Yunnan Town | Gastrointestinal tract and thoracic tumors | | | | |
ChiCTR2200064069: Effect of different methods of auricular point stimulation on chemotherapy-induced nausea and vomiting and appetite in patients receiving platinum-based chemotherapy |
|
|
| Recruiting | N/A | 96 | | Routine nursing and intravenous drip of tropisetron hydrochloride injection ;The method of Control group and Auricular Pressing Beans ;The method of Control group and Auricular acupuncture | Affiliated Hospital of Nanjing University of Chinese Medicine; Affiliated Hospital of Nanjing University of Chinese Medicine, Project of Jiangsu Graduate Research and Practice Innovation Program | chemotherapy-induced nausea and vomiting | | | | |
ChiCTR2200056551: Application of opioid free-patient control analgesia in thoracic endoscopic surgery |
|
|
| Not yet recruiting | N/A | 90 | | Esketamine, dexmedetomidine and tropisetron ;Sufentanil, dexmedetomidine and tropisetron ;Dexmedetomidine, tramadol and tropisetron | The Second Affiliated Hospital of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, None | N/A | | | | |
ChiCTR2300071833: Clinical study on the effect of buccal acupuncture combined with tropisetron on the prevention of nausea and vomiting after gynecological laparoscopic surgery |
|
|
| Not yet recruiting | N/A | 60 | | Buccal acupuncture combined with tropisetron ;Tropisetron alone was applied | The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, Department of Anesthesiology, the First Affiliated Hospital of China Medical University | Postoperative nausea and vomiting | | | | |
ChiCTR2300070106: Application of Esketamine combined with dexmedetomidine in postoperative analgesia after traditional open thyroid surgery |
|
|
| Not yet recruiting | N/A | 120 | | Sufentanil+dexmedetomidine+tropisetron ;Dextrmetomidine+tramadol+tropisetron ;Esketamine+dexmedetomidine+tropisetron | Department of Anesthesiology, the Second Affiliated Hospital of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, no | Open thyroid surgery | | | | |
