| Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie |
NCT01499290 / 2011-003893-97: Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections |
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| Completed | 3 | 493 | US, Europe, RoW | CAZ-AVI, Metronidazole, Meropenem | Pfizer, Forest Laboratories | Complicated Intra-Abdominal Infection | 04/14 | 04/14 | | |
NCT01595438 / 2011-005721-43: Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) |
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| Completed | 3 | 598 | Japan, US, Europe, RoW | Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral), or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral) | Pfizer, Forest Laboratories | Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis | 08/14 | 08/14 | | |
NCT01599806 / 2011-005722-21: Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) |
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| Completed | 3 | 641 | US, Europe, RoW | Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral), or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral) | Pfizer, Forest Laboratories | Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis | 08/14 | 08/14 | | |
| Completed | 3 | 345 | US, Europe, RoW | Ceftazidime - Avibactam ( CAZ-AVI), Best Available Therapy, Metronidazole, Flagyl | Pfizer, Forest Laboratories | Complicated Urinary Tract Infection, Complicated Intra-abdominal Infection | 09/14 | 09/14 | | |
RECLAIM3, NCT01726023: Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd Infections |
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| Completed | 3 | 486 | RoW | Ceftazidime-avibactam, metronidazole, Meropenem | Pfizer | Complicated Intra-abdominal Infection | 03/15 | 03/15 | | |
| Completed | 3 | 969 | Japan, Europe, RoW | ceftazidim-avibactam (CAZ-AVI, experimental product), meropenem (active comparator) | Pfizer | Nosocomial Pneumonia (NP), Ventilator-associated Pneumonia (VAP) | 01/16 | 01/16 | | |
NCT04927312: Study to Assess Efficacy and Safety of PF-06947386 in Japanese Adult Patients With Complicated Intra-abdominal Infection |
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| Completed | 3 | 60 | Japan | PF-06947386, Metronidazole | Pfizer | Complicated Intra-abdominal Infection | 09/22 | 09/22 | | |
