| hydrochlorothiazide / Generic mfg. |
NCT00649597: Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg |
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| Completed | 1 | 56 | US | Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg, Lotensin HCT® Tablets 20 mg/25 mg | Mylan Pharmaceuticals Inc | Healthy | 12/02 | 12/02 | | |
NCT00649038: Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg |
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| Completed | 1 | 24 | US | Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg, Lotensin HCT® Tablets 20 mg/25 mg | Mylan Pharmaceuticals Inc | Healthy | 12/02 | 12/02 | | |
NCT00649233: Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg |
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| Completed | 1 | 32 | US | Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg, Lopressor HCT® Tablets 100/50 mg | Mylan Pharmaceuticals Inc | Healthy | 02/03 | 02/03 | | |
NCT00649688: Fasting Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg and Lopressor HCT® Tablets 100/50 mg |
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| Completed | 1 | 32 | US | Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg, Lopressor HCT® Tablets 100/50 mg | Mylan Pharmaceuticals Inc | Healthy | 02/03 | 02/03 | | |
NCT00648011: Food Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg |
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| Completed | 1 | 44 | US | Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg, Accuretic™ Tablets 20 mg/25 mg | Mylan Pharmaceuticals Inc | Healthy | 08/03 | 09/03 | | |
NCT00649441: Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg |
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| Completed | 1 | 60 | US | Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg, Accuretic™ Tablets 20 mg/25 mg | Mylan Pharmaceuticals Inc | Healthy | 09/03 | 09/03 | | |
NCT00834067: Moexipril HCl/Hydrochlorothiazide 15/25 mg Tablets Under Non-Fasting Conditions |
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| Completed | 1 | 60 | US | Moexipril HCl/hydrochlorothiazide 15/25 mg tablets, UNIRETIC® 15/25 mg tablets | Teva Pharmaceuticals USA | Healthy | 11/03 | 11/03 | | |
NCT00835042: Moexipril HCL/Hydrochlorothiazide 15/25 mg Tablets Under Fasting Conditions |
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| Completed | 1 | 60 | US | Moexipril HCl/hydrochlorothiazide 15/25 mg tablets, UNIRETIC® 15/25 mg tablets | Teva Pharmaceuticals USA | Healthy | 11/03 | 11/03 | | |
NCT00649324: Fasting Study of Hydrochlorothiazide Tablets 50 mg to Hydrochlorothiazide Tablets 50 mg |
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| Completed | 1 | 40 | US | Hydrochlorothiazide Tablets 50 mg, Hydrochlorothiazide Tablets (50 mg | Mylan Pharmaceuticals Inc | Healthy | 10/05 | 10/05 | | |
NCT00671424: A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide |
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| Completed | 1 | 48 | US | Hydrochlorothiazide (HCTZ), Remogliflozin etabonate (GSK189075), Furosemide | GlaxoSmithKline | Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2 | 05/08 | 05/08 | | |
NCT00923533: A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male Volunteers |
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| Completed | 1 | 34 | RoW | Fimasartan, Hydrochlorothiazide | Boryung Pharmaceutical Co., Ltd | Essential Hypertension | 05/09 | 08/09 | | |
NCT00871871: Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed) |
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| Completed | 1 | 64 | RoW | Hydrochlorothiazide (HCTZ), HCTZ, Comparator: Placebo to HCTZ, Isosorbide mononitrate (ISMN), Comparator: Placebo to ISMN | Merck Sharp & Dohme LLC | Hypertension | 02/10 | 03/10 | | |
NCT01276288: Pharmacodynamics and Pharmacokinetics of Empagliflozin and Torasemide in Patients With Type 2 Diabetes |
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| Completed | 1 | 23 | Europe | BI 10773, hydrochlorothiazide, torasemide | Boehringer Ingelheim | Diabetes Mellitus, Type 2 | 06/11 | | | |
NCT02962336: Bioequivalence Study of Torrent's Olmesartan Medoxomil, Amlodipine and Hydrochloride Tablets Under Fasting Conditions. |
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| Completed | 1 | 34 | US | Torrent's Olmesartan medoxomil, Amlodipine and Hydrochlorothiazide Tablets, Tribenzor Tablets of Daichi Sankyo Inc, USA | Torrent Pharmaceuticals Limited | Healthy Subjects | 06/11 | 06/11 | | |
NCT02962258: BE Study of Torrent's Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Tab - Fed Conditions |
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| Completed | 1 | 34 | US | Torrent's Olmesartaan medoxomil, Amlodipine and Hydrochlorothiazide Tablets, Tribenzor of Daichi Sankyo Inc. USA | Torrent Pharmaceuticals Limited | Healthy Subjects | 06/11 | 06/11 | | |
NCT01294631: A Pharmacodynamics, Pharmacokinetics, and Safety Study of Hydrochlorothiazide and Canagliflozin in Healthy Volunteers |
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| Completed | 1 | 30 | US | Canagliflozin 300 mg once daily and HCTZ 25 mg once daily | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Healthy | 07/11 | 07/11 | | |
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NCT01370655: A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009) |
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| Completed | 1 | 46 | NA | MK-7145, Hydrochlorothiazide (HCTZ), Placebo to MK-7145, Placebo to HCTZ | Merck Sharp & Dohme LLC | Hypertension | 12/11 | 01/12 | | |
NCT01827878: Bioequivalence Study of Lisinopril and Hydrochlorothiazide Tablets (20+25) mg Under Fed Conditions |
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| Completed | 1 | 48 | RoW | Lisinopril and Hydrochlorothiazide Tablets (20+25) mg, Test product, Zestoretic® 20/25 lisinopril/hydrochlorothiazide Tablets, Reference product | IPCA Laboratories Ltd. | Fed | 10/12 | 10/12 | | |
NCT01831700: Bioequivalence Study of Lisinopril and Hydrochlorothiazide Tablets (20+25) mg Under Fasting Conditions |
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| Completed | 1 | 48 | RoW | Lisinopril and Hydrochlorothiazide Tablets (20+25) mg, Test product, Zestoretic® 20/25 lisinopril/hydrochlorothiazide Tablets, Reference product | IPCA Laboratories Ltd. | Fasting | 10/12 | 10/12 | | |
NCT00990301: A Study to Compare the Relative Bioavailability of Moexipril HCl/Hydrochlorothiazide in Healthy Adult Volunteers Under Fasting Conditions |
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| Completed | 1 | 48 | US | Moexipril HCl/ Hydrochlorothiazide 15mg/ 25mg Tablet, Paddock Laboratories, Inc., Uniretic® 15mg/25mg Tablets | Paddock Laboratories, Inc. | Healthy | | | | |
NCT02094924: A Relative Bioavailability Study of a Fixed Dose Combination (FDC) Tablets of GSK587323 |
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| Completed | 1 | 16 | RoW | GSK587323, FDC of candesartan cilexetil 16 mg and HCTZ 12.5mg | GlaxoSmithKline | Hypertension | 05/14 | 05/14 | | |
NCT00574834: Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes |
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| Terminated | 1 | 17 | US | Ramipril, Altace, HCTZ-hydrochlorothiazide, Brand Names: HydroDIURIL, Microzide, Ramipril+HCTZ, Altace and HydroDIURIL, Microzide | University of Maryland, Baltimore, King Pharmaceuticals is now a wholly owned subsidiary of Pfizer | Metabolic Syndrome | 08/14 | 08/14 | | |
NCT02121535: Bioequivalence Study of Telmisartan Between T80/A5/H12.5 mg FDC Tablet and T80/A5 mg Tab and H12.5 mg Tab Concomitant Use |
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| Completed | 1 | 72 | Japan | T80/A5 mg FDC tablet, H12.5 mg tablet, T80/A5/H12.5 ng FDC tablet, H12.5 mf tablet, T80/A5/H12.5 mg FDC tablet | Boehringer Ingelheim | Healthy | 08/14 | 08/14 | | |
NCT03390465: Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects |
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| Completed | 1 | 36 | RoW | Fimasartan/Amlodipine combination drug, Hydrochlorothiazide, FAH | Boryung Pharmaceutical Co., Ltd | Drug-Drug Interaction | 01/18 | 01/18 | | |
NCT03387657: A Drug to Drug Interaction Study of Sotagliflozin With Hydrochlorothiazide |
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| Completed | 1 | 16 | US | Sotagliflozin (SAR439954), Hydrochlorothiazide | Sanofi | Type 2 Diabetes Mellitus | 03/18 | 03/18 | | |
NCT03629067: Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects |
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| Completed | 1 | 60 | RoW | Treatment T, FAH, Treatment R, FA/H | Boryung Pharmaceutical Co., Ltd | Pharmacokinetics | 11/18 | 12/18 | | |
NCT06083116: Drug-Drug Interaction Study Between Henagliflozin Proline and Hydrochlorothiazide |
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| Completed | 1 | 12 | RoW | Hydrochlorothiazide、Henagliflozin Proline | Jiangsu HengRui Medicine Co., Ltd. | Diabetes in Adults | 10/19 | 10/19 | | |
NCT03971929: Safety and Effect Study of SHR0532 (Drug Code) Tablets in Patients With Mild Hypertension |
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| Completed | 1 | 36 | RoW | SHR0532, SHR placebo, Hydrochlorothiazide 25 mg | Jiangsu HengRui Medicine Co., Ltd. | Hypertension | 09/20 | 09/20 | | |
NCT04964050: A Bioequivalence Study Between Capozide Versus ACE-Hemmer-ratiopharm in Healthy Adult Participants Under Fasting Conditions |
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| Withdrawn | 1 | 0 | NA | Capozide, ACE-Hemmer-Ratiopharm | GlaxoSmithKline | Healthy Volunteers | 05/22 | 05/22 | | |
