| carbamazepine / Generic mfg. |
ACTRN12615000643572: EpiNet-First Trial 1: Comparison of efficacy of levetiracetam, lamotrigine and carbamazepine in people with previously untreated epilepsy who have focal seizures. |
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| Recruiting | 4 | 1467 | | | EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust | Epilepsy | | | | |
ChiCTR-OCH-09000813: Studies on the correlation associated with the mutation of genes and epilepsies |
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| Recruiting | 4 | 1500 | | carbamazepine, valproate ;none ;carbamazepine, valproate | Central South University; Hunan Provincial Science and Technology Department, Science and Technology Building, Yuelu Ave. Changsha, Natural Science Foundation of Hunan Province | epilepsy | | | | |
2008-000370-20: Evaluation of pharmacokinetic and pharmacodynamic interactions between escitalopram and drugs used for the treatment of bipolar disorders. |
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| Ongoing | 4 | 24 | Europe | Lamotrigine, Gabapentin, Carbamazepine, Oxcarbazepine, Levetiracetam, Valproic acid, CIPRALEX, LITIO CARBONATO, CIPRALEX, LITIO CARBONATO | AZIENDA OSPEDALIERA PISANA | bipolar disorders | | | | |
| Ongoing | 4 | 40 | Europe | carbamazepine, Levetiracetam, Lamotrigine, RVG 11401 (tabletten 100 mg), RVG 03899 (tabletten, RVG 29546, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine | University Medical Center Utrecht, Dutch national epilepsy fund | We will investigate possible cognitive benifits of early antiepileptic drug withdrawal after pediatric epilepsy surgery. The concerning medical condition is refractory epilepsy | | | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
STANDLOW, NCT03689114: Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy |
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| Active, not recruiting | 4 | 374 | Europe | Low dose carbamazepine, low carbamazepine, Standard dose carbamazepine, Standard carbamazepine, Low dose levetiracetam, Low levetiracetam, Standard dose levetiracetam, Standard levetiracetam, Low dose valproate, Low valproate, Standard dose valproate, Standard valproate, Low dose zonisamide, Low zonisamide, Standard dose zonisamide, Standard zonisamide, Low dose oxcarbazepine, Low oxcarbazepine, Standard dose oxcarbazepine, Standard oxcarbazepine, Low dose topiramate, Low topiramate, Standard dose topiramate, Standard topiramate, Low dose lamotrigine, Low lamotrigine, Standard dose lamotrigine, Standard lamotrigine, Low dose gabapentin, Low gabapentin, Standard dose gabapentin, Standard gabapentin | Mario Negri Institute for Pharmacological Research, Azienda Ospedaliera San Gerardo di Monza, Ministry of Health, Italy | Epilepsies, Partial | 06/24 | 08/24 | | |
NCT04996199: Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial |
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| Recruiting | 4 | 132 | RoW | Oxcarbazepine, LOVAX, Carbamazepine, zileuton | Postgraduate Institute of Dental Sciences Rohtak | Trigeminal Neuralgia | 12/21 | 01/22 | | |
ChiCTR2100053149: Clinical observation and research on traditional Chinese medicine prevention and treatment of epilepsy complicated with cognitive impairment based on the theory of removing stasis and eliminating phlegm |
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| Recruiting | 4 | 120 | | Remove blood stasis and settle lampsia mixture + carbamazepine ;Placebo + carbamazepine | Longhua Hospital, Shanghai University of Traditional Chinese Medicine; Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine Aijian Endowment Fund Supports Projects | Epilepsy with cognitive impairment | | | | |
NCT05419180: Study of Interest of Stiripentol and Carbamazepine in the Treatment of Patients With Pharmacoresistant Focal Epilepsies |
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| Recruiting | 4 | 100 | Europe | Stiripentol | Biocodex | Pharmacoresistant Focal Epilepsies | 09/23 | 01/24 | | |
NCT05748236: The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy |
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| Enrolling by invitation | 4 | 70 | RoW | Lamotrigine tablet, Lamitrin, Lamogin, Carbamazepine-Containing Product in Oral Dose Form, Tegretol | Dhaka Medical College | Focal Epilepsy | 10/23 | 10/23 | | |
ChiCTR2100048530: A randomized, double-blind, controlled, multicenter clinical trial to observe the efficacy and safety of combination therapy versus monotherapy in newly diagnosed adult focal epilepsy |
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| Not yet recruiting | 4 | 260 | | Combination of valproate and carbamazepine ;Combination of valproate-placebo and carbamazepine | The Seventh Affiliated Hospital, Sun Yat-sen University; The Seventh Affiliated Hospital, Sun Yat-sen University, The Seventh Affiliated Hospital, Sun Yat-sen University Clinical Research 735 Program | epilepsy | | | | |
| Not yet recruiting | 3 | 582 | | | Eisai Ltd, Pharmaceutical Research Associate Ltd. | Newly diagnosed partial epilepsy | | | | |
2015-000388-15: Treatment of vestibular paroxysmia with carbamazepine Carbamazepin zur Therapie der Vestibularisparoxysmie |
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| Ongoing | 3 | 153 | Europe | Capsule, hard, Timonil retard | University of the University of Munich, Bundesministerium für Bildung und Forschung | The main symptoms of vestibular paroxysmia are brief attacks of rotatory or postural vertigo lasting seconds to a few minutes with or without ear symptoms (tinnitus and hypoacusis). As in trigeminal neuralgia or hemifacial spasm, it is assumed that a neurovascular cross-compression of the eighth cranial nerve is the cause of the attacks. Patienten mit Vestibularisparoxysmei leiden unter Sekunden bis wenige Minuten andauernden Schwindelattacken, welche von Ohrsymptomen begleitet werden können. Es wird angenommen, dass die Erkrankung ähnlich wie die Trigeminusneuralgie durch einen Gefäß-Nerven-Kontakt (des achten Hirnnervens) hervorgerufen wird., The main symptoms of vestibular paroxysmia are brief attacks of vertigo lasting seconds to a few minutes, sometimes with ear symptoms. Patienten mit Vestibularisparoxysmie leiden unter sich wiederholenden Schwindelattacken, welche Sekunden bis wenige Minuten andauern und manchmal von Ohrsymptomen begleitet werden., Diseases [C] - Nervous System Diseases [C10] | | | | |
ACTRN12624000420549: CARGo: Investigating the Efficacy of Carbamazepine for the treatment of gonorrhoea in women |
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| Not yet recruiting | 2/3 | 75 | | | Gold Coast University Hospital, Gold Coast Hospital and Health Service | gonorrhoea | | | | |
NCT06316362: Efficacy of SMOF Lipid in the Management of Acute Poisoning With Carbamazepine |
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| Completed | 2 | 40 | RoW | SMOF lipid 20% | Alexandria University | Acute Poisoning | 02/23 | 02/23 | | |
ChiCTR2300070038: Efficacy of alectinib combined with carbamazepine in the treatment of symptomatic epilepsy in patients with EGFR mutant lung cancer with meningeal metastases by intrathecal injection of pemetrexed |
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| Not yet recruiting | 2 | 15 | | ntrathecal carbamazepine, ametinib, and pemetrexed | The Second Affiliated Hospital of Harbin Medical University; The Second Affiliated Hospital of Harbin Medical University, Beijing Xisike Clinical Oncology Research Foundation | Symptomatic epilepsy in meningeal metastases from lung cancer | | | | |
2018-002633-38: MCDS-Therapy - Repurposing of carbamazepine (CBZ) for the treatment of skeletal dysplasia in children |
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| Not yet recruiting | 1/2 | 40 | Europe | Tegretol 100mg Tablets, Tegretol 200mg Tablets, Tegretol Liquid 100mg/5ml, Tegretol 400mg tablets, [Tegretol 200 mg], [Tegretol 400 mg], [Tegretol 20 mg/mL Sciroppo], [DIBASE 10.000 U.I./ml], Tablet, Oral liquid, Tegretol 100mg Tablets, Tegretol 200mg Tablets, Tegretol Liquid 100mg/5ml, Tegretol 400mg tablets | The Newcastle upon Tyne Hospitals NHS Foundation Trust, ISTITUTO ORTOPEDICO RIZZOLI, European Commission Horizon 2020, Comunità Europea | Metaphyseal chondrodysplasia type Schmid (MCDS), Metaphyseal chondrodysplasia, Schmid type (MCDS), is a very rare inherited disorder characterized by short stature with abnormally short arms and legs (short-limbed dwarfism) and bowed legs (genu varu, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
ACTRN12623001038684: A drug-drug interaction trial between AR882, fluconazole, carbamazepine, celecoxib, and sulfasalazine in healthy particpants |
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| Recruiting | 1 | 54 | | | Arthrosi Therapeutics Australia Pty, Ltd a subsidiary of Arthrosi Therapeutics, Inc, Arthrosi Therapeutics Australia Pty, Ltd a subsidiary of Arthrosi Therapeutics, Inc. | Gout | | | | |
NCT05418582: Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine |
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| Completed | 1 | 40 | US | DZD9008 and intraconazole, DZD9008 and carbamazepine | Dizal Pharmaceuticals | Healthy Subjects | 06/22 | 12/22 | | |
NCT05594602: Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects. |
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| Completed | 1 | 36 | US | EDP-235, Itraconazole, Carbamazepine, Quinidine | Enanta Pharmaceuticals, Inc | COVID-19 | 12/22 | 12/22 | | |
NCT05581823: Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants |
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| Completed | 1 | 16 | US | Tavapadon, CVL-751, PF-06649751, Carbamazepine | Cerevel Therapeutics, LLC | Parkinson Disease | 01/23 | 02/23 | | |
NCT05552196: A Study of Ponesimod in Healthy Adult Participants |
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| Completed | 1 | 28 | Europe | Ponesimod, JNJ-67896153, ACT-128800, Ponvory, Carbamazepine, Tegretol | Janssen Pharmaceutica N.V., Belgium | Healthy | 03/23 | 03/23 | | |
NCT05824143: Open-label Trial to Evaluate the Effect Carbamazepine on Darigabat Pharmacokinetics in Healthy Adult Participants |
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| Completed | 1 | 13 | US | Darigabat, CVL-865, Carbamazepine | Cerevel Therapeutics, LLC | Healthy Participants | 07/23 | 07/23 | | |
NCT05860933: A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants |
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| Completed | 1 | 30 | US | LY3537982, Itraconazole, Carbamazepine | Eli Lilly and Company, Loxo Oncology, Inc. | Healthy | 08/23 | 08/23 | | |
NCT05994807: A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants |
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| Completed | 1 | 33 | US | DC-806, Itraconazole, Carbamazepine | DICE Therapeutics, Inc. | Healthy Volunteers | 09/23 | 09/23 | | |
PK, NCT06005688: A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants |
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| Completed | 1 | 12 | Europe | Vepdegestrant, ARV-471, PF-07850327, Carbamazepine, Tegretol | Pfizer, Arvinas Estrogen Receptor, Inc. | Healthy Participants | 10/23 | 11/23 | | |
NCT05932303: A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy Participants |
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| Completed | 1 | 47 | Canada | BMS-986278, Itraconazole, Gemfibrozil, Carbamazepine | Bristol-Myers Squibb | Healthy Participants | 10/23 | 10/23 | | |
NCT06028464: A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of BI 1810631 in the Blood |
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| Completed | 1 | 16 | Europe | BI 1810631, Carbamazepine | Boehringer Ingelheim | Healthy | 12/23 | 12/23 | | |
NCT05840952: A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558 |
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| Recruiting | 1 | 144 | Europe | ALG-097558, Placebo, Midazolam, Itraconazole, Carbamazepine, ALG-097558 in solution formulation, ALG-097558 in tablet formulation | Aligos Therapeutics | COVID-19 | 04/24 | 07/24 | | |
NCT05965219: A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants |
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| Completed | 1 | 60 | US | Emraclidine, Itraconazole, Sporanox, Carbamazepine, Tegretol-XR, Metformin, Glucophage | Cerevel Therapeutics, LLC | Healthy Volunteers | 11/23 | 11/23 | | |
NCT06173596: A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults |
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| Completed | 1 | 60 | Europe | ALXN2080, Itraconazole, Fluconazole (AxMP), Carbamazepine (AxMP) | Alexion Pharmaceuticals, Inc. | Healthy | 04/24 | 05/24 | | |
NCT06071442: Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine |
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| Completed | 1 | 60 | US | Vemircopan, ALXN2050, Rosuvastatin, Metformin, Levonorgestrel / Ethinyl Estradiol, SIMPESSE, Carbamazepine | Alexion Pharmaceuticals, Inc. | Healthy Participants | 04/24 | 04/24 | | |
NCT06345794: A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants |
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| Recruiting | 1 | 50 | US | LY4100511 (DC-853), DC-853, Itraconazole, Fluconazole, Carbamazepine | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, Eli Lilly and Company | Healthy | 06/24 | 06/24 | | |
NCT06348888: A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants |
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| Completed | 1 | 30 | US | BAY2927088, Itraconazole, Carbamazepine | Bayer | Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers | 06/24 | 06/24 | | |
NCT06370728: A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants |
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| Recruiting | 1 | 30 | US | Orforglipron, LY3502970, Carbamazepine | Eli Lilly and Company | Healthy | 07/24 | 07/24 | | |
| Recruiting | 1 | 20 | Canada | Carbamazepine, Tegretol, Lorazepam, Ativan, Dextromethorphan, Robitussin, Nimodipine, Nimotop, Placebo, Sugar | University Health Network, Toronto | Low Intensity Focussed Ultrasound | 05/25 | 05/26 | | |
ChiCTR-IOR-17010341: Clinical Research of Nerve Patch applying to Microvascular Decompression Surgery |
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| Recruiting | N/A | 72 | | carbamazepines ;use nerve patch to have microvascular decompression surgery | SHANGHAI CHEST HOSPITAL SHANGHAI JIAOTONG UNIVERSITY; SHANGHAI CHEST HOSPITAL SHANGHAI JIAOTONG UNIVERSITY, Shanghai Hospital Development Center | Primary Trigeminal Neuralgia | | | | |
ChiCTR1800019233: Therapeutic effect of acupuncture myofascial trigger points on primary trigeminal neuralgia |
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| Recruiting | N/A | 40 | | Acupuncture myofascial trigger point ;Oral carbamazepine | Shanghai University of Sport; East China Hospital, National Natural Science Foundation of China (B5-8000-14-0008) | Trigeminal neuralgia | | | | |
ChiCTR1900027873: Pre-experimental study of the central response of electroacupuncture on trigeminal neuralgia based on resting state functional magnetic resonance imaging |
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| Not yet recruiting | N/A | 16 | | Electroacupuncture and carbamazepine ;carbamazepine ;none | The Third Affiliated Hospital of Zhejiang Chinese Medical University; The Third Affiliated Hospital of Zhejiang Chinese Medical University, Project funds of the third affiliated hospital of zhejiang province | trigeminal neuralgia | | | | |
| Recruiting | N/A | 92 | | bloodletting ;carbamazepine | Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University; Beijing Hospital of TCM, Beijing municipal health and family planning commission | primary trigeminal neuralgia | | | | |
levcbz, NCT06138847: Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy? |
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| Active, not recruiting | N/A | 119 | RoW | electroencephalogram | İpek Dokurel | Epilepsy; Syndrome, Seizures of Localized Onset | 08/23 | 12/23 | | |
NCT05833399: Correlation of Genetic Variations With Clinical Response in Substance Use Disorder |
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| Recruiting | N/A | 200 | RoW | Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone, Seroquel, Olapex, Remeron, Tegretol, Moodapex, Tryptizol, Neurazine and Apexidone. | Alexandria University | Substance Use Disorders, Substance Dependence | 03/24 | 12/24 | | |
NCT06357260: Pregabalin as an add-on Therapy to Carbamazepine in Trigeminal Neuralgia Patients |
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| Recruiting | N/A | 50 | RoW | Pregabalin and Carbamazepine, Test group, Carbamazepine, Control group | Postgraduate Institute of Dental Sciences Rohtak | Trigeminal Neuralgia | 02/25 | 03/25 | | |
| Recruiting | N/A | 1000 | Europe | Valproic acid, carbamazepine, phenobarbital, phenytoin, levetiracetam, lamotrigine, topiramate, oxcarbazepine, stiripentol, clobazam, brivaracétam, felbamate, lacosamide, rufinamide, gabapentine, pregabaline, sultiame, tiagabine, vigabatrine, mesuximide, primidone, perampanel, ethosuximide, zonisamide, cannabidiol, genetic polymorphisms | Assistance Publique - Hôpitaux de Paris | Epilepsy | 06/26 | 06/26 | | |
| Recruiting | N/A | 10400 | | carbamazepine ;sodium valproate ;lamotrigine ;topiramate ;oxcarbazepine ;levetiracetam ;gabapentin ;phenytoin ;phenobarbital ;clonazepam ;The antiepileptic drug 1 which will obtain marketing authorization in China in the future ;The antiepileptic drug 2 which will obtain marketing authorization in China in the future ;The antiepileptic drug 3 which will obtain marketing authorization in China in the future | The Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Medical Association | epilepsy | | | | |
ACTRN12618001052224: Comparison in efficacy of carbamazepine, oxcarbazepine and baclofen in the management of trigeminal neuralgia: a double blinded randomised clinical trial |
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| Not yet recruiting | N/A | 36 | | | Mohsin Fazal , Mohsin Fazal | Trigeminal neuralgia , Psychogenic pain | | | | |