| carbamazepine / Generic mfg. |
2022-001005-43: Etude de l’intérêt de l’association du stiripentol (Diacomit®) et de la carbamazépine dans le traitement des patients atteints d’épilepsies focales pharmacorésistantes. |
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| | 4 | 30 | Europe | DIACOMIT, carbamazepine, Powder for oral suspension in sachet, , Capsule, hard, DIACOMIT 250 mg, carbamazepine, DIACOMIT 500 mg | Biocodex, BIOCODEX | L’association carbamazépine/stiripentol est utilisée dans la pratique quotidienne à l’hôpital Necker chez les enfants atteints d’épilepsies focales. Il est donc pertinent d’étudier l’impact de cette association., L’association carbamazépine/stiripentol est utilisée dans la pratique quotidienne à l’hôpital Necker chez les enfants atteints d’épilepsies focales., Diseases [C] - Nervous System Diseases [C10] | | | | |
ACTRN12615000643572: EpiNet-First Trial 1: Comparison of efficacy of levetiracetam, lamotrigine and carbamazepine in people with previously untreated epilepsy who have focal seizures. |
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| Recruiting | 4 | 1467 | | | EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust | Epilepsy | | | | |
NCT00207428: Antiepileptic Drug Carbamazepine in Treatment of Bronchial Asthma |
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| Completed | 4 | 65 | RoW | Carbamazepine | Centre of Chinese Medicine, Georgia, Rea Rehabilitation Centre, Georgia | Bronchial Asthma | | 04/00 | | |
| Completed | 4 | | US | lorazepam (Ativan), carbamazepine (Tegretol) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcoholism | | 12/00 | | |
NCT00006395: Drug Interaction Study of Tegretol (Carbamazepine) and St. John's Wort in Normal Volunteers |
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| Completed | 4 | 12 | US | St. John's Wort | National Institutes of Health Clinical Center (CC) | Healthy | | 04/01 | | |
NCT00153296: Study of Efficacy of Carbamazepine in Therapy of Patients With Moderate Persistent and Severe Bronchial Asthma |
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| Completed | 4 | 68 | RoW | Carbamazepine | Centre of Chinese Medicine, Georgia, Rea Rehabilitation Centre, Georgia | Bronchial Asthma | | 04/05 | | |
| Completed | 4 | 353 | US | Carbamazepine | National Institute on Drug Abuse (NIDA), VA Office of Research and Development | Cocaine-Related Disorders, Substance-Related Disorders | | 06/05 | | |
NCT00216567: Safety and Efficacy of Topamax Versus Carbamazepine in Benign Rolandic Epilepsy |
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| Completed | 4 | 114 | RoW | topamax | Janssen Korea, Ltd., Korea | Epilepsy, Rolandic | | 02/06 | | |
| Completed | 4 | 120 | Europe, RoW | olanzapine, carbamazepine | Eli Lilly and Company | Bipolar Disorder | | 06/06 | | |
NCT00260247: Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine. |
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| Completed | 4 | 10 | Europe | carbamazepine oxcarbazepine | Odense University Hospital, Danish Research Agency, Novartis | Metabolic Clearance Rate | 10/06 | 10/06 | | |
NCT00203567: Carbamazepine Extended-Release for the Treatment of Bipolar Depression |
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| Completed | 4 | 25 | US | carbamazepine ER | Tuscaloosa Research & Education Advancement Corporation, Shire | Bipolar Depression | 02/07 | 05/08 | | |
NCT00181870: Equetro for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder |
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| Completed | 4 | 33 | US | carbamazepine ER (Equetro) | Massachusetts General Hospital, Shire | Bipolar Disorder, Mania | 08/07 | | | |
| Completed | 4 | 161 | US | Extended-Release Carbamazepine | Validus Pharmaceuticals | Bipolar I Disorder | 10/07 | 10/07 | | |
NCT00325286: Open Label Study of Lithium Plus Extended-Release Carbamazepine (ERC-CBZ) for Rapid Cycling Bipolar Disorder |
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| Unknown status | 4 | 20 | US | Lithium Plus Extended- Release Carbamazepine, Epitol, Tegretol | Creighton University, Shire | Bipolar Disorder | | 03/08 | | |
NCT00896987: Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies |
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| Completed | 4 | 121 | RoW | lamotrigine (Lamictal), lamictal, Carbamazepine (Tegretol), Tegretol | Korean Epilepsy Society, GlaxoSmithKline | Epilepsy | 12/08 | 12/08 | | |
| Completed | 4 | 200 | RoW | zonisamide, carbamazepine | Eisai Korea Inc. | Epilepsy | 05/09 | 07/09 | | |
2007-004226-25: Low-dose intravenous immunoglobulin or 0.9% saline in the treatment of trigeminal neuralgia refractory to carbamazepine – a randomized double blind parallel placebo-controlled multicentre trial in an outpatient setting. |
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| Terminated | 4 | 32 | Europe | Gamunex, Intravenous infusion | UCL, | Trigeminal neuralgia is a severe neuropathic facial pain that currently can often not be well controlled pharmacologically. The gold standard for medical treatment remains carbamazepine, which may produce severe side effects and numerous drug interactions, or may not be effective. There is a recognized need to find other drugs that will provide pain relief with fewer side effects than carbamazepine, or in such cases where carbamazepine is without effect. | | | | |
| Completed | 4 | 361 | Europe | Levetiracetam, Carbamazepine, Lamotrigine | Johannes Gutenberg University Mainz, UCB Pharma GmbH | Focal Epilepsy | 07/10 | 08/11 | | |
NCT01089855: Efficacy and Tolerability of Carbamazepine CR in Diabetic Neuropathy Pain |
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| Completed | 4 | 123 | RoW | Carbamazepine | Novartis | Neuropathic Pain | 07/10 | | | |
NCT00807989: The Efficacy and Safety of Low Dose Combination of LTG and VPA Compared to CBZ Monotherapy |
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| Completed | 4 | 207 | RoW | Carbamazepine, Lamotrigine/Valproate | Yonsei University | Epilepsy | 05/12 | 05/12 | | |
| Completed | 4 | 40 | RoW | lithium plus carbamazepine, lithium plus valproate | University of Sao Paulo | Bipolar I Disorder | 06/12 | 06/12 | | |
NCT02208492: The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study |
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| Completed | 4 | 75 | RoW | Levetiracetam, Carabamazepine | Yonsei University | Focal Epilepsy | 12/13 | 02/14 | | |
NCT02870283: Cost- Effectiveness and Quality of Life Assessment in Mood Disorder |
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| Completed | 4 | 107 | NA | Lithium, carbolitium, Valproic Acid, depakene, Carbamazepine, tegretol | Federal University of Rio Grande do Sul | Bipolar Disorder | 11/14 | 09/15 | | |
ChiCTR-OCH-09000813: Studies on the correlation associated with the mutation of genes and epilepsies |
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| Recruiting | 4 | 1500 | | carbamazepine, valproate ;none ;carbamazepine, valproate | Central South University; Hunan Provincial Science and Technology Department, Science and Technology Building, Yuelu Ave. Changsha, Natural Science Foundation of Hunan Province | epilepsy | | | | |
2008-000370-20: Evaluation of pharmacokinetic and pharmacodynamic interactions between escitalopram and drugs used for the treatment of bipolar disorders. |
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| Ongoing | 4 | 24 | Europe | Lamotrigine, Gabapentin, Carbamazepine, Oxcarbazepine, Levetiracetam, Valproic acid, CIPRALEX, LITIO CARBONATO, CIPRALEX, LITIO CARBONATO | AZIENDA OSPEDALIERA PISANA | bipolar disorders | | | | |
| Ongoing | 4 | 40 | Europe | carbamazepine, Levetiracetam, Lamotrigine, RVG 11401 (tabletten 100 mg), RVG 03899 (tabletten, RVG 29546, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine | University Medical Center Utrecht, Dutch national epilepsy fund | We will investigate possible cognitive benifits of early antiepileptic drug withdrawal after pediatric epilepsy surgery. The concerning medical condition is refractory epilepsy | | | | |
NCT02214615: Carbamazapine for Inherited Erythromelalgia Patients With NaV1.7 Mutations |
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| Completed | 4 | 2 | US | Carbamazepine, Tegretol, Placebo | VA Connecticut Healthcare System | Erythromelalgia | 07/16 | 07/16 | | |
NCT02705768: Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures |
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| Completed | 4 | 90 | RoW | Carbamazepine, Tegretol, Oxcarbazepine, Oxetol | All India Institute of Medical Sciences, Bhubaneswar | Seizures, Focal | 02/17 | 03/17 | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
NCT02912364: Comparison of the Cognitive and Behavioral Effects of Eslicarbazepine Acetate and Carbamazepine in Healthy Adults |
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| Completed | 4 | 46 | US | Eslicarbazepine, Aptiom, Carbamazepine, Tegretol | Stanford University, Sunovion | Epilepsy | 04/18 | 04/18 | | |
| Unknown status | 4 | 160 | Europe | Ketogenic diet, Antiepileptic drug therapy, Carbamazepine, Clobazam, Clonazepam, Ethosuximide, Lacosmide, Lamotrigine, Levetiracetam, Nitrazepam, Phenytoin, Rufinamide, Sodium Valproate, Stiripentol, Topiramate, Vigabatrin, Zonisamide | University College, London, Great Ormond Street Hospital for Children NHS Foundation Trust, Cambridge University Hospitals NHS Foundation Trust, Alder Hey Children's NHS Foundation Trust, Bristol Royal Hospital for Children, Birmingham Women's and Children's NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, Manchester University NHS Foundation Trust, Sheffield Children's NHS Foundation Trust, National Institute for Health Research, United Kingdom, Lancashire Care NHS Foundation Trust, Newcastle-upon-Tyne Hospitals NHS Trust, St George's University Hospitals NHS Foundation Trust | Epilepsy | 06/18 | 06/19 | | |
NCT02623504: DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder |
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| Terminated | 4 | 17 | US | Carbamazepine, Equetro, Placebo | Validus Pharmaceuticals | Bipolar Disorder | 11/18 | 11/18 | | |
NCT03161509: Pharmacokinetics of Paracetamol and Antiepileptic Drugs After Sleeve Gastrectomy |
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| Terminated | 4 | 2 | RoW | Paracetamol, Antiepileptic (either carbamazepine, lamotrigine, phenytoin or valproic acid), Antiepileptic | Rambam Health Care Campus | Bariatric Surgery Candidate | 12/18 | 01/19 | | |
NCT04967326: Role of Clinical Pharmacists in Epilepsy Management |
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| Completed | 4 | 141 | NA | Optimizing therapy with antiepileptic drugs (carbamazepine, phenytoin, valproic acid) | Gia Dinh People Hospital | Epilepsy | 12/18 | 12/18 | | |
| Terminated | 4 | 5 | Europe | Carbamazepine, Levetiracetam, Parent based sleep (PBS) intervention, CASTLE Online Sleep Intervention (COSI) | King's College London, King's College Hospital NHS Trust, University of Liverpool, Bangor University, Edge Hill University, Oxford Brookes University | Rolandic Epilepsy | 09/20 | 09/20 | | |
NCT03307863: Effect of Anti-epileptic Drugs on Etonogestrel-releasing Implant Pharmacokinetics in Women With Epilepsy |
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| Unknown status | 4 | 69 | RoW | Carbamazepine-Implant, Topiramate-Implant, Implant | University of Sao Paulo | Contraception, Drug Interactions | 11/20 | 11/20 | | |
NCT03490487: Electroclinical Effect of Steroid in Patients With Benign Childhood Epilepsy With Centrotemporal Spikes |
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| Unknown status | 4 | 100 | RoW | conventional antiepileptic drugs, carbamazepine, valproate, oxcarbazepine or levetiracetam, oral steroid, Prednisolone | Assiut University | Benign Childhood Epilepsy With Centrotemporal Spikes | 12/20 | 12/20 | | |
STANDLOW, NCT03689114: Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy |
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| Active, not recruiting | 4 | 374 | Europe | Low dose carbamazepine, low carbamazepine, Standard dose carbamazepine, Standard carbamazepine, Low dose levetiracetam, Low levetiracetam, Standard dose levetiracetam, Standard levetiracetam, Low dose valproate, Low valproate, Standard dose valproate, Standard valproate, Low dose zonisamide, Low zonisamide, Standard dose zonisamide, Standard zonisamide, Low dose oxcarbazepine, Low oxcarbazepine, Standard dose oxcarbazepine, Standard oxcarbazepine, Low dose topiramate, Low topiramate, Standard dose topiramate, Standard topiramate, Low dose lamotrigine, Low lamotrigine, Standard dose lamotrigine, Standard lamotrigine, Low dose gabapentin, Low gabapentin, Standard dose gabapentin, Standard gabapentin | Mario Negri Institute for Pharmacological Research, Azienda Ospedaliera San Gerardo di Monza, Ministry of Health, Italy | Epilepsies, Partial | 06/24 | 08/24 | | |
NCT04996199: Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial |
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| Recruiting | 4 | 132 | RoW | Oxcarbazepine, LOVAX, Carbamazepine, zileuton | Postgraduate Institute of Dental Sciences Rohtak | Trigeminal Neuralgia | 12/21 | 01/22 | | |
ChiCTR2100053149: Clinical observation and research on traditional Chinese medicine prevention and treatment of epilepsy complicated with cognitive impairment based on the theory of removing stasis and eliminating phlegm |
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| Recruiting | 4 | 120 | | Remove blood stasis and settle lampsia mixture + carbamazepine ;Placebo + carbamazepine | Longhua Hospital, Shanghai University of Traditional Chinese Medicine; Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine Aijian Endowment Fund Supports Projects | Epilepsy with cognitive impairment | | | | |
NCT05419180: Study of Interest of Stiripentol and Carbamazepine in the Treatment of Patients With Pharmacoresistant Focal Epilepsies |
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| Recruiting | 4 | 100 | Europe | Stiripentol | Biocodex | Pharmacoresistant Focal Epilepsies | 09/23 | 01/24 | | |
NCT05748236: The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy |
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| Enrolling by invitation | 4 | 70 | RoW | Lamotrigine tablet, Lamitrin, Lamogin, Carbamazepine-Containing Product in Oral Dose Form, Tegretol | Dhaka Medical College | Focal Epilepsy | 10/23 | 10/23 | | |
ChiCTR2100048530: A randomized, double-blind, controlled, multicenter clinical trial to observe the efficacy and safety of combination therapy versus monotherapy in newly diagnosed adult focal epilepsy |
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| Not yet recruiting | 4 | 260 | | Combination of valproate and carbamazepine ;Combination of valproate-placebo and carbamazepine | The Seventh Affiliated Hospital, Sun Yat-sen University; The Seventh Affiliated Hospital, Sun Yat-sen University, The Seventh Affiliated Hospital, Sun Yat-sen University Clinical Research 735 Program | epilepsy | | | | |
