| carbamazepine / Generic mfg. |
ACTRN12623001038684: A drug-drug interaction trial between AR882, fluconazole, carbamazepine, celecoxib, and sulfasalazine in healthy particpants |
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| Recruiting | 1 | 54 | | | Arthrosi Therapeutics Australia Pty, Ltd a subsidiary of Arthrosi Therapeutics, Inc, Arthrosi Therapeutics Australia Pty, Ltd a subsidiary of Arthrosi Therapeutics, Inc. | Gout | | | | |
NCT02253849: Effects of TPV/r on the Pharmacokinetics of Carbamazepine in Healthy Adult Volunteers |
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| Completed | 1 | 28 | Europe | Carbamazepine, Tipranavir, Ritonavir | Boehringer Ingelheim | Healthy | 06/06 | | | |
NCT00892125: A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder |
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| Completed | 1 | 64 | US | paliperidone ER; Carbamazepine | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Schizophrenia, Bipolar Disorder | | 03/07 | | |
NCT02284854: Pharmacokinetic Interaction Study Between Eslicarbazepine Acetate and Carbamazepine |
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| Completed | 1 | 43 | Europe | BIA 2-093, Eslicarbazepine acetate, ESL, Carbamazepine, CBZ | Bial - Portela C S.A. | Epilepsy | 11/09 | 11/09 | | |
NCT01365403: A Study on The Effect of Multiple Dose Carbamazepine on Single Dose Pharmacokinetics of RO4917838 in Healthy Volunteers |
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| Completed | 1 | 16 | Europe | RO4917838, carbamazepine | Hoffmann-La Roche | Healthy Volunteer | 07/11 | 07/11 | | |
NCT01635829: A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir |
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| Completed | 1 | 24 | Europe | Telaprevir, Phenytoin, Carbamazepine | Janssen Infectious Diseases BVBA | Healthy Participants | 08/12 | 09/12 | | |
NCT01629368: A Study of the Effect of Carbamazepine on the Pharmacokinetics of RO4917523 in Healthy Volunteers |
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| Completed | 1 | 16 | Europe | Carbamazepine, RO4917523 | Hoffmann-La Roche | Healthy Volunteer | 09/12 | 09/12 | | |
NCT01707407: A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects |
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| Completed | 1 | 32 | US | Pomalidomide, (CC-4047), Ketoconazole, Fluvoxamine, Carbamazepine | Celgene | Pharmacology, Clinical, Healthy | 11/12 | 11/12 | | |
NCT01530022: Crossover Study of Neuropsychological Effects of Lacosamide and Carbamazepine Immediate Release in Healthy Subjects |
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| Completed | 1 | 60 | US | Lacosamide (LCM), Vimpat, Carbamazepine Immediate Release (CBZ-IR), Tegretol IR | UCB Pharma | Healthy | 01/14 | 01/14 | | |
| Completed | 1 | 16 | US | DTG, CBZ | ViiV Healthcare, GlaxoSmithKline | Infection, Human Immunodeficiency Virus | 01/14 | 01/14 | | |
| Completed | 1 | 20 | RoW | Auration CR Tablets 400 Single Dose-Tegretol CR 400 Single Dose, Carbamazepine, Carbamazepine CR, Carbamazepine CR 400 millligrams, Tegretol CR 400 Single Dose-Auration CR 400 Single Dose, Carbamazepine CR 400 | Center for Clinical Pharmacology Research Bdbeq S.A. | Bio-equivalence Study, Fed Conditions | 06/14 | 06/14 | | |
| Completed | 1 | 21 | US | Oxcarbazepine (brand name vs generic drugs), Divalproex Sodium (brand name vs generic drugs), Carbamazepine (brand name vs generic drugs), Lamotrigine (brand name vs generic drugs), levetiracetam (brand name vs generic drugs), Topiramate (brand name vs generic drugs), Zonisamide (brand name vs generic drugs), Phenytoin sodium (brand name vs generic drugs) | Food and Drug Administration (FDA), University of Maryland, Baltimore | Epilepsy | 08/18 | 09/18 | | |
NCT04784000: Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527 |
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| Completed | 1 | 20 | Canada | Period 1: AT-527 550 mg, AT-527 is also known as RO7496998, Period 2: carbamazepine, Period 3: AT-527 550 mg + carbamazepine, Period 3: AT-527 1100 mg + carbamazepine | Atea Pharmaceuticals, Inc., Hoffmann-La Roche | Healthy Volunteer Study | 04/21 | 04/21 | | |
NCT04783753: Drug-Drug Interaction Study Between EDP-514, Itraconazole, Carbamazepine, and Quinidine in Healthy Subjects |
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| Completed | 1 | 72 | US | EDP-514, Itraconazole, Carbamazepin, Quinidine | Enanta Pharmaceuticals, PRA Health Sciences | Hepatitis B | 06/21 | 07/21 | | |
NCT04962230: Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir |
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| Completed | 1 | 12 | US | PF-07321332/ritonavir, Carbamazepine, PF 07321332/ritonavir | Pfizer | Healthy Participant | 10/21 | 10/21 | | |
NCT05028608: A Study to Learn What Happens to Elinzanetant in the Body When Taken With or Without Carbamazepine, and How Safe it is in Healthy Men and Women Aged 18 to 60 Years. |
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| Completed | 1 | 16 | Europe | Elinzanetant (BAY3427080), NT-814, Midazolam, Carbamazepine | Bayer | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men | 10/21 | 01/22 | | |
NCT04840888: A Study of LY3484356 in Healthy Female Participants |
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| Completed | 1 | 82 | US | LY3484356, Omeprazole, Itraconazole, Carbamazepine | Eli Lilly and Company | Healthy | 04/22 | 04/22 | | |
NCT05205447: Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants |
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| Terminated | 1 | 27 | US | LY3410738, Itraconazole, Carbamazepine | Eli Lilly and Company, Loxo Oncology, Inc. | Healthy | 04/22 | 04/22 | | |
| Completed | 1 | 18 | Europe | Tepotinib, Carbamazepine | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Healthy | 05/22 | 05/22 | | |
NCT05418582: Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine |
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| Completed | 1 | 40 | US | DZD9008 and intraconazole, DZD9008 and carbamazepine | Dizal Pharmaceuticals | Healthy Subjects | 06/22 | 12/22 | | |
NCT04330248: A Study of Steady-state Carbamazepine on the Single-dose of Erdafitinib Tablets in Healthy Adult Participants |
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| Completed | 1 | 15 | Europe | Erdafitinib, JNJ-42756493, Carbamazepine | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Healthy | 06/22 | 06/22 | | |
| Completed | 1 | 14 | Europe | Evobrutinib, M2951, Carbamazepine | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Healthy | 07/22 | 07/22 | | |
NCT05486949: Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine |
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| Completed | 1 | 32 | US | AZD4205 and carbamazepine, AZD4205 and itraconazole | Dizal Pharmaceuticals | Healthy Subjects | 10/22 | 10/22 | | |
NCT05594602: Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects. |
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| Completed | 1 | 36 | US | EDP-235, Itraconazole, Carbamazepine, Quinidine | Enanta Pharmaceuticals, Inc | COVID-19 | 12/22 | 12/22 | | |
NCT05581823: Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants |
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| Completed | 1 | 16 | US | Tavapadon, CVL-751, PF-06649751, Carbamazepine | Cerevel Therapeutics, LLC | Parkinson Disease | 01/23 | 02/23 | | |
NCT05552196: A Study of Ponesimod in Healthy Adult Participants |
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| Completed | 1 | 28 | Europe | Ponesimod, JNJ-67896153, ACT-128800, Ponvory, Carbamazepine, Tegretol | Janssen Pharmaceutica N.V., Belgium | Healthy | 03/23 | 03/23 | | |
NCT05824143: Open-label Trial to Evaluate the Effect Carbamazepine on Darigabat Pharmacokinetics in Healthy Adult Participants |
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| Completed | 1 | 13 | US | Darigabat, CVL-865, Carbamazepine | Cerevel Therapeutics, LLC | Healthy Participants | 07/23 | 07/23 | | |
NCT05860933: A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants |
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| Completed | 1 | 30 | US | LY3537982, Itraconazole, Carbamazepine | Eli Lilly and Company, Loxo Oncology, Inc. | Healthy | 08/23 | 08/23 | | |
NCT05994807: A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants |
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| Completed | 1 | 33 | US | DC-806, Itraconazole, Carbamazepine | DICE Therapeutics, Inc. | Healthy Volunteers | 09/23 | 09/23 | | |
PK, NCT06005688: A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants |
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| Completed | 1 | 12 | Europe | Vepdegestrant, ARV-471, PF-07850327, Carbamazepine, Tegretol | Pfizer, Arvinas Estrogen Receptor, Inc. | Healthy Participants | 10/23 | 11/23 | | |
NCT05932303: A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy Participants |
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| Completed | 1 | 47 | Canada | BMS-986278, Itraconazole, Gemfibrozil, Carbamazepine | Bristol-Myers Squibb | Healthy Participants | 10/23 | 10/23 | | |
NCT06028464: A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of BI 1810631 in the Blood |
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| Completed | 1 | 16 | Europe | BI 1810631, Carbamazepine | Boehringer Ingelheim | Healthy | 12/23 | 12/23 | | |
NCT05840952: A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558 |
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| Recruiting | 1 | 144 | Europe | ALG-097558, Placebo, Midazolam, Itraconazole, Carbamazepine, ALG-097558 in solution formulation, ALG-097558 in tablet formulation | Aligos Therapeutics | COVID-19 | 04/24 | 07/24 | | |
NCT05965219: A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants |
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| Completed | 1 | 60 | US | Emraclidine, Itraconazole, Sporanox, Carbamazepine, Tegretol-XR, Metformin, Glucophage | Cerevel Therapeutics, LLC | Healthy Volunteers | 11/23 | 11/23 | | |
NCT06173596: A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults |
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| Completed | 1 | 60 | Europe | ALXN2080, Itraconazole, Fluconazole (AxMP), Carbamazepine (AxMP) | Alexion Pharmaceuticals, Inc. | Healthy | 04/24 | 05/24 | | |
NCT06071442: Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine |
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| Completed | 1 | 60 | US | Vemircopan, ALXN2050, Rosuvastatin, Metformin, Levonorgestrel / Ethinyl Estradiol, SIMPESSE, Carbamazepine | Alexion Pharmaceuticals, Inc. | Healthy Participants | 04/24 | 04/24 | | |
NCT06345794: A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants |
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| Recruiting | 1 | 50 | US | LY4100511 (DC-853), DC-853, Itraconazole, Fluconazole, Carbamazepine | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, Eli Lilly and Company | Healthy | 06/24 | 06/24 | | |
NCT06348888: A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants |
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| Completed | 1 | 30 | US | BAY2927088, Itraconazole, Carbamazepine | Bayer | Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers | 06/24 | 06/24 | | |
NCT06370728: A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants |
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| Recruiting | 1 | 30 | US | Orforglipron, LY3502970, Carbamazepine | Eli Lilly and Company | Healthy | 07/24 | 07/24 | | |
| Recruiting | 1 | 20 | Canada | Carbamazepine, Tegretol, Lorazepam, Ativan, Dextromethorphan, Robitussin, Nimodipine, Nimotop, Placebo, Sugar | University Health Network, Toronto | Low Intensity Focussed Ultrasound | 05/25 | 05/26 | | |
