tramadol hydrochloride / Generic mfg.  >>  Phase 4
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114 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
tramadol hydrochloride / Generic mfg.
ACTRN12609000875202: The effect of tramadol analgesia on post-operative ventilation duration in post-surgical neonates

Not yet recruiting
4
100
 
The Royal Children's Hospital
Need for mechanical ventilation in post-surgical neonates
 
 
ACTRN12606000201572: The effect of rate of administration of tramadol on incidence of post operative nausea and vomiting after any surgical operation for which significant postoperative pain is expected

Not yet recruiting
4
150
 
ANZCA (australaian and New Zealand College of Anaesthetists), Australian and New Zealand College of Anaesthetists Project Grant
Post operative nausea and vomiting
 
 
ACTRN12605000246684: Safety of Tramadol in Breastfeeding

Recruiting
4
75
 
Professor Michael Paech, ANZCA Research Grant 2004
Post Caesarean Section Analgesia and Breastfeeding
 
 
ACTRN12611001018909: Tramadol administration in the critically ill

Completed
4
15
 
Guy Ludbrook, University of Adelaide
Intensive Care Unit (ICU) Step Down patients who require patient controlled analgesia (PCA) Fentanyl as part of their management after trauma or surgery.
 
 
ACTRN12619001709134: Analgesic efficacy when extracting lower third molars

Recruiting
4
68
 
María Cristina Vallecillo Rivas, Master of Oral Surgery and Implantology. Faculty of Dentistry, University of Granada
Third molar extraction
 
 
2006-002901-30: Tramadol iv. : influence of dose and dose intervals on therapeutic accuracy and side effects when used for postoperative pain relief in ambulatory surgery

Completed
4
200
Europe
Tramadol, Solution for injection
University Hospital Ghent
ASA I and II
 
 
NCT00290901: Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.

Completed
4
754
US
Tramadol Hydrochloride 50mg, Celebrex 200mg
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Back Pain
12/06
 
BATPCAH, NCT00510666: Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy

Completed
4
841
RoW
Saline, SA, Butorphanol tartrate, BT, Tramadol Hydrochloride, TH, PS
Nanjing Medical University, HRSA/Maternal and Child Health Bureau
Postoperative Pain, Hysterectomy
05/07
05/07
NCT00399178 / 2006-003233-32: A Randomised Open Controlled Parallel Group Study Comparing Norspan and Tramadol

Completed
4
160
Europe
Transdermal delivery system
Mundipharma AB
Osteoarthritis
 
06/07
DTMPCA, NCT00564603: Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy

Completed
4
300
RoW
Dexamethasone Sodium Phosphate Injection, 0.9% Saline
Nanjing Medical University, HRSA/Maternal and Child Health Bureau
Postoperative Pain, Post Operative Analgesia, Patient-Controlled Analgesia, Abdominal Surgeries
11/07
11/07
2006-004698-86: Untersuchung der analgetischen Wirkung der AKupunktur bei Patienten mit Herpes zoster im Vergleich mit einer medikamentösen Standardtherapie-Comparison of acupuncture treatment to medical standard therapy in patients with acute herpes zoster

Ongoing
4
180
Europe
Gabapentin, Tramadol, Metamizol, paracetamol, Morphin, Metamizol
Schmerzambulanz Innenstadt der LMU
Patients suffering from pain due to a herpes zoster infection
 
 
NCT00692263 / 2007-004470-10: The Effect of Escitalopram on the Pharmacokinetics and Pharmacodynamics of Tramadol in Healthy Subjects

Completed
4
15
Europe
escitalopram and tramadol, Lexapro, Ultram, placebo, placebo and tramadol
University of Southern Denmark, H. Lundbeck A/S
Healthy
08/08
08/08
NCT00785603 / 2008-001516-20: Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study

Unknown status
4
12
NA
Paroxetine, Paroxetin, copyfarm, Paroxetin placebo, Tramadol, Nobligan
University of Southern Denmark
Depression, Pain
08/08
02/09
NCT00310908: Comparison Between Tramadol Hcl and Other Analgesics in the Treatment of Renal Colic

Completed
4
100
RoW
Tramadol Hcl
Hadassah Medical Organization, Grumental
Renal Calculus
02/09
02/09
NCT01019265: A Study Comparing Norspan Patch and Oral Tramadol

Completed
4
170
RoW
Buprenorphine 5mg, 10mg, 20mg vs Tramadol 100mg, Norspan patch, Buprenorphine transdermal system (BTDS)
Mundipharma Korea Ltd
Osteoarthritis
03/09
05/09
ChiCTR-TRC-09000385: Effect of tramadol administered at different time on postoperative shivering and patients' satisfactory.

Completed
4
150
 
administered tramadol 1.5mg/kg after induction ;administered tramadol 1.5mg/kg before skin closure ;Saline placebo
West China Hospital; SCHWARZ PHARMA, SCHWARZ PHARMA
postoperative shivering
 
 
NCT00733421 / 2008-000791-24: The Effect of Anti-inflammatory Analgesics on Pain Following Hallux Valgus Surgery

Completed
4
100
Europe
etoricoxib, Arcoxia, tramadol, Tiparol
Karolinska Institutet
Postoperative Pain
06/09
08/09
NCT00426647 / 2006-003322-28: Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip Knee and/or Lumbar Spine

Completed
4
120
Europe
Buprenorphine, Tramadol
Norpharma A/S, Mundipharma Finland
Osteoarthritis, Pain
07/09
08/09
NCT02436980: Premedication for ERCP With Midazolam or Tramadol

Completed
4
40
RoW
Tramadol, CONTRAMAL, Midazolam, DORMICUM
Karadeniz Technical University
Chronic Disease
09/09
12/09
NCT02246712: Influence of Diabetes on Tramadol Pharmacokinetics

Completed
4
30
RoW
Single oral dose of 100 mg racemic tramadol, Tramadol treament, Blood sampling, Tramadol pharmacokinetics, CYP2D6 phenotype, CYP2D6 phenotyping, CYP2D6 in vivo activity, CYP3A phenotype, CYP3A phenotyping, CYP3A in vivo activity, CYP2B6 genotype, Genotype of SNP 516G>T in CYP2B6
Universidade Estadual Paulista Júlio de Mesquita Filho, University of Sao Paulo
Neuropathic Pain, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
05/10
12/11
ChiCTR-TRC-11001467: Parcetamol/tramadol for Postoperative Pain of Benign Anorectal Diseases

Completed
4
120
 
Paracetamoland Tramadol Hydrochloride Tablets 400mg, po, qd, three days ;Placebo, 400mg, po, qd, three days
The sixth Affiliated Hospital, Sun Yat-sen University; The sixth Affiliated Hospital, Sun Yat-sen University, self-funding
hemorrhoids, anal fistulas or anal fissure
 
 
NCT01214941 / 2010-020617-82: Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Completed
4
12
Europe
Placebo, Ticlopidine, Ticlopidine and itraconazole
Turku University Hospital
Pharmacokinetics, Pharmacodynamics
12/10
12/10
NCT01526525: Perioperative Electroacupuncture on Postoperative Analgesia in Prostatectomy

Completed
4
70
Europe
Tramadol, Ketamine, Morphine, sedation, rescue analgesia, Parecoxib, paracetamol
G.Gennimatas General Hospital, Aristotle University Of Thessaloniki
Pain, Postoperative
09/11
02/12
NCT01443520 / 2011-003259-20: Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers

Completed
4
12
Europe
Placebo, Duloxetine, Venlafaxine
Turku University Hospital
Healthy
01/12
01/12
NCT00560443: RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child

Completed
4
133
Europe
ketorolac, tramadol
IRCCS Burlo Garofolo
Fracture, Pain
04/12
04/12
LIFT, NCT01416116 / 2010-023258-34: Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch

Completed
4
122
Europe, RoW
QUTENZA, capsaicin 8% patch, Lidocaine, Tramadol
Astellas Pharma Inc
or Peripheral Nerve Injury (PNI), Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN)
04/12
04/12
PTSM04APHP, NCT01345162 / 2009-011856-23: Assessment and Prevention of Acute Post-herniotomy Pain

Completed
4
200
Europe
Ketorolac postoperative, Toradol, postoperative Patrol, Patrol, intraoperative analgesia, Ketorolac, Tramadol
IRCCS Policlinico S. Matteo, University of Pavia
Hernia
05/12
05/12
NCT01558622: Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication

Unknown status
4
72
RoW
dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride, dexketoprofen trometamol + tramadol hydrochloride, dexketoprofen trometamol + pethidine hydrochloride, vitamin c
Kavaklıdere Umut Hospital
Laparoscopic Nissen Fundoplication
05/12
 
ChiCTR-TRC-12002870: Preventive effects of parecoxib sodium on postoperative shivering

Completed
4
120
 
parecoxib sodium 40 mg ;tramadol 2mg.kg-1 ;saline
Mianyang Central Hospital, Sichuan, China; Level of the institution:, Self-financing
postoperative shivering
 
 
NCT01116531: Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin

Withdrawn
4
0
Europe
Tramadol, Duloxetine, Pregabalin
Turku University Hospital, University of Helsinki
Diabetic Polyneuropathy, Postherpetic Neuralgia
12/12
12/12
TOPCAB, ChiCTR-TRC-12002125: Application of Tramadol Analgesia after Off-Pump Coronary Artery Bypass Graft Surgery

Completed
4
52
 
tramadol as postoperative analgesia ;sufentanil as postoperative analgesia
Department of Anesthesiology, Peking University People's Hospital; Department of Anesthesiology, Peking University People's Hospital, none
Off-pump Coronary Artery Bypass Graft Surgery postoperative Analgesia
 
 
NCT02518438: The Analgesic Efficacy of Wound Infiltration With Tramadol

Completed
4
60
RoW
Tramadol, Placebo (0,9% saline solution)
Yeditepe University Hospital
Postoperative Pain
03/13
05/13
NCT01943760: Tamadol Wound Infiltration in Children Under Inguinal Hernioplasty

Completed
4
40
RoW
tramadol, tramal, 0.9% saline
Federal University of São Paulo
Children, Inguinal Hernia
09/13
09/13
ACTRN12611001220954: Tramadol vs. Morphine for refractory pain in the recovery room

Completed
4
100
 
Kelly Byrne, Anaesthetic department, Waikato hospital
Post-operative pain
 
 
ChiCTR-TRC-13004194: The Comparison of The Effect of Postoperative Early Analgesia with Tramadol, Sufentanil and Dezocine on Thyroid Surgery

Completed
4
90
 
sufentanil ;tramadol ;decocine
Third Affiliated Hospital of Harbin Medical University; Third Affiliated Hospital of Harbin Medical University, study drugs are provided by the Third Affiliated Hospital of Harbin Medical University
The Analgesic of Research
 
 
PENTRA, NCT01887951: Penthrox Versus Tramadol for SCDF

Completed
4
380
RoW
Penthrox Inhaler, Tramadol Injection
Singapore General Hospital
Acute Pain
08/14
10/15
NCT02110966: Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis

Completed
4
56
RoW
Mepivacaine, Dentocaín, Mepivacaine plus Tramadol, Tradol
Daniel Chavarría Bolaños
Symptomatic Irreversible Pulpitis
10/14
10/14
2009-016998-15: Effect of terbinafine and itraconazole on the pharmacokinetics and pharmacodynamics of oral tramadol: A three-phase randomized balanced cross-over study in healthy volunteers

Completed
4
12
Europe
Tablet, Capsule, hard, Lamisil, Sporanox, Tramal
University of Turku
Acute postoperative pain and chronic pain syndromes
 
 
NCT02291705: Ultrasound-guided Rectus Sheath Block In Children

Completed
4
40
RoW
rectus sheath block, Tramadol
Cukurova University
Postoperative Pain
11/14
11/14
ChiCTR-ONRC-13003785: A clinical observative study concerning Celebrex administration impact on serological inflammatory factor, skin temperature and knee function after total knee arthroplasty

Completed
4
120
 
Tramadol hydrochloride sustained release tablets ;celecoxib capsule
The First Affiliated Hosipital of Guangzhou University of Chinese Medicine; None, self-financing
knee osteoarthritis
 
 
2015-000992-28: A comparison of the severity of acute pain and the frequency of chronic pain after post-operative analgesia of lower and higher intensity following surgical emptying of the axillary gland in breast cancer patients in relation to the pharmacogenomics in the metabolism of tramadol – a prospective, double blind, randomised clinical trial Primerjava jakosti akutne in pogostosti kronične bolečine po šibkejši in močnejši pooperativni analgeziji po operaciji izpraznitve pazdušnih bezgavk zaradi raka dojke glede na farmakogenomiko presnove tramadola – prospektivna dvojno slepa randomizirana raziskava

Ongoing
4
120
Europe
Doreta, Film-coated tablet, Doreta
Krka, d.d., Novo mesto, Krka, d.d., Novo mesto
Acute pain after surgical emptying of the axillary gland in breast cancer patients. Bolečina po operaciji raka dojke z izpraznitvijo pazdušnih bezgavk ., Acute pain after surgical emptying of the axillary gland in breast cancer patients. Bolečina po operaciji raka dojke z izpraznitvijo pazdušnih bezgavk ., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
NCT01930318: Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance After Gastrointestinal Laparoscopic Surgery

Unknown status
4
164
RoW
parecoxib, COX-2 selective inhibitors
Jinling Hospital, China, National Natural Science Foundation of China
Gastrointestinal Cancer
08/15
09/15
NCT02850211: A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair

Completed
4
180
RoW
Celecoxib, Celebrex, Ibuprofen, Carol-F, Tramadol, Tridol
Seoul National University Bundang Hospital
Rotator Cuff Tear
11/15
11/15
NCT02484859: Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery

Completed
4
88
RoW
Remifentanil, Ultiva, Tramadol, Contramal, Metoprolol, Beloc
Recep Tayyip Erdogan University
Nasal Polyps
12/15
02/16
2006-001951-36: Perioperative Analgesie in der Gefäßchirurgie

 
4
200
Europe
Oxycodone, Tramadol, Oxycontin, Tramal, Oxycontin, Tramal
Medical University of Vienna
peripheral vascular disease, inclusion criteria: elective vascular surgery, age 30 to100years; male and female; exclusion Criteria: amaurosis, insufficient language skills, permanent opioid medication (morphin oral equivalent 80mg per day), permanent medication of tricyclic antidepressivs, history of adverse events to opioid medication
 
04/08
2007-001006-24: Effet du tramadol sur la sensibilisation centrale à la douleur chez le sujet volontaire sain

Ongoing
4
12
Europe
contramal, contramal
CHU Gabriel Montpied
volontaires sains
 
 
2007-002854-52: Postoperativ smärta och analgetika konsumtion efter visdomstandskirurgi – en kontrollerad randomiserad enkelblind jämförelse med och utan tramadol vid intravenös midazolamsedering.

Completed
4
75
Europe
Tramadol, Tramadol Hexal, Tramadol Hexal
Folktandvården, Landstinget Dalarna
Problemställning:Jämföra postoperativ smärta och analgetikakonsumtion mellan två rutinmetoder för sedering med och utan intravenös analgesi.
 
10/09
2009-013061-26: Efficacy, safety, tolerability and pharmacokinetics of concomitant administration of tramadol with duloxetine or pregabalin: a randomized controlled flexible-dose study in patients with neuropathic pain

 
4
40
Europe
Tramal retard, Lyrica, Cymbalta, Tramal retard, Lyrica, Cymbalta
University of Turku
G53.0 Vyöruusun jälkeinen hermosärkyG63.2 Diabeteksen monihermosairaus
 
09/11
2013-004741-16: Effect of the administration of tramadol on the success of the inferior anesthetic blocking technique in mandibular molars with acute inflammation Efecto de la administración de tramadol sobre el éxito de la técnica anestésica de bloqueo mandibular en molares inferiores con inflamación aguda

Ongoing
4
30
Europe
TRAMADOL NORMON 100 mg/2 ml Solución inyectable EFG, TRAMADOL NORMON 100 mg/2 ml Solución inyectable EFG
Ana de Pedro Muñoz, Ana de Pedro Muñoz
Anesthetic failure of the inferior alveolar nerve block in mandibular molars with irreversible pulpitis Fracaso de la anestesia del bloqueo del nervio dentario inferior en molares mandibulares con pulpitis irreversible aguda
 
 
NCT01916915: Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section

Completed
4
65
RoW
Tramadol infusion via wound catheter, Levobupivacaine
Ufuk University
Pain, Postoperative
02/16
03/16
NCT02327923: Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy

Completed
4
90
RoW
Lidocaine, Lignocaine, Xylocaine, Esmolol, Paracetamol, Xylocaine, Propofol, Fentanyl, Vecuronium, Atropine, Ephedrine, Morphine, Ketorolac, Ondansetron, Bupivacaine, Tramadol, Neostigmine, Glycopyrrolate
B.P. Koirala Institute of Health Sciences
Gall Stone Disease
02/16
04/16
NCT02412930: Comparative Study of Ultrasound-guided Paravertebral Block Versus Intravenous Tramadol in Percutaneous Nephrolithotomy

Completed
4
53
RoW
Ultrasound-guided Paravertebral Block, Group Tramadol, Bupivacaine, Ultrasound
Cukurova University
Postoperative Pain
03/16
04/16
NCT02361567: Comparison of Tramacet Versus Percocet in Post Surgical Patients

Completed
4
160
Canada
Tramacet, tramadol/acetominophen, Percocet, oxycodone/acetominophen
Lawson Health Research Institute
Post Operative Pain
03/16
03/16
NCT02445599: Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Completed
4
3
Europe
Diclofenac, Diclofenac Stada 100 mg retard, Midazolam, Dormicum 5mg/ml, Atropine, Atropine 1 mg/ml, bucain + fentanyl, Nalbuphine, Nubain 20mg/2ml, Neodolpasse 75 mg/ 250ml, Metamizole-sodium, Algopyrin 2g/2ml, Tramadol, Contramal 100mg/2ml
University of Debrecen
Pain, Inadequate or Impaired Respiratory Function
04/16
04/16
2015-004482-88: Randomized clinical trial to compare the safety and effectiveness of metamizol, ibuprofen and tramadol combined with paracetamol in the treatment of pain after a surgical intervention to repair a femur fracture in patients >= 80 years admitted Convalescence Unit Ensayo clínico aleatorizado para comparar la seguridad y efectividad de metamizol, ibuprofeno y tramadol combinados con paracetamol, en el tratamiento de dolor después de una intervención quirúrgica por fractura del fémur en pacientes de >= 80 años ingresados en la Unidad de Convalecencia

Ongoing
4
180
Europe
Ibuprofeno, metamizol, Tramadol, Tablet, Capsule, Oral drops, solution
Fundació Parc Taulí, Fundació Parc Taulí
The medical condition being studied is post surgical pain following surgery for femur fracture in patients ? 80 years old La condición médica estudiada es el dolor postquirúrgico después de cirugía por fractura de fémur en pacientes ? 80 años., Pain after surgery for femur fracture in patients ? 80 years old Dolor después de la cirugía por fractura de fémur en pacientes ? 80 años., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
ATLAS, NCT02851394: Advantage of Tramadol in Local Analgesia Post-Sternotomy

Completed
4
160
Europe
Levobupivacaine, levobupivacaine, tramadol
Centre Hospitalier Universitaire Dijon
Heart Surgery Via Sternotomy, Post-operative Analgesia
05/16
10/16
ChiCTR-IPR-16008261: Tramadol and sufentanil treatment in controlled analgesia after cesarean section Pharmacoeconomic Evaluation

Recruiting
4
240
 
Use of tramadol hydrochloride controlled analgesia ;Use of sufentanil controlled analgesia
Urumqi People's Liberation Army General Hospital; West China School of Pharmacy Sichuan University, Lateral research funds
Cesarean section
 
 
NCT02416804: Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery

Completed
4
69
RoW
Buprenorphine, Norspan, Tramadol, Zytram
Seoul National University Hospital
Spinal Stenosis, Pain, Postoperative
07/16
02/17
ChiCTR-PPD-16009008: Tramadol pretreatment for reducing etomidate resulted myoclonus and severity

Recruiting
4
30
 
tramodol pretreatment
People's Hospital, Wuhan University; Renmin Hospital of Wuhan University, self-raised
myoclonus induced by etomidate
 
 
ChiCTR-IPR-16008995: Tramadol and hydromorphone treatment in controlled analgesia after cesarean section Pharmacoeconomic prospective clinical observational study

Recruiting
4
240
 
Use of tramadol hydrochloride controlled analgesia ;Use hydromorphone controlled analgesia
XinQiao hospital, Third Military University; West China School of Pharmacy Sichuan University, Lateral research funds
Cesarean section
 
 
NCT02076893: Postoperative Tramadol/Gabapentin/Ibuprofen Versus Tramadol/Placebo/Ibuprofen

Terminated
4
64
US
gabapentin, Neurontin, Tramadol, Ultram, Ibuprofen, Advil, Motrin, Placebo
Children's Hospitals and Clinics of Minnesota
Pain
02/17
02/17
NCT02777970 / 2015-004152-22: Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar

Completed
4
654
Europe
Tramadol Hydrochloride/Dexketoprofen Trometamol, Tramadol Hydrochloride/Paracetamol, Placebo
Menarini Group
Acute Pain
02/17
02/17
IVPARACET, NCT02248493: Intravenous Paracetamol for Postoperative Pain

Completed
4
54
Europe
Paracetamol, Acetaminophen, Placebo (for paracetamol), 0.9% sodium cloride solution, Normal saline solution, Izotonic saline solution, Ketoprofen, Ketonal, Tramadol, Tramal, Morphine
Lithuanian University of Health Sciences
Pain, Postoperative, Recovery of Function, Child
03/17
03/17
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE)

Ongoing
4
450
Europe
Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten
Leiden University Medical Center, Leiden University Medical Center
Adverse drug reactions, Side-effects, Not possible to specify
 
 
ChiCTR-OPC-17011315: Comparison of different analgesic strategies in elderly patients with spinal chronic muscle skeletal pain

Not yet recruiting
4
330
 
Buprenorphine Transdermal patch ;Tramadol Hydrochloride Sustained Release Tablets ;NSAIDs
Peking Union Medical College Hospital; Peking Union Medical College Hospital, raise independently
Spinal chronic muscle skeletal pain
 
 
NCT03067103: Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain

Unknown status
4
108
RoW
Tramadol, group 1, Ketamine, Group 2, Placebos, Group 3
Universidade Federal de Goias
Sleep Disorder; Breathing-Related, Pain, Postoperative, Child, Only
07/17
05/19
ChiCTR-IIR-17011043: Comparsion of postoperative analgesic effect between Tramadol and Hydromorphone in repeated cesarean section

Recruiting
4
106
 
Tramadol ;Hydromorphone
Xinqiao Hospital, Third Military Medical University; Xinqiao Hospital, Xinqiao Hospital
Postoperative pain
 
 
Jaydess, NCT02706509: Pain Management Associated With the Insertion of ® in Nulliparous Women

Unknown status
4
100
NA
Tramadol, ultram, Verbal anesthesia, Jaydess
Meir Medical Center
IUD Insertion Complication
09/17
12/18
NCT03126084: Postoperative Effects of TAP Block Versus QLB Type 2 Block

Completed
4
90
RoW
Acetaminophen, Postoperative routine analgesia, 0.25% Bupivacaine, Transversus abdominis plane block, 0.5% Bupivacaine+Glucose, Subarachnoid Block, Tramadol HCl, Postoperative Salvage Analgesia, Inguinal Hernia Repair, Quadratus lumborum block type 2
Bozyaka Training and Research Hospital
Inguinal Hernia, Postoperative Pain
11/17
11/17
NCT02958566: Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Unknown status
4
80
US
Acetaminophen, Tylenol, Ofirmev, Gabapentin, Neurontin, Orphenadrine, Norflex, Lidocaine, Marcaine, Ketamine, Methadone, Tramadol, Ultram, Ketorolac, Toradol, Morphine Sulfate, Fentanyl, Dilaudid, Hydrocodone-Acetaminophen Tab 5-325 MG, Norco, HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
University of Illinois College of Medicine at Peoria
Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
12/17
12/18
NCT02964416: Single Dose Tramadol Effect on Extubation Response and Quality of Emergence Post-supratentorial Intracranial Surgery

Completed
4
80
RoW
Injection Tramadol, Tramal, placebo, normal saline
Aga Khan University
Brain Neoplasm
03/18
12/18
ChiCTR1800014986: Comparsion of analgesic effect on visceral pain between tramadol and sufentanil after repeated caesarean section

Recruiting
4
126
 
PCIA tramadol ;PCIA Sufentanil
The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology; The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology
Postoperative pain
 
 
NCT03622489: Comparing Protocols for Analgesia Following Elective Cesarean Section

Unknown status
4
120
RoW
Acetaminophen, Ibuprofen 400 mg, Dipyrone, Tramadol, Tramadex, Morphine, Tramal
Wolfson Medical Center
Postoperative Pain, Post-Cesarean Section
08/18
08/18
NCT03694873: Oral Tramadol Versus Oral Celecoxib for Post-perineal Repair Analgesia

Unknown status
4
200
NA
Tramadol Hydrochloride, Celecoxib 200mg
Cairo University
Perineal Pain
12/18
12/18
NCT03309163: Effect of Tramadol in Prevention of Postpartum Depression

Completed
4
1230
RoW
Tramadol, Hydromorphone, Ropivacaine (Epidural analgesia)
Xinqiao Hospital of Chongqing
Caesarean Section
06/19
08/19
MAST, NCT03472469: Trial: Multi-modal Analgesic Strategies in Trauma

Completed
4
1561
US
Acetaminophen IV/PO, Acetaminophen PO, Ketorolac, Celebrex, Naproxen, Tramadol, Pregabalin, Gabapentin, Lidocaine, Opioids, Regional anesthesia
The University of Texas Health Science Center, Houston, National Center for Advancing Translational Science (NCATS)
Nonspecific Pain Post Traumatic Injury
07/19
07/19
TSSPC, NCT02595190: Treatment of the Symptomatic Sacral Perineurial Cysts

Unknown status
4
96
RoW
sacral canal cyst microscopic tamponade, gabapentin + tramadol, resting state functional magnetic resonance imaging (rfMRI)
Southwest Hospital, China
Pain
03/20
03/20
TramIsch, NCT03477851: Tramadol Simultaneously With Sciatic Nerve Block for Calcaneus Fracture Osteosynthesis

Completed
4
40
Europe
Tramadol Hydrochloride, Tramadol i.m., Placebo, 0,9%NaCl i.m.
Medical University of Warsaw
Foot Fracture, Pain, Acute
06/20
12/20
Shoulder1, NCT04110665: Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery

Unknown status
4
200
Europe
Tramadol, Paracetamol, Ketoprofene, Nefopam 20 MG/ML, Morphine Sulfate, Oxycodone 20mg
Centre Hospitalier Universitaire de NÄ«mes
Tendon Injuries
09/20
12/20
TROXAT, NCT03454217: Impact of Tramadol and Oxycodone on Sleep Apnea

Completed
4
60
Europe
Oxycodone, Tramadol
Centre Hospitalier Universitaire Vaudois
Sleep Apnea
09/20
09/20
NCT04445857: Efficacy of Coadministration of Calcitonin and Hyperbaric Bupivacaine on Spinal Anesthesia in Tramadol-abuse Patients

Completed
4
90
RoW
Calcitonin presented as Miacalcic® ampoules 100 IU/ml (1ml), normal saline (NS)
Ain Shams University
Analgesia
01/21
01/21
NCT04521556: Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.

Completed
4
80
RoW
Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, Epidural analgesia with morphine and ropivacaine, General anesthesia, Continuous intravenous analgesia, Continuous tramadol analgesia
University Hospital of Split
Anesthesia, Anesthesia Recovery Period, Nephrectomy, Patient Satisfaction, Postoperative Period, Quality of Life, Analgesia, Epidural
04/21
06/21
NCT04745273: Interaction Between Tramadol and Ondansetron

Completed
4
60
RoW
Ondansetron 4 MG (Kemoset 4mg), Kemoset, Salin solution
Acibadem University
Cholecystectomy, Laparoscopic
06/21
06/21
2021-001238-21: Gender differences in pain medicine: from genetics to healthcare. Diferencias de género en medicina del dolor: de la genética a la atención sanitaria.

Ongoing
4
500
Europe
Morphine, Fentanyl, Tramadol, Compressed lozenge, Transdermal patch, Capsule, hard
Institute of Health and Biomedical Research of Alicante, Instituto de Salud Carlos III
The medical condition to be evaluated is the analgesic response of people with chronic low back pain who are going to be treated with opioids, guided by omics sciences (pharmacogenetics, epigenetics and metabolomics). La condición médica a evaluar es la respuesta analgésica de las personas con dolor crónico causado por lumbalgia que van a ser tratadas con opioides, cuyo tratamiento será guiado por las ciencias ómicas (farmacogenética, epigenética y metabolómica)., The medical condition to be evaluated is the analgesic response of people with chronic low back pain who are going to be treated with opioids, guided by genetics information. La condición médica a evaluar es la respuesta analgésica de las personas con dolor crónico causado por lumbalgia que van a recibir tratamiento con opioides, guiado según su información genética., Health Care [N] - Health Care Quality, Access, and Evaluation [N05]
 
 
ChiCTR2000038350: Study on the effectiveness of different ways to prevent the adverse reactions of Hemabate during cesarean section under NICaS monitoring

Recruiting
4
200
 
pretreatment with sufentanil 0.1 ug/kg ;Intravenous pump injection of dexmedetomidine 0.8 ug /kg/h pretreatment; pretreatment with tramadol 0.15 mg/kg ;pretreatment with 0.9% sodium chloride solution
Chongqing Health Center for Women and Children; Chongqing Health Center for Women and Children, Hospital Project 2019YJMS07
Anesthesia for Cesarean Section
 
 
NCT05956275: USG-Guided Infiltration Popliteal Artery Capsule Knee Block Versus Adductor Canal Block Application as Postoperative Analgesia

Completed
4
20
RoW
Tramadol, Morfin
Siirt Training and Research Hospital, Abant Izzet Baysal University
Postoperative Pain
10/21
10/21
NCT05500677: Lidocaine Spray for Pain Control in Rib Fractures

Completed
4
48
RoW
Lidocaine topical, Tramadol hydrochloride, Fentanyl citrate
Ankara City Hospital Bilkent
Rib Fractures, Analgesia
11/21
11/21
NCT05569031: Treatment of Withdrawal Symptoms and Prevention of Relapse in Patients With Tramadol Abuse

Completed
4
52
RoW
Venlafaxine, Lofexidine
Zagazig University
Opiate Withdrawal Syndrome
12/21
06/22
NCT04766996: PROUD Study - Preventing Opioid Use Disorders

Terminated
4
57
US
Guided mindfulness exercises, Self-administered aromatherapy, Baby aspirin, Tylenol/Acetaminophen, Pregabalin, Prednisone, Meloxicam, Prilosec, Tramadol, Voltaren, Zofran, Pepcid, Reglan, Versed, Lidocaine, Propofol, Ancef, Tranexamic Acid (TXA), Decadron, Bupivacaine hydrochloride, Toradol
Emory University
Anesthesia, Opioid Use
12/21
12/21
NCT05488925: Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.

Completed
4
120
RoW
Vitamin E, Diclofenac Sodium, Piroxicam, Tramadol
Farjad Zafar
Symptomatic Irreversible Pulpitis
02/22
02/22
Dante, NCT05170841 / 2019-003656-37: Study Evaluating Dexketoprofen Trometamol/Tramadol Hydrochloride Analgesic Efficacy in Acute Low Back Pain

Completed
4
544
Europe
Dexketoprofen Trometamol 25 mg/Tramadol Hydrochloride 75 MG, Skudexa, Tramadol Hydrochloride 100 MG, Tramadol, Placebo
Menarini International Operations Luxembourg SA
Low Back Pain
05/22
05/22
ChiCTR2100046325: The study of tramadol combined with atropine to improve the comfort of outpatient diagnostic hysteroscopy

Recruiting
4
400
 
Tramadol capsule 100mg orally 1 hour before surgery, atropine 0.25mg intramuscular 10 minutes before surgery ;No preconditioning was done before surgery ;Tramadol 100mg orally 1 hour before surgery ;Atropine 0.25mg was intramuscular injected into buttocks 10 minutes before surgery
Shandong First Medical University Affiliated Provincial Hospital; Shandong First Medical University Affiliated Provincial Hospital, self-financing
Outpatient diagnostic hysteroscopy for pain
 
 
NCT05418504: Study of Tramadol Addiction Impact on Dental Anesthesia Success Among Algerian Males

Recruiting
4
400
RoW
Dental anesthesia
Future University in Egypt
Dental Procedure
08/22
08/22
NCT04694300: OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients

Completed
4
30
US
Naproxen, Aleve, Acetaminophen, Extra Strength Tylenol, Tramadol, Ultram
Hersh, Elliot V., DMD, MS, PhD, University of Pennsylvania
Osseointegrated Dental Implantation, Pain, Acute
08/22
08/22
NCT04391855: Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery

Completed
4
72
Europe
Tramadol with ropivacaine, TR, Dexmedetomidine with ropivacaine, DR, Magnesium with ropivacaine, MR, Ropivacaine plus normal saline, R
Aristotle University Of Thessaloniki
Analgesia, Pain, Postoperative, Spinal Stenosis, Spinal Disease
11/22
12/22
2022-003273-37: Opioid-Free analgesia in Intensive Care Unit

Not yet recruiting
4
50
Europe
Paracetamol, Remifentanil, Ketamine, Chlorhydrate de néfopam, Chlorhydrate de tramadol, Solution for infusion, Powder for solution for injection/infusion, Solution for injection, Solution for injection/infusion
CHU de NIMES, NIMES UNIVERSITY HOSPITAL
Intensive care patient requiring sedation and analgesia for invasive mechanical ventilation, Intensive care patient requiring sedation and analgesia for invasive mechanical ventilation, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
NCT05183334: Combined On-demand Sildenafil Citrate and Tramadol Hydrochloride for Treatment of Premature Ejaculation

Not yet recruiting
4
160
NA
Sildenafil 50 mg, sildanafil, Placebo, no drug, Tramadol Hydrochloride 100 MG, tamol
Assiut University
Premature Ejaculation
12/22
12/22
ChiCTR2200062848: Esketamine combined with tramadol for patient controlled intravenous analgesia after cesarean section: a randomized control trial

Not yet recruiting
4
188
 
Postoperative analgesic pump formula of the control group is butorphanol tartrate 5 mg+tramadol hydrochloride 400mg, diluted to 100 mL with normal saline ;The analgesic pump formula in the experimental group is esketamine hydrochloride 50 mg+tramadol hydrochloride 40 mg, diluted to 100 mL with normal saline
The People's Hospital of Pizhou; The People's Hospital of Pizhou, Anesthesiology Department of the People's Hospital of Pizhou
Postoperative pain
 
 
ChiCTR2000041419: Study on analgesic effect of Tramadol Hydrochloride injection in patients with tongue carcinoma after surgery

Recruiting
4
200
 
Intramuscular injection of tramadol hydrochloride was performed
West China Stomatological Hospital of Sichuan University; West China Stomatological Hospital of Sichuan University, Hospital
Tongue cancer
 
 
NCT04551833: Tramadol Versus Dexamethasone as Adjuvant to Levobupivacaine Supraclavicular Block

Not yet recruiting
4
60
NA
Levobupivacaine
Assiut University
Regional Anesthesia
04/23
05/23
 

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