ChiCTR-ONC-10000894: Nilotinib plus multi-agent chemotherapy for philadelphia chromosome-positive acute lymphoblastic leukemia |
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| Recruiting | 1 | 30 | | Nilotinib plus multi-agent chemotherapy | Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences; Novartis pharmaceutical co., Ltd, Novartis pharmaceutical co., Ltd | Philadelphia chromosome-positive acute lymphoblastic leukemia | | | | |
| Completed | 1 | 326 | Europe, Japan, US, RoW | Asciminib (ABL001), ABL001, Nilotinib, Imatinib, Dasatinib | Novartis Pharmaceuticals | Chronic Myelogenous Leukemia, Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia | 06/21 | 03/23 | | |
NCT04205903: Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer |
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| Recruiting | 1 | 20 | US | Nilotinib, AMN 107 Base Form, Nilotinib Hydrochloride Monohydrate, AMN107, Nilotinib Monohydrochloride Monohydrate, Tasigna, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Placebo, placebo therapy, PLCB, sham therapy, Questionnaire Administration | Ohio State University Comprehensive Cancer Center, National Cancer Institute (NCI) | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8 | 01/24 | 01/24 | | |
NCT04903119: Nilotinib Plus Dabrafenib/Trametinib in Metastatic Melanoma |
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| Recruiting | 1 | 15 | US | Nilotinib 100mg, Nilotinib 200mg, Nilotinib 300mg, Nilotinib 400mg, Dabrafenib, Trametinib | Jill M Kolesar, Novartis, National Cancer Institute (NCI) | Metastatic Melanoma, BRAF Gene Mutation | 12/26 | 03/27 | | |