| Proellex (telapristone) / AbbVie |
| Completed | 1 | 21 | US | 25 mg Proellex, CDB-4124, Telapristone acetate, 50 mg Proellex | Repros Therapeutics Inc. | Healthy | 07/07 | 07/07 | | |
| Completed | 1 | 12 | US | Proellex 25 mg formulation A, Telapristonee acetate, Proellex 25 mg formulation B, Telapristone acetate | Repros Therapeutics Inc. | Healthy | 04/08 | 04/08 | | |
NCT00619385: A Safety and Pharmacokinetic Study of Proellex® |
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| Completed | 1 | 25 | US | Proellex, Telapristone acetate | Repros Therapeutics Inc. | Healthy | 09/08 | 10/08 | | |
NCT00741468: Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects |
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| Completed | 1 | 18 | US | Proellex, Telapristone acetate, CYP1A2 probe, Caffeine (200 mg), CYP2C9 probe, Tolbutamide (250 mg), CYP2C19 probe, Omeprazole (20 mg), CYP2D6 probe, Dextromethorphan (30 mg), CYP3A4 probe, Midazolam (2mg) | Repros Therapeutics Inc. | Drug Interactions | 09/08 | 10/08 | | |
NCT00749879: Crossover Study of the Safety and PK Properties of Proellex® |
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| Completed | 1 | 17 | US | Proellex, Telapristone acetate | Repros Therapeutics Inc. | Pharmacokinetics | 10/08 | 10/08 | | |
NCT00741273: Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults |
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| Completed | 1 | 16 | US | Proellex, Telapristone acetate | Repros Therapeutics Inc. | Impaired Liver Function | 05/09 | 06/09 | | |
NCT00881062: Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females |
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| Completed | 1 | 6 | US | Proellex, Telapristone acetate | Repros Therapeutics Inc. | ABSORPTION, METABOLISM, EXCRETION | 05/09 | 06/09 | | |
NCT00881608: Study to Evaluate Menses Induction in Women Administered Proellex |
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| Terminated | 1 | 11 | US | Placebo, Dummy, Proellex, Telapristone acetate | Repros Therapeutics Inc. | Amenorrhea | 08/09 | 08/09 | | |
NCT02141061: Comparison of Two Formulations of Proellex for Oral Administration |
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| Completed | 1 | 12 | US | Telapristone Acetate, Proellex 12 mg Formulation A, Proellex, Telapristone Acetate, Proellex 12 mg Formulation B | Repros Therapeutics Inc. | Healthy | 06/14 | 06/14 | | |
