| fosaprepitant / Generic mfg. |
OFFER, NCT04536558: Olanzapine Plus Fosaprepitant Standard Antiemetic Therapy in the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients Receiving High Emetic Risk Multi-day Chemotherapy: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study |
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| Not yet recruiting | 3 | 352 | RoW | olanzapine plus fosaprepitant-based triple regimen, placebo plus fosaprepitant-based triple regimen | Sun Yat-sen University, Jiangsu Hansoh Pharmaceutical Co., Ltd. | Solid Tumor Patients Receiving High Emetic Risk Multi-day Chemotherapy | 02/21 | 03/21 | | |
A221602, NCT03578081: Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy |
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| Completed | 3 | 690 | US, RoW | Palonosetron Hydrochloride, Ondansetron Hydrochloride, Dexamethasone, Fosaprepitant Dimeglumine, Olanzapine, Placebo | Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI) | Malignant Neoplasm | 11/21 | 05/23 | | |
NCT04873284: Comparative Study of Fosaprepitant and Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Caner Patients |
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| Not yet recruiting | 3 | 120 | RoW | fosaprepitant, aprepitant, Granisetron plus dexamethasone | Shanghai Children's Medical Center | Chemotherapy Induced Nausea and Vomiting, Pediatric Cancer Patients | 12/21 | 12/21 | | |
NCT04912271: Granisetron Transdermal Patch for Prophylaxis of Delayed CINV |
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| Not yet recruiting | 3 | 140 | NA | Granisetron transdermal patch, sancuso, Palonosetron, Aprepitant, Fosaprepitant, Dexamethasone | Fudan University | Chemotherapy-induced Nausea and Vomiting (CINV) | 06/22 | 12/23 | | |
NCT05509634: Clinical Study of HR20013 for Injection in Patients With Malignant Solid Tumors |
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| Completed | 3 | 754 | RoW | HR20013 for injection；dexamethasone, fosaprepitant dimeglumine for injection；palonosetron hydrochloride injection；dexamethasone | Fujian Shengdi Pharmaceutical Co., Ltd. | Prevention of Nausea and Vomiting Caused by Highly Emetogenic Chemotherapy | 06/23 | 08/23 | | |
NCT06200168: Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer |
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| Recruiting | 3 | 370 | RoW | Electroacupuncture, Standard antiemetic treatment, Sham electroacupuncture | Jiuda Zhao | Electroacupuncture, Olanzapine-contained Four-drug Antiemetic, Nausea and Vomiting | 10/26 | 12/26 | | |
NCT05244577: Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer |
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| Recruiting | 3 | 75 | RoW | Olanzapine Tablets, Olanzapine, Placebo | Shi Yanxia | Olanzapine, CINV, Testicular Cancer by AJCC V6 and V7 Stage, Cisplatin | 12/23 | 03/24 | | |
HELEN-009, NCT05242874: Fosaprepitant , Tropisetron and Olanzapine for the Prevention of Nausea and Vomiting in Patients With Breast Cancer |
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| Completed | 3 | 442 | RoW | Fosaprepitant , Tropisetron and Olanzapine, Standard antiemetic therapy without dexamethasone, Fosaprepitant , Tropisetron, Dexamethasone and Olanzapine, Standard antiemetic therapy | Henan Cancer Hospital | Chemotherapy-induced Nausea and Vomiting | 08/23 | 08/23 | | |
NCT06282211: the Efficacy and Safety of Ondansetron Oral Soluble Pellicles |
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| Recruiting | 3 | 184 | RoW | Ondansetron Oral Soluble Pellicles, Aiqisu | The First Affiliated Hospital of Xinxiang Medical College | Nausea and Vomiting | 03/24 | 12/24 | | |
NCT04503668: Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients |
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| Terminated | 3 | 62 | US | Ondansetron, Dexamethasone, Neurokinin-1 Receptor Antagonist (NK1-RA), Fosaprepitant, Olanzapine, Zyprexa, Compazine | University of Michigan Rogel Cancer Center | Gynecologic Cancer | 01/24 | 03/24 | | |
NCT05564286: Triple Antiemetic Regimen for Chemoradiotherapy in Cervical Cancer or Nasopharyngeal Cancer |
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| Completed | 3 | 116 | RoW | Fosaprepitant, shanqi, tropisetron, luoting, Dexamethasone, xiluoan | Shantou University Medical College | Cervical Cancer, Nasopharyngeal Cancer, Chemotherapy-induced Nausea and Vomiting, Radiation-Induced Nausea and Vomiting, Antiemetic | 07/23 | 08/23 | | |
| Not yet recruiting | 2/3 | 250 | US | Fosaprepitant 150 mg, Ondansetron 4 mg | Montefiore Medical Center | Nausea and Vomiting, Nausea, Vomiting | 12/24 | 12/24 | | |
