| pregabalin / Generic mfg. |
2021-004417-40: The effect of pregabalin in the treatment of acute post-operative peripheral neuropathic pain – a pilot study |
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| Not yet recruiting | 4 | 50 | Europe | Lyrica | Helse Bergen HF, Helse Bergen HF | acute post-operative peripheral neuropathic pain, acute post-operative peripheral neuropathic pain, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT06367998: Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair |
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| Not yet recruiting | 4 | 76 | NA | Pregabalin, Lyrica | The Catholic University of Korea, Viatris Korea | Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain | 05/25 | 05/26 | | |
NCT05478382: Pregabalin is an Effective Treatment for Acute Postoperative Pain Following Spinal Surgery Without Major Side Effects |
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| Not yet recruiting | 4 | 132 | NA | Pregabalin 25 MG, Placebo | Ajou University School of Medicine, HK inno.N Corporation | Postoperative Pain, Pregabalin, Spine Surgery, Adverse Reaction to Pregabalin | 12/25 | 12/25 | | |
| Completed | 3 | 140 | Europe | Capsaicin, qutenza EU/1/09/524/001, Pregabalin, Lyrica | Institut Cancerologie de l'Ouest, Grünenthal GmbH | Breast Cancer Patient | 11/22 | 11/22 | | |
LOBUXALIII, NCT05324059: Efficacy and Safety of Pregabalin/Tramadol Combination Versus Pregabalin in Acute Pain of Neuropathic Origin |
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| Completed | 3 | 110 | RoW | Pregabalin 75mg/ Tramadol 50 mg, LOBUXAL, Pregabalin 75mg, Pregabalin | Laboratorios Silanes S.A. de C.V. | Neuropathic Pain | 04/23 | 04/23 | | |
NCT04666714: Efficacy and Safety of Praga Formulation in the Treatment of Neuropathic Pain |
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| Recruiting | 3 | 136 | RoW | Praga formulation, Placebo pregabalin 75mg, Placebo Pregabalin 150mg, Pregabalin 75mg, Pregabalin 150mg, Placebo Praga formulation | EMS | Neuropathic Pain | 12/24 | 08/25 | | |
NCT06516094: Efficacy and Safety in the Combination of Celecoxib / Pregabalin / Vitamin B for Low Back Chronic Pain |
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| Recruiting | 3 | 192 | RoW | Celecoxib+Pregabalin+Vitamin B fixed dose, Cele+Pre+Vit B, Celecoxib + Vitamin B fixed dose, Cele+Vit B, Pregabalin + Vitamin B fixed dose, Pre+Vit B | Laboratorios Silanes S.A. de C.V. | Chronic Low-back Pain | 01/25 | 02/25 | | |
NCT04647773: To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain |
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| Not yet recruiting | 2/3 | 687 | RoW | HSK16149 20mg BID, HSK16149 40mg BID, HSK16149 60mg BID, HSK16149 80mg BID, Pregabalin 150mg BID, Placebo BID | Haisco Pharmaceutical Group Co., Ltd. | Diabetic Peripheral Neuropathic Pain | 11/22 | 11/22 | | |
2019-000755-14: Trial in healthy subjects to investigate the effect of analgesic drug on pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity. Studio su soggetti sani volto ad indagare gli effetti di farmaci analgesici sulla elaborazione del dolore mediante misure neurofisiologiche del'attività del midollo del midollo spinale e del tronco dell'encefalo |
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| Ongoing | 2 | 56 | Europe | pregabalin, lacosamide, tapentadol, [N03AX16], [N/A], [N02AX06], Capsule, hard, Film-coated tablet, Tablet, LYRICA - 75 MG CAPSULA RIGIDA - USO ORALE 100 CAPSULE IN BLISTER IN UNITA' SEPARABILI PERFORATO (PVC/ALU), VIMPAT - 100 MG - COMPRESSE RIVESTITE CON FILM - USO ORALE - BLISTER (PVC/PVDC/ALU) 14 COMPRESSE, PALEXIA - 50 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN BLISTER PVC/PVDC/AL | UMBERTO I - POLICLINICO DI ROMA, Teva Pharmaceutical Industries LTD, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmbH | Healthy volunteers (intended indication: pain) soggetti sani (indicazione: dolore), Healthy volunteers (intended indication: pain) soggetti sani (indicazione: dolore), Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2019-000942-36: The effects of lacosamide, pregabalin and tapentadol on biomarkers of peripheral pain processing |
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| Not yet recruiting | 2 | 60 | Europe | lacosamide, Pregabalin, Tapentadol, [N02AX06], [N/A], [N03AX16], Tablet, Capsule, Vimpat 100 mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets | Aarhus University, UMBERTO I - POLICLINICO DI ROMA, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmbH, Teva Pharmaceutical Industries LTD | Healthy volunteers (intended indication: pain), Study in healthy volunteers to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2019-001204-37: The effects of lacosamide, pregabalin and tapentadol on biomarkers of pain processing |
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| Not yet recruiting | 2 | 56 | Europe | lacosamide, pregabalin, tapentadol, [N02AX06], [N03AX16], [N/A], Film-coated tablet, Capsule, Tablet, Vimpat 100mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets | Institute of Neuroscience (IoNS), Université catholique de Louvain, UMBERTO I - POLICLINICO DI ROMA, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under Grant Agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmBH, Teva Pharmaceutical Industries LTD | Healthy subjects (intended indication: pain), Study in healthy subjects to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2019-000908-15: The effects of lacosamide, pregabalin and tapentadol on pain processing |
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| Not yet recruiting | 2 | 36 | Europe | lacosamide, Pregabalin, Tapentadol, Tablet, Capsule, Vimpat 100 mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets | Aarhus University, Innovatice Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceutical Industries LTD, Grünenthal GmbH, Teva Pharmaceutical Industries LTD | Healthy volunteers (intended indication: pain), Study in healthy volunteers to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
NCT05763550: To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Herpetic Neuralgia |
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| Completed | 2 | 331 | RoW | HSK16149 20mg BID, HSK16149 40mg BID, Pregabalin 150mg | Haisco Pharmaceutical Group Co., Ltd. | Herpetic Neuralgia | 06/23 | 08/23 | | |
NCT05660538: Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN) |
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| Completed | 2 | 192 | US | VX-548, Suzetrigine, Pregabalin, Placebo (matched to VX-548), Placebo (matched to pregabalin) | Vertex Pharmaceuticals Incorporated | Diabetic Peripheral Neuropathy | 10/23 | 10/23 | | |
JMKX0623-201, NCT06221241: Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic Pain |
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| Recruiting | 2 | 220 | RoW | JMKX000623, Pregabalin, Placebo | Jemincare | Diabetic Peripheral Neuropathic Pain | 03/25 | 04/25 | | |
HSK16149-207, NCT06490484: Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain Who Had an Inadequate Response to Pregabalin |
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| Recruiting | 2 | 90 | RoW | HSK16149 20mg BID, Crisugabalin, Pregabalin 150mg BID, Pregabalin | Haisco Pharmaceutical Group Co., Ltd. | Diabetic Peripheral Neuropathic Pain | 07/24 | 07/24 | | |
NCT05181852: Study to Investigate the Pharmacodynamic Effects of IP2015 in Healthy Male Subjects Using the Intradermal Capsaicin Model |
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| Not yet recruiting | 1 | 24 | NA | IP2015, dose 1, Test drug, IP2015, dose 2, Placebo, Pregabalin, Comparator | Initiator Pharma | Pain | 05/22 | 07/22 | | |
NCT06077786: A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants |
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| Completed | 1 | 26 | Europe | Lu AG06474, Placebo to Lu AG06474, Ibuprofen, Pregabalin, Placebo | H. Lundbeck A/S | Healthy Participants | 05/24 | 05/24 | | |
NCT06600607: Pharmacodynamic Study of 300mg Pregabalin Vs Placebo in Healthy Male Adults |
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| Not yet recruiting | 1 | 20 | RoW | pregabalin 300 mg, Placebo | Latigo Biotherapeutics | Pain Detection, Pain Threshold | 10/24 | 10/24 | | |
NCT05829148: The Effect of Dexmedetomidine, Melatonin and Pregabalin |
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| Not yet recruiting | 1 | 120 | RoW | Dexmedetomidine, Melatonin, Pregabalin, Placebo | Egymedicalpedia | Endoscopic Sinus Surgery | 11/24 | 11/24 | | |
OPTION-VMS, NCT06049797: A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats |
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| Recruiting | N/A | 1000 | US | Fezolinetant, ESN364, VEOZAH, Paroxetine, Citalopram, Escitalopram, Desvenlafaxine, Venlafaxine, Gabapentin, Clonidine, Pregabalin, Oxybutynin, Any other SSRI/SNRI not already specified, Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above | Astellas Pharma Global Development, Inc. | Hot Flashes | 02/26 | 11/26 | | |