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| Not yet recruiting | 3 | 160 | | | University of Technology Sydney, NHMRC | Neuropathic Cancer Pain; Cancer | | | | |
| Recruiting | 3 | 84 | | | University of Technology Sydney, NHMRC | Neuropathic Cancer Pain, Cancer | | | | |
2013-004313-41: Effect of pre-operative pain treatment on postoperative outcome after total hip or knee replacement surgery Effecten van pre-operatieve pijnbehandeling op postoperatieve uitkomsten na totale heup- of knievervanging |
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| Ongoing | 3 | 118 | Europe | Gastro-resistant capsule, hard, Cymbalta | UMCG, Stichting ARGON (reumafonds "Dutch Arthritis Foundation") | Osteoarthritis (knee or hip) Artrose (knie of heup), degenerative joint disease (knee or hip) gewrichtsslijtage (knie of heup), Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2004-001237-42: Open-Label Duloxetine Extension phase in Patients Who Have Completed the F1J-MC-HMDG Clinical TrialFase de extensión abierta con duloxetina en aquellos pacientes que hayan finalizado el ensayo clínico F1J-MC-HMDG |
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| Ongoing | 3 | 150 | Europe | Duloxetine Hydrochloride, LY248686, | Lilly S.A. | Major Depressive Disorder | | | | |
2008-000968-16: EFFICACY OF DULOXETINE IN THE TREATMENT OF URINARY INCONTINENCEAFTER PROSTATECTOMIE DUE TO CANCER |
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| Ongoing | 3 | 90 | Europe | duloxetine, duloxetine, YENTREVE, YENTREVE | CeRePP | We want to evaluate the effect of Duloxetine 40mg BID (80mg daily dose) on the number of urinary incontinence episodes as shown on a 74 days bladder diary, compared to placebo for male which had a prostatectomy due to cancer. We\'ll also study tolerance and efficacy of duloxetine with Qol questionnaires. | | | | |
2010-018650-12: Evaluation du système noradrénergique dans l’altération de la perception douloureuse chez le patient Parkinsonien |
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| Ongoing | 3 | 36 | Europe | duloxetine, apomorphine, levodopa, dompéridone, CYMBALTA, APOKINON, MODOPAR, MOTILIUM, CYMBALTA, APOKINON, MODOPAR, MOTILIUM | CHU de Toulouse | maladie de Parkinson | | | | |
2015-001669-16: Duloxetine for chronic osteoarthritis pain; an important alternative? Duloxetine voor chronische pijn bij artrose; is het een belangrijk alternatief? |
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| Ongoing | 3 | 224 | Europe | Capsule, hard, Duloxetine | Erasmus MC, ZonMW | osteoarthritis artrose, osteoarthritis artrose, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2013-004881-33: Multicentre trial in to investigate the usage of antidepressant and antipsychotics (with / without approval) in patients at the age of children and adolescents Groß an gelegte, einfache offene klinische Studie mit mehreren teilnehmenden Prüfzentren zur Anwendung von Antidepressiva und Neuroleptika (mit /ohne Zulassung) |
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| Ongoing | 3 | 1000 | Europe | Tablet, Abilify, Zyprexa, Leponex, Seroquel, Risperdal, Zeldox, Melneurin, Dipiperon, Saroten, Cipramil, Anafranil, Aponal, Cymbalta, Cipralex, Fluctin, Fevarin, Tofranil, Ludiomil, Remergil, Nortrilen, Paroxat, Zoloft, Stangyl, Trevilor | Universitätsklinikum Würzburg, Kompetenznetz TDM-KJP e.V., BfArM | therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2016-003146-89: Optimal pathway for treating neuropathic pain in diabetes mellitus. |
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| Ongoing | 3 | 392 | Europe | Amitriptyline 25mg, Duloxetine, Pregabalin, Capsule, Gastro-resistant capsule, hard, , Amitriptyline 25mg, Duloxetine, Pregabalin 75mg | Sheffield Teaching Hospitals NHS Foundation Trust | Diabetic peripheral neuropathic pain., Painful nerve damage as a result of diabetes., Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT03538691 / 2018-000601-22: A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder |
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| Completed | 3 | 1149 | US | Brexpiprazole, OPC-34712, Rexulti, Antidepressant therapy | Otsuka Pharmaceutical Development & Commercialization, Inc. | Major Depressive Disorder | 07/22 | 07/22 | | |
| Withdrawn | 3 | 80 | US | Duloxetine, Cymbalta, Placebo | University of Utah | Major Depressive Disorder | 05/23 | 05/23 | | |
NCT06025474: Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome |
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| Recruiting | 3 | 203 | Europe | Vortioxetine 20Mg Tab, Brintellix, Paroxetine 20 Mg Oral Tablet, Sertraline 50 MG, Citalopram 20mg, Escitalopram 10mg, Duloxetine 60 MG, Pregabalin 75mg | Federico II University | Burning Mouth Syndrome | 10/23 | 07/24 | | |
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain |
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| Recruiting | 3 | 1800 | US | Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices | Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Knee Osteoarthritis | 11/24 | 03/25 | | |
GENDOLCAT3, NCT06606067: Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High Risk |
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| Active, not recruiting | 3 | 294 | Europe | Duloxetine, Placebo | Parc de Salut Mar, Carlos III Health Institute | Chronic Post-surgical Pain | 07/26 | 12/26 | | |
NCT06407401: Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Patients With Early Breast Cancer |
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| Not yet recruiting | 3 | 399 | NA | Duloxetine 60 MG, Furosemide 40 mg, Booklet for healthy behaviors | European Organisation for Research and Treatment of Cancer - EORTC | ER+ Breast Cancer, HER2-negative Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, Drug-Related Side Effects and Adverse Reactions, Musculoskeletal Pain | 04/28 | 11/28 | | |
NCT05677295: Therapeutic Efficacy in Women With Stress Urinary Incontinence |
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| Recruiting | 3 | 90 | RoW | duloxetine, Imipramine | Far Eastern Memorial Hospital | Women With Stress Urinary Incontinence | 12/24 | 12/24 | | |
INTENSIFY BD, NCT05973786: The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. |
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| Recruiting | 3 | 418 | Europe | Escitalopram, ATC code: N06AB10, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04 | Dr. Inge Winter, Universität Münster | Bipolar Depression | 06/26 | 06/26 | | |
INTENSIFY, NCT05603104: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure |
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| Recruiting | 3 | 1254 | RoW | Clozapine, ATC code: N05AH02, Esketamine Nasal Product, ATC code: N06AB10, Escitalopram, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04, Second-line Antidepressants, Second-line Antipsychotics, Ketamine Hydrochloride, N01AX03, Esketamine hydrochloride, N015X14 | Dr. Inge Winter, Universität Münster | Schizophrenia and Related Disorders, Major Depressive Disorder, Bipolar Depression | 06/26 | 06/26 | | |
CAPNEUCHIM, NCT05840562: Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy |
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| Recruiting | 3 | 274 | Europe | Capsaicin, Qutenza, Duloxetine, Cymbalta | Institut Cancerologie de l'Ouest, Grünenthal GmbH | Chemotherapy-induced Peripheral Neuropathy | 03/27 | 03/27 | | |
| Not yet recruiting | 2/3 | 50 | NA | methadone, metadol, duloxetine, cymbalta | University of British Columbia, British Columbia Cancer Agency | Chemotherapy-induced Peripheral Neuropathy | 02/26 | 02/26 | | |
NCT04137107: Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer |
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| Active, not recruiting | 2/3 | 220 | US, RoW | Oxaliplatin, Duloxetine Hydrochloride, Duloxetine, Quality-of-Life Assessment, Questionnaire Administration, Placebo | Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI) | Stage II Colorectal Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8 | 02/25 | 12/25 | | |
| Recruiting | 2/3 | 330 | US | Antidepressant, AD: aripiprazole, bupropion, duloxetine, escitalopram, mirtazapine, sertraline, venlafaxine, Enhanced Fear Avoidance Rehabilitation, EFAR | Ajay Wasan, MD, Msc, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Brigham and Women's Hospital, Mayo Clinic | Chronic Low Back Pain, Negative Affectivity | 12/25 | 04/26 | | |
